During the development of analgesic tolerance to morphine, the V1b vasopressin receptor has been proposed to bind to β-arrestin 2 and the µ-opioid receptor to enable their interaction. However, direct evidence of such a high-order complex is lacki...
Histochemistry and cell biology 155(4) 503-512 2021年4月
Hypertension leads to structural remodeling of cerebral blood vessels, which has been implicated in the pathophysiology of cerebrovascular diseases. The remodeling and progression of arteriolosclerosis under hypertension involve fibrosis along wit...
Kiyomi Mashima Morio Azuma Ken Fujiwara Takashi Inagaki Iekuni Oh Takashi Ikeda Kento Umino Hirofumi Nakano Kaoru Morita Kazuya Sato Daisuke Minakata Ryoko Yamasaki Masahiro Ashizawa Chihiro Yamamoto Shin-Ichiro Fujiwara Kaoru Hatano Ken Ohmine Kazuo Muroi Nobuhiko Ohno Yoshinobu Kanda
Acta histochemica et cytochemica 53(3) 43-53 2020年6月 [査読有り]
Leukemias are refractory hematopoietic malignancies, for which the development of new therapeutic agents requires in vivo studies using tumor-bearing mouse models. Although several organs are commonly examined in such studies to evaluate the disea...
自治医科大学
医学部