市原　佐保子(環境予防医学講座) | 自治医科大学教員業績データベース

NF‑κB inhibitor DHMEQ inhibits titanium dioxide nanoparticle‑induced interleukin‑1β production: Inhibition of the PM2.5‑induced inflammation model.
Fukatsu H, Koide N, Tada-Oikawa S, Izuoka K, Ikegami A, Ichihara S, Ukaji T, Morita N, Naiki Y, Komatsu T, Umezawa K
Molecular medicine reports 2018年10月
DOI
Proteomic Profiling of Exosomal Proteins for Blood-based Biomarkers in Parkinson's Disease.
Kitamura Y, Kojima M, Kurosawa T, Sasaki R, Ichihara S, Hiraku Y, Tomimoto H, Murata M, Oikawa S
Neuroscience 392 121-128 2018年09月
DOI
Pulmonary hypofunction due to calcium carbonate nanomaterial exposure in occupational workers: a cross-sectional study.
Li G, Liang L, Yang J, Zeng L, Xie Z, Zhong Y, Ruan X, Dong M, Yang Z, Lai G, Huang W, Yang A, Chen J, Wu B, Xu H, Meng D, Hu S, Xia L, Yang X, Li L, Ichihara S, Ichihara G, Huang H, Huang Z
Nanotoxicology 12(6) 571-585 2018年08月
DOI
Exposure of Mice to 1,2-Dichloropropane Induces CYP450-Dependent Proliferation and Apoptosis of Cholangiocytes.
Zhang X, Zong C, Zhang L, Garner E, Sugie S, Huang C, Wu W, Chang J, Sakurai T, Kato M, Ichihara S, Kumagai S, Ichihara G
Toxicological sciences : an official journal of the Society of Toxicology 162(2) 559-569 2018年04月
DOI
MicroRNAs as Potential Mediators for Cigarette Smoking Induced Atherosclerosis.
Yokoyama Y, Mise N, Suzuki Y, Tada-Oikawa S, Izuoka K, Zhang L, Zong C, Takai A, Yamada Y, Ichihara S
International journal of molecular sciences 19(4) 2018年04月
DOI
Proteomics analysis identified peroxiredoxin 2 involved in early-phase left ventricular impairment in hamsters with cardiomyopathy.
Kuzuya K, Ichihara S, Suzuki Y, Inoue C, Ichihara G, Kurimoto S, Oikawa S
PloS one 13(2) e0192624 2018年
DOI
Involvement of oxidative modification of proteins related to ATP synthesis in the left ventricles of hamsters with cardiomyopathy.
Ichihara S, Suzuki Y, Chang J, Kuzuya K, Inoue C, Kitamura Y, Oikawa S
Scientific reports 7(1) 9243 2017年08月
DOI
Effect of 4-week inhalation exposure to 1-bromopropane on blood pressure in rats.
Huang F, Ichihara S, Yamada Y, Banu S, Ichihara G
Journal of applied toxicology : JAT 37(3) 331-338 2017年03月
DOI
Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer's disease.
Kitamura Y, Usami R, Ichihara S, Kida H, Satoh M, Tomimoto H, Murata M, Oikawa S
Neurological research 39(3) 231-238 2017年03月
DOI
Significant association of RNF213 p.R4810K, a moyamoya susceptibility variant, with coronary artery disease.
Morimoto T, Mineharu Y, Ono K, Nakatochi M, Ichihara S, Kabata R, Takagi Y, Cao Y, Zhao L, Kobayashi H, Harada KH, Takenaka K, Funaki T, Yokota M, Matsubara T, Yamamoto K, Izawa H, Kimura T, Miyamoto S, Koizumi A
PloS one 12(4) e0175649 2017年
DOI
Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease.
Nakatochi M, Ichihara S, Yamamoto K, Naruse K, Yokota S, Asano H, Matsubara T, Yokota M
Clinical epigenetics 9 54 2017年
DOI
Role of cytochrome P450s in the male reproductive toxicity of 1-bromopropane.
Zong C, Zhang X, Huang C, Chang J, Garner CE, Sakurai T, Kato M, Ichihara S, Ichihara G
Toxicology research 5(6) 1522-1529 2016年11月
DOI
Single- and double-walled carbon nanotubes enhance atherosclerogenesis by promoting monocyte adhesion to endothelial cells and endothelial progenitor cell dysfunction.
Suzuki Y, Tada-Oikawa S, Hayashi Y, Izuoka K, Kataoka M, Ichikawa S, Wu W, Zong C, Ichihara G, Ichihara S
Particle and fibre toxicology 13(1) 54 2016年10月
DOI
Preliminary characterization of a murine model for 1-bromopropane neurotoxicity: Role of cytochrome P450.
Zong C, Garner CE, Huang C, Zhang X, Zhang L, Chang J, Toyokuni S, Ito H, Kato M, Sakurai T, Ichihara S, Ichihara G
Toxicology letters 258 249-258 2016年09月
DOI
Titanium Dioxide Particle Type and Concentration Influence the Inflammatory Response in Caco-2 Cells.
Tada-Oikawa S, Ichihara G, Fukatsu H, Shimanuki Y, Tanaka N, Watanabe E, Suzuki Y, Murakami M, Izuoka K, Chang J, Wu W, Yamada Y, Ichihara S
International journal of molecular sciences 17(4) 576 2016年04月
DOI
Epigenome-wide association study suggests that SNPs in the promoter region of RETN influence plasma resistin level via effects on DNA methylation at neighbouring sites.
Nakatochi M, Ichihara S, Yamamoto K, Ohnaka K, Kato Y, Yokota S, Hirashiki A, Naruse K, Asano H, Izawa H, Matsubara T, Yokota M
Diabetologia 58(12) 2781-2790 2015年12月
DOI
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, Kelly TN, Saleheen D, Lehne B, Leach IM, Drong AW, Abbott J, Wahl S, Tan ST, Scott WR, Campanella G, Chadeau-Hyam M, Afzal U, Ahluwalia TS, Bonder MJ, Chen P, Dehghan A, Edwards TL, Esko T, Go MJ, Harris SE, Hartiala J, Kasela S, Kasturiratne A, Khor CC, Kleber ME, Li H, Yu Mok Z, Nakatochi M, Sapari NS, Saxena R, Stewart AFR, Stolk L, Tabara Y, Teh AL, Wu Y, Wu JY, Zhang Y, Aits I, Da Silva Couto Alves A, Das S, Dorajoo R, Hopewell JC, Kim YK, Koivula RW, Luan J, Lyytikäinen LP, Nguyen QN, Pereira MA, Postmus I, Raitakari OT, Scannell Bryan M, Scott RA, Sorice R, Tragante V, Traglia M, White J, Yamamoto K, Zhang Y, Adair LS, Ahmed A, Akiyama K, Asif R, Aung T, Barroso I, Bjonnes A, Braun TR, Cai H, Chang LC, Chen CH, Cheng CY, Chong YS, Collins R, Courtney R, Davies G, Delgado G, Do LD, Doevendans PA, Gansevoort RT, Gao YT, Grammer TB, Grarup N, Grewal J, Gu D, Wander GS, Hartikainen AL, Hazen SL, He J, Heng CK, Hixson JE, Hofman A, Hsu C, Huang W, Husemoen LLN, Hwang JY, Ichihara S, Igase M, Isono M, Justesen JM, Katsuya T, Kibriya MG, Kim YJ, Kishimoto M, Koh WP, Kohara K, Kumari M, Kwek K, Lee NR, Lee J, Liao J, Lieb W, Liewald DCM, Matsubara T, Matsushita Y, Meitinger T, Mihailov E, Milani L, Mills R, Mononen N, Müller-Nurasyid M, Nabika T, Nakashima E, Ng HK, Nikus K, Nutile T, Ohkubo T, Ohnaka K, Parish S, Paternoster L, Peng H, Peters A, Pham ST, Pinidiyapathirage MJ, Rahman M, Rakugi H, Rolandsson O, Ann Rozario M, Ruggiero D, Sala CF, Sarju R, Shimokawa K, Snieder H, Sparsø T, Spiering W, Starr JM, Stott DJ, Stram DO, Sugiyama T, Szymczak S, Tang WHW, Tong L, Trompet S, Turjanmaa V, Ueshima H, Uitterlinden AG, Umemura S, Vaarasmaki M, van Dam RM, van Gilst WH, van Veldhuisen DJ, Viikari JS, Waldenberger M, Wang Y, Wang A, Wilson R, Wong TY, Xiang YB, Yamaguchi S, Ye X, Young RD, Young TL, Yuan JM, Zhou X, Asselbergs FW, Ciullo M, Clarke R, Deloukas P, Franke A, Franks PW, Franks S, Friedlander Y, Gross MD, Guo Z, Hansen T, Jarvelin MR, Jørgensen T, Jukema JW, Kähönen M, Kajio H, Kivimaki M, Lee JY, Lehtimäki T, Linneberg A, Miki T, Pedersen O, Samani NJ, Sørensen TIA, Takayanagi R, Toniolo D, BIOS-consortium., CARDIo GRAMplusCD., LifeLines Cohort Study., InterAct Consortium., Ahsan H, Allayee H, Chen YT, Danesh J, Deary IJ, Franco OH, Franke L, Heijman BT, Holbrook JD, Isaacs A, Kim BJ, Lin X, Liu J, März W, Metspalu A, Mohlke KL, Sanghera DK, Shu XO, van Meurs JBJ, Vithana E, Wickremasinghe AR, Wijmenga C, Wolffenbuttel BHW, Yokota M, Zheng W, Zhu D, Vineis P, Kyrtopoulos SA, Kleinjans JCS, McCarthy MI, Soong R, Gieger C, Scott J, Teo YY, He J, Elliott P, Tai ES, van der Harst P, Kooner JS, Chambers JC
Nature genetics 47(11) 1282-1293 2015年11月
DOI
Copper Oxide Nanoparticles Reduce Vasculogenesis in Transgenic Zebrafish Through Down-Regulation of Vascular Endothelial Growth Factor Expression and Induction of Apoptosis.
Chang J, Ichihara G, Shimada Y, Tada-Oikawa S, Kuroyanagi J, Zhang B, Suzuki Y, Sehsah R, Kato M, Tanaka T, Ichihara S
Journal of nanoscience and nanotechnology 15(3) 2140-2147 2015年03月
DOI
Hippocampal phosphoproteomics of F344 rats exposed to 1-bromopropane.
Huang Z, Ichihara S, Oikawa S, Chang J, Zhang L, Hu S, Huang H, Ichihara G
Toxicology and applied pharmacology 282(2) 151-160 2015年01月
DOI
[Editor's Note].
Ichihara S
Nihon eiseigaku zasshi. Japanese journal of hygiene 70(1) 97 2015年
DOI
Zn(II) released from zinc oxide nano/micro particles suppresses vasculogenesis in human endothelial colony-forming cells.
Tada-Oikawa S, Ichihara G, Suzuki Y, Izuoka K, Wu W, Yamada Y, Mishima T, Ichihara S
Toxicology reports 2 692-701 2015年
DOI
A trial to find appropriate animal models of dichloropropane-induced cholangiocarcinoma based on the hepatic distribution of glutathione S-transferases.
Zhang L, Zong C, Ichihara S, Naito H, Toyokuni S, Kumagai S, Ichihara G
Journal of occupational health 57(6) 548-554 2015年
DOI
Synergistic effect of bolus exposure to zinc oxide nanoparticles on bleomycin-induced secretion of pro-fibrotic cytokines without lasting fibrotic changes in murine lungs.
Wu W, Ichihara G, Hashimoto N, Hasegawa Y, Hayashi Y, Tada-Oikawa S, Suzuki Y, Chang J, Kato M, D'Alessandro-Gabazza CN, Gabazza EC, Ichihara S
International journal of molecular sciences 16(1) 660-676 2014年12月
DOI
Zinc oxide nanoparticles induce migration and adhesion of monocytes to endothelial cells and accelerate foam cell formation.
Suzuki Y, Tada-Oikawa S, Ichihara G, Yabata M, Izuoka K, Suzuki M, Sakai K, Ichihara S
Toxicology and applied pharmacology 278(1) 16-25 2014年07月
DOI
Non-equilibrium atmospheric pressure plasmas modulate cell cycle-related gene expressions in melanocytic tumors of RET-transgenic mice.
Yajima I, Iida M, Kumasaka MY, Omata Y, Ohgami N, Chang J, Ichihara S, Hori M, Kato M
Experimental dermatology 23(6) 424-425 2014年06月
DOI
The effects of non-thermal atmospheric pressure plasma irradiation on expression levels of matrix metalloproteinases in benign melanocytic tumors in RET-transgenic mice.
Iida M, Yajima I, Ohgami N, Tamura H, Takeda K, Ichihara S, Hori M, Kato M
European journal of dermatology : EJD 24(3) 392-394 2014年05月
DOI
Association of a polymorphism of BTN2A1 with dyslipidemia in community-dwelling individuals.
Horibe H, Ueyama C, Fujimaki T, Oguri M, Kato K, Ichihara S, Yamada Y
Molecular medicine reports 9(3) 808-812 2014年03月
DOI
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.
Wu Y, Gao H, Li H, Tabara Y, Nakatochi M, Chiu YF, Park EJ, Wen W, Adair LS, Borja JB, Cai Q, Chang YC, Chen P, Croteau-Chonka DC, Fogarty MP, Gan W, He CT, Hsiung CA, Hwu CM, Ichihara S, Igase M, Jo J, Kato N, Kawamoto R, Kuzawa CW, Lee JJ, Liu J, Lu L, McDade TW, Osawa H, Sheu WH, Teo Y, Vadlamudi S, Van Dam RM, Wang Y, Xiang YB, Yamamoto K, Ye X, Young TL, Zheng W, Zhu J, Shu XO, Shin C, Jee SH, Chuang LM, Miki T, Yokota M, Lin X, Mohlke KL, Tai ES
Human molecular genetics 23(4) 1108-1119 2014年02月
DOI
High-phosphorus/zinc-free diet aggravates hypertension and cardiac dysfunction in a rat model of the metabolic syndrome.
Suzuki Y, Mitsushima S, Kato A, Yamaguchi T, Ichihara S
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 23(1) 43-49 2014年01月
DOI
Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat.
Chang J, Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Aoki C, Yamada Y, Ichihara G, Kato M, Ichihara S
Diabetology & metabolic syndrome 6(1) 8 2014年01月
DOI
Dispersion method for safety research on manufactured nanomaterials.
Wu W, Ichihara G, Suzuki Y, Izuoka K, Oikawa-Tada S, Chang J, Sakai K, Miyazawa K, Porter D, Castranova V, Kawaguchi M, Ichihara S
Industrial health 52(1) 54-65 2014年
DOI
Identification of a glutamic acid repeat polymorphism of ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by genome-wide linkage analysis.
Ichihara S, Yamamoto K, Asano H, Nakatochi M, Sukegawa M, Ichihara G, Izawa H, Hirashiki A, Takatsu F, Umeda H, Iwase M, Inagaki H, Hirayama H, Sone T, Nishigaki K, Minatoguchi S, Cho MC, Jang Y, Kim HS, Park JE, Tada-Oikawa S, Kitajima H, Matsubara T, Sunagawa K, Shimokawa H, Kimura A, Lee JY, Murohara T, Inoue I, Yokota M
Circulation. Cardiovascular genetics 6(6) 569-578 2013年12月
DOI
Rats with metabolic syndrome resist the protective effects of N-acetyl l-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet.
Suzuki Y, Ichihara G, Sahabudeen SM, Kato A, Yamaguchi T, Imanaka-Yoshida K, Yoshida T, Yamada Y, Ichihara S
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 65(7-8) 1173-1182 2013年11月
DOI
Association of a polymorphism of BTN2A1 with chronic kidney disease in community-dwelling individuals.
Oguri M, Fujimaki T, Horibe H, Kato K, Ichihara S, Yamada Y
Biomedical reports 1(6) 868-872 2013年11月
DOI
Serial changes in adipocytokines and cardiac function in a rat model of the metabolic syndrome.
Yamaguchi T, Kitamori K, Ichihara G, Suzuki Y, Ochiai M, Yamada Y, Tada-Oikawa S, Tsuchikura S, Yamori Y, Ichihara S
Clinical and experimental pharmacology & physiology 40(7) 443-448 2013年07月
DOI
Identification of chromosome 3q28 and ALPK1 as susceptibility loci for chronic kidney disease in Japanese individuals by a genome-wide association study.
Yamada Y, Nishida T, Ichihara S, Kato K, Fujimaki T, Oguri M, Horibe H, Yoshida T, Watanabe S, Satoh K, Aoyagi Y, Fukuda M, Sawabe M
Journal of medical genetics 50(6) 410-418 2013年06月
DOI
The pathological roles of environmental and redox stresses in cardiovascular diseases.
Ichihara S
Environmental health and preventive medicine 18(3) 177-184 2013年05月
DOI
Effects of sub-acute and sub-chronic inhalation of 1-bromopropane on neurogenesis in adult rats.
Zhang L, Nagai T, Yamada K, Ibi D, Ichihara S, Subramanian K, Huang Z, Mohideen SS, Naito H, Ichihara G
Toxicology 304 76-82 2013年02月
DOI
Effects of exposure to 1-bromopropane on astrocytes and oligodendrocytes in rat brain.
Mohideen SS, Ichihara S, Subramanian K, Huang Z, Naito H, Kitoh J, Ichihara G
Journal of occupational health 55(1) 29-38 2013年
DOI
Exposure to 1-bromopropane induces microglial changes and oxidative stress in the rat cerebellum.
Subramanian K, Mohideen SS, Suzumura A, Asai N, Murakumo Y, Takahashi M, Jin S, Zhang L, Huang Z, Ichihara S, Kitoh J, Ichihara G
Toxicology 302(1) 18-24 2012年12月
DOI
Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat.
Chang J, Oikawa S, Ichihara G, Nanpei Y, Hotta Y, Yamada Y, Tada-Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Ichihara S
Nutrition & metabolism 9(1) 87 2012年09月
DOI
Proteomic identification of carbonylated proteins in F344 rat hippocampus after 1-bromopropane exposure.
Huang Z, Ichihara S, Oikawa S, Chang J, Zhang L, Subramanian K, Mohideen SS, Ichihara G
Toxicology and applied pharmacology 263(1) 44-52 2012年08月
DOI
Proteomic analysis of hippocampal proteins of F344 rats exposed to 1-bromopropane.
Huang Z, Ichihara S, Oikawa S, Chang J, Zhang L, Takahashi M, Subramanian K, Mohideen SS, Wang Y, Ichihara G
Toxicology and applied pharmacology 257(1) 93-101 2011年11月
DOI
Dose-dependent neurologic abnormalities in workers exposed to 1-bromopropane: authors' response.
Ichihara G, Wang H, Zhang L, Wakai K, Li W, Ding X, Shibata E, Zhou Z, Wang Q, Li J, Ichihara S, Takeuchi Y
Journal of occupational and environmental medicine 53(10) 1095-1098 2011年10月
DOI
Exposure to 1-bromopropane causes degeneration of noradrenergic axons in the rat brain.
Mohideen SS, Ichihara G, Ichihara S, Nakamura S
Toxicology 285(1-2) 67-71 2011年07月
DOI
The ratio of adiponectin to homeostasis model assessment of insulin resistance is a powerful index of each component of metabolic syndrome in an aged Japanese population: results from the KING Study.
Nakatochi M, Miyata S, Tanimura D, Izawa H, Asano H, Murase Y, Kato R, Ichihara S, Naruse K, Matsubara T, Honda H, Yokota M
Diabetes research and clinical practice 92(3) e61-5 2011年06月
DOI
Relation of a common variant of the adiponectin gene to serum adiponectin concentration and metabolic traits in an aged Japanese population.
Tanimura D, Shibata R, Izawa H, Hirashiki A, Asano H, Murase Y, Miyata S, Nakatochi M, Ouchi N, Ichihara S, Yasui K, Yoshida T, Naruse K, Matsubara T, Yokota M
European journal of human genetics : EJHG 19(3) 262-269 2011年03月
DOI
Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations.
Yamada Y, Nishida T, Ichihara S, Sawabe M, Fuku N, Nishigaki Y, Aoyagi Y, Tanaka M, Fujiwara Y, Yoshida H, Shinkai S, Satoh K, Kato K, Fujimaki T, Yokoi K, Oguri M, Yoshida T, Watanabe S, Nozawa Y, Hasegawa A, Kojima T, Han BG, Ahn Y, Lee M, Shin DJ, Lee JH, Jang Y
Atherosclerosis 215(1) 145-152 2011年03月
DOI
Pleural plaque profiles on the chest radiographs and CT scans of asbestos-exposed Japanese construction workers.
Elshazley M, Shibata E, Hisanaga N, Ichihara G, Ewis AA, Kamijima M, Ichihara S, Sakai K, Sato M, Kondo M, Hasegawa Y
Industrial health 49(5) 626-633 2011年
DOI
Ablation of the transcription factor Nrf2 promotes ischemia-induced neovascularization by enhancing the inflammatory response.
Ichihara S, Yamada Y, Liu F, Murohara T, Itoh K, Yamamoto M, Ichihara G
Arteriosclerosis, thrombosis, and vascular biology 30(8) 1553-1561 2010年08月
DOI
Dose-dependent neurologic abnormalities in workers exposed to 1-bromopropane.
Li W, Shibata E, Zhou Z, Ichihara S, Wang H, Wang Q, Li J, Zhang L, Wakai K, Takeuchi Y, Ding X, Ichihara G
Journal of occupational and environmental medicine 52(8) 769-777 2010年08月
DOI
Increased susceptibility of Nrf2-null mice to 1-bromopropane-induced hepatotoxicity.
Liu F, Ichihara S, Valentine WM, Itoh K, Yamamoto M, Sheik Mohideen S, Kitoh J, Ichihara G
Toxicological sciences : an official journal of the Society of Toxicology 115(2) 596-606 2010年06月
DOI
Beneficial effects of growth hormone-releasing peptide on myocardial oxidative stress and left ventricular dysfunction in dilated cardiomyopathic hamsters.
Kato Y, Iwase M, Ichihara S, Kanazawa H, Hashimoto K, Noda A, Nagata K, Koike Y, Yokota M
Circulation journal : official journal of the Japanese Circulation Society 74(1) 163-170 2010年01月
DOI
Changes in neurotransmitter receptor expression levels in rat brain after 4-week exposure to 1-bromopropane.
Mohideen SS, Ichihara S, Banu S, Liu F, Kitoh J, Ichihara G
Neurotoxicology 30(6) 1078-1083 2009年11月
DOI
Comparative study on susceptibility to 1-bromopropane in three mice strains.
Liu F, Ichihara S, Mohideen SS, Sai U, Kitoh J, Ichihara G
Toxicological sciences : an official journal of the Society of Toxicology 112(1) 100-110 2009年11月
DOI
Inhibition of ischemia-induced angiogenesis by benzo[a]pyrene in a manner dependent on the aryl hydrocarbon receptor.
Ichihara S, Yamada Y, Gonzalez FJ, Nakajima T, Murohara T, Ichihara G
Biochemical and biophysical research communications 381(1) 44-49 2009年03月
DOI
Genetic factors for ischemic and hemorrhagic stroke in Japanese individuals.
Yamada Y, Metoki N, Yoshida H, Satoh K, Kato K, Hibino T, Yokoi K, Watanabe S, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y
Stroke 39(8) 2211-2218 2008年08月
DOI
Association of a polymorphism of ABCB1 with obesity in Japanese individuals.
Ichihara S, Yamada Y, Kato K, Hibino T, Yokoi K, Matsuo H, Kojima T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y
Genomics 91(6) 512-516 2008年06月
DOI
Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.
Yamada Y, Kato K, Oguri M, Yoshida T, Yokoi K, Watanabe S, Metoki N, Yoshida H, Satoh K, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y
International journal of molecular medicine 21(6) 801-808 2008年06月
Association of polymorphisms of ABCA1 and ROS1 with hypertension in Japanese individuals.
Yamada Y, Kato K, Yoshida T, Yokoi K, Matsuo H, Watanabe S, Ichihara S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y
International journal of molecular medicine 21(1) 83-89 2008年01月
Molecular genetics of myocardial infarction.
Yamada Y, Ichihara S, Nishida T
Genomic medicine 2(1-2) 7-22 2008年01月
DOI
Proinflammatory gene polymorphisms and ischemic stroke.
Yamada Y, Ichihara S, Nishida T
Current pharmaceutical design 14(33) 3590-3600 2008年
DOI
Reversibility of the adverse effects of 1-bromopropane exposure in rats.
Banu S, Ichihara S, Huang F, Ito H, Inaguma Y, Furuhashi K, Fukunaga Y, Wang Q, Kitoh J, Ando H, Kikkawa F, Ichihara G
Toxicological sciences : an official journal of the Society of Toxicology 100(2) 504-512 2007年12月
DOI
Association of a polymorphism of CYP3A4 with type 2 diabetes mellitus.
Yamada Y, Matsuo H, Watanabe S, Kato K, Yajima K, Hibino T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y
International journal of molecular medicine 20(5) 703-707 2007年11月
Prediction of genetic risk for dyslipidemia.
Yamada Y, Matsuo H, Warita S, Watanabe S, Kato K, Oguri M, Yokoi K, Metoki N, Yoshida H, Satoh K, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y
Genomics 90(5) 551-558 2007年11月
DOI
Differential cardiovascular effects of endotoxin derived from Escherichia coli or Pseudomonas aeruginosa.
Matsushita A, Iwase M, Kato Y, Ichihara S, Ichihara G, Kimata H, Hayashi K, Hashimoto K, Yokoi T, Noda A, Koike Y, Yokota M, Nagata K
Experimental animals 56(5) 339-348 2007年10月
DOI
Roles of oxidative stress and Akt signaling in doxorubicin cardiotoxicity.
Ichihara S, Yamada Y, Kawai Y, Osawa T, Furuhashi K, Duan Z, Ichihara G
Biochemical and biophysical research communications 359(1) 27-33 2007年07月
DOI
A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis.
Ichihara S, Yamada Y, Ichihara G, Nakajima T, Li P, Kondo T, Gonzalez FJ, Murohara T
Arteriosclerosis, thrombosis, and vascular biology 27(6) 1297-1304 2007年06月
DOI
Prediction of genetic risk for metabolic syndrome.
Yamada Y, Kato K, Hibino T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Ichihara S, Yoshida H, Satoh K, Nozawa Y
Atherosclerosis 191(2) 298-304 2007年04月
DOI
Gender differences in the association of gene polymorphisms with type 2 diabetes mellitus.
Yamaguchi S, Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y
International journal of molecular medicine 19(4) 631-637 2007年04月
Association of gene polymorphisms with myocardial infarction in individuals with or without conventional coronary risk factors.
Nishihama K, Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Yajima K, Hibino T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y
International journal of molecular medicine 19(1) 129-141 2007年01月
Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the RhoA-extracellular signal-regulated kinase-serum response factor signalling pathway.
Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Noda A, Izawa H, Nagata K, Yokota M
Clinical and experimental pharmacology & physiology 33(12) 1164-1171 2006年12月
DOI
Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy.
Ichihara S, Yamada Y, Ichihara G, Kanazawa H, Hashimoto K, Kato Y, Matsushita A, Oikawa S, Yokota M, Iwase M
Biochemical and biophysical research communications 350(1) 105-113 2006年11月
DOI
Genetic factors for obesity.
Yamada Y, Kato K, Kameyama T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Ichihara S, Yoshida H, Satoh K, Nozawa Y
International journal of molecular medicine 18(5) 843-851 2006年11月
Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis.
Yamaguchi S, Yamada Y, Metoki N, Yoshida H, Satoh K, Ichihara S, Kato K, Kameyama T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Nozawa Y
International journal of molecular medicine 18(5) 871-883 2006年11月
Assessment of the genetic component of hypertension.
Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Hibino T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y
American journal of hypertension 19(11) 1158-1165 2006年11月
DOI
Genetic risk for ischemic and hemorrhagic stroke.
Yamada Y, Metoki N, Yoshida H, Satoh K, Ichihara S, Kato K, Kameyama T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Nozawa Y
Arteriosclerosis, thrombosis, and vascular biology 26(8) 1920-1925 2006年08月
DOI
Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors.
Ichihara S, Obata K, Yamada Y, Nagata K, Noda A, Ichihara G, Yamada A, Kato T, Izawa H, Murohara T, Yokota M
Journal of molecular and cellular cardiology 41(2) 318-329 2006年08月
DOI
Assessment of genetic factors for type 2 diabetes mellitus.
Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Kameyama T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y
International journal of molecular medicine 18(2) 299-308 2006年08月
Assessment of genetic risk for myocardial infarction.
Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Hibino T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y
Thrombosis and haemostasis 96(2) 220-227 2006年08月
DOI
Effects of exposure of rat dams to 1-bromopropane during pregnancy and lactation on growth and sexual maturation of their offspring.
Furuhashi K, Kitoh J, Tsukamura H, Maeda K, Wang H, Li W, Ichihara S, Nakajima T, Ichihara G
Toxicology 224(3) 219-228 2006年07月
DOI
Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure.
Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Nishizawa T, Noda A, Izawa H, Nagata K, Murohara T, Yokota M
Journal of cardiovascular pharmacology 47(6) 770-779 2006年06月
DOI
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats.
Nagata K, Obata K, Xu J, Ichihara S, Noda A, Kimata H, Kato T, Izawa H, Murohara T, Yokota M
Hypertension (Dallas, Tex. : 1979) 47(4) 656-664 2006年04月
DOI
Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure.
Ichihara S, Noda A, Nagata K, Obata K, Xu J, Ichihara G, Oikawa S, Kawanishi S, Yamada Y, Yokota M
Cardiovascular research 69(3) 726-735 2006年02月
DOI
Mineralocorticoid receptor antagonism ameliorates left ventricular diastolic dysfunction and myocardial fibrosis in mildly symptomatic patients with idiopathic dilated cardiomyopathy: a pilot study.
Izawa H, Murohara T, Nagata K, Isobe S, Asano H, Amano T, Ichihara S, Kato T, Ohshima S, Murase Y, Iino S, Obata K, Noda A, Okumura K, Yokota M
Circulation 112(19) 2940-2945 2005年11月
DOI
Nicorandil promotes myocardial capillary and arteriolar growth in the failing heart of Dahl salt-sensitive hypertensive rats.
Xu J, Nagata K, Obata K, Ichihara S, Izawa H, Noda A, Nagasaka T, Iwase M, Naoe T, Murohara T, Yokota M
Hypertension (Dallas, Tex. : 1979) 46(4) 719-724 2005年10月
DOI
Serial alterations of beta-adrenergic signaling in dilated cardiomyopathic hamsters: possible role of myocardial oxidative stress.
Nishizawa T, Iwase M, Kanazawa H, Ichihara S, Ichihara G, Nagata K, Obata K, Kitaichi K, Yokoi T, Watanabe M, Tsunematsu T, Ishikawa Y, Murohara T, Yokota M
Circulation journal : official journal of the Japanese Circulation Society 68(11) 1051-1060 2004年11月
DOI
Lack of association of polymorphisms of the lymphotoxin alpha gene with myocardial infarction in Japanese.
Yamada A, Ichihara S, Murase Y, Kato T, Izawa H, Nagata K, Murohara T, Yamada Y, Yokota M
Journal of molecular medicine (Berlin, Germany) 82(7) 477-483 2004年07月
DOI
Genetic risk and gene-environment interaction in coronary artery spasm in Japanese men and women.
Murase Y, Yamada Y, Hirashiki A, Ichihara S, Kanda H, Watarai M, Takatsu F, Murohara T, Yokota M
European heart journal 25(11) 970-977 2004年06月
DOI
Genetic risk for restenosis after coronary balloon angioplasty.
Horibe H, Yamada Y, Ichihara S, Watarai M, Yanase M, Takemoto K, Shimizu S, Izawa H, Takatsu F, Yokota M
Atherosclerosis 174(1) 181-187 2004年05月
DOI
Genetic risk for coronary artery disease in individuals with or without type 2 diabetes.
Yamada Y, Ichihara S, Izawa H, Tanaka M, Yokota M
Molecular genetics and metabolism 81(4) 282-290 2004年04月
DOI
Association of gene polymorphisms with coronary artery disease in individuals with or without nonfamilial hypercholesterolemia.
Shimokata K, Yamada Y, Kondo T, Ichihara S, Izawa H, Nagata K, Murohara T, Ohno M, Yokota M
Atherosclerosis 172(1) 167-173 2004年01月
DOI
Nicorandil inhibits oxidative stress-induced apoptosis in cardiac myocytes through activation of mitochondrial ATP-sensitive potassium channels and a nitrate-like effect.
Nagata K, Obata K, Odashima M, Yamada A, Somura F, Nishizawa T, Ichihara S, Izawa H, Iwase M, Hayakawa A, Murohara T, Yokota M
Journal of molecular and cellular cardiology 35(12) 1505-1512 2003年12月
DOI
Prediction of the risk of myocardial infarction from polymorphisms in candidate genes.
Yamada Y, Izawa H, Ichihara S, Takatsu F, Ishihara H, Hirayama H, Sone T, Tanaka M, Yokota M
The New England journal of medicine 347(24) 1916-1923 2002年12月
DOI
Targeted deletion of angiotensin II type 2 receptor caused cardiac rupture after acute myocardial infarction.
Ichihara S, Senbonmatsu T, Price E Jr, Ichiki T, Gaffney FA, Inagami T
Circulation 106(17) 2244-2249 2002年10月
DOI
AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats.
Nagata K, Somura F, Obata K, Odashima M, Izawa H, Ichihara S, Nagasaka T, Iwase M, Yamada Y, Nakashima N, Yokota M
Hypertension (Dallas, Tex. : 1979) 40(2) 168-174 2002年08月
DOI

■所属部署名	環境予防医学講座
■職名	教授	■ホームページURL	http://www.jichi.ac.jp/enviro/hp/index.html

市原　佐保子ｲﾁﾊﾗ　ｻﾎｺ

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市原 佐保子 ｲﾁﾊﾗ ｻﾎｺ

プロフィール

研究キーワード

研究分野

学歴

所属学協会

学位

研究活動

論文

外部的資金

市原　佐保子ｲﾁﾊﾗ　ｻﾎｺ