研究者総覧

三浦 義正 (ミウラ ヨシマサ)

  • 内科学講座(消化器内科学部門) 講師
メールアドレス: y-miurajichi.ac.jp
Last Updated :2022/09/25

研究活動情報

論文

  • Masahiro Wada, Alan T. Lefor, Hiroyuki Mutoh, Tomonori Yano, Yoshikazu Hayashi, Keijiro Sunada, Naoyuki Nishimura, Yoshimasa Miura, Hiroyuki Sato, Hakuei Shinhata, Hironori Yamamoto, Kentaro Sugano
    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES 28 8 2428 - 2436 2014年08月 [査読有り][通常論文]
     
    Double-balloon endoscopy (DBE) has become a new standard in enteroscopy. However, it may be difficult to make a diagnosis or plan treatment strategy with endoscopic visualization alone. The addition of endoscopic ultrasonography (EUS) has the potential to improve the ability to establish the diagnosis and develop a treatment strategy. The present study was conducted to assess the feasibility and usefulness of EUS with DBE. EUS with DBE was performed in 31 of 891 patients who underwent DBE from July 2004 to March 2011 at Jichi Medical University Hospital. We analyzed the EUS findings for lesions and evaluated the usefulness of EUS considering the following three factors: qualitative diagnostic value for lesions, depth grading of lesions, and evaluation of the structure of severe strictures prior to endoscopic balloon dilation. EUS was performed for 31/32 lesions (97 %) in 31 patients. EUS findings were informative for 29/32 lesions (91 %). EUS findings were useful for establishing a qualitative diagnosis in 15/25 lesions (60 %). EUS findings for depth grading provided useful information for determining the therapeutic strategy in 11/13 lesions (85 %). EUS with DBE was useful in the evaluation of strictures for all six lesions (100 %). The overall usefulness of EUS with DBE on decision making was 72 % (23/32) in this study. EUS with DBE is feasible and useful. It provides additional information on small-bowel disease and contributes to establishing a precise diagnosis and selection of an appropriate therapeutic strategy.
  • Hideki Kumagai, Koji Yokoyama, Wakamichi Shimamura, Yoshimasa Miura, Takanori Yamagata
    PEDIATRICS INTERNATIONAL 56 4 654 - 654 2014年08月 [査読有り][通常論文]
  • Hironori Yamamoto, Yoshimasa Miura
    Gastrointestinal Endoscopy Clinics of North America 24 2 235 - 244 2014年 [査読有り][通常論文]
     
    Duodenal endoscopic submucosal dissection (ESD) is technically difficult due to the unique anatomic features. The risks include intraprocedural complications, delayed bleeding, and perforation. A small-caliber-tip transparent hood is useful. Mechanical stretching of the submucosal tissue allows safe dissection and effective prevention of bleeding with minimum muscle injury under direct visualization of the submucosal tissue and blood vessels. A short double-balloon endoscope is useful to stabilize control of the endoscope tip in distal duodenal ESD. Selection of ESD in the duodenum should be made cautiously considering both benefits and risks of the procedure. © 2014 Elsevier Inc.
  • Yoshikazu Hayashi, Hironori Yamamoto, Tomonori Yano, Aya Kitamura, Takahito Takezawa, Yuji Ino, Hirotsugu Sakamoto, Yoshimasa Miura, Hakuei Shinhata, Hiroyuki Sato, Keijiro Sunada, Kentaro Sugano
    ENDOSCOPY 45 E373 - E374 2013年12月 [査読有り][通常論文]
  • Hirotsugu Sakamoto, Hiroyuki Mutoh, Yoshimasa Miura, Miho Sashikawa, Hironori Yamamoto, Kentaro Sugano
    Gut and Liver 7 5 513 - 518 2013年09月 [査読有り][通常論文]
     
    Background/Aims: SOX9 is a marker for stem cells in the intestine, and overexpression of SOX9 is found in gastric and colon cancer however, the expression of SOX9 in nonampullary duodenal adenoma and adenocarcinoma has not yet been evaluated. This study aimed to investigate SOX9 expression in nonampullary duodenal adenoma and adenocarcinoma by immunohistochemistry. Methods: We evaluated SOX9 expression in 43 clinical samples (nonampullary duodenal adenoma in 22 lesions and nonampullary duodenal adenocarcinoma in 21 lesions) resected under endoscopic mucosal resection or endoscopic submucosal dissection. Results: SOX9 was expressed in part of the base of the normal duodenal mucosa surrounding adenomas and adenocarcinomas. In contrast, SOX9-positive cells were found in more than half of the crypts from the bottom part of the crypt in all of the 43 samples. Moreover, in 15 adenoma samples (68.2%) and 19 carcinoma samples (90.5%), SOX9 was expressed in more than three-quarters of the crypts from the bottom part of the crypt. Conclusions: SOX9 is overexpressed in nonampullary duodenal adenoma and adenocarcinoma in humans.
  • Osawa H, Yamamoto H, Miura Y, Yoshizawa M, Sunada K, Satoh K, Sugano K
    World journal of gastrointestinal endoscopy 4 356 - 361 8 2012年08月 [査読有り][通常論文]
  • Hiroyuki Osawa, Hironori Yamamoto, Yoshimasa Miura, Hironari Ajibe, Hakuei Shinhata, Mitsuyo Yoshizawa, Keijiro Sunada, Sachiko Toma, Kiichi Satoh, Kentaro Sugano
    DIGESTIVE ENDOSCOPY 24 4 231 - 236 2012年07月 [査読有り][通常論文]
     
    Background and Aim: Small-caliber endoscopy has lower resolution than normal-caliber endoscopy, limiting its use in routine outpatient practice. Flexible spectral imaging color enhancement (FICE) strengthens the color contrast of depressed-type early gastric cancer without magnification. The aim of the present study was to evaluate the detection of depressed-type early gastric cancer using small-caliber endoscopy with the FICE system. Methods: Eighty-two patients diagnosed with depressed-type early gastric cancer by standard endoscopy and biopsy were evaluated by small-caliber endoscopy. FICE images and conventional images were compared. Color differences in all 82 lesions were measured between malignant lesions and the surrounding mucosa using the Commission Internationale de L'Eclairage (CIE) 1976 color space. Results: Most cancers were readily detected as reddish lesions on FICE images. Lines of demarcation between the malignant lesion and the surrounding mucosa were easily identified with FICE images, as such cancers could be clearly distinguished from the surrounding atrophic mucosa. Greater median color differences between malignant lesions and the surrounding mucosa were present in FICE images compared with conventional images, resulting in images with better contrast (27.2 vs 18.7, P < 0.0001). Conclusions: Small-caliber endoscopy with the FICE system provides better color contrast of depressed-type early gastric cancers than conventional small-caliber endoscopy, and the FICE system may facilitate the diagnosis of this type of cancer as a new endoscopic modality.
  • Kazuhisa Yokota, Harumi Gomi, Yoshimasa Miura, Kentaro Sugano, Yuji Morisawa
    JOURNAL OF MEDICAL MICROBIOLOGY 61 3 446 - 449 2012年03月 [査読有り][通常論文]
     
    Raoultella planticola (formerly Klebsiella planticola) is a Gram-negative bacterium that has been rarely reported in association with human infection. Here we describe a case of cholangitis complicated with septic shock caused by R. planticola in an immunocompromised patient with advanced cancer who underwent endoscopic retrograde cholangiopancreatography to extract common bile duct stones. The infection was cleared by piperacillin-tazobactam treatment.
  • Naoyuki Nishimura, Hironori Yamamoto, Tomonori Yano, Yoshikazu Hayashi, Hiroyuki Sato, Yoshimasa Miura, Hakuei Shinhata, Keijiro Sunada, Kentaro Sugano
    GASTROINTESTINAL ENDOSCOPY 74 5 1157 - 1161 2011年11月 [査読有り][通常論文]
  • Taiki Aoyama, Yoshimasa Miura, Sonde Cho, Akinori Shimizu, Shinichi Mukai, Michihiro Nonaka, Toshihide Hamada, Ken Hirata, Toshio Nakanishi, Hiroki Kuniyasu
    Journal of Japanese Society of Gastroenterology 108 6 937 - 944 2011年06月 [査読有り][通常論文]
     
    We report 2 cases of early gastric cancer arising in hyperplastic polyps. The first case was 6mm in diameter, tub1, in an intestinal phenotype. The second case was 10mm in diameter, pap, in a gastric phenotype. Before resection, their biopsies had been diagnosed as atypical hyperplastic polyps. These cases suggest that small gastric hyperplastic polyps possess a certain malignant potential. If a hyperplastic polyp shows atypia in the biopsy, a complete resection should be considered.
  • Tomonori Yano, Hironori Yamamoto, Keijiro Sunada, Yoshimasa Miura, Hiroki Taguchi, Masayuki Arashiro, Mitsuyo Yoshizawa, Yoshikazu Hayashi, Tomohiko Miyata, Hozumi Tanaka, Eiji Kobayashi, Kentaro Sugano
    DIGESTIVE ENDOSCOPY 23 2 206 - 206 2011年04月 [査読有り][通常論文]
  • Yoshimasa Miura, Hironori Yamamoto, Keijiro Sunada, Tomonori Yano, Masayuki Arashiro, Tomohiko Miyata, Kentaro Sugano
    GASTROINTESTINAL ENDOSCOPY 72 3 658 - 659 2010年09月 [査読有り][通常論文]

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