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石橋 俊 イシバシ シュン

所属部署名内科学講座内分泌代謝学部門
職名教授ホームページURL

プロフィール

研究分野

  • 内科系臨床医学 / 代謝学

学位

  • 医学博士

研究活動

MISC

  • Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47.
    J Biol Chem 280: 34577-34589 2005年
  • High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.
    J Biol Chem 280: 27523-27532 2005年
  • Japan Diabetes Complications Study: Is the diagnosis of metabolic syndrome useful for predicting cardiovascular disease in asian diabetic patients? Analysis from the Japan Diabetes Complications Study.
    Diabetes Care 28: 1463-1471 2005年
  • Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma.
    Eur J Cancer 41:1316-1322 2005年
  • A single bout of exercise at higher intensity enhances glucose effectiveness in sedentary men.
    J Clin Endocinol Metab 90: 4035-4040 2005年
  • Diabetic lipemia with eruptive xanthomatosis in a lean young female with apolipoprotein E4/4.
    Diabetes Res Clin Pract 70: 183-192 2005年
  • Disruption of autosomal recessive hypercholesterolemia gene shows different phenotype in vitro and in vivo.
    Circulation Res 95: 945-52 2004年
  • Requirement for hypertension and hyperlipidemia medication in U.S. and Japanese patients with diabetes.
    Am J Med 117: 711-2 2004年
  • Scavenger receptor expressed by endothelial cells-l mediates the uptake of acetylated LDL by macrophages stimulated with lipopolysaccharide.
    J Biol Chem 279:30938-30944 2004年
  • Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats.
    Kidney Intern 66: 1493-502 2004年
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論文等(その他)閉じる
  • Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47.
    J Biol Chem 280: 34577-34589 2005年
  • High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.
    J Biol Chem 280: 27523-27532 2005年
  • Japan Diabetes Complications Study: Is the diagnosis of metabolic syndrome useful for predicting cardiovascular disease in asian diabetic patients? Analysis from the Japan Diabetes Complications Study.
    Diabetes Care 28: 1463-1471 2005年
  • Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma.
    Eur J Cancer 41:1316-1322 2005年
  • A single bout of exercise at higher intensity enhances glucose effectiveness in sedentary men.
    J Clin Endocinol Metab 90: 4035-4040 2005年
  • Diabetic lipemia with eruptive xanthomatosis in a lean young female with apolipoprotein E4/4.
    Diabetes Res Clin Pract 70: 183-192 2005年
  • Disruption of autosomal recessive hypercholesterolemia gene shows different phenotype in vitro and in vivo.
    Circulation Res 95: 945-52 2004年
  • Requirement for hypertension and hyperlipidemia medication in U.S. and Japanese patients with diabetes.
    Am J Med 117: 711-2 2004年
  • Scavenger receptor expressed by endothelial cells-l mediates the uptake of acetylated LDL by macrophages stimulated with lipopolysaccharide.
    J Biol Chem 279:30938-30944 2004年
  • Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats.
    Kidney Intern 66: 1493-502 2004年
  • Research Committeon Primary Hyperlipidemia of the Ministry of Health, Labour, and Welfare of Japan: Clinical features of familial hypercholesterolemia in Japan in a database from 1996-1998 by the research committee of the ministry of health.
    J Atherosclerosis Thrombosis 11: 146-51 2004年
  • Research Committeon Primary Hyperlipidemia of the Ministry of Health and Welfare of Japan: Mutations in Japanese subjects with primary hyperlipidemia-results from the Ministry of Health and Welfare of Japan since 1996-.
    J Atherosclerosis Thrombosis 11: 131-45 2004年
  • Hormone-sensitive lipase is required for HDL cholesteryl ester-mediated adrenal steroidogenesis.
    Mol Endocrinol 18:549-557 2004年
  • Statins augment collateral growth in response to ischemia but they do not promote cancer and atherosclerosis.
    Hpertension 43: 1214-1220 2004年
  • p53 involvement in the pathogenesis of fatty liver disease.
    J Biol Chem 279:20571-20575 2004年
  • A case of thymic enlargement in hyperthyroidism in a young woman.
    Thyroid 14:307-310 2004年
  • Decrease in serum C-reactive protein levels by troglitazone is associated with pretreatment insulin resistance, but independent of its effect on glycemia, in type 2 diabetic subjects.
    Diabetes Res Clin Prac 63: 19-26 2004年
  • Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice.
    Diabetes 53: 560-569 2004年
  • Absence of hormone-sensetive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
    J Biol Chem 279: 15084-15090 2004年
  • Comparison of pioglitazone and metformin efficacy using homeostasis model assessment.
    Diabetic Med 21: 136-141 2004年
  • Effect of moderate exercise training on peripheral glucose effectiveness, insulin sensitivity, and endogenous glucose production in healthy humans estimated by a two-compartment-labeled minimal model.
    Diabetes 53: 315-320 2004年
  • HLA-DR-DQ haplotype in rapid-onset type 1 diabetes in Japanese.
    Diabetes Care 26: 1640-1641 2003年
  • FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.
    J Biol Chem 278: 12613-12617 2003年
  • Na/H exchange isoform 1 is involved in mineralocorticoid/salt-induced cardiac injury.
    Hypertension 41: 493-498 2003年
  • Effect of glimepiride on serum adiponectin level in subjects with type 2 diabetes.
    Diabetes Care 26: 2215-2216 2003年
  • Close association of severe hyponatremia with exaggerated release of arginine vasopressin in elderly subjects with secondary adrenal insufficiency.
    Eur J Endocrinol 148: 221-226 2003年
  • p53 activation in adipocytes of obese mice.
    J Biol Chem 278: 25395-25400 2003年
  • Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism, II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.
    Mol Endocrinol 17: 1255-1267 2003年
  • Relationship between exercise training-induced increase in insulin sensitivity and adiponectinemia in healthy men.
    Endocr J 50: 233-238 2003年
  • Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR ・・・
    Mol Endocrinol 17:1240-1254 2003年
  • Early embryonic lethality caused by targeted disruption of the HMG-CoA reductase gene.
    J Biol Chem. 278:42936-41 2003年
  • Resistance to high fat diet-induced obesity associated with altered expression of adipose specific genes in hormone-sensitive lipase deficient mice.
    Am J Physiol Endocrinol Metab. 285:E1182-95 2003年
  • Neuromedin U facilitates oxytocin release from the pituitary via β adrenoceptors.
    NeuroReport 14:1997-2000 2003年
  • Roles of immunoglobulin-like loops of junctional cell adhesion molecule 4; involvement in the subcellular localization and the cell adhesion.
    Genes Cells 8:759-768 2003年
  • Transcriptional activities of nuclear SREBP-1a, -1c, and ミ2 to different target promoters of lipogenic and cholesterogenic genes.
    J Lipid Res 43: 1220-35 2002年
  • Obesity is a critical risk factor for worsening of glucose tolerance in a family with the mutant insulin receptor.
    Diabetes Care 25: 1484-1485 2002年
  • Hyperglycemia enhances VSMC proliferation with NF-kB activation by angiotensin II and E2F-1 augmentation by growth factors.
    Mol Cell Endocrinol 192: 75-84 2002年
  • Differences in E2F subunit expression in quiescent and proliferating vascular smooth muscle cells.
    Am J Physiol Heart Circ Physiol. 283:H204-12 2002年
  • An endocrinopathy characterized by dysfunction of the pituitary-adrenal axis and alopecia universalis: supporting the entity of a triple H syndrome.
    European J Endocrinol 147: 357-361. 2002年
  • Resistance to neointimal hyperplasia and fatty streak formation in mice with adrenomedullin overexpression.
    Arterioscler Thromb Vasc Biol. 22: 1310-5 2002年
  • Vasoactive intestinal peptide and cytokines enhance stem cell factor production from epidermal keratinocytes DJM-1.
    J Invest Dermatol 119: 1183-1188 2002年
  • Adrenal neutral cholesteryl ester hydrolase: identification, subcellular distribution, and sex differences.
    Endocrinology 143:801-6 2002年
  • Urinary excretion of aquaporin-2 water channel in diabetic ketoacidosis.
    Nephron 91: 167-169 2002年
  • Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha
    J Lipid Res 43:107-14 2002年
  • Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.
    J Lipid Res 43: 911-920 2002年
  • P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.
    Am J Phisiol Renal Physiol 282:F65-76 2002年
  • Pioglitazone-induced hepatic injury in a patient previously receiving troglitazone with success.
    Diabetic Med 19: 347-348 2002年
  • Decrease in urinary excretion of aquaporin-2 associated with impaired urinary concentrating ability in diabetic nephropathy.
    Nephron 92: 445-448 2002年
  • Lipolysis in the absence of hormone-sensitive lipase: Evidence for common mechanism regulating distinct lipases.
    Diabetes 51:3368-3375 2002年
  • Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.
    J Biol Chem 277: 31893-9 2002年
  • The long-term effects of self-management education for patients with type 2 diabetes on glycemic control: response to Norris et al.
    Diabetes Care 25: 2115-2116 2002年
  • Effects of lifestyle modifications on patients with type 2 diabetes: The Japan diabetes complications stydy(JDCS) study design, baseline analysis and three year-interim report.
    Horm Metab Res 34; 509-515 2002年
  • HMG-CoA reductase inhibitor decreases small dense low-density lipoprotein and remnant-like particle cholesterol in patients with type-2 diabetes.
    Life Sci. 71: 2403-2412 2002年
  • A kindred of familial acromegaly without evidence for linkage to MEN-1 locus.
    Endocrine J 49:425-431 2002年
  • Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
    J Biol Chem 277: 19353-7 2002年
  • Polyunsaturated Fatty Acids Suppress Sterol Regulatory Element-binding Protein 1c Promoter Activity by Inhibition of Liver X Receptor (LXR) Binding to LXR Response Elements.
    J Biol Chem. 277:1705-11 2002年
  • Effects of probucol on atherosclerosis of apoE-deficient or LDL receptor-deficient mice.
    Horm Metab Res 33:472-9 2001年
  • Intracellular signaling mechanisms for the P-glycoprotein-induced modulation of regulatory volume increase in the mouse proximal tubule.
    Am J Physiol Renal Physiol 282:F65-F76 2001年
  • Direct effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice.
    Br J Pharmacol. 133:1005-12 2001年
  • CD36 deficiency and insulin resistance.
    Lancet 358:243 2001年
  • Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor.
    J Biol Chem 276:37402-8 2001年
  • A Japanese patient with lipoprotein lipase deficiency homozygous for the Gly188Glu mutation prevalent worldwide.
    J Atheroscler Thromb 7:45-9 2001年
  • Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.
    Arterioscler Thromb Vasc Biol 21:372-7 2001年
  • Lipoprotein(a) and atherosclerosis.
    Arterioscler Thromb Vasc Biol. 21:1-2 2001年
  • Asialoglycoprotein Receptor Deficiency in Mice Lacking the Major Receptor Subunit. Its obligate requirement for the stable expression of oligomeric receptor.
    J Biol Chem. 276:12624-12628 2001年
  • The LDL receptor is the major pathway for beta-VLDL uptake by mouse peritoneal macrophages.
    Atherosclerosis 154:51-60 2001年
  • Thiazolidinedione- and tumor necrosis factor alpha-induced downregulation of peroxisome proliferator-activated receptor gamma mRNA in differentiated 3T3-L1 adipocytes.
    Metabolism 50:36-40 2001年
  • Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter.
    Mol Cell Biol 21:2991-3000 2001年
  • Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene.
    J Biol Chem 275:31078-85 2000年
  • Chronic inhibitory effect of insulin on plasma lipid concentrations in rats with transplanted pancreas.
    Transplantation 69:2038-42 2000年
  • Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.
    J Biol Chem. 275:31069-77 2000年
  • Hyperthyroidism presenting as dysphagia.
    Intern Med 39:472-3 2000年
  • Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia.
    J Lipid Res. 41:1199-204 2000年
  • Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity.
    Proc Natl Acad Sci U S A 97:787-92 2000年
  • Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.
    J Biol Chem 275:21324-30 2000年
  • Absence of Cd36 mutation in the original spontaneously hypertensive rats with insulin resistance.
    Nat Genet 22:226-8 1999年
  • Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes.
    J Biol Chem 274:35832-9 1999年
  • Embryonic lethality and defective neural tube closure in mice lacking squalene synthase.
    J Biol Chem 274:30843-8 1999年
  • Overexpressed lipoprotein lipase protects against atherosclerosis in apolipoprotein E knockout mice.
    J Lipid Res 40:1677-85 1999年
  • A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids.
    J Biol Chem 274:35840-4 1999年
  • Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice.
    Genes Cells 4:563-72 1999年
  • Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.
    J Clin Invest 101:1784-8 1998年
  • Lipoprotein(a) as a coronary risk factor in Japanese patients with Type II (non-insulin-dependent) diabetes mellitus. Relation with apolipoprotein(a) phenotypes.
    Diabetologia 41:1397-8 1998年
  • A truncated species of apolipoprotein B (B-38.7) in a patient with homozygous hypobetalipoproteinemia associated with diabetes mellitus.
    Arterioscler Thromb Vasc Biol 18:1330-4 1998年
  • Improved glycemic control in a diabetic patient after discontinuation of allopurinol administration.
    Diabetes Care 21:192-3 1998年
  • Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E.
    J Clin Invest 102:386-94 1998年
  • Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice.
    Lab Invest 78:423-34 1998年
  • Clinical features associated with the homozygous Trp64Arg mutation of the beta3-adrenergic receptor: no evidence for its association with obesity in Japanese.
    Arterioscler Thromb Vasc Biol 18:941-6 1998年
  • Skipping of exon 14 and possible instability of both the mRNA and the resultant truncated protein underlie a common cholesteryl ester transfer protein deficiency in Japan.
    Arterioscler Thromb Vasc Biol 17:1376-81 1997年
  • Apoptotic cell death in atherosclerotic plaques of hyperlipidemic knockout mice.
    Atherosclerosis 135:235-9 1997年
  • Bcl-2 protein inhibits oxysterol-induced apoptosis through suppressing CPP32-mediated pathway.
    FEBS Lett. 411:63-6 1997年
  • Suppression of neutral cholesterol ester hydrolase activity by antisense DNA of hormone-sensitive lipase.
    Biochem Biophys Res Commun 233:655-7 1997年
  • Effects of apo E deficiency on plasma lipid levels in mice lacking APOBEC-1.
    Biochem Biophys Res Commun. 236:375-8 1997年
  • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection.
    Nature 386:292-296 1997年
  • The major subunit of the asialoglycoprotein receptor is expressed on the hepatocellular surface in mice lacking the minor receptor subunit.
    J Biol Chem 271:21160-6 1996年
  • Transgenic mouse and gene therapy.
    Diabetes Suppl 3:S129-32 1996年
  • Transcription factor PU.1 mediates induction of c-fms in vascular smooth muscle cells: a mechanism for phenotypic change tophagocytic cells.
    Mol Cell Biol 16:2264-73 1996年
  • Enhanced expression of platelet-derived growth factor-beta receptor by high glucose. Involvement of platelet-derived growth factor in diabetic angiopathy.
    Diabetes 45:507-12 1996年
  • Synergistic effects of transforming growth factor-beta on the expression of c-fms, macrophage colony-stimulating factor receptor gene, in vascular smooth muscle cells.
    FEBS Lett 399:207-10 1996年
  • Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both.
    J Biol Chem 271:22422-7 1996年
  • Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation.
    J Biol Chem 271:18017-23 1996年
  • Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase.
    Proc Natl Acad Sci U S A 93:7242-6 1996年
  • Sick sinus syndrome in association with malignant lymphoma.
    Eur Heart J 17:968 1996年
  • Rapid genotyping of low density lipoprotein receptor knockout mice using a polymerase chain reaction technique.
    Lab Anim 29:447-9 1995年
  • Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic m・・・
    J Clin Invest 95:1133-9 1995年
  • Cloning and structural analysis of the mouse apolipoprotein B mRNA editing protein gene.
    Biochem Biophys Res Commun 214:653-62 1995年
  • Overexpression of human lipoprotein lipase protects diabetic transgenic mice from diabetic hypertriglyceridemia and hypercholesterolemia.
    Arterioscler Thromb Vasc Biol 15:1688-94 1995年
  • Overexpression of human lipoprotein lipase increases hormone-sensitive lipase activity in adipose tissue of mice.
    Biochem Biophys Res Commun 211:761-6 1995年
  • Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice.
    J Clin Invest 93:1885-93 1994年
  • Asialoglycoprotein receptor deficiency in mice lacking the minor receptor subunit.
    J Biol Chem 269:27803-6 1994年
  • The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.
    Proc Natl Acad Sci U S A. 91:4431-5 1994年
  • Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist
    Science 264:1471-4 1994年
  • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.
    J Clin Invest 92:883-93 1993年
  • Apolipoprotein E metabolism in sciatic nerves of diabetic rats. Implication for diabetic neuropathy.
    Horm Metab Res 2:82-7 1993年
  • Apolipoprotein E polymorphism is associated with plasma cholesterol response in a 7-day hospitalization study for metabolic and dietary control in NIDDM.
    Diabetes Care 16:564-9 1993年
  • Role of monocyte colony-stimulating factor in foam cell generation.
    Proc Soc Exp Biol Med 200:240-4 1992年
  • Heterogeneous mutations in the human lipoprotein lipase gene in patients with familial lipoprotein lipase deficiency.
    J Clin Invest 88:1856-64 1991年
  • Occurrence of multiple aberrantly spliced mRNAs upon a donor splice site mutation that causes familial lipoprotein lipase deficiency.
    J Biol Chem 266:24757-62 1991年
  • Overexpression of low density lipoprotein receptor on Chinese hamster ovary cells generates foam cells.
    Arterioscler Thromb. 11:1310-4 1991年
  • The enhanced cellular uptake of very-low-density lipoprotein enriched in apolipoprotein E.
    Biochim Biophys Acta 1082:63-70 1991年
  • Effects of human recombinant macrophage colony-stimulating factor on the secretion of lipoprotein lipase from macrophages.
    Arterioscler Thromb 11:1315-21 1991年
  • Oxidation-labile subfraction of human plasma low density lipoprotein isolated by ion-exchange chromatography.
    J Lipid Res 32:763-73 1991年
  • Characterization of monoclonal anti-rabbit apolipoprotein E antibodies and chemical composition of lipoproteins separated by anti-apolipoprotein E immuno-affinity chromatography.
    J Biochem (Tokyo) 109:204-10 1991年
  • Effect of tumor necrosis factor/cachectin on the activity of the low density lipoprotein receptor on human skin fibroblasts.
    Biochem Biophys Res Commun 172:1022-7 1990年
  • Monocyte colony-stimulating factor enhances uptake and degradation of acetylated low density lipoproteins and cholesterol esterification in human monocyte-derived macrophages.
    J Biol Chem 265:14109-17 1990年
  • Apolipoprotein E and lipoprotein lipase secreted from human monocyte-derived macrophages modulate very low density lipoprotein uptake.
    J Biol Chem 265:3040-7 1990年
  • Effect of exogenous apo E on the cellular binding of lipoproteins.
    Gerontology 36 Suppl 1:42-8 1990年
  • Cholesterol-free diet with a high ratio of polyunsaturated to saturated fatty acids in heterozygous familial hypercholesterolemia: significant lowering effect on plasma cholesterol.
    Horm Metab Res. 22:246-51 1990年
  • Human monocyte colony-stimulating factor enhances the clearance of lipoproteins containing apolipoprotein B-100 via both low density lipoprotein receptor-dependent and -independent pathways in rabbits.
    J Biol Chem 265:12869-75 1990年
  • Plasma cholesterol-lowering activity of monocyte colony-stimulating factor (M-CSF).
    Ann N Y Acad Sci 587:362-70 1990年
  • Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
    Science 250:1273-5 1990年
  • The release of hepatic triglyceride lipase from rat monolayered hepatocytes in primary culture.
    Endocrinol Jpn 37:437-42 1990年
  • Enhanced lipoprotein lipase secretion from human monocyte-derived macrophages caused by hypertriglyceridemic very low density lipoproteins.
    Arteriosclerosis 9:650-5 1989年
  • Composition of very-low-density lipoproteins in non-insulin-dependent diabetes mellitus.
    Clin Chem 35:808-12 1989年
  • A neonatal case of apolipoprotein C-II deficiency.
    Eur J Pediatr 148:550-2 1989年
  • Plasma apolipoproteins in patients with multi-infarct dementia.
    Atherosclerosis 79:257-60 1989年
  • Increased clearance of plasma cholesterol after injection of apolipoprotein E into Watanabe heritable hyperlipidemic rabbits.
    Proc Natl Acad Sci U S A 86:665-9 1989年
  • Enhanced synthesis and secretion of apolipoprotein E from sciatic nerves of streptozotocin-induced diabetic rats after injury.
    Biochem Biophys Res Commun 155:283-8 1988年
  • High-cholesterol diet-induced lipoproteins stimulate lipoprotein lipase secretion in cultured rat alveolar macrophages.
    Biochim Biophys Acta 922:103-10 1987年
  • Down-regulation of hepatic LDL receptor protein and messenger RNA in fasted rabbits.
    J Biochem (Tokyo) 104:712-6 1988年
  • Sick sinus syndrome in malignant lymphoma involving the heart.
    Nippon Naika Gakkai Zasshi 76:100-5 1987年
  • Human recombinant TNF suppresses lipoprotein lipase activity and stimulates lipolysis in 3T3-L1 cells.
    J Biochem (Tokyo) 101:331-8 1987年
  • Lipoprotein lipase in mouse peritoneal macrophages: the effects of insulin and dexamethasone.
    J Biochem (Tokyo) 100:1373-8 1986年
  • Human recombinant TNF suppresses lipoprotein lipase activity and stimulates lipolysis in 3T3-L1 cells.
    J Biochem (Tokyo) 101:331-8 1987年
  • Plasma apolipoprotein CII levels in hypertriglyceridemia
    Metabolism 35:781-5 1986年
  • Immunohistochemical localization of apolipoprotein E in atherosclerotic lesions of the aorta and coronary arteries.
    Atherosclerosis 60:1-6 1986年
  • Hyperlipidaemia in patients with hypopituitarism.
    Acta Endocrinol (Copenh) 110:456-60 1985年
  • A platelet factor stimulating the proliferation of vascular endothelial cells. Partial purification and characterization.
    Exp Cell Res 159:487-94 1985年
  • A case of polymyositis associated with hypertriglyceridemia due to decline of lipoprotein lipase activity.
    Nippon Naika Gakkai Zasshi 73:368-73 1984年


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