基本情報
- 所属
- 自治医科大学 外科学講座(小児外科部門) 教授
- 学位
- Stat3はMn-SODを介して肝細胞における低酸素再酸素化傷害を抑制する(2005年3月 千葉大学)
- J-GLOBAL ID
- 201601010421619629
- researchmap会員ID
- B000250759
- 外部リンク
研究キーワード
11研究分野
1経歴
2-
2023年10月 - 現在
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2015年
学歴
1-
1992年4月 - 1998年3月
論文
212-
Pediatrics International 58(9) 877-80 2016年 査読有り
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Cancer Science 107(3) 233-41 2016年 査読有り
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Journal of Pediatric Surgery 51(12) 1926-1930 2016年 査読有り
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World journal of gastrointestinal endoscopy 7(3) 183-91 2015年3月 査読有りCongenital esophageal stenosis (CES) is an extremely rare malformation, and standard treatment have not been completely established. By years of clinical research, evidence has been accumulated. We conducted systematic review to assess outcomes of the treatment for CES, especially the role of endoscopic modalities. A total of 144 literatures were screened and reviewed. CES was categorized in fibromuscular thickening, tracheobronchial remnants (TBR) and membranous web, and the frequency was 54%, 30% and 16%, respectively. Therapeutic option includes surgery and dilatation, and surgery tends to be reserved for ineffective dilatation. An essential point is that dilatation for TBR type of CES has low success rate and high rate of perforation. TBR can be distinguished by using endoscopic ultrasonography (EUS). Overall success rate of dilatation for CES with or without case selection by using EUS was 90% and 29%, respectively. Overall rate of perforation with or without case selection was 7% and 24%, respectively. By case selection using EUS, high success rate with low rate of perforation could be achieved. In conclusion, endoscopic dilatation has been established as a primary therapy for CES except TBR type. Repetitive dilatation with gradual step-up might be one of safe ways to minimize the risk of perforation.
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Pediatric Surgery International 31(10) 891-7 2015年 査読有り
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Journal of Pediatric Surgery 50(8) 1398-404 2015年 査読有り
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European Journal of Pediatric Surgery 25(1) 9-14 2015年 査読有り
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Pediatric Blood and Cancer 62(7) 1297-9 2015年 査読有り
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Pediatric Reports 7(2) 5795-5795 2015年 査読有り
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European Journal of Pediatric Surgery 26(1) 60-6 2015年 査読有り
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Pediatric Reports 7(1) 5578-5578 2015年 査読有り
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Journal of Medical Case Reports 9(1) 23-23 2015年 査読有り
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Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 20 654-8 2014年 査読有り
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Journal of Pediatric Gastroenterology and Nutrition 59(2) 204-9 2014年 査読有り
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Pediatric Surgery International 30(11) 1129-34 2014年 査読有り
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Pediatric Surgery International 30(9) 919-26 2014年 査読有り
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Pediatric reports 5(4) e17 2013年11月 査読有りThe aim of this paper is to investigate the clinical courses of patients with biliary atresia (BA) during neonatal period. We examined 19 patients with BA, who underwent blood tests including direct bilirubin (D-Bil) within 20 days of age, in 3 tertiary hospitals in Japan. The first blood sample was collected at 8.4±6.5 days of age. The acholic stool was observed within 2 weeks of age in 16 cases (84.2%). Decrease of T-Bil was observed in all the subjects, with a range of reduction of 6.5±3.3 mg/dL, from 10.4±7.5 to 29.8±9.1 days of age. Decrease of D-Bil was also observed in 17 out of 19 cases (89%), with a range of reduction of 1.1±1.0 mg/dL, from 15.5±8.0 to 24.9±9.6 days of age. A significant decrease of D-Bil was observed in 2 cases of biliary atresia splenic malformation syndrome. We therefore conclude that clinicians treating icteric infants should not exclude a diagnosis of BA even if the level of D-Bil has a declining tendency.
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No shinkei geka. Neurological surgery 41(7) 601-7 2013年7月Microvascular decompression is now a standard surgical technique for the treatment of trigeminal neuralgia. However, it is occasionally difficult to expose the trigeminal nerves because of the high anatomical variety of vascular or bony structures in the posterior fossa. We reported the case of a 59-year-old woman with trigeminal neuralgia whose site of neurovascular compression could not be observed in microvascular decompression. On approaching the trigeminal nerve, the suprameatal tubercle was so prominent that it prevented adequate visualization of the nerve tract. After drilling out the tubercle concealing the trigeminal nerve behind it, we exposed the nerve entirely and subsequently decompressed it from the superior cerebellar artery. Retrospectively, the suprameatal tubercle was found 3mm high above the posterior surface of the petrous bone. Then, we analyzed the height of suprameatal tubercles in 106 patients who underwent three-dimensional CT of the skull. Mean values of the suprameatal tubercles were 1.4-1.7mm in height, and 5.2% of them were higher than 3mm. The result suggested the high morphological variety of the petrous bone. We emphasize the importance of presurgical evaluation of the petrous bone in trigeminal neuralgia, because the neurovascular compression site may not be exposed sufficiently by the suprameatal tubercle in approximately 5% of the patients.
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Journal of Dermatology 40(3) 226-8 2013年 査読有り
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BMC Pediatrics 13(1) 205-205 2013年 査読有り
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Pediatric Reports 5(4) 73-75 2013年 査読有り
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Pediatric Surgery International 28(1) 9-14 2012年 査読有り
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Clinical nuclear medicine 36(10) 950-951 2011年10月 査読有り
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Journal of Pediatric Gastroenterology and Nutrition 53(6) 620-6 2011年 査読有り
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Journal of Perinatology 31(4) 269-273 2011年 査読有り
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Comparative Hepatology 10 6-6 2011年 査読有り
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Surgery 149(4) 569-575 2011年 査読有り
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Pediatric Surgery International 27(3) 309-314 2011年 査読有り
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Pediatric Surgery International 27(1) 29-33 2011年 査読有り
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Clinical nuclear medicine 36(10) 950-1 2011年 査読有り
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No shinkei geka. Neurological surgery 38(6) 545-50 2010年6月Cerebral aneurysms arising from fenestration of the horizontal (A(1)) segment in the anterior cerebral artery (ACA) are very rare. In this paper, we report our case, discuss radiological features, and review previous cases. A 70-year-old male was referred to our hospital presenting with memory disturbance. His unruptured cerebral aneurysm in the A(1) segment was incidentally found by magnetic resonance angiography (MRA). Three dimensional computed tomographic angiography (3D-CTA) demonstrated this aneurysm arising from fenestration of the A(1) segment. Surgical neck clipping was performed via the pterional approach, while sacrificing one pair of the A(1) segment. The patient's post operative course was uneventful. Only 14 cases with an aneurysm arising from fenestration of the A(1) segment have been reported previously. In the present case, 3D-CTA was very useful for finding out where the aneurysm arose from, and we also had to be careful about perforating arteries from the A(1) segment during the surgery.
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Pediatric Surgery International 26(4) 419-422 2010年 査読有り
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Journal of Pediatric Surgery 45(12) 2293-2298 2010年 査読有り
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Journal of Pediatric Surgery 45(9) 1887-1889 2010年 査読有り
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Antioxidants and Redox Signaling 11(10) 2563-2572 2009年 査読有り
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Pediatric Surgery International 25(6) 531-533 2009年 査読有り
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Pediatric Research 66(2) 149-154 2009年 査読有り
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Journal of Pediatric Surgery 43(9) E1-E3 2008年 査読有り
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Journal of Pediatric Surgery 43(3) 495-499 2008年 査読有り
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Journal of Hepatology 48(3) 422-432 2008年 査読有り
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Journal of Pediatric Surgery 43(10) e19-22 2008年 査読有り
MISC
705共同研究・競争的資金等の研究課題
13-
日本学術振興会 科学研究費助成事業 2024年4月 - 2029年3月
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日本学術振興会 科学研究費助成事業 2024年4月 - 2027年3月
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日本学術振興会 科学研究費助成事業 2023年4月 - 2026年3月
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日本学術振興会 科学研究費助成事業 基盤研究(C) 2022年4月 - 2025年3月
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日本学術振興会 科学研究費助成事業 基盤研究(C) 2021年4月 - 2024年3月