研究者業績

藤井 裕之

フジイ ヒロユキ  (Hiroyuki Fujii)

基本情報

所属
自治医科大学 医学部 放射線医学講座 講師

J-GLOBAL ID
201401075661474791
researchmap会員ID
B000238487

受賞

 4

論文

 56
  • Kohei Hamamoto, Ryoma Kobayashi, Emiko Chiba, Naoki Kunitomo, Soichiro Kojima, Hiroyuki Fujii, Mitsuru Matsuki, Kazuma Rifu, Homare Ito, Mineyuki Tojo, Harushi Mori
    BJR case reports 12(2) uaag005 2026年3月  
    Pancreatic arteriovenous malformation (PAVM) is a rare vascular anomaly of the gastrointestinal tract, and the coexistence of a pseudoaneurysm is exceptionally uncommon. This report details a case of pseudoaneurysm associated with a massive PAVM that was successfully managed with endovascular therapy. A 67-year-old female patient with a massive PAVM presented with acute back pain. Contrast-enhanced computed tomography revealed a pseudoaneurysm in the pancreatic head accompanied by a surrounding haematoma. Transcatheter arterial embolisation (TAE) was selected as the minimally invasive treatment and the pseudoaneurysm was visualised on angiography. However, identifying the culprit artery was challenging due to the extensive vascular network of the PAVM. Following modification of the local haemodynamics using coil embolisation, the culprit artery became detectable, allowing successful embolisation of the pseudoaneurysm using N-butyl cyanoacrylate (NBCA). This case report highlights the clinical utility of NBCA embolisation combined with flow modification for managing a pseudoaneurysm associated with a massive PAVM, which represents an exceptionally rare vascular anomaly.
  • Tomohiro Kikuchi, Kohei Yamamoto, Yosuke Yamagishi, Toshiaki Akashi, Shouhei Hanaoka, Takeharu Yoshikawa, Hiroyuki Fujii, Harushi Mori, Hisaki Makimoto, Takahide Kohro
    2026年2月3日  
    Abstract Background Large-scale CT-based reference standards for abdominal organ volume, incorporating age, sex, and body size, are limited. Purpose To establish sex- and age-specific reference distributions for major abdominal organ volumes on non-contrast abdominopelvic CT in a nationwide Japanese cohort to provide a foundation for automated clinical assessment and dose optimization. Materials and Methods In this retrospective, multicenter study, using the Japan Medical Image Database, we identified all non-contrast abdominopelvic CT examinations performed in 2024. Unique adults with available data on age, sex, height, and weight were included in this study. The final sample comprised 49,764 examinations (26,456 men and 23,308 women) conducted at nine institutions. Automated segmentation (TotalSegmentator v2.10.0) was used to produce organ volumes, excluding hollow viscera. The sex-specific 10th, 25th, 50th, 75th, and 90th percentiles were calculated. Age–volume relationships of body surface area (BSA)-normalized volumes (mL/m 2 ) were modeled using natural cubic splines (four degrees of freedom) separately by sex. Results Median (mL) male vs female volumes were as follows: liver, 1194.7 vs 1024.0; pancreas, 63.6 vs 52.2; spleen, 118.1 vs 95.1; kidneys (total), 268.3 vs 221.2; adrenals (total), 6.6 vs 4.2; iliopsoas (total), 483.4 vs 317.7; prostate, 24.9 (men only). Age–volume relationships of BSA-normalized volumes showed convex patterns for the liver, pancreas, and kidneys in both sexes and for male adrenal glands; lower values in older age groups for the spleen and iliopsoas in both sexes; and higher values in older age groups for the prostate and female adrenal glands. Conclusion This nationwide Japanese CT cohort provides sex- and age-resolved volumetric reference standards. These standards enable objective identification of abnormalities, support personalized medicine, and facilitate automated AI-based reporting to reduce radiologist workload and optimize radiation dose protocols. Key Results Median volumes (men vs women, mL): liver 1195/1024; pancreas 64/52; spleen 118/95; kidneys 268/221; adrenals 6.6/4.2; iliopsoas 483/318; prostate 25. Body surface area–normalized age–volume relationships were convex for liver, pancreas, and kidneys in both sexes and for male adrenal glands. Spleen and iliopsoas declined monotonically with age in both sexes, whereas prostate and female adrenal glands increased monotonically.
  • Noriko Ito, Mitsuru Matsuki, Akihiro Nakamata, Sota Masuoka, Emiko Chiba, Kohei Hamamoto, Hiroyuki Fujii, Harushi Mori
    Radiology case reports 21(2) 599-603 2026年2月  査読有り
    Acetabular fractures are usually caused by high-energy trauma, and seizure-induced cases resulting from strong muscle contractions are extremely rare. We report the case of a 90-year-old man with osteoporosis who incurred a nontraumatic acetabular fracture during a seizure. Computed tomography revealed an internal iliac artery injury, which was promptly treated with transcatheter arterial embolization. As such vascular injuries, though rare, require early diagnosis and treatment, radiologists must be aware of the associated imaging findings and management, particularly in cognitively impaired patients.
  • Hiroyuki Fujii, Tomohiro Kikuchi, Nana Fujii, Emiko Chiba, Sota Masuoka, Akihiro Nakamata, Kohei Hamamoto, Mitsuru Matsuki, Harushi Mori
    AJNR. American journal of neuroradiology 47(1) 142-150 2026年1月5日  査読有り筆頭著者責任著者
    BACKGROUND AND PURPOSE: Bell's palsy (BP) is the most common cause of facial nerve (FN) palsy. This study aimed to investigate the diagnostic ability of the 3D Double-Echo Steady-State with Water Excitation (3D-DESS-WE) sequence to visualize pathological changes in the FN of BP patients. MATERIALS AND METHODS: We retrospectively analyzed 30 BP patients who underwent 3T MRI including 3D-DESS-WE within 30 days of onset and 60 sex-and age±2-matched controls. Qualitative evaluation of FN signal intensity (SIFN) and thickness (THFN) was performed using a 3-point scale. Quantitative metrics included SIFN and THFN measurements and affected-to-unaffected ratios (SRA/U and TRA/U) in the BP group, and right-to-left ratios in controls. Interobserver agreement, group comparisons, correlations with clinical severity (Yanagihara score), and diagnostic performance were assessed. In a subset of 17 matched pairs, the diagnostic performance of contrast-enhanced T1WI (CE-T1WI) was assessed, and its agreement with 3D-DESS-WE-based qualitative assessment was evaluated. RESULTS: Qualitative scores for SIFN and THFN were significantly higher in the BP group than in controls (P < .001), with high interobserver agreement (κ = 0.810, 0.788, respectively). When dichotomized (score 0 vs. 1-2), qualitative assessments showed good diagnostic performance with sensitivity and specificity of 0.87 and 0.82 for SIFN, and 0.90 and 0.80 for THFN, respectively. Neither qualitative score correlated significantly with clinical severity. Agreement between 3D-DESS-WE-based and CE-T1WI-based qualitative assessments was substantial to almost perfect (κ = 0.766-0.882). In quantitative analysis, both SIFN and THFN were significantly higher on the affected side in the BP group (P < .001), whereas no significant lateral differences were observed in controls. Although SIFN, THFN, and SRA/U did not correlate significantly with clinical severity, TRA/U was significantly inversely correlated with the Yanagihara score (r = -0.413, P = .02), which corresponds to a positive correlation with clinical severity. The Yanagihara score was the only independent predictor for TRA/U in multiple regression analysis (β = -0.425, P = .04). ROC analysis showed high diagnostic performance: AUC = 0.908 for SRA/U and 0.927 for TRA/U. CONCLUSIONS: 3D-DESS-WE may be a valuable tool for the routine clinical assessment of BP. ABBREVIATIONS: 3D-DESS-WE=3D Double-Echo Steady-State with Water Excitation; 3D-PSIF=3D reversed fast imaging in steady-state free precession.
  • Emiko Chiba, Kohei Hamamoto, Mamoru Arakawa, Satoshi Uesugi, Soichiro Kojima, Ryoma Kobayashi, Tatsuya Ogawa, Hiroyuki Fujii, Mitsuru Matsuki, Harushi Mori
    Annals of vascular diseases 19(1) 2026年  
    We present a rare case of type II endoleak (T2EL) from an atypical mediastinal artery following total arch replacement with a frozen elephant trunk (FET) for chronic aortic dissection. A 63-year-old male with a history of multiple thoracic aortic surgeries, including FET, developed enlargement of an aortic arch aneurysm on follow-up. Computed tomography and diagnostic angiography revealed a T2EL due to a newly developed mediastinal collateral artery arising from the left subclavian artery feeding the sac. Selective transcatheter embolization with N-butyl-2-cyanoacrylate successfully eliminated the endoleak. Recognizing such atypical T2EL sources is crucial for managing post-FET aneurysm expansion.

MISC

 84

書籍等出版物

 6

共同研究・競争的資金等の研究課題

 1