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長嶋 茂雄 ナガシマ シゲオ

所属部署名感染・免疫学講座ウイルス学部門
職名講師ホームページURLhttp://kaken.nii.ac.jp/d/r/60433116.ja.html

プロフィール

研究キーワード

    Tsg101, E型肝炎ウイルス, ESCRT機構, 放出, MVB経路, 粒子形成, 分子疫学, B群, 消毒済, ロタウイルス, MRSA, 生理学, 消毒剤, 浸淫状況, PVL, 新種, プロテオーム, スタフィロコアグラーゼ, 黄色ブドウ球菌, 成人, 熱帯地域, 感染培養系, アジア, 多剤排出蛋白, 下痢症, 感染性cDNAクローン, ゲノム変異, 下痢, PSAPモチーフ, 腸球菌

研究分野

  • 基礎医学 / ウイルス学
  • 社会医学 / 衛生学

経歴

  • 2013年
    自治医科大学 医学部(講師)

学位

  • 医学博士

研究活動

論文

  • Rat hepatitis E virus derived from wild rats (Rattus rattus) propagates efficiently in human hepatoma cell lines.
    Jirintai S, Tanggis, Mulyanto, Suparyatmo JB, Takahashi M, Kobayashi T, Nagashima S, Nishizawa T, Okamoto H
    Virus research 185 92-102 2014年06月
  • The membrane on the surface of hepatitis E virus particles is derived from the intracellular membrane and contains trans-Golgi network protein 2.
    Nagashima S, Takahashi M, Jirintai S, Tanggis, Kobayashi T, Nishizawa T, Okamoto H
    Archives of virology 159 979-991 2014年05月
  • Molecular characterization of a novel hepatitis E virus (HEV) strain obtained from a wild boar in Japan that is highly divergent from the previously recognized HEV strains.
    Takahashi M, Nishizawa T, Nagashima S, Jirintai S, Kawakami M, Sonoda Y, Suzuki T, Yamamoto S, Shigemoto K, Ashida K, Sato Y, Okamoto H
    Virus research 180 59-69 2014年02月
  • Marked genomic heterogeneity of rat hepatitis E virus strains in Indonesia demonstrated on a full-length genome analysis.
    Mulyanto, Suparyatmo JB, Andayani IG, Khalid, Takahashi M, Ohnishi H, Jirintai S, Nagashima S, Nishizawa T, Okamoto H
    Virus research 179 102-112 2014年01月
  • Characterization of sporadic acute hepatitis E and comparison of hepatitis E virus genomes in acute hepatitis patients and pig liver sold as food in Mie, Japan.
    Okano H, Takahashi M, Isono Y, Tanaka H, Nakano T, Oya Y, Sugimoto K, Ito K, Ohmori S, Maegawa T, Kobayashi M, Nagashima S, Nishizawa T, Okamoto H
    Hepatology research : the official journal of the Japan Society of Hepatology 2013年08月
  • High genomic similarity between European type hepatitis E virus subgenotype 3e strains isolated from an acute hepatitis patient and a wild boar in Mie, Japan.
    Okano H, Nakano T, Sugimoto K, Takahashi K, Nagashima S, Takahashi M, Arai M, Okamoto H
    Hepatology research : the official journal of the Japan Society of Hepatology 2013年05月
  • Frequent detection and characterization of hepatitis E virus variants in wild rats (Rattus rattus) in Indonesia.
    Mulyanto, Depamede SN, Sriasih M, Takahashi M, Nagashima S, Jirintai S, Nishizawa T, Okamoto H
    Archives of virology 158 87-96 2013年01月
  • Molecular analysis of hepatitis E virus from farm rabbits in Inner Mongolia, China and its successful propagation in A549 and PLC/PRF/5 cells.
    Jirintai S, Jinshan, Tanggis, Manglai D, Mulyanto, Takahashi M, Nagashima S, Kobayashi T, Nishizawa T, Okamoto H
    Virus research 170 126-137 2012年12月
  • A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains: demonstration of HEV infectivity of porcine liver sold as food.
    Takahashi H, Tanaka T, Jirintai S, Nagashima S, Takahashi M, Nishizawa T, Mizuo H, Yazaki Y, Okamoto H
    Archives of virology 157 235-246 2012年02月
  • Identification of four novel subgenotypes (C13-C16) and two inter-genotypic recombinants (C12/G and C13/B3) of hepatitis B virus in Papua province, Indonesia.
    Mulyanto, Pancawardani P, Depamede SN, Wahyono A, Jirintai S, Nagashima S, Takahashi M, Nishizawa T, Okamoto H
    Virus research 163 129-140 2012年01月
論文等(論文)を全て表示する
論文等(論文)閉じる
  • Rat hepatitis E virus derived from wild rats (Rattus rattus) propagates efficiently in human hepatoma cell lines.
    Jirintai S, Tanggis, Mulyanto, Suparyatmo JB, Takahashi M, Kobayashi T, Nagashima S, Nishizawa T, Okamoto H
    Virus research 185 92-102 2014年06月
  • The membrane on the surface of hepatitis E virus particles is derived from the intracellular membrane and contains trans-Golgi network protein 2.
    Nagashima S, Takahashi M, Jirintai S, Tanggis, Kobayashi T, Nishizawa T, Okamoto H
    Archives of virology 159 979-991 2014年05月
  • Molecular characterization of a novel hepatitis E virus (HEV) strain obtained from a wild boar in Japan that is highly divergent from the previously recognized HEV strains.
    Takahashi M, Nishizawa T, Nagashima S, Jirintai S, Kawakami M, Sonoda Y, Suzuki T, Yamamoto S, Shigemoto K, Ashida K, Sato Y, Okamoto H
    Virus research 180 59-69 2014年02月
  • Marked genomic heterogeneity of rat hepatitis E virus strains in Indonesia demonstrated on a full-length genome analysis.
    Mulyanto, Suparyatmo JB, Andayani IG, Khalid, Takahashi M, Ohnishi H, Jirintai S, Nagashima S, Nishizawa T, Okamoto H
    Virus research 179 102-112 2014年01月
  • Characterization of sporadic acute hepatitis E and comparison of hepatitis E virus genomes in acute hepatitis patients and pig liver sold as food in Mie, Japan.
    Okano H, Takahashi M, Isono Y, Tanaka H, Nakano T, Oya Y, Sugimoto K, Ito K, Ohmori S, Maegawa T, Kobayashi M, Nagashima S, Nishizawa T, Okamoto H
    Hepatology research : the official journal of the Japan Society of Hepatology 2013年08月
  • High genomic similarity between European type hepatitis E virus subgenotype 3e strains isolated from an acute hepatitis patient and a wild boar in Mie, Japan.
    Okano H, Nakano T, Sugimoto K, Takahashi K, Nagashima S, Takahashi M, Arai M, Okamoto H
    Hepatology research : the official journal of the Japan Society of Hepatology 2013年05月
  • Frequent detection and characterization of hepatitis E virus variants in wild rats (Rattus rattus) in Indonesia.
    Mulyanto, Depamede SN, Sriasih M, Takahashi M, Nagashima S, Jirintai S, Nishizawa T, Okamoto H
    Archives of virology 158 87-96 2013年01月
  • Molecular analysis of hepatitis E virus from farm rabbits in Inner Mongolia, China and its successful propagation in A549 and PLC/PRF/5 cells.
    Jirintai S, Jinshan, Tanggis, Manglai D, Mulyanto, Takahashi M, Nagashima S, Kobayashi T, Nishizawa T, Okamoto H
    Virus research 170 126-137 2012年12月
  • A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains: demonstration of HEV infectivity of porcine liver sold as food.
    Takahashi H, Tanaka T, Jirintai S, Nagashima S, Takahashi M, Nishizawa T, Mizuo H, Yazaki Y, Okamoto H
    Archives of virology 157 235-246 2012年02月
  • Identification of four novel subgenotypes (C13-C16) and two inter-genotypic recombinants (C12/G and C13/B3) of hepatitis B virus in Papua province, Indonesia.
    Mulyanto, Pancawardani P, Depamede SN, Wahyono A, Jirintai S, Nagashima S, Takahashi M, Nishizawa T, Okamoto H
    Virus research 163 129-140 2012年01月

MISC

  • 配偶者間及び同性愛者間で認められたB型急性肝炎例を感染源とするB型肝炎ウイルスA2型株感染
    相川 達也, 津田 文男, 上野 ちさと, 間宮 孝, 杉山 弘明, 添田 敦子, 池澤 和人, 長嶋 茂雄, 高橋 雅春, 岡本 宏明
    肝臓 54(6) 373-380 2013年
論文等(その他)を全て表示する
論文等(その他)閉じる
  • 配偶者間及び同性愛者間で認められたB型急性肝炎例を感染源とするB型肝炎ウイルスA2型株感染
    相川 達也, 津田 文男, 上野 ちさと, 間宮 孝, 杉山 弘明, 添田 敦子, 池澤 和人, 長嶋 茂雄, 高橋 雅春, 岡本 宏明
    肝臓 54(6) 373-380 2013年


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