Originally, apomorphine was a broad-spectrum dopamine agonist with an affinity for all subtypes of the Dopamine D1 receptor to the D5 receptor. We previously identified apomorphine as a potential therapeutic agent for mitochondrial diseases by scr...
Ayaka Ohashi Daisuke Matsubara Yoshitaka Mizobe Tadahiro Mitani Marika Ono Miki Nozawa Makoto Ito Toshihiro Tajima Hitoshi Osaka
Journal of burn care & research : official publication of the American Burn Association 2024年2月
Thermal airway injuries, usually accompanied by facial burns, require emergency management. We encountered a pediatric case of a late airway-scalding injury without any initial signs of scalding on the face or inside the oral cavity. A 16-month-ol...
Menkes disease is an X-linked disorder of copper metabolism caused by mutations in the ATP7A gene, and female carriers are usually asymptomatic. We describe a 7-month-old female patient with severe intellectual disability, epilepsy, and low levels...
Pediatrics international : official journal of the Japan Pediatric Society 66(1) e15742 2024年
BACKGROUND: Premature children are known to be at a high risk of developing behavioral problems. This study examined the effectiveness of parent-child interaction therapy (PCIT) in reducing behavioral problems in young children born premature. MET...
Epileptic disorders : international epilepsy journal with videotape 22(2) 214-218 2020年4月
Ring chromosome 20 syndrome is an epileptic and neurodevelopmental encephalopathy that occurs in children, characterised by a triad of refractory frontal lobe seizures, recurrent non-convulsive status epilepticus and frontal lobe-dominant paroxysm...
自治医科大学
医学部