分子病態治療研究センター抗加齢医学研究部

黒尾誠

研究者氏名	黒尾誠
	クロオマコト
URL
所属	自治医科大学
部署	分子病態治療研究センター　抗加齢医学研究部
職名	教授
J-Global ID	201401055532820666

研究分野

ライフサイエンス / 腎臓内科学 /

論文

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Association of Lower Extremity Muscle Strength and Function with Renal Resistive Index in Individuals with and without Chronic Kidney Disease

Natsumi Nishitani Keisei Kosaki Shoya Mori Masahiro Matsui Takeshi Sugaya Makoto Kuro-o Chie Saito Kunihiro Yamagata Seiji Maeda

Geriatrics 8(6) 118-118 2023年12月

Age-related loss of lower extremity muscle strength is pronounced in individuals with chronic kidney disease (CKD). In contrast, an increase in intrarenal flow pulsatility results in initial age-related changes in renal hemodynamics, leading to th...

Elevated urinary angiotensinogen excretion links central and renal hemodynamic alterations

Keisei Kosaki Jiyeon Park Masahiro Matsui Takeshi Sugaya Makoto Kuro-o Chie Saito Kunihiro Yamagata Seiji Maeda

Scientific Reports 13(1) 2023年7月

Abstract

Inappropriate activation of intrarenal renin–angiotensin system (RAS) may contribute to the pathogenesis of cardio-renal syndrome (CRS). We aimed to examine the cross-sectional associations of urinary angiotensinogen (AGT) excretion, a b...

Correlative light and electron microscopic observation of calcium phosphate particles in a mouse kidney formed under a high-phosphate diet.

Batpurev Battulga Kazuhiro Shiizaki Yutaka Miura Yasuyuki Osanai Reiji Yamazaki Yoshiaki Shinohara Yoshiyuki Kubota Toru Hara Makoto Kuro-O Nobuhiko Ohno

Scientific reports 13(1) 852-852 2023年1月

Calcium phosphate forms particles under excessive urinary excretion of phosphate in the kidney. While the formation of calcium phosphate particles (CaPs) has been implicated in the damage to renal tubular cells and renal dysfunction, clarifying th...

Quantification of Calciprotein Particles (CPPs) in Serum/Plasma Samples Using a Fluorescent Bisphosphonate.

Yutaka Miura Hiroshi Kurosu Makoto Kuro-O

Methods in molecular biology (Clifton, N.J.) 2664 333-341 2023年

Calciprotein particles (CPPs) are mineral-protein complexes containing solid-phase calcium-phosphate and the serum protein fetuin-A. CPPs are dispersed in the blood as colloids. Previous clinical studies revealed that circulating levels of CPPs we...

The effects for inflammatory responses by CPP with different colloidal properties in hemodialysis patients.

Hideyuki Mukai Yutaka Miura Kazuhiko Kotani Atsushi Kotoda Hiroshi Kurosu Toshiyuki Yamada Makoto Kuro-O Yoshitaka Iwazu

Scientific reports 12(1) 21856-21856 2022年12月

Calciprotein particles (CPPs) are colloids composed of solid-phase calcium-phosphate and serum protein fetuin-A. CPPs form a polydispersed system with different particle size and density. CPPs with specific physical properties can induce calcifica...