Seasonal variation in blood pressure: current evidence and recommendations for hypertension management.

Keisuke Narita, Satoshi Hoshide, Kazuomi Kario

Hypertension research : official journal of the Japanese Society of Hypertension 44(11) 1363-1372 2021年11月

Blood pressure (BP) exhibits seasonal variation, with an elevation of daytime BP in winter and an elevation of nighttime BP in summer. The wintertime elevation of daytime BP is largely attributable to cold temperatures. The summertime elevation of nighttime BP is not due mainly to temperature; rather, it is considered to be related to physical discomfort and poor sleep quality due to the summer weather. The winter elevation of daytime BP is likely to be associated with the increased incidence of cardiovascular disease (CVD) events in winter compared to other seasons. The suppression of excess seasonal BP changes, especially the wintertime elevation of daytime BP and the summertime elevation of nighttime BP, would contribute to the prevention of CVD events. Herein, we review the literature on seasonal variations in BP, and we recommend the following measures for suppressing excess seasonal BP changes as part of a regimen to manage hypertension: (1) out-of-office BP monitoring, especially home BP measurements, throughout the year to evaluate seasonal variations in BP; (2) the early titration and tapering of antihypertensive medications before winter and summer; (3) the optimization of environmental factors such as room temperature and housing conditions; and (4) the use of information and communication technology-based medicine to evaluate seasonal variations in BP and provide early therapeutic intervention. Seasonal BP variations are an important treatment target for the prevention of CVD through the management of hypertension, and further research is necessary to clarify these variations.
Reproducibility of nighttime home blood pressure measured by a wrist-type nocturnal home blood pressure monitoring device

Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario

Journal of Clinical Hypertension 23(10) 1872-1878 2021年10月1日
Effect of Heart Rate on the Outcome of Renal Denervation in Patients With Uncontrolled Hypertension

Michael Böhm, Konstantinos Tsioufis, David E. Kandzari, Kazuomi Kario, Michael A. Weber, Roland E. Schmieder, Raymond R. Townsend, Saarraaken Kulenthiran, Christian Ukena, Stuart Pocock, Sebastian Ewen, Joachim Weil, Martin Fahy, Felix Mahfoud

Journal of the American College of Cardiology 78(10) 1028-1038 2021年9月7日
Nighttime home blood pressure as a mediator of N-terminal pro-brain natriuretic peptide in cardiovascular events

Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

Hypertension Research 44(9) 1138-1146 2021年9月1日
The long-term prognostic factors in hemodialysis patients with acute coronary syndrome: perspectives from sarcopenia and malnutrition

Hisaya Kobayashi, Masao Takahashi, Motoki Fukutomi, Yusuke Oba, Hiroshi Funayama, Kazuomi Kario

Heart and Vessels 36(9) 1275-1282 2021年9月1日
Relationship Between Home Blood Pressure and the Onset Season of Cardiovascular Events: The J-HOP Study (Japan Morning Surge-Home Blood Pressure).

Keisuke Narita, Satoshi Hoshide, Kazuomi Kario

American journal of hypertension 34(7) 729-736 2021年8月9日

BACKGROUND: The incidence of cardiovascular disease (CVD) increases during winter. The risk that elevated home blood pressure (BP) poses for CVD events that occur in each of 4 seasons is unclear. We conducted a post hoc analysis using the dataset from a nationwide cohort, the Japan Morning Surge-Home Blood Pressure (J-HOP) study, to assess the association between home BP and winter-onset CVD events. METHODS: J-HOP participants who had cardiovascular risks conducted morning and evening home BP measurements for a 14-day period and were followed-up for the occurrence of CVD events. RESULTS: We analyzed 4,258 participants (mean age 64.9 years; 47% male; 92% hypertensives) who were followed-up for an average of 6.2 ± 3.8 years (26,295 person-years). We divided the total of 269 CVD events (10.2/1,000 person-years) by the season of onset as follows: 82 in the winter and 187 in the other seasons (spring, summer, and autumn). In the Cox models adjusted for covariates and the season when home BPs were measured at baseline, morning home systolic BP (SBP) was associated with both winter-onset and other season-onset CVD events: hazard ratio (HR) for winter 1.22, 95% confidence interval (CI) 1.06-1.42 per 10 mm Hg; HR for other seasons 1.11, 95% CI 1.00-1.23. Evening home SBP was associated with the other season-onset CVD events (HR 1.20, 95% CI 1.08-1.33 per 10 mm Hg), but not with the winter-onset CVD events. CONCLUSIONS: Our findings indicate that compared with evening home BP, morning home BP might be a superior predictor of winter-onset CVD events.
Impact of home blood pressure variability on cardiovascular outcome in patients with arterial stiffness: Results of the J-HOP study

Yusuke Ishiyama, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

Journal of Clinical Hypertension 23(8) 1529-1537 2021年8月1日
Seasonal Variation in Masked Nocturnal Hypertension: The J-HOP Nocturnal Blood Pressure Study.

Keisuke Narita, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

American journal of hypertension 34(6) 609-618 2021年6月22日

BACKGROUND: Little is known about seasonal variation in nighttime blood pressure (BP) measured by a home device. In this cross-sectional study, we sought to assess seasonal variation in nighttime home BP using data from the nationwide, practice-based Japan Morning Surge-Home BP (J-HOP) Nocturnal BP study. METHODS: In this study, 2,544 outpatients (mean age 63 years; hypertensives 92%) with cardiovascular risks underwent morning, evening, and nighttime home BP measurements (measured at 2:00, 3:00, and 4:00 am) using validated, automatic, and oscillometric home BP devices. RESULTS: Our analysis showed that nighttime home systolic BP (SBP) was higher in summer than in other seasons (summer, 123.3 ± 14.6 mmHg vs. spring, 120.7 ± 14.8 mmHg; autumn, 121.1 ± 14.8 mmHg; winter, 119.3 ± 14.0 mmHg; all P<0.05). Moreover, we assessed seasonal variation in the prevalence of elevated nighttime home SBP (≥120 mmHg) in patients with non-elevated daytime home SBP (average of morning and evening home SBP <135 mmHg; n = 1,565), i.e., masked nocturnal hypertension, which was highest in summer (summer, 45.6% vs. spring, 27.2%; autumn, 28.8%; winter, 24.9%; all P<0.05). Even in intensively controlled morning home SBP (<125 mmHg), the prevalence of masked nocturnal hypertension was higher in summer (summer, 27.4% vs. spring, 14.2%; autumn, 8.9%; winter, 9.0%; all P<0.05). The urine albumin-creatinine ratio in patients with masked nocturnal hypertension tended to be higher than that in patients with non-elevated both daytime and nighttime SBP throughout each season. CONCLUSIONS: The prevalence of masked nocturnal hypertension was higher in summer than other seasons and the difference proved to be clinically meaningful.
Changes in Plasma Renin Activity After Renal Artery Sympathetic Denervation

Felix Mahfoud, Raymond R. Townsend, David E. Kandzari, Kazuomi Kario, Roland E. Schmieder, Konstantinos Tsioufis, Stuart Pocock, Shukri David, Kiritkumar Patel, Anjani Rao, Antony Walton, Jason E. Bloom, Thomas Weber, Markus Suppan, Lucas Lauder, Sidney A. Cohen, Pamela McKenna, Martin Fahy, Michael Böhm, Michael A. Weber

Journal of the American College of Cardiology 77(23) 2909-2919 2021年6月15日
Comparison of nighttime measurement schedules using a wrist-type nocturnal home blood pressure monitoring device

Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario

Journal of Clinical Hypertension 23(6) 1144-1149 2021年6月1日
ダサチニブによる薬剤性肺動脈性肺高血圧症と薬剤用量の関連性

久保田香菜, 今井靖, 翁家国, 上野修市, 神田善伸, 苅尾七臣

日本肺高血圧・肺循環学会学術集会・日本小児肺循環研究会プログラム・抄録集 6回・27回 2-2 2021年5月
Assessment of a new algorithm to detect atrial fibrillation in home blood pressure monitoring device among healthy adults and patients with atrial fibrillation

Tomonori Watanabe, Naoko Tomitani, Nobuhiko Yasui, Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario

Journal of Clinical Hypertension 23(5) 1085-1088 2021年5月1日
Effect of renal denervation in attenuating the stress of morning surge in blood pressure: post-hoc analysis from the SPYRAL HTN-ON MED trial

Kazuomi Kario, Michael A. Weber, Michael Böhm, Raymond R. Townsend, Felix Mahfoud, Roland E. Schmieder, Konstantinos Tsioufis, Sidney A. Cohen, Martin Fahy, David E. Kandzari

Clinical Research in Cardiology 110(5) 725-731 2021年5月1日
Stress-Induced Blood Pressure Elevation Self-Measured by a Wearable Watch-Type Device

Naoko Tomitani, Hiroshi Kanegae, Yuka Suzuki, Mitsuo Kuwabara, Kazuomi Kario

American Journal of Hypertension 34(4) 377-382 2021年4月1日
Safety and efficacy of empagliflozin in elderly Japanese patients with type 2 diabetes mellitus: A post hoc analysis of data from the SACRA study

Kenta Okada, Satoshi Hoshide, Mitsutoshi Kato, Hiroshi Kanegae, Shun Ishibashi, Kazuomi Kario

Journal of Clinical Hypertension 23(4) 860-869 2021年4月1日
【診断と治療の手技-診察室これ1冊-】(第1部)診断(第1章) 問診・意識・身体診察血圧測定と評価

成田圭佑, 苅尾七臣

診断と治療 109(Suppl.) 18-21 2021年3月
成人先天性心疾患に合併した不整脈に対する包括的アプローチ(Comprehensive Approach for Arrhythmia Complicated with Adult Congenital Heart Disease)

今井靖, 甲谷友幸, 久保田香菜, 渡部智紀, 上岡正志, 渡邉裕昭, 小森孝洋, 横田彩子, 奥山貴文, 苅尾七臣, 河田政明

日本循環器学会学術集会抄録集 85回 SS22-3 2021年3月
遅速型房室結節リエントリー性頻拍のクライオアブレーションにおけるslow pathway potentialのlast deflection mappingの有用性(Utility of Last Deflection Mapping of Slow Pathway Potential for Cryoablation in Slow-fast Atrioventricular Nodal Reentrant Tachycardia)

渡部智紀, 奥山貴文, 渡邉裕昭, 横田彩子, 上岡正志, 小森孝洋, 甲谷友幸, 今井靖, 苅尾七臣

日本循環器学会学術集会抄録集 85回 FRS5-3 2021年3月
自動計測したP波のノッチによるカテーテルアブレーション施行患者の心房細動の再発予測(The Automatically Assessed P-wave Notch Predicts the Recurrence of AF in Patients Who Have Undergone Catheter Ablation)

奥山貴文, 甲谷友幸, 渡邉裕昭, 横田彩子, 上岡正志, 渡部智紀, 小森孝洋, 今井靖, 苅尾七臣

日本循環器学会学術集会抄録集 85回 OJ46-3 2021年3月
経カテーテル大動脈弁留置術後の認知機能の経時的変化(Serial Changes in Cognitive Function Following Transcatheter Aortic Valve Implantation)

船山大, 大場祐輔, 高橋政夫, 苅尾七臣

日本循環器学会学術集会抄録集 85回 OJ88-1 2021年3月
Comparative effects of valsartan plus cilnidipine or hydrochlorothiazide on nocturnal home blood pressure

Takeshi Fujiwara, Satoshi Hoshide, Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario

Journal of Clinical Hypertension 23(3) 687-691 2021年3月1日
Atrial fibrillation is associated with cardiovascular events in obese Japanese with one or more cardiovascular risk factors: The Japan Morning Surge Home Blood Pressure (J-HOP) Study

Hiroaki Watanabe, Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario

Journal of Clinical Hypertension 23(3) 665-671 2021年3月1日
Differences in ambulatory blood pressure profiles between Japanese and Thai patients with hypertension /suspected hypertension

Naoko Tomitani, Sirisawat Wanthong, Weranuj Roubsanthisuk, Peera Buranakitjaroen, Satoshi Hoshide, Kazuomi Kario

Journal of Clinical Hypertension 23(3) 614-620 2021年3月1日
【外来における救急診療のポイント】高血圧緊急症

成田圭佑, 苅尾七臣

臨牀と研究 98(2) 205-210 2021年2月
治療方針に難渋した金属アレルギーを有する狭心症の一例

鳥海進一, 大場祐輔, 清水勇人, 高橋政夫, 船山大, 苅尾七臣

日本心血管インターベンション治療学会抄録集 29回 769-769 2021年2月
Different age-related impacts of lean and obesity on cardiovascular prognosis in Japanese patients with cardiovascular risks: The J-HOP (Japan Morning Surge-Home Blood Pressure) Study

Shinichi Toriumi, Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario

Journal of Clinical Hypertension 23(2) 382-388 2021年2月1日
Automatically assessed P-wave predicts cardiac events independently of left atrial enlargement in patients with cardiovascular risks: The Japan Morning Surge-Home Blood Pressure Study

Ayako Yokota, Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario

Journal of Clinical Hypertension 23(2) 301-308 2021年2月1日
Association of lower nighttime diastolic blood pressure and hypoxia with silent myocardial injury: The Japan Morning Surge-Home Blood Pressure study

Kana Kubota, Satoshi Hoshide, Kazuomi Kario

Journal of Clinical Hypertension 23(2) 272-280 2021年2月1日
Accurate nighttime blood pressure monitoring with less sleep disturbance

Naoko Tomitani, Satoshi Hoshide, Kazuomi Kario

Hypertension Research 2021年
Clinical Impact of the Maximum Mean Value of Home Blood Pressure on Cardiovascular Outcomes: A Novel Indicator of Home Blood Pressure Variability

Takeshi Fujiwara, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

Hypertension 840-850 2021年
Sleep and cardiovascular outcomes in relation to nocturnal hypertension: the J-HOP Nocturnal Blood Pressure Study

Kazuomi Kario, Satoshi Hoshide, Michiaki Nagai, Yukie Okawara, Hiroshi Kanegae

Hypertension Research 2021年
Self-measured worksite blood pressure and its association with organ damage in working adults: Japan Morning Surge Home Blood Pressure (J-HOP) worksite study

Naoko Tomitani, Satoshi Hoshide, Kazuomi Kario

Journal of Clinical Hypertension 23(1) 53-60 2021年1月1日
Cardiovascular outcome and home blood pressure in relation to silent myocardial ischemia in a clinical population: The J-HOP study

Hayato Shimizu, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

Journal of Clinical Hypertension 22(12) 2214-2220 2020年12月1日
眼内炎を契機に診断された感染性心内膜炎の2症例

石山裕介, 原田顕治, 青山泰, 脇広昂, 大場祐輔, 山中祐子, 小形幸代, 苅尾七臣

超音波医学 47(Suppl.) S248-S248 2020年11月
The possibility that long-term isometric handgrip exercise contributes to left atrial enlargement in patients with hypertension

Yuta Kemi, Satoshi Hoshide, Eiji Yamashita, Kazuomi Kario

Journal of Clinical Hypertension 22(11) 2137-2140 2020年11月1日
Associations between day-by-day home blood pressure variability and renal function and albuminuria in patients with and without diabetes

Daisuke Suzuki, Satoshi Hoshide, Kazuomi Kario

American Journal of Hypertension 33(9) 860-868 2020年9月10日
Comparison of Morphological Patterns Between In-Stent Restenosis Lesions of Overlapping and Non-Overlapping Second- and Third-Generation Stents Using Optical Frequency Domain Imaging

Seigo Arima, Hiroshi Funayama, Motoki Fukutomi, Yukako Ogoyama, Yusuke Oba, Masao Takahashi, Kazuomi Kario

Cardiovascular Revascularization Medicine 21(9) 1108-1112 2020年9月1日
Seasonal Variation of Home Blood Pressure and Its Association With Target Organ Damage: The J-HOP Study (Japan Morning Surge-Home Blood Pressure).

Keisuke Narita, Satoshi Hoshide, Takeshi Fujiwara, Hiroshi Kanegae, Kazuomi Kario

American journal of hypertension 33(7) 620-628 2020年7月18日

BACKGROUND: Although seasonal variation of home blood pressure (BP) has been reported to be higher in winter, seasonal difference in home BP (HBP) and its association with target organ damage (TOD) remains unclear. METHODS: This is a cross-sectional study using the dataset from the Japan Morning Surge-Home Blood Pressure (J-HOP) study to assess seasonal differences in HBP, prevalence of masked hypertension, and association of HBP with TOD. The J-HOP study is a nationwide, multicenter prospective study whose participants with cardiovascular risks underwent morning and evening HBP measurements for a 14-day period in 71 institutions throughout Japan. Urine albumin-creatinine ratio (UACR) and serum-B-type natriuretic peptide (BNP) were obtained at enrollment. RESULTS: Among 4,267 participants (mean age, 64.9 ± 10.9 years; 46.9% male; 91.4% hypertensives), 1,060, 979, 1,224, and 1,004 participants were enrolled in spring, summer, autumn, and winter, respectively. Morning and evening home systolic/diastolic BP levels, and prevalence of masked hypertension (office BP <140/90 mm Hg and HBP ≥135/85 mm Hg) were significantly lower in summer than other seasons after adjustment for covariates. When we assessed the interaction between BP parameters and each season for an association with TOD, we found the association between morning home diastolic BP and each of UACR and BNP was stronger in winter than other seasons (both P for interaction <0.05). CONCLUSIONS: In this study, we revealed that the prevalence of masked hypertension was higher in other seasons than in summer and found a notable association between morning home diastolic BP and TOD in winter.
Cardiovascular Event Risks Associated with Masked Nocturnal Hypertension Defined by Home Blood Pressure Monitoring in the J-HOP Nocturnal Blood Pressure Study

Takeshi Fujiwara, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

Hypertension 76(1) 259-266 2020年7月1日
Age-related difference of the association of cardiovascular risk factors with the cardio-ankle vascular index in the Cardiovascular Prognostic Coupling Study in Japan (the Coupling Registry).

Tomoyuki Kabutoya, Satoshi Hoshide, Takeshi Fujiwara, Keita Negishi, Masafumi Nishizawa, Mitsuyoshi Yamamoto, Kayo Yamagiwa, Akihiro Kawashima, Tetsuro Yoshida, Jun Nakazato, Yoshio Matsui, Hiromitsu Sekizuka, Hideyasu Abe, Yasuhisa Abe, Yumiko Fujita, Kei Sato, Keisuke Narita, Norihiro Tsuchiya, Yoshiaki Kubota, Toshikazu Hashizume, Kazuomi Kario

Journal of clinical hypertension (Greenwich, Conn.) 22(7) 1208-1215 2020年7月

The value of the cardio-ankle vascular index (CAVI) increases with age. All large-scale studies of the CAVI have investigated patients <80 years old. Thus, the clinical characteristics of high CAVI in patients aged 80 or more remain unclear. Therefore, we investigated (1) the CAVI in very elderly patients and (2) the determinants of a high CAVI in high-risk patients, including very elderly patients. The Cardiovascular Prognostic Coupling Study in Japan (Coupling Registry) is a prospective observational study of Japanese outpatients with any cardiovascular risk factors. We enrolled 5109 patients from 30 institutions (average age 68.7 ± 11.4 years, 52.4% males). We investigated the determinants of the CAVI by separating the patients into three groups: 970 middle-aged (<60 years), 3252 elderly (60-79 years), and 887 very elderly (≥80 years) patients. The CAVI values of the males were significantly higher those of the females in all age groups (<60 years: 7.81 ± 1.11 vs. 7.38 ± 0.99, P < .001; 60-79 years: 9.20 ± 1.29 vs. 8.66 ± 1.07, P < .001; ≥80 years: 10.26 ± 1.39 vs. 9.51 ± 1.12, P < .001). In all age groups, the CAVI of the patients with diabetes/glucose tolerance disorder was higher than that of the patients without diabetes/glucose tolerance disorder (<60 years: 7.82 ± 1.22 vs 7.58 ± 1.03, P = .002; 60-79 years: 9.23 ± 1.20 vs 8.78 ± 1.19, P < .001; ≥80 years: 10.04 ± 1.24 vs 9.75 ± 1.32, P = .002). The determinants of the CAVI in these very elderly patients were age, male sex, low BMI, and mean blood pressure. Diabetes/glucose tolerance disorder and glucose were independently associated with the CAVI in the patients aged <60 years and 60-79 years, but not in those aged ≥80 years after adjusting for other covariates.
Should We Protect the Coronary Artery During Transcatheter Aortic Valve Replacement in Quadricuspid Valve Patients?

Masao Takahashi, Kei Aizawa, Yusuke Oba, Hiroshi Funayama, Koji Kawahito, Kazuomi Kario

JACC: Cardiovascular Interventions 13(12) 1492-1494 2020年6月22日
Mobile mural thrombus and spontaneous echo contrast in ascending aorta after postoperative adjuvant cisplatin-based chemotherapy

Yutaka Aoyama, Kenji Harada, Yasuhiro Yokoyama, Yusuke Ishiyama, Takahiro Komori, Masahisa Shimpo, Kazuomi Kario

Echocardiography 37(6) 928-929 2020年6月1日
Increased Arterial Stiffness Amplifies the Association between Home Blood Pressure Variability and Cardiac Overload: The J-HOP Study

Yusuke Ishiyama, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

Hypertension 75(6) 1600-1606 2020年6月1日
Prognostic Value of a Riser Pattern of Nighttime Blood Pressure in Very Elderly Adults of ≥80 Years: A General Practice-Based Prospective SEARCH Study

Takeshi Fujiwara, Satoshi Hoshide, Hiroshi Kanegae, Kazuomi Kario

American Journal of Hypertension 33(6) 520-527 2020年5月21日
Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial

Michael Böhm, Kazuomi Kario, David E Kandzari, Felix Mahfoud, Michael A Weber, Roland E Schmieder, Konstantinos Tsioufis, Stuart Pocock, Dimitris Konstantinidis, James W Choi, Cara East, David P Lee, Adrian Ma, Sebastian Ewen, Debbie L Cohen, Robert Wilensky, Chandan M Devireddy, Janice Lea, Axel Schmid, Joachim Weil, Tolga Agdirlioglu, Denise Reedus, Brian K Jefferson, David Reyes, Richard D'Souza, Andrew S P Sharp, Faisal Sharif, Martin Fahy, Vanessa DeBruin, Sidney A Cohen, Sandeep Brar, Raymond R Townsend, Ertan Akarca, Suhail Allaqaband, Eirini Andrikou, Jiro Aoki, Ahran Arnold, Herbert Aronow, Masahiko Asami, William Bachinsky, John Barton, Kyle Bass, Bryan Batson, Chris Bell, Barry Bertolet, Yvonne Bewarder, Karl Bihlmaier, Christian Binner, Jason Bloom, Benjamin Blossom, Somjot Brar, Angela Brown, Robert Burke, Martin N Burke, Michael Butler, William Calhoun, James Campbell, Steve Carroll, Neil Chapman, Craig Chasen, Shi-Chi Cheng, Beth Chia, Nishit Choksi, Jordana Cohen, Niall Connolly, Johanna Contreras, Ronan Cusack, George Dangas, Shukri David, Justin Davies, Juliane Dederer, Matthew Denker, Udo Desch, Matthaios Didangelos, Thomas Dienemann, Kyriakos Dimitriadis, Jean-François Dorval, John Estess, Sarah Fan, Karl Fengler, Lee Ferguson, Marat Fudim, Valentin Fuster, Fidel Garcia, Santiago Garcia, Alex Garton, Carl Gessler, Magdi Ghali, Bharat Gummadi, Amit Gupta, Antonio Gutierrez, Peggy Hardesty, Phillip Hartung, Walter H Haught, Yonghong Haun, Sara Hays, Wolfgang Helmreich, Douglas Hill, Ingrid Hopper, Yu Horiuchi, Satoshi Hoshide, James Howard, Wanda Ikeda, Fued Jan, Rajiv Jauhar, Desmond Jay, James Johnson, Thomas Johnston, Schuyler Jones, Susanne Jung, Theodoros Kalos, Mihar Kanitkar, Dennis Kannenkeril, Alexandros Kasiakogias, Samer Kazziha, Daniel Keene, Jayant Khitha, Hosei Kikushima, Taisei Kobayashi, Kota Komiyama, Takahiro Komori, John Kotter, Antonios Kouparanis, Joshua Krasnow, Saarraangan Kulenthiran, Sarwan Kumar, Philippe L'Allier, Phillip Laney, Lucas Lauder, Marc A Lavoie, Matthias Lerche, Elena Linesky, Nelson Little, Carl Lomboy, Jelena Lucic, Philipp Lurz, Shannon Lynch, Prakash Mansukhani, Katie McDuffie, Brian McGrath, Brent McLaurin, Ashley Meade, Perwaiz Meraj, Dominic Millenaar, Naing Moore, Fumiko Mori, Phillip Munch, James Murphy, Jennifer Murray, Aravinda Nanjundappa, Kai Ninomiya, Yusuke Oba, Tim O'Connor, Yukiyo Ogata, Yukako Ogoyama, Rachel Onsrud, Christian Ott, Bimal Padaliya, Neha Pagidipati, Manesh Patel, Kiritkumar Patel, Emanouela Petteinidou, Wendy Porr, Anjani Rao, Rabia Razi, Christopher Regan, Michael Remetz, David Rizik, Monique Robison, Karl-Philipp Rommel, Liesbeth Rosseel, Marcos Rothstein, Randolph Rough, Jose Saavedra, Souhell Saba, Robert Schwartz, Shaun Selcer, Sayan Sen, Jacqueline Sennott, Ramin Shadman, Samit Shah, Douglas Shemin, Hayato Shimizu, Masahisa Shimpo, Mehdi Shishehbor, Matthew Shun-Shin, Francisco Sierra, Jasvindar Singh, Avneet Singh, Yassir Sirajeldin, Nedaa Skeik, George Soliman, Sarah Statton, Julia Stehli, Susan Steigerwalt, Kristina Striepe, Jason Stuck, Markus Suppan, Laura Svetkey, Ganpat Takker, Kengo Tanabe, Tetsu Tanaka, Daijiro Tomii, Sabino Torre, Jay Traverse, Crystal Tyson, Alejandro Vasquez, Enrique Velasquez, Sreekanth Vemulapalli, Hirotaka Waki, Tony Walton, Yale Wang, Thomas Weber, Bryan Wells, Robert Wilkins, Thomas Wright, Kazuyuki Yahagi, Alan Yeung, Ray Zadegan, Thomas Zeller, Khaled Ziada, Antonios Ziakas, David Zidar

The Lancet 395(10234) 1444-1451 2020年5月2日
The Combination of Non-dipper Heart Rate and High Brain Natriuretic Peptide Predicts Cardiovascular Events: The Japan Morning Surge-Home Blood Pressure (J-HOP) Study

Yukako Ogoyama, Tomoyuki Kabutoya, Satoshi Hoshide, Kazuomi Kario

American Journal of Hypertension 33(5) 430-438 2020年4月29日
【最新の高血圧診療:「高血圧治療ガイドライン2019」後の展開】高血圧の成因、分類、疫学血圧値の分類

成田圭佑, 苅尾七臣

診断と治療 108(4) 435-443 2020年4月
【循環器症候群(第3版)-その他の循環器疾患を含めて-】血圧異常早朝高血圧

成田圭佑, 苅尾七臣

日本臨床別冊(循環器症候群IV) 28-33 2020年3月
What is new in the 2018 Chinese hypertension guideline and the implication for the management of hypertension in Asia?

Ji-Guang Wang, Yook-Chin Chia, Chen-Huan Chen, Sungha Park, Satoshi Hoshide, Naoko Tomitani, Tomoyuki Kabutoya, Jinho Shin, Yuda Turana, Arieska Ann Soenarta, Jam Chin Tay, Peera Buranakitjaroen, Jennifer Nailes, Huynh Van Minh, Saulat Siddique, Jorge Sison, Guru Prasad Sogunuru, Apichard Sukonthasarn, Boon Wee Teo, Narsingh Verma, Yu-Qing Zhang, Tzung-Dau Wang, Kazuomi Kario

Journal of Clinical Hypertension 22(3) 363-368 2020年3月1日
Class effect of xanthine oxidase inhibitors on flow-mediated dilatation in hypertensive patients: A randomized controlled trial

Satoshi Hoshide, Tomoyuki Kabutoya, Hiromi Ueno, Kazuomi Kario

Journal of Clinical Hypertension 22(3) 451-456 2020年3月1日

MISC

224

Burden of Adverse Clinical Outcomes Attributable to Bleeding Complication in Patients with Percutaneous Coronary Intervention

石井正将, 大塚康弘, 池邉壮, 中村太志, 辻田賢一, 藤田英雄, 的場哲哉, 興梠貴英, 大場祐輔, 甲谷友幸, 苅尾七臣, 清末有宏, 水野由子, 中山雅晴, 宮本恵宏, 佐藤寿彦, 永井良三

日本循環器学会学術集会抄録集 88回 PJ122-2 2024年3月
Hypertension facilitates age-related diseases. ~ Is hypertension associated with a wide variety of diseases?~

Masaki Mogi, Yasuhito Ikegawa, Shunsuke Haga, Satoshi Hoshide, Kazuomi Kario

Hypertension Research 2024年
慢性冠動脈疾患患者におけるポリファーマシーの実態と心血管イベントの関連

人見泰弘, 今井靖, 桑原政成, 牧元久樹, 興梠貴英, 相澤健一, 大場祐輔, 甲谷友幸, 苅尾七臣, 的場哲哉, 藤田英雄, 永井良三

日本臨床薬理学会学術総会抄録集(Web) 44th 2023年
Day-to-day blood pressure variability and severity of COVID-19: Is sympathetic overdrive a potential link?

Michiaki Nagai, Takeshi Fujiwara, Kazuomi Kario

Journal of Clinical Hypertension 23(9) 1681-1683 2021年9月1日
Visit-to-visit office blood pressure variability revisited in SPRINT

Michiaki Nagai, Kazuomi Kario

Journal of Clinical Hypertension 23(8) 1526-1528 2021年8月1日