Y. Matsumura, J. Matsumoto, K. Idoguchi, H. Kondo, T. Ishida, Y. Kon, K. Tomita, K. Ishida, T. Hirose, K. Umakoshi, T. Funabiki, Direct-Iabo Investigators, Naohiro Hagawa, Tokiya Ishida, Kenichiro Ishida, Eiji Yamamura, Kensuke Umakoshi, Kosuke Chiris Yamada, Yosuke Homma, Tomoya Hirose, Mahiro Fujii, Chikao Ito, Takahiro Yamamoto, Tomohiko Orita, Junichi Matsumoto, Koji Idoguchi, Yuri Kon, Keisuke Tomita, Takafumi Shinjo, Yukitoshi Toyoda European Journal of Trauma and Emergency Surgery 44 1 -7 2017年08月
[査読無し][通常論文] Purpose: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is now a feasible and less invasive resuscitation procedure. This study aimed to compare the clinical course of trauma and non-trauma patients undergoing REBOA. Methods: Patient demographics, etiology, bleeding sites, hemodynamic response, length of critical care, and cause of death were recorded. Characteristics and outcomes were compared between non-trauma and trauma patients. Kaplan–Meier survival analysis was then conducted. Results: Between August 2011 and December 2015, 142 (36 non-trauma
106 trauma) cases were analyzed. Non-traumatic etiologies included gastrointestinal bleeding, obstetrics and gynecology-derived events, visceral aneurysm, abdominal aortic aneurysm, and post-abdominal surgery. The abdomen was a common bleeding site (69%), followed by the pelvis or extra-pelvic retroperitoneum. None of the non-trauma patients had multiple bleeding sites, whereas 45% of trauma patients did (P <
0.001). No non-trauma patients required resuscitative thoracotomy compared with 28% of the trauma patients (P <
0.001). Non-trauma patients presented a lower 24-h mortality than trauma patients (19 vs. 51%, P = 0.001). The non-trauma cases demonstrated a gradual but prolonged increased mortality, whereas survival in trauma cases rapidly declined (P = 0.009) with similar hospital mortality (68 vs. 64%). Non-trauma patients who survived for 24 h had 0 ventilator-free days and 0 ICU-free days vs. a median of 19 and 12, respectively, for trauma patients (P = 0.33 and 0.39, respectively). Non-hemorrhagic death was more common in non-trauma vs. trauma patients (83 vs. 33%, P <
0.001). Conclusions: Non-traumatic hemorrhagic shock often resulted from a single bleeding site, and resulted in better 24-h survival than traumatic hemorrhage among Japanese patients who underwent REBOA. However, hospital mortality increased steadily in non-trauma patients affected by non-hemorrhagic causes after a longer period of critical care.