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三瀬 名丹 ミセ ナタン

所属部署名環境予防医学講座
職名講師ホームページURL

プロフィール

研究キーワード

    DNAメチル化, 無機ヒ素, マウス初期発生, エピジェネティクス

研究分野

  • 基礎生物学 / 遺伝・ゲノム動態
  • 生物科学 / 分子生物学
  • 生物科学 / 発生生物学

所属学協会

  • 日本衛生学会
  • 日本分子生物学会
所属学協会を全て表示する
所属学協会閉じる
  • 日本衛生学会
  • 日本分子生物学会

学位

  • 地球環境科学博士

研究活動

論文

  • Cadmium, arsenic and lead accumulation in rice grains produced in Senegal river valley
    Ndong Moussa, Mise Nathan, Okunaga Masaki, Kayama Fujio
    Fundamental Toxicological Sciences 5(2) 87-91 2018年
  • External lead contamination of women's nails by surma in Pakistan: Is the biomarker reliable?
    Ikegami A, Takagi M, Fatmi Z, Kobayashi Y, Ohtsu M, Cui X, Mise N, Mizuno A, Sahito A, Khoso A, Kayama F
    Environmental pollution (Barking, Essex : 1987) 218 723-727 2016年11月
  • Factors associated with occupation changes after pregnancy/delivery: result from Japan Environment & Children's pilot study.
    Suga R, Tsuji M, Tanaka R, Shibata E, Tanaka M, Senju A, Araki S, Morokuma S, Sanefuji M, Oda M, Mise N, Baba Y, Hayama-Terada M, Kusuhara K, Mitsubuchi H, Katoh T, Kawamoto T
    BMC women's health 18(1) 86 2018年06月
  • LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation.
    Chow JC, Ciaudo C, Fazzari MJ, Mise N, Servant N, Glass JL, Attreed M, Avner P, Wutz A, Barillot E, Greally JM, Voinnet O, Heard E
    Cell 166(3) 782 2016年07月
  • MicroRNAs as Potential Mediators for Cigarette Smoking Induced Atherosclerosis.
    Yokoyama Y, Mise N, Suzuki Y, Tada-Oikawa S, Izuoka K, Zhang L, Zong C, Takai A, Yamada Y, Ichihara S
    International journal of molecular sciences 19(4) 2018年04月
  • Heavy metal exposure, in combination with physical activity and aging, is related with oxidative stress in Japanese women from a rural agricultural community.
    Cui X, Ohtsu M, Mise N, Ikegami A, Mizuno A, Sakamoto T, Ogawa M, Machida M, Kayama F
    SpringerPlus 5(1) 885 2016年06月
  • Regional differences in infant 25-Hydroxyvitamin D: Pilot study of the Japan Environment and Children's Study.
    Ayabe T, Yamamoto-Hanada K, Mezawa H, Konishi M, Ishitsuka K, Saito M, Fukami M, Michikawa T, Yamazaki S, Senju A, Kusuhara K, Kawamoto T, Sanefuji M, Kato K, Oda M, Mitsubuchi H, Katoh T, Monden Y, Mise N, Kayama F, Saito H, Ohya Y
    Pediatrics international : official journal of the Japan Pediatric Society 60(1) 30-34 2018年01月
  • Lead Exposure Assessment among Pregnant Women, Newborns, and Children: Case Study from Karachi, Pakistan.
    Fatmi Z, Sahito A, Ikegami A, Mizuno A, Cui X, Mise N, Takagi M, Kobayashi Y, Kayama F
    International journal of environmental research and public health 14(4) 2017年04月
  • The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
    Kobayashi M, Usui-Kawanishi F, Karasawa T, Kimura H, Watanabe S, Mise N, Kayama F, Kasahara T, Hasebe N, Takahashi M
    PloS one 12(5) e0176676 2017年
  • Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan.
    Kayama, F. Fatmi, Z. Ikegami, A. Mizuno, A. Ohtsu, M. Mise, N. Cui, X. Ogawa, M. Sakamoto, T. Nakagi, Y. Yoshida, T. Sahito, A. Naeem, S. Ghias, K. Zuberi, H. Tariq, K. Kobayashi, Y. Nohara, K.
    Rev. Environ. Health 31(1) 33-35 2016年
論文等(論文)を全て表示する
論文等(論文)閉じる
  • Cadmium, arsenic and lead accumulation in rice grains produced in Senegal river valley
    Ndong Moussa, Mise Nathan, Okunaga Masaki, Kayama Fujio
    Fundamental Toxicological Sciences 5(2) 87-91 2018年
  • External lead contamination of women's nails by surma in Pakistan: Is the biomarker reliable?
    Ikegami A, Takagi M, Fatmi Z, Kobayashi Y, Ohtsu M, Cui X, Mise N, Mizuno A, Sahito A, Khoso A, Kayama F
    Environmental pollution (Barking, Essex : 1987) 218 723-727 2016年11月
  • Factors associated with occupation changes after pregnancy/delivery: result from Japan Environment & Children's pilot study.
    Suga R, Tsuji M, Tanaka R, Shibata E, Tanaka M, Senju A, Araki S, Morokuma S, Sanefuji M, Oda M, Mise N, Baba Y, Hayama-Terada M, Kusuhara K, Mitsubuchi H, Katoh T, Kawamoto T
    BMC women's health 18(1) 86 2018年06月
  • LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation.
    Chow JC, Ciaudo C, Fazzari MJ, Mise N, Servant N, Glass JL, Attreed M, Avner P, Wutz A, Barillot E, Greally JM, Voinnet O, Heard E
    Cell 166(3) 782 2016年07月
  • MicroRNAs as Potential Mediators for Cigarette Smoking Induced Atherosclerosis.
    Yokoyama Y, Mise N, Suzuki Y, Tada-Oikawa S, Izuoka K, Zhang L, Zong C, Takai A, Yamada Y, Ichihara S
    International journal of molecular sciences 19(4) 2018年04月
  • Heavy metal exposure, in combination with physical activity and aging, is related with oxidative stress in Japanese women from a rural agricultural community.
    Cui X, Ohtsu M, Mise N, Ikegami A, Mizuno A, Sakamoto T, Ogawa M, Machida M, Kayama F
    SpringerPlus 5(1) 885 2016年06月
  • Regional differences in infant 25-Hydroxyvitamin D: Pilot study of the Japan Environment and Children's Study.
    Ayabe T, Yamamoto-Hanada K, Mezawa H, Konishi M, Ishitsuka K, Saito M, Fukami M, Michikawa T, Yamazaki S, Senju A, Kusuhara K, Kawamoto T, Sanefuji M, Kato K, Oda M, Mitsubuchi H, Katoh T, Monden Y, Mise N, Kayama F, Saito H, Ohya Y
    Pediatrics international : official journal of the Japan Pediatric Society 60(1) 30-34 2018年01月
  • Lead Exposure Assessment among Pregnant Women, Newborns, and Children: Case Study from Karachi, Pakistan.
    Fatmi Z, Sahito A, Ikegami A, Mizuno A, Cui X, Mise N, Takagi M, Kobayashi Y, Kayama F
    International journal of environmental research and public health 14(4) 2017年04月
  • The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
    Kobayashi M, Usui-Kawanishi F, Karasawa T, Kimura H, Watanabe S, Mise N, Kayama F, Kasahara T, Hasebe N, Takahashi M
    PloS one 12(5) e0176676 2017年
  • Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan.
    Kayama, F. Fatmi, Z. Ikegami, A. Mizuno, A. Ohtsu, M. Mise, N. Cui, X. Ogawa, M. Sakamoto, T. Nakagi, Y. Yoshida, T. Sahito, A. Naeem, S. Ghias, K. Zuberi, H. Tariq, K. Kobayashi, Y. Nohara, K.
    Rev. Environ. Health 31(1) 33-35 2016年
  • Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits.
    Kohara K, Pignatelli M, Rivest AJ, Jung HY, Kitamura T, Suh J, Frank D, Kajikawa K, Mise N, Obata Y, Wickersham IR, Tonegawa S
    Nature neuroscience 17(2) 269-279 2014年02月
  • Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells.
    Yukawa M, Akiyama T, Franke V, Mise N, Isagawa T, Suzuki Y, Suzuki MG, Vlahovicek K, Abe K, Aburatani H, Aoki F
    PloS one 9(3) e92689 2014年03月
  • Large, male germ cell-specific hypomethylated DNA domains with unique genomic and epigenomic features on the mouse X chromosome.
    Ikeda R, Shiura H, Numata K, Sugimoto M, Kondo M, Mise N, Suzuki M, Greally JM, Abe K
    DNA research : an international journal for rapid publication of reports on genes and genomes 20(6) 549-565 2013年12月
  • Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a.
    Kuroki S, Matoba S, Akiyoshi M, Matsumura Y, Miyachi H, Mise N, Abe K, Ogura A, Wilhelm D, Koopman P, Nozaki M, Kanai Y, Shinkai Y, Tachibana M
    Science (New York, N.Y.) 341(6150) 1106-1109 2013年09月
  • Development of a general-purpose method for cell purification using Cre/loxP-mediated recombination.
    Kuroki S, Akiyoshi M, Ideguchi K, Kitano S, Miyachi H, Hirose M, Mise N, Abe K, Ogura A, Tachibana M
    Genesis (New York, N.Y. : 2000) 53(6) 387-393 2015年06月
  • Max is a repressor of germ cell-related gene expression in mouse embryonic stem cells.
    Maeda I, Okamura D, Tokitake Y, Ikeda M, Kawaguchi H, Mise N, Abe K, Noce T, Okuda A, Matsui Y
    Nature communications 4 1754 2013年
  • Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells.
    Okamura D, Maeda I, Taniguchi H, Tokitake Y, Ikeda M, Ozato K, Mise N, Abe K, Noce T, Izpisua Belmonte JC, Matsui Y
    Genes & development 26(22) 2477-2482 2012年11月
  • Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse.
    Hoki Y, Ikeda R, Mise N, Sakata Y, Ohhata T, Sasaki H, Abe K, Sado T
    Development (Cambridge, England) 138(13) 2649-2659 2011年07月
  • Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes.
    Imamura M, Aoi T, Tokumasu A, Mise N, Abe K, Yamanaka S, Noce T
    Molecular reproduction and development 77(9) 802-811 2010年09月
  • The X-linked imprinted gene family Fthl17 shows predominantly female expression following the two-cell stage in mouse embryos.
    Kobayashi S, Fujihara Y, Mise N, Kaseda K, Abe K, Ishino F, Okabe M
    Nucleic acids research 38(11) 3672-3681 2010年06月
  • LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation.
    Chow JC, Ciaudo C, Fazzari MJ, Mise N, Servant N, Glass JL, Attreed M, Avner P, Wutz A, Barillot E, Greally JM, Voinnet O, Heard E
    Cell 141(6) 956-969 2010年06月
  • A high-speed congenic strategy using first-wave male germ cells.
    Ogonuki N, Inoue K, Hirose M, Miura I, Mochida K, Sato T, Mise N, Mekada K, Yoshiki A, Abe K, Kurihara H, Wakana S, Ogura A
    PloS one 4(3) e4943 2009年
  • Natural antisense transcripts are co-expressed with sense mRNAs in synaptoneurosomes of adult mouse forebrain.
    Smalheiser NR, Lugli G, Torvik VI, Mise N, Ikeda R, Abe K
    Neuroscience research 62(4) 236-239 2008年12月
  • Differences and similarities in the developmental status of embryo-derived stem cells and primordial germ cells revealed by global expression profiling.
    Mise N, Fuchikami T, Sugimoto M, Kobayakawa S, Ike F, Ogawa T, Tada T, Kanaya S, Noce T, Abe K
    Genes to cells : devoted to molecular & cellular mechanisms 13(8) 863-877 2008年08月
  • Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages.
    Kobayashi S, Isotani A, Mise N, Yamamoto M, Fujihara Y, Kaseda K, Nakanishi T, Ikawa M, Hamada H, Abe K, Okabe M
    Current biology : CB 16(2) 166-172 2006年01月
  • Disclosing hidden transcripts: mouse natural sense-antisense transcripts tend to be poly(A) negative and nuclear localized.
    Kiyosawa H, Mise N, Iwase S, Hayashizaki Y, Abe K
    Genome research 15(4) 463-474 2005年04月
  • Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells.
    Mise-Omata S, Obata Y, Iwase S, Mise N, Doi TS
    Biochemical and biophysical research communications 328(4) 1034-1042 2005年03月
  • Birth of mice produced by germ cell nuclear transfer.
    Miki H, Inoue K, Kohda T, Honda A, Ogonuki N, Yuzuriha M, Mise N, Matsui Y, Baba T, Abe K, Ishino F, Ogura A
    Genesis (New York, N.Y. : 2000) 41(2) 81-86 2005年02月
  • BAC modification using a RecA expressing shuttle vector system.
    Mise N, Avner P
    Methods in molecular biology (Clifton, N.J.) 256 77-87 2004年
  • Translocation breakpoint possibly predisposes to nonrandom X-chromosome inactivation in mouse embryos bearing Searle's T(X;16)16H translocation.
    Ogura, H. Takada, S. Mise, N. Sugimoto, M. Tan, S. S. Takagi, N.
    Cytogenet Cell Genet. 80 173-178 1998年
  • Activation of the inactive X chromosome induced by cell fusion between a murine EC and female somatic cell accompanies reproducible changes in the methylation pattern of the Xist gene.
    Mise, N. Sado, T. Tada, M. Takada, S. Takagi, N.
    Exp Cell Res. 223(2) 193-202 1996年03月
  • Dorsoventral polarization and formation of dorsal axial structures in Xenopus laevis: analyses using UV irradiation of the full-grown oocyte and after fertilization.
    Mise, N. Wakahara, M.
    Int J Dev Biol. 38(3) 447-453 1994年09月
  • Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method
    Hayashizaki, Y. Shibata, H. Hirotsune, S. Sugino, H. Okazaki, Y. Sasaki, N. Hirose, K. Imoto, H. Okuizumi, H. Muramatsu, M. et al.,
    Nature Genetics 6(1) 33-40 1994年01月
  • Molecular cloning of antisense transcripts of the mouse Xist gene
    Mise, N. Wakahara, M.
    Biochem Biophys Res Commun 258(3) 537-541 1999年05月

MISC

  • 刷り込み型遺伝子発現におけるDNAメチル化の影響 : ES細胞を用いた解析
    三瀬 名丹
    臨床環境医学 : 日本臨床環境医学会会誌 = Japanese journal of clinical ecology 19(2) 72-78 2010年12月
論文等(その他)を全て表示する
論文等(その他)閉じる
  • 刷り込み型遺伝子発現におけるDNAメチル化の影響 : ES細胞を用いた解析
    三瀬 名丹
    臨床環境医学 : 日本臨床環境医学会会誌 = Japanese journal of clinical ecology 19(2) 72-78 2010年12月

外部的資金

  • ヒ素の胎児期暴露がエピゲノムに与える影響の疫学的及び実験的解析
    科学研究費補助金:基盤研究(C)
    研究期間 :2015年 - 2018年 代表者 : 三瀬 名丹
  • 体細分化と生殖細胞分化におけるゲノム刷り込みの成立と消去
    科学研究費補助金:基盤研究(C)
    研究期間 :2009年 - 2012年 代表者 : 三瀬 名丹
  • ゲノム再プログラム化を支配するゲノムワイドな遺伝子発現調節機構の解析
    科学研究費補助金:特定領域研究
    研究期間 :2004年 - 2005年 代表者 : 三瀬 名丹
  • マウス始原生殖細胞発生過程におけるX染色体再活生化の解析
    科学研究費補助金:若手研究(B)
    研究期間 :2004年 - 2007年 代表者 : 三瀬 名丹
外部資金採択状況を全て表示する
外部資金採択状況閉じる
  • ヒ素の胎児期暴露がエピゲノムに与える影響の疫学的及び実験的解析
    科学研究費補助金:基盤研究(C)
    研究期間 :2015年 - 2018年 代表者 : 三瀬 名丹
  • 体細分化と生殖細胞分化におけるゲノム刷り込みの成立と消去
    科学研究費補助金:基盤研究(C)
    研究期間 :2009年 - 2012年 代表者 : 三瀬 名丹
  • ゲノム再プログラム化を支配するゲノムワイドな遺伝子発現調節機構の解析
    科学研究費補助金:特定領域研究
    研究期間 :2004年 - 2005年 代表者 : 三瀬 名丹
  • マウス始原生殖細胞発生過程におけるX染色体再活生化の解析
    科学研究費補助金:若手研究(B)
    研究期間 :2004年 - 2007年 代表者 : 三瀬 名丹


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