Takeo Nakaya   Seishi Ogawa   Ichiro Manabe   Masami Tanaka   Masashi Sanada   Toshiro Sato   Makoto M. Taketo   Kazuki Nakao   Hans Clevers   Masashi Fukayama   Masahiko Kuroda   Ryozo Nagai   
CANCER RESEARCH 74(10) 2882-2891 2014年5月 [査読有り]
The intestinal epithelium maintains homeostasis by a self-renewal process involving resident stem cells, including Lgr5(+) crypt-base columnar cells, but core mechanisms and their contributions to intestinal cancer are not fully defined. In this s...