Plaque psoriasis (PsO) is a chronic immune-mediated inflammatory disease with skin lesions accompanied by an inflammation-related comorbidity risk. The development of various oral drugs and biologics for PsO has provided increasing systemic treatm...
The Journal of dermatology 50(5) e138-e150 2023年5月
This is the English version of Japanese guidance for the use of oral Janus kinase (JAK) inhibitors (JAK1 and tyrosine kinase 2 [TYK2] inhibitors) in the treatments of psoriasis. Several cytokines, such as interleukin (IL)-6, IL-7, IL-12, IL-21, IL...
Megumi Kishimoto Mayumi Komine Koji Kamiya Junichi Sugai Aya Kuwahara Mamitaro Ohtsuki
The Journal of dermatology 2023年3月
This real-world study at a single academic center retrospectively examined the drug survival of apremilast for patients with psoriasis. Retrospective information was extracted from the medical records of patients with psoriasis treated with apremi...
Narrow band-ultraviolet B (NB-UVB) is an effective treatment for psoriasis. We aim to generate a potential mechanism of NB-UVB through comparing the transcriptomic profile before and after NB-UVB treatment between the peripheral edge of lesional s...
Mayumi Komine Hyunchung Kim Jingbo Yi Yichen Zhong Yoko Sakai Bruce Crawford Katsuyoshi Habiro Yusuke Hikichi Steven R Feldman
The Journal of dermatology 2023年2月
Long-term psoriasis (PsO) management remains challenging. With growing variation in treatment efficacy, cost, and modes of administration, patient preferences for different treatment characteristics are not well understood. A discrete choice exper...
Fujita H Terui T Hayama K Akiyama M Ikeda S Mabuchi T Ozawa A Kanekura T Kurosawa M Komine M Nakajima K Sano S Nemoto O Muto M Imai Y Yamanishi K Aoyama Y Iwatsuki K
自治医科大学
医学部