研究者氏名	藤原慎一郎
	フジワラシンイチロウ
URL	http://kaken.nii.ac.jp/d/r/20438667.ja.html
所属	自治医科大学
部署	輸血・細胞移植部
職名	教授
J-Global ID	201401051157883889

研究キーワード

造血幹細胞移植 ,輸血 ,抗原発現 ,悪性リンパ腫

研究分野

ライフサイエンス / 血液、腫瘍内科学 /
その他 / その他 / 病態検査学

経歴

2020年

現在

自治医科大学附属病院輸血・細胞移植部教授

2012年

2020年

自治医科大学内科学講座血液学部門講師

2008年

2012年

自治医科大学内科学講座血液学部門助教

論文

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Impact of stem cell selection between bone marrow and peripheral blood stem cells for unrelated hematopoietic stem cell transplantation for hematologic malignancies: on behalf of the Donor/Source Working Group of the Japanese Society for Transplantation and Cellular Therapy.

Hiromi Hayashi Makoto Iwasaki Hideki Nakasone Reo Tanoshima Masashi Shimabukuro Wataru Takeda Tetsuya Nishida Shinichi Kako Shin-Ichiro Fujiwara Yuta Katayama Masashi Sawa Kentaro Serizawa Ken-Ichi Matsuoka Naoyuki Uchida Takashi Ikeda Hiroyuki Ohigashi Kentaro Fukushima Moeko Hino Yoshinobu Kanda Takahiro Fukuda Yoshiko Atsuta Junya Kanda

Cytotherapy 2023年12月

BACKGROUND AIMS: This study aimed to comprehensively assess the impact of stem cell selection between bone marrow (BM) and peripheral blood (PB) in unrelated hematopoietic stem cell transplantation (HSCT) for hematological malignancies. Our object...

Cost-effectiveness of anti-BCMA chimeric antigen receptor T cell therapy in relapsed/ refractory multiple myeloma.

Chihiro Yamamoto Daisuke Minakata Daizo Yokoyama Shuka Furuki Atsuto Noguchi Shunsuke Koyama Takashi Oyama Rui Murahashi Hirotomo Nakashima Takashi Ikeda Shin-Ichiro Kawaguchi Kazuki Hyodo Yumiko Toda Shoko Ito Takashi Nagayama Kento Umino Kaoru Morita Masahiro Ashizawa Masuzu Ueda Kaoru Hatano Kazuya Sato Ken Ohmine Shin-Ichiro Fujiwara Yoshinobu Kanda

Transplantation and cellular therapy 2023年10月

BACKGROUND: Despite its promising outcome, anti-BCMA CAR-T is the most expensive myeloma treatment that has ever been developed, and its cost-effectiveness is an important issue. OBJECTIVE: This study aimed to assess the cost-effectiveness of anti...

Early reversal of the lymphocyte-to-monocyte ratio after allogeneic-hematopoietic stem cell transplantation is associated with reduced relapse and improved prognosis.

Takashi Nagayama Shin-Ichiro Fujiwara Ryutaro Tominaga Daizo Yokoyama Atsuto Noguchi Shuka Furuki Takashi Oyama Shunsuke Koyama Rui Murahashi Hirotomo Nakashima Takashi Ikeda Kazuki Hyodo Shin-Ichiro Kawaguchi Yumiko Toda Kento Umino Kaoru Morita Masahiro Ashizawa Chihiro Yamamoto Kaoru Hatano Kazuya Sato Ken Ohmine Yoshinobu Kanda

Clinical transplantation e15116 2023年8月

BACKGROUND: The early recovery of lymphocyte and monocyte cells is associated with a favorable prognosis after allogeneic stem cell transplantation (allo-HSCT); however, it is not clear whether the balance of lymphocyte and monocyte recovery affec...

Clinical significance of late CMV disease in adult patients who underwent allogeneic stem cell transplant.

Hiroaki Shimizu Yuho Najima Shinichi Kako Masatsugu Tanaka Shin-Ichiro Fujiwara Takehiko Mori Kensuke Usuki Moritaka Gotoh Maki Hagihara Nobuhiro Tsukada Makoto Oniduka Satoru Takada Emiko Sakaida Shin Fujisawa Masahiro Onoda Nobuyuki Aotsuka Shingo Yano Kazuteru Ohashi Satoshi Takahashi Shinichiro Okamoto Yoshinobu Kanda

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2023年8月

INTRODUCTION: Late cytomegalovirus (CMV) disease, which was defined as CMV disease occurring >100 days post-transplant, remains an important complication among allogeneic stem cell transplant recipients, even now that the prophylactic strategy usi...

Antibody-mediated pathogenesis of chronic GVHD through DBY/HLA class II complexes and induction of a GVL effect.

Kento Umino Kaoru Morita Takashi Ikeda Shin-Ichiro Kawaguchi Takashi Nagayama Shoko Ito Daisuke Minakata Masahiro Ashizawa Chihiro Yamamoto Kaoru Hatano Kazuya Sato Ken Ohmine Shin-Ichiro Fujiwara Shun-Ichi Kimura Shinichi Kako Noriko Doki Yukiyasu Ozawa Yasuo Mori Tetsuya Eto Nobuhiro Hiramoto Hirohisa Nakamae Junya Kanda Tatsuo Ichinohe Yoshiko Atsuta Hideki Nakasone Satoko Morishima Yoshinobu Kanda

Blood 2023年6月

Chronic graft-versus-host disease (cGVHD) is a multiorgan syndrome with clinical features resembling those of autoimmune diseases. Thus, understanding commonalities in the pathophysiology of cGVHD and autoimmune diseases, such as the presence of d...

MISC

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急性リンパ性白血病に対するtisagenlecleucel製造結果 -日本輸血・細胞治療学会CAR-T療法タスクフォースによる研究-

城友泰城友泰平安山知子富澤大輔吉原哲吉原哲加畑馨藤原実名美奥山美樹柴徳生藤井敬子梅澤佳央山崎理絵武田航葉名尻良福島健太郎三村尚也池本純子岩木啓太米谷昇藤原慎一郎李政樹長村登紀子田野崎隆二新井康之新井康之

臨床血液 64(5) 2023年

同種移植後インフルエンザウイルス感染症 KSGCT多施設共同二次調査研究(Influenza virus infection after hematopoietic stem cell transplantation: a KSGCT multicenter survey)

原田介斗鬼塚真仁森毅彦清水啓明瀬尾幸子青墳信之竹田勇輔関谷紀貴楠田待子藤原慎一郎白岩佐和子鐘野勝洋新谷直樹金森平和桃木真美子高田覚迎純一増田真一三谷絹子堺田惠美子富川武樹高橋聡臼杵憲祐神田善伸

日本血液学会学術集会 83回 OS3-5 2021年9月

Dimethyl Fumarate Ameliorates Graft-Versus-Host Disease By Negatively Regulating Aerobic Glycolysis in Alloreactive T-Cells

Kiyomi Mashima Kazuya Sato Norihito Takayama Junko Izawa Takashi Ikeda Kento Umino Hirofumi Nakano Daisuke Minakata Kaoru Morita Chihiro Yamamoto Masahiro Ashizawa Kaoru Hatano Iekuni Oh Ken Ohmine Shin-ichiro Fujiwara Yoshinobu Kanda

BLOOD 136 2020年11月

造血器疾患をもつ大量赤血球輸血患者に対する鉄キレート療法の現状

横濱章彦奥山美樹上田恭典伊藤真澄藤原慎一郎長井一浩荒川仁香牧田雅典宮崎浩二池田和彦紀野修一田中朝志長谷川雄一藤野恵三牧野茂義松本真弓竹下明裕室井一男日本輸血・細胞治療学会臨床研究推進委員会

日本輸血細胞治療学会誌 66(2) 370-370 2020年5月 [査読有り]

Ph陽性白血病に対する血液再発予防目的TKI中止の検証

仲宗根秀樹仲宗根秀樹神田善伸神田善伸森毅彦森毅彦鬼塚真仁鬼塚真仁佐倉徹佐倉徹藤原慎一郎藤原慎一郎堺田惠美子堺田惠美子横田朗横田朗青墳信之青墳信之萩原真紀萩原真紀塚田信弘塚田信弘八田善弘八田善弘臼杵憲祐臼杵憲祐中世古玲子中世古玲子後藤守孝後藤守孝藤澤信藤澤信矢野真吾矢野真吾高橋聡高橋聡金森平和金森平和岡本真一郎岡本真一郎

日本造血細胞移植学会総会プログラム・抄録集 42nd 2020年