研究者業績

秋元 哲

Akimoto Tetsu

基本情報

所属
自治医科大学 附属病院 透析センター 教授

J-GLOBAL ID
201401071205890648
researchmap会員ID
B000237673

外部リンク

論文

 71
  • 小林 高久, 湯村 和子, 城 謙輔, 小川 弥生, 秋元 哲, 斎藤 修, 武藤 重明, 長田 太助
    日本腎臓学会誌 60(3) 357-357 2018年4月  
  • Takuya Murakami, Tetsu Akimoto, Mari Okada, Erika Hishida, Taro Sugase, Atsushi Miki, Marina Kohara, Hiromichi Yoshizawa, Takahiro Masuda, Takahisa Kobayashi, Osamu Saito, Shigeaki Muto, Daisuke Nagata
    Drug target insights 12 1177392818782899-1177392818782899 2018年  
    A 66-year-old women with no history of renal disease was admitted due to a coma and acute kidney injury with a serum creatinine level of 7.44 mg/dL which were ascribed to valacyclovir neurotoxicity and nephrotoxicity, respectively. She had received valacyclovir at a standard dosage for the treatment of herpes zoster and was finally discharged, having fully returned to her normal baseline mental status with a recovered serum creatinine level of 0.68 mg/dL. We feel that awareness of this pathology remains a challenge for physicians and therefore strongly recommend the further accumulation of experiences similar to our own. Our experience underscores the pitfalls of administering valacyclovir to elderly patients who barely appear to have a favorable renal function. Several concerns regarding the therapeutic management, including blood purification strategies, that emerged in this case are also discussed.
  • Takuya Murakami, Tetsu Akimoto, Tomoyuki Yamazaki, Hiromichi Yoshizawa, Mari Okada, Atsushi Miki, Saki Nakagawa, Ken Ohara, Taro Sugase, Takahiro Masuda, Takahisa Kobayashi, Osamu Saito, Shigeaki Muto, Daisuke Nagata
    Clinical medicine insights. Case reports 11 1179547618785137-1179547618785137 2018年  
    A 28-year-old man was referred and admitted to our hospital due to Escherichia coli O157-mediated hemorrhagic colitis with severe thrombocytopenia. A systemic workup concluded that the patient had acute pancreatitis as well as hemolytic uremic syndrome. The patient was ultimately discharged, with his platelet count having recovered. Our case serves an illustrative example of potentially serious complications of an increasingly recognized public health problem. Systemic studies on this topic are insufficient, and we strongly recommend the further accumulation of more experiences like ours. Several diagnostic and management concerns that emerged in this case are also discussed.
  • Tetsu Akimoto, Tomoyuki Yamazaki, Marina Kohara, Saki Nakagawa, Yoshihiko Kanai, Sayoko Izawa, Hisashi Yamamoto, Eiko Nakazawa, Takahiro Masuda, Takahisa Kobayashi, Osamu Saito, Shigeaki Muto, Eiji Kusano, Daisuke Nagata
    Clinical Medicine Insights: Case Reports 10 1-6 2017年10月13日  査読有り
  • 菱田 英里華, 増田 貴博, 小林 高久, 武田 真一, 秋元 哲, 齋藤 修, 武藤 重明, 長田 太助
    栃木県医学会々誌 47 104-106 2017年6月  
  • Yusuke Igarashi, Tetsu Akimoto, Takahisa Kobayashi, Yoshitaka Iwazu, Takuya Miki, Naoko Otani-Takei, Toshimi Imai, Taro Sugase, Takahiro Masuda, Shin-Ichi Takeda, Shigeaki Muto, Daisuke Nagata
    Clinical Medicine Insights: Case Reports 10 1-5 2017年1月27日  査読有り
  • Mari Okada, Tetsu Akimoto, Mutsumi Kawamata, Toshimi Imai, Erika Hishida, Marina Kohara, Atsushi Miki, Takuya Murakami, Taro Sugase, Takahiro Masuda, Yuko Ono, Yoshihiko Ueda, Osamu Saito, Shigeaki Muto, Daisuke Nagata
    Clinical medicine insights. Case reports 10 1179547617723317-1179547617723317 2017年  
    The association between nephrotic syndrome (NS) and a hypercoagulable state has been demonstrated. Controlling the blood clotting activity may therefore be attractive for patients with nephrosis in terms of thromboembolism prophylaxis. We herein report a 75-year-old woman with minimal change disease who developed pains in the right back, groin, and thigh because of retroperitoneal bleeding during prophylactic anticoagulation with unfractionated heparin. Although this procedure has not been accepted as the standard of care for patients with nephrosis, pharmacologic prophylaxis may already be practiced empirically, as in the present patient. We believe that our experience highlights the pitfalls of such a management in patients with nephrosis, implying the need for a diagnostic strategy for identifying those patients with NS who can benefit from prophylactic anticoagulation. Several concerns that emerged in this case are also discussed.
  • Naoko Otani-Takei, Tetsu Akimoto, Ai Sadatomo, Osamu Saito, Shigeaki Muto, Eiji Kusano, Daisuke Nagata
    Clinical Medicine Insights: Case Reports 9 57-60 2016年8月8日  査読有り
  • 菱田 英里華, 増田 貴博, 山崎 智行, 菅生 太朗, 武島 えり, 五十嵐 祐介, 伊澤 佐世子, 黒澤 明, 南木 浩二, 小林 高久, 武田 真一, 秋元 哲, 八木澤 隆, 齋藤 修, 武藤 重明, 長田 太助
    日本透析医学会雑誌 49(Suppl.1) 475-475 2016年5月  
  • 山崎 智行, 小林 高久, 三木 敦史, 岡田 麻里, 小原 麻里菜, 菱田 英里華, 中川 早紀, 小森 さと子, 吉澤 寛道, 小藤田 篤, 増田 貴博, 秋元 哲, 斉藤 修, 武藤 重明, 長田 太助
    日本透析医学会雑誌 49(Suppl.1) 906-906 2016年5月  
  • Mutsumi Kawamata, Tetsu Akimoto, Taro Sugase, Naoko Otani-Takei, Takuya Miki, Takahiro Masuda, Takahisa Kobayashi, Shin-Ichi Takeda, Shigeaki Muto, Daisuke Nagata
    Clinical Medicine Insights: Case Reports 9 21-24 2016年3月16日  査読有り
  • Takahiro Masuda, Takuya Murakami, Yusuke Igarashi, Kyochika Okabe, Takahisa Kobayashi, Shin-ichi Takeda, Takako Saito, Chuji Sekiguchi, Yasuharu Miyazawa, Tetsu Akimoto, Osamu Saito, Shigeaki Muto, Daisuke Nagata
    INTERNAL MEDICINE 55(19) 2759-2764 2016年  査読有り
  • Sugase Taro, Akimoto Tetsu, Kubo Taro, Imai Toshimi, Otani-Takei Naoko, Miki Takuya, Takeda Shin-ichi, Nukui Akinori, Muto Shigeaki, Morita Tatsuo, Nagata Daisuke
    Internal Medicine 55(17) 2447-2452 2016年  
    <p>Acute kidney injury (AKI) is caused by diverse pathologies, although it may occasionally result from concurrent renal efflux disturbances. We herein describe a case of AKI in a patient complicated by renal cell carcinoma (RCC) with renal vein and inferior vena cava (IVC) involvement. A neoplastic thrombus which disrupted the blood flow in the renal vein appeared to play a role in the rapid decline in the renal function. Such a scenario has rarely been mentioned in the previous literature describing the cases of RCC complicated by AKI. Concerns regarding the diagnostic and therapeutic strategies for RCC are also discussed. </p>
  • 若林 奈津子, 武田 真一, 菅生 太朗, 清水 俊洋, 黒澤 明, 小森 さと子, 伊澤 佐世子, 木村 貴明, 秋元 哲, 齋藤 修, 武藤 重明, 八木澤 隆, 長田 太助
    日本透析医学会雑誌 49(6) 419-423 2016年  
    血液透析のための動静脈シャントは非生理的な血行動態であり, ときに諸臓器への悪影響を生じる. 症例は70歳女性. 糖尿病性腎不全のため20XX年3月に自己血管内シャントを造設, 5月より血液透析が開始されたが, 脱血不良のため8月に人工血管を挿入した. ところが, 透析中に全身の間欠的な痙攣が出現するようになり, 種々画像検査では両側内頸動脈閉塞および左椎骨動脈解離を認めた. 内シャント後に潜在的な盗血を生じ, 血液透析により脳血流障害が助長されたと考え, 直ちに人工血管を閉鎖した. 以降は中心静脈カテーテルを用いて血液透析を行ったところ, 痙攣発作は認めなくなり, シンチグラフィでも脳血流の著明な改善が示された. 内シャントに関連した中枢神経症状の報告は散見されるが, 既報例と異なり, 本症例では過剰血流は認めなかった. 動静脈シャント造設に際しては, 吻合血管のみならず, 全身性の血管病変にも注意を向ける必要性が考えられた.
  • Toshimi Imai, Tetsu Akimoto, Chiharu Ito, Takahiro Masuda, Daisuke Nagata
    Drug Target Insights 9 29-31 2015年11月11日  査読有り
  • Ken Ohara, Tetsu Akimoto, Takuya Miki, Naoko Otani, Taro Sugase, Takahiro Masuda, Takuya Murakami, Toshimi Imai, Shin-Ichi Takeda, Yasuhiro Ando, Shigeaki Muto, Daisuke Nagataa
    Clinical Medicine Insights: Case Reports 8 97-100 2015年9月27日  査読有り
  • 小原 麻里菜, 武田 真一, 清水 俊洋, 今井 麗華, 木村 貴明, 山崎 智行, 駒田 敬則, 佐藤 隆太, 中澤 英子, 森下 義幸, 秋元 哲, 武藤 重明, 八木澤 隆, 長田 太助
    日本透析医学会雑誌 48(Suppl.1) 929-929 2015年5月  
  • Tetsu Akimoto, Chiharu Ito, Atsushi Kotoda, Manabu Ogura, Taro Sugase, Ryuta Sato, Eiji Kusano, Daisuke Nagata
    Clinical Medicine Insights: Case Reports 6 171-175 2013年11月25日  査読有り
  • Ayako Kokuzawa, Yoshiyuki Morishita, Hiromichi Yoshizawa, Kana Iwazu, Takanori Komada, Tetsu Akimoto, Osamu Saito, Takashi Oda, Fumi Takemoto, Yasuhiro Ando, Shigeaki Muto, Wako Yumura, Eiji Kusano
    Internal medicine (Tokyo, Japan) 52(18) 2087-91 2013年  
    We herein report the case of a 17-year-old man who developed an increased plasma creatinine level (11.1 mg/dL) and oliguria with massive proteinuria (27.3 g/day) four weeks after an abraded wound to his right knee. The histology of the renal biopsy specimens showed diffuse endocapillary proliferative glomerulonephritis with the deposition of nephritis-associated plasmin receptor in the glomerulus. A case of acute kidney injury due to nephrotic syndrome caused by acute post-streptococcal glomerulonephritis was diagnosed. His renal function and proteinuria were improved with supportive care, including hemodialysis, without the administration of immunosuppressive agents.
  • Osamu Saito, Takako Saito, Shinji Asakura, Tetsu Akimoto, Makoto Inoue, Yasuhiro Ando, Shigeaki Muto, Eiji Kusano
    International Journal of Endocrinology and Metabolism 10(2) 464-469 2012年4月  
  • Ito Chiharu, Akimoto Tetsu, Nakazawa Eiko, Komori Satoko, Sugase Taro, Chinda Junko, Takahashi Hideaki, Ioka Takashi, Muto Shigeaki, Kusano Eiji
    Internal Medicine 50(1) 47-51 2011年  
    Paraneoplastic nephropathy is a rare complication of malignant disease. We present a case of cervical cancer with biopsy-proven membranous nephropathy and associated nephrotic syndrome. Irradiation to the specific neoplasm site and to the metastatic paraaortic lymph node tissues lead to regression of the nephrotic syndrome without causing severe adverse events. Radiation therapy can be the first choice in the treatment of paraneoplastic nephrotic syndrome if the primary neoplasm is unresectable. Invasiveness of intervention and patient prognosis should be carefully deliberated in the management of the two diseases.<br>

MISC

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共同研究・競争的資金等の研究課題

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