Naoki Usui Masahide Yoshida Yuki Takayanagi Naranbat Nasanbuyan Ayumu Inutsuka Hiroshi Kurosu Hiroaki Mizukami Yoshiyuki Mori Makoto Kuro-O Tatsushi Onaka
Journal of neuroendocrinology e13026 2021年8月
Fibroblast growth factor 21 (FGF21) modulates energy metabolism and neuroendocrine stress responses. FGF21 synthesis is increased after environmental or metabolic challenges. Detailed roles of FGF21 in the control of behavioural disturbances under...
Human gene therapy 32(11-12) 589-598 2021年6月 [査読有り]
Niemann-Pick disease type C1 (NPC1) is a fatal congenital neurodegenerative disorder caused by mutations in the NPC1 gene, which is involved in cholesterol transport in lysosomes. Broad clinical manifestations of NPC1 include liver failure,...
Long-term and mild confinement or isolation in an enclosed environment can occur in situations such as disasters, specific political, economic or social events, nuclear shelters, seabed exploration, polar expeditions, and space travel. To investig...
Journal of neuroendocrinology 33(6) e12980 2021年5月
Social contact reduces stress responses in social animals. Mice have been shown to show allogrooming behaviour toward distressed conspecifics. However, the precise neuronal mechanisms underlying allogrooming behaviour remain unclear. In the presen...
Shota Okabe Yuki Takayanagi Masahide Yoshida Tatsushi Onaka
Scientific reports 11(1) 3805-3805 2021年2月
Gentle touch contributes to affiliative interactions. We investigated the effects of gentle stroking in female rats on the development of affiliative behaviors toward humans and we exploratively examined brain regions in which activity was influen...
Brain and nerve = Shinkei kenkyu no shinpo 75(11) 1205-1209 2023年11月
Resilience is a term that describes the capacity of coping with and recovering from stress and adversity. In terms of the concept of allostasis, resilience is the ability to appropriately regulate allostasis, efficiently terminate the allostatic r...
自治医科大学
医学部