Hepatitis E virus (HEV) genotypes 3 and 4 are zoonotic strains that are primarily transmitted through the consumption of undercooked pork or game meat. They also cause asymptomatic infections, acute hepatitis, acute-on-chronic liver failure, chron...
Tatsuo Kanda Reina Sasaki‐Tanaka Koji Ishii Ryosuke Suzuki Jun Inoue Atsunori Tsuchiya Shingo Nakamoto Ryuzo Abe Keiichi Fujiwara Osamu Yokosuka Tian‐Cheng Li Satoshi Kunita Hiroshi Yotsuyanagi Hiroaki Okamoto
Hepatology Research 2023年10月
Abstract
In 2018, there was a hepatitis A outbreak in Japan, and HAV infection is considered a sexually transmitted disease. In general, patients with hepatitis A should be given attention, and this disease should be prevented more than ever. The...
Previously, we developed an infectious hepatitis E virus (HEV) harboring the nanoKAZ gene in the hypervariable region of the open reading frame 1 (ORF1) of the HEV3b (JE03-1760F/P10) genome and demonstrated the usefulness for screening anti-HEV dr...
Yuichi Yoshida Asami Ito Hisashi Eto Akiko Suzuki Tamami Abe Kei Endo Keisuke Kakisaka Takayoshi Oikawa Hidekatsu Kuroda Akio Miyasaka Takayuki Matsumoto Masaharu Takahashi Hiroaki Okamoto
Hepatology research : the official journal of the Japan Society of Hepatology 2023年8月
AIM: Hepatitis E virus (HEV) causes subclinical or acute self-limiting hepatitis. We surveyed the current seroprevalence and incidence of HEV infection among the general population in Iwate Prefecture, Japan, where the endemic infection is presume...
Hepatitis E virus (HEV) causes acute or chronic hepatitis in humans. Pigs are the primary reservoir for zoonotic HEV genotypes 3 and 4 worldwide. This study investigated the infection dynamics and genomic mutations of HEV in domestic pigs on a far...
Putu Prathiwi Primadharsini Shigeo Nagashima Hiroaki Okamoto
VIRUSES-BASEL 13(5) 2021年5月
Hepatitis E virus (HEV) is the leading cause of acute hepatitis worldwide. While the transmission in developing countries is dominated by fecal-oral route via drinking contaminated water, the zoonotic transmission is the major route of HEV infecti...
Putu Prathiwi Primadharsini Shigeo Nagashima Hiroaki Okamoto
VIRUSES-BASEL 11(5) 2019年5月
Hepatitis E virus (HEV) is a single-stranded positive-sense RNA virus. HEV can cause both acute and chronic hepatitis, with the latter usually occurring in immunocompromised patients. Modes of transmission range from the classic fecal-oral route o...
自治医科大学
医学部