仲宗根 秀樹

An autopsy case of T-cell lymphoma complicated with hemophagocytic syndrome (HPS) is reported. A 60-year-old woman presenting with fever and jaundice was transferred to our hospital. On admission, she showed bicytopenia, severe liver dysfunction and coagulopathy. She subsequently developed pancytopenia. At first, she was suspected of having aplastic anemia. Methylpredonisolone pulse therapy was therefore initiated, and the leukopenia improved. But she later developed leukopenia again, and died of septic shock. At autopsy, proliferation of histiocytes with hemophagocytosis was observed in the reticuloendothelial system. Moreover, T-cell lymphoma was observed. Hence diagnosis of T-cell lymphoma with HPS was made pathologically.