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藤原 研 フジワラ ケン

所属部署名解剖学講座組織学部門
職名准教授ホームページURL

プロフィール

研究キーワード

    内分泌, 神経内分泌, 細胞間相互作用, 下垂体

研究分野

  • 基礎医学 / 解剖学一般(含組織学・発生学)
  • 内科系臨床医学 / 内分泌学

経歴

  • 2005年04月
    -
    現在
    自治医科大学医学部解剖学講座組織学部門
  • 2003年04月
    -
    2005年03月
    自治医科大学医学部生理学講座統合生理学部門(ポストドクター)
  • 2000年04月
    -
    2003年03月
    日本学術振興会特別研究員(DC1)

学歴

  • 2000年04月
    -
    2003年03月
    埼玉大学 理工学研究科博士後期課程 生物環境科学専攻

所属学協会

  • 米国内分泌学会
  • 日本内分泌学会
  • 日本神経内分泌学会
  • 日本解剖学会
  • 日本比較内分泌学会
  • 日本組織細胞化学会
  • 日本内分泌病理学会
  • 日本下垂体研究会
所属学協会を全て表示する
所属学協会閉じる
  • 米国内分泌学会
  • 日本内分泌学会
  • 日本神経内分泌学会
  • 日本解剖学会
  • 日本比較内分泌学会
  • 日本組織細胞化学会
  • 日本内分泌病理学会
  • 日本下垂体研究会

委員歴

  • 2013年
    -
    現在
    日本下垂体研究会 評議委員
  • 2009年
    -
    現在
    日本比較内分泌学会 編集委員
審議会等委員を全て表示する
審議会等委員閉じる
  • 2013年
    -
    現在
    日本下垂体研究会 評議委員
  • 2009年
    -
    現在
    日本比較内分泌学会 編集委員

学位

  • 理学博士

研究活動

論文

  • In situ hybridization analysis of the temporospatial expression of the midkine/pleiotrophin family in rat embryonic pituitary gland.
    Fujiwara K, Maliza R, Tofrizal A, Batchuluun K, Ramadhani D, Tsukada T, Azuma M, Horiguchi K, Kikuchi M, Yashiro T
    Cell and tissue research 2014年05月
  • Expression of chemokine CXCL10 in dendritic-cell-like S100β-positive cells in rat anterior pituitary gland.
    Horiguchi K, Fujiwara K, Higuchi M, Yoshida S, Tsukada T, Ueharu H, Chen M, Hasegawa R, Takigami S, Ohsako S, Yashiro T, Kato T, Kato Y
    Cell and tissue research 2014年04月
  • Isolation of dendritic-cell-like S100β-positive cells in rat anterior pituitary gland.
    Horiguchi K, Fujiwara K, Yoshida S, Higuchi M, Tsukada T, Kanno N, Yashiro T, Tateno K, Osako S, Kato T, Kato Y
    Cell and tissue research 2014年04月
  • Changes in fine structure of pericytes and novel desmin-immunopositive perivascular cells during postnatal development in rat anterior pituitary gland.
    Jindatip D, Fujiwara K, Horiguchi K, Tsukada T, Kouki T, Yashiro T
    Anatomical science international 88 196-203 2013年09月
  • Expression of the cell-surface heparan sulfate proteoglycan syndecan-2 in developing rat anterior pituitary gland.
    Horiguchi K, Syaidah R, Fujiwara K, Tsukada T, Ramadhani D, Jindatip D, Kikuchi M, Yashiro T
    Cell and tissue research 353 473-481 2013年09月
  • Laminin and collagen modulate expression of the small leucine-rich proteoglycan fibromodulin in rat anterior pituitary gland.
    Syaidah R, Horiguchi K, Fujiwara K, Tsukada T, Kikuchi M, Yashiro T
    Cell and tissue research 2013年08月
  • Reassembly of anterior pituitary organization by hanging drop three-dimensional cell culture.
    Tsukada T, Kouki T, Fujiwara K, Ramadhani D, Horiguchi K, Kikuchi M, Yashiro T
    Acta histochemica et cytochemica 46 121-127 2013年08月
  • Localization of Notch signaling molecules and their effect on cellular proliferation in adult rat pituitary.
    Tando Y, Fujiwara K, Yashiro T, Kikuchi M
    Cell and tissue research 351 511-519 2013年03月
  • In Situ Hybridization Method Reveals (Pro)renin Receptor Expressing Cells in the Pituitary Gland of Rats: Correlation with Anterior Pituitary Hormones.
    Takahashi K, Yatabe M, Fujiwara K, Hirose T, Totsune K, Yashiro T
    Acta histochemica et cytochemica 46 47-50 2013年02月
  • Expression of small leucine-rich proteoglycans in rat anterior pituitary gland.
    Horiguchi K, Syaidah R, Fujiwara K, Tsukada T, Ramadhani D, Jindatip D, Kikuchi M, Yashiro T
    Cell and tissue research 351 207-212 2013年01月
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論文等(論文)閉じる
  • In situ hybridization analysis of the temporospatial expression of the midkine/pleiotrophin family in rat embryonic pituitary gland.
    Fujiwara K, Maliza R, Tofrizal A, Batchuluun K, Ramadhani D, Tsukada T, Azuma M, Horiguchi K, Kikuchi M, Yashiro T
    Cell and tissue research 2014年05月
  • Expression of chemokine CXCL10 in dendritic-cell-like S100β-positive cells in rat anterior pituitary gland.
    Horiguchi K, Fujiwara K, Higuchi M, Yoshida S, Tsukada T, Ueharu H, Chen M, Hasegawa R, Takigami S, Ohsako S, Yashiro T, Kato T, Kato Y
    Cell and tissue research 2014年04月
  • Isolation of dendritic-cell-like S100β-positive cells in rat anterior pituitary gland.
    Horiguchi K, Fujiwara K, Yoshida S, Higuchi M, Tsukada T, Kanno N, Yashiro T, Tateno K, Osako S, Kato T, Kato Y
    Cell and tissue research 2014年04月
  • Changes in fine structure of pericytes and novel desmin-immunopositive perivascular cells during postnatal development in rat anterior pituitary gland.
    Jindatip D, Fujiwara K, Horiguchi K, Tsukada T, Kouki T, Yashiro T
    Anatomical science international 88 196-203 2013年09月
  • Expression of the cell-surface heparan sulfate proteoglycan syndecan-2 in developing rat anterior pituitary gland.
    Horiguchi K, Syaidah R, Fujiwara K, Tsukada T, Ramadhani D, Jindatip D, Kikuchi M, Yashiro T
    Cell and tissue research 353 473-481 2013年09月
  • Laminin and collagen modulate expression of the small leucine-rich proteoglycan fibromodulin in rat anterior pituitary gland.
    Syaidah R, Horiguchi K, Fujiwara K, Tsukada T, Kikuchi M, Yashiro T
    Cell and tissue research 2013年08月
  • Reassembly of anterior pituitary organization by hanging drop three-dimensional cell culture.
    Tsukada T, Kouki T, Fujiwara K, Ramadhani D, Horiguchi K, Kikuchi M, Yashiro T
    Acta histochemica et cytochemica 46 121-127 2013年08月
  • Localization of Notch signaling molecules and their effect on cellular proliferation in adult rat pituitary.
    Tando Y, Fujiwara K, Yashiro T, Kikuchi M
    Cell and tissue research 351 511-519 2013年03月
  • In Situ Hybridization Method Reveals (Pro)renin Receptor Expressing Cells in the Pituitary Gland of Rats: Correlation with Anterior Pituitary Hormones.
    Takahashi K, Yatabe M, Fujiwara K, Hirose T, Totsune K, Yashiro T
    Acta histochemica et cytochemica 46 47-50 2013年02月
  • Expression of small leucine-rich proteoglycans in rat anterior pituitary gland.
    Horiguchi K, Syaidah R, Fujiwara K, Tsukada T, Ramadhani D, Jindatip D, Kikuchi M, Yashiro T
    Cell and tissue research 351 207-212 2013年01月
  • Brain-derived neurotrophic factor in VMH as the causal factor for and therapeutic tool to treat visceral adiposity and hyperleptinemia in type 2 diabetic Goto-Kakizaki rats.
    Maekawa F, Fujiwara K, Toriya M, Maejima Y, Nishio T, Toyoda Y, Nohara K, Yashiro T, Yada T
    Frontiers in synaptic neuroscience 5 7 2013年
  • Laminin isoforms and laminin-producing cells in rat anterior pituitary.
    Ramadhani D, Tsukada T, Fujiwara K, Horiguchi K, Kikuchi M, Yashiro T
    Acta histochemica et cytochemica 45 309-315 2012年10月
  • Transmission and scanning electron microscopy study of the characteristics and morphology of pericytes and novel desmin-immunopositive perivascular cells before and after castration in rat anterior pituitary gland.
    Jindatip D, Fujiwara K, Kouki T, Yashiro T
    Anatomical science international 87 165-173 2012年09月
  • Expression of the proteoglycan syndecan-4 and the mechanism by which it mediates stress fiber formation in folliculostellate cells in the rat anterior pituitary gland.
    Horiguchi K, Kouki T, Fujiwara K, Tsukada T, Ly F, Kikuchi M, Yashiro T
    The Journal of endocrinology 214 199-206 2012年08月
  • Expression of chemokine CXCL12 and its receptor CXCR4 in folliculostellate (FS) cells of the rat anterior pituitary gland: the CXCL12/CXCR4 axis induces interconnection of FS cells.
    Horiguchi K, Ilmiawati C, Fujiwara K, Tsukada T, Kikuchi M, Yashiro T
    Endocrinology 153 1717-1724 2012年04月
  • Matrix metalloproteinase-9 expression in folliculostellate cells of rat anterior pituitary gland.
    Ilmiawati C, Horiguchi K, Fujiwara K, Yashiro T
    The Journal of endocrinology 212 363-370 2012年03月
  • Live staining and isolation of specific hormone-producing cells from rat anterior pituitary by cytochemistry with lectins and cholera toxin B subunit.
    Kikuchi M, Kusumoto K, Fujiwara K, Takahashi K, Tando Y, Yashiro T
    Acta histochemica et cytochemica 44 159-164 2011年08月
  • Caveolin 3-mediated integrin β1 signaling is required for the proliferation of folliculostellate cells in rat anterior pituitary gland under the influence of extracellular matrix.
    Horiguchi K, Fujiwara K, Ilmiawati C, Kikuchi M, Tsukada T, Kouki T, Yashiro T
    The Journal of endocrinology 210 29-36 2011年07月
  • The extracellular matrix component laminin promotes gap junction formation in the rat anterior pituitary gland.
    Horiguchi K, Kouki T, Fujiwara K, Kikuchi M, Yashiro T
    The Journal of endocrinology 208 225-232 2011年03月
  • In situ hybridization reveals that type I and III collagens are produced by pericytes in the anterior pituitary gland of rats.
    Fujiwara K, Jindatip D, Kikuchi M, Yashiro T
    Cell and tissue research 342 491-495 2010年12月
  • Long-term infusion of brain-derived neurotrophic factor reduces food intake and body weight via a corticotrophin-releasing hormone pathway in the paraventricular nucleus of the hypothalamus.
    Toriya M, Maekawa F, Maejima Y, Onaka T, Fujiwara K, Nakagawa T, Nakata M, Yada T.
    J Neuroendocrinol. 22 987-995 2010年09月
  • Effect of E-cadherin expression on hormone production in rat anterior pituitary lactotrophs in vitro.
    Kusumoto K, Kikuchi M, Fujiwara K, Horiguchi K, Kouki T, Kawanishi K, Yashiro T.
    Acta Histochem Cytochem. 43 83-89 2010年05月
  • Living-cell imaging of transgenic rat anterior pituitary cells in primary culture reveals novel characteristics of folliculo-stellate cells.
    Horiguchi K, Kikuchi M, Kusumoto K, Fujiwara K, Kouki T, Kawanishi K, Yashiro T.
    J Endocrinol. 204 115-123 2010年02月
  • Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway
    Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T
    Cell Metab. 10 355-365 2009年11月
  • Spatio-temporal relation between cadherin switching and cytogenesis of hormone-producing cells in the developing rat adenohypophysis.
    Kikuchi M, Yatabe M, Fujiwara K, Horiguchi K, Kusumoto K, Kouki T, Sakamoto A, Yashiro T
    Anatomical science international 84 155-160 2009年09月
  • Estrogen receptor alpha regulates retinaldehyde dehydrogenase 1 expression in rat anterior pituitary cells
    Fujiwara K, Kikuchi M, Horiguchi K, Kusumoto K, Kouki T, Kawanishi K, Yashiro T
    Endocr J. 56 963-973 2009年08月
  • Blockade of PrRP attenuates MPTP-induced toxicity in mice.
    Sun B, Mochiduki A, Nakamura K, Yokoyama K, Adachi S, Fujiwara K, Matsumoto H, Inoue K
    Peptides 30 1267-1275 2009年07月
  • Immunohistochemistry of connexin 43 throughout anterior pituitary gland in a transgenic rat with green fluorescent protein-expressing folliculo-stellate cells.
    Horiguchi K, Fujiwara K, Kouki T, Kikuchi M, Yashiro T
    Anatomical science international 83 256-260 2008年12月
  • Reduction of retinaldehyde dehydrogenase 1 expression and production in estrogen-induced prolactinoma of rat.
    Fujiwara K, Davaadash B, Yatabe M, Kikuchi M, Horiguchi K, Kusumoto K, Kouki T, Yashiro T
    Medical molecular morphology 41 126-131 2008年09月
  • Estrogen suppresses retinaldehyde dehydrogenase 1 expression in the anterior pituitary glands of female rats.
    Fujiwara K, Davaadash B, Kikuchi M, Takigami S, Yashiro T
    Endocrine journal 55 91-96 2008年03月
  • In vivo correlation between c-Fos expression and corticotroph stimulation by adrenocorticotrophic hormone secretagogues in rat anterior pituitary gland.
    Takigami S, Fujiwara K, Kikuchi M, Yashiro T
    Cell and tissue research 331 589-594 2008年03月
  • Appearance of prolactin-releasing peptide-producing cells in the area postrema of postnatal rats.
    Fujiwara K, Usui K, Yashiro T, Inoue K
    Regulatory peptides 145 33-36 2008年01月
  • Activation of cholecystokinin neurons in the dorsal pallium of the telencephalon is indispensable for the acquisition of chick imprinting behavior.
    Maekawa F, Nakamori T, Uchimura M, Fujiwara K, Yada T, Tsukahara S, Kanamatsu T, Tanaka K, Ohki-Hamazaki H
    Journal of neurochemistry 102 1645-1657 2007年09月
  • Expression of retinaldehyde dehydrogenase 1 in the anterior pituitary glands of adult rats.
    Fujiwara K, Kikuchi M, Takigami S, Kouki T, Yashiro T
    Cell and tissue research 329 321-327 2007年08月
  • Changes in E- and N-cadherin expression in developing rat adenohypophysis.
    Kikuchi M, Yatabe M, Kouki T, Fujiwara K, Takigami S, Sakamoto A, Yashiro T
    Anatomical record (Hoboken) 290 486-490 2007年05月
  • Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway.
    Kohno D, Nakata M, Maekawa F, Fujiwara K, Maejima Y, Kuramochi M, Shimazaki T, Okano H, Onaka T, Yada T
    Endocrinology 148 2251-2263 2007年05月
  • Oleic acid glucose-independently stimulates glucagon secretion by increasing cytoplasmic Ca2+ via endoplasmic reticulum Ca2+ release and Ca2+ influx in the rat islet alpha-cells.
    Fujiwara K, Maekawa F, Dezaki K, Nakata M, Yashiro T, Yada T
    Endocrinology 148 2496-2504 2007年05月
  • Expression of retinaldehyde dehydrogenase (RALDH)2 and RALDH3 but not RALDH1 in the developing anterior pituitary glands of rats.
    Fujiwara K, Maekawa F, Kikuchi M, Takigami S, Yada T, Yashiro T
    Cell and tissue research 328 129-135 2007年04月
  • Distinctive localization of N- and E-cadherins in rat anterior pituitary gland.
    Kikuchi M, Yatabe M, Fujiwara K, Takigami S, Sakamoto A, Soji T, Yashiro T
    The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 288 1183-1189 2006年11月
  • Hyperphagia in Diabetic Goto-Kakizaki Rats is Associated with Leptin Resistance and Elevation of Neuropeptide Y mRNA in the Arcuate Nucleus
    Maekawa F, Fujiwara K, Kohno D, Kuramochi M, Kurita H, Yada T
    J Neuroendocrinol. 18 748-756 2006年10月
  • Pituitary adenylate cyclase-activating polypeptide neurons of the ventromedial hypothalamus project to the midbrain central gray.
    Maekawa F, Fujiwara K, Tsukahara S, Yada T
    Neuroreport 17 221-224 2006年02月
  • Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release.
    Fujiwara K, Maekawa F, Yada T
    American journal of physiology. Endocrinology and metabolism 289 E670-7 2005年10月
  • Estrogen suppresses the stress response of prolactin-releasing peptide-producing cells.
    Adachi S, Mochiduki A, Nemoto H, Sun B, Fujiwara K, Matsumoto H, Inoue K
    Neuroscience letters 380 311-315 2005年06月
  • Identification of the prolactin-releasing peptide-producing cell in the rat adrenal gland.
    Fujiwara K, Matsumoto H, Yada T, Inoue K
    Regulatory peptides 126 97-102 2005年03月
  • Nicotine stimulates prolactin-releasing peptide (PrRP) cells and non-PrRP cells in the solitary nucleus.
    Sun B, Nemoto H, Fujiwara K, Adachi S, Inoue K
    Regulatory peptides 126 91-96 2005年03月
  • Physiological roles of prolactin-releasing peptide.
    Sun B, Fujiwara K, Adachi S, Inoue K
    Regulatory peptides 126 27-33 2005年03月
  • Appearance of prolactin-releasing peptide-producing neurons in the area postrema of adrenalectomized rats.
    Fujiwara K, Maruyama M, Usui K, Sakai T, Matsumoto H, Hinuma S, Kitada C, Inoue K
    Neuroscience letters 338 127-130 2003年02月
  • Immunocytochemical localization of a galanin-like peptide (GALP) in pituicytes of the rat posterior pituitary gland.
    Fujiwara K, Adachi S, Usui K, Maruyama M, Matsumoto H, Ohtaki T, Kitada C, Onda H, Fujino M, Inoue K
    Neuroscience letters 317 65-68 2002年01月
  • Prolactin-releasing peptide as a novel stress mediator in the central nervous system.
    Maruyama M, Matsumoto H, Fujiwara K, Noguchi J, Kitada C, Fujino M, Inoue K.
    Endocrinology 142(5) 2032-2038 2001年05月
  • Stimulation of corticotropin-releasing hormone-mediated adrenocorticotropin secretion by central administration of prolactin-releasing peptide in rats.
    Matsumoto H, Maruyama M, Noguchi J, Horikoshi Y, Fujiwara K, Kitada C, Hinuma S, Onda H, Nishimura O, Inoue K, Fujino M.
    Neuroscience Letters 285 234-238 2000年
  • Central administration of prolactin-releasing peptide stimulates oxytocin release in rats. Neurosci Lett.
    Maruyama M, Matsumoto H, Fujiwara K, Noguchi J, Kitada C, Hinuma S, Onda H, Nishimura O, Fujino M, Higuchi T, Inoue K.
    Neuroscience Letters 276 193-196 1999年12月
  • Immunocytochemical localization of prolactin-releasing peptide in the rat brain.
    Maruyama M, Matsumoto H, Fujiwara K, Kitada C, Hinuma S, Onda H, Fujino M, Inoue K.
    Endocrinology 140 2326-2333 1999年05月

MISC

  • Immunocytochemical localization of Prolactin-Releasing Peptide in the Rat Brain
    Maruyama M, Matsumoto H, Fujiwara K, Kitada C, Hinuma S, Onda H, Fujino M, Inoue K
    Endocrinology 140 2326-2333 1999年
  • Central administration of prolactin-releasing peptide stimulates oxytocin release in rats
    Maruyama M, Matsumoto H, Fujiwara K, Noguchi J, Kitada C, Hinuma S, Onda H, Nishimura O, Fujino M, Higuchi H, Inoue K
    Neuroscience letters 276(3) 193-196 1999年
  • Stimulation of corticotropin-releasing hormone-mediated adrenocorticotropin secretion by central administration of prolactin -releasing peptide in rats
    Matsumoto H, Maruyama M, Noguchi J, Horikoshi Y, Fujiwara K, Kitada C, Hinuma S, Onda H, Nishimura O, Inoue K, Fujino M
    Neuroscience Letters 285 234-238 2000年
  • Prolactin-releasing peptide as a novel stress mediator in the central nervous system
    Maruyama M, Matsumoto H, Fujiwara K, Noguchi J, Kitada C, Fujino M, Inoue K
    Endocrinology 142 2032-2038 2001年
  • Immunocytochemical localization of a galanin-like peptide (GALP) in pituicytes of the rat posterior pituitary gland
    Fujiwara K, Adachi S, Usui K, Maruyama M, Matsumoto H, Ohtaki T, Kitada C, Onda H, Fujino M, Inoue K
    Neuroscience Letters 317 65-68 2002年
  • Appearance of prolactin-releasing peptide-producing neurons in the area postrema of adrenalectomized rats
    Fujiwara K, Maruyama M, Usui K, Sakai T, Matsumoto H, Hinuma S, Kitada C, Inoue K
    Neuroscience Letters 338 127-130 2003年
  • Nicotine stimulates prolactin-releasing peptide (PrRP) cells and non-PrRP cells in the solitary nucleus
    Sun B, Nemoto H, Fujiwara K, Adachi S, Inoue K
    Regulatory Peptides 126 91-96 2005年
  • Identification of the Prolactin-Releasing Peptide-Producing Cell in the Rat Adrenal Gland
    Fujiwara K, Matsumoto H, Yada T, Inoue K
    Regulatory Peptides 126 97-102 2005年
  • Physiological role of prolactin-releasing peptide
    Sun B, Fujiwara K, Adachi S, Inoue K
    Regulatory Peptides 126 27-33 2005年
  • NPYと自律神経
    藤原 研、矢田俊彦
    臨床神経科学 21 1408-1410 2003年
論文等(その他)を全て表示する
論文等(その他)閉じる
  • Immunocytochemical localization of Prolactin-Releasing Peptide in the Rat Brain
    Maruyama M, Matsumoto H, Fujiwara K, Kitada C, Hinuma S, Onda H, Fujino M, Inoue K
    Endocrinology 140 2326-2333 1999年
  • Central administration of prolactin-releasing peptide stimulates oxytocin release in rats
    Maruyama M, Matsumoto H, Fujiwara K, Noguchi J, Kitada C, Hinuma S, Onda H, Nishimura O, Fujino M, Higuchi H, Inoue K
    Neuroscience letters 276(3) 193-196 1999年
  • Stimulation of corticotropin-releasing hormone-mediated adrenocorticotropin secretion by central administration of prolactin -releasing peptide in rats
    Matsumoto H, Maruyama M, Noguchi J, Horikoshi Y, Fujiwara K, Kitada C, Hinuma S, Onda H, Nishimura O, Inoue K, Fujino M
    Neuroscience Letters 285 234-238 2000年
  • Prolactin-releasing peptide as a novel stress mediator in the central nervous system
    Maruyama M, Matsumoto H, Fujiwara K, Noguchi J, Kitada C, Fujino M, Inoue K
    Endocrinology 142 2032-2038 2001年
  • Immunocytochemical localization of a galanin-like peptide (GALP) in pituicytes of the rat posterior pituitary gland
    Fujiwara K, Adachi S, Usui K, Maruyama M, Matsumoto H, Ohtaki T, Kitada C, Onda H, Fujino M, Inoue K
    Neuroscience Letters 317 65-68 2002年
  • Appearance of prolactin-releasing peptide-producing neurons in the area postrema of adrenalectomized rats
    Fujiwara K, Maruyama M, Usui K, Sakai T, Matsumoto H, Hinuma S, Kitada C, Inoue K
    Neuroscience Letters 338 127-130 2003年
  • Nicotine stimulates prolactin-releasing peptide (PrRP) cells and non-PrRP cells in the solitary nucleus
    Sun B, Nemoto H, Fujiwara K, Adachi S, Inoue K
    Regulatory Peptides 126 91-96 2005年
  • Identification of the Prolactin-Releasing Peptide-Producing Cell in the Rat Adrenal Gland
    Fujiwara K, Matsumoto H, Yada T, Inoue K
    Regulatory Peptides 126 97-102 2005年
  • Physiological role of prolactin-releasing peptide
    Sun B, Fujiwara K, Adachi S, Inoue K
    Regulatory Peptides 126 27-33 2005年
  • NPYと自律神経
    藤原 研、矢田俊彦
    臨床神経科学 21 1408-1410 2003年
  • 視床下部・全身代謝・ストレスによる摂食調節
    河野大輔、藤原 研、前川文彦、倉持素樹、尾仲達史、矢田俊彦
    肥満研究 9 235-243 2003年
  • 新しいインスリン分泌機構:開口放出制御分子と脂肪酸受容体
    八重倉和朗、藤原 研、矢田俊彦
    内分泌・糖尿病科 17 543-549 2003年
  • Estrogen suppresses the stress response of prolactin-releasing peptide-producing cells
    Adachi S, Mochiduki A, Nemoto H, Sun B, Fujiwara K, Matsumoto H, Inoue K
    Neuroscience Letters 380 311-315 2005年
  • Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet b-cells: mediation by phospholipase C- and L-type Ca2+ channel and link to insulin release
    Fujiwara K, Maekawa F, Yada T
    American Journal of Physiology. Endocrinology and Metabolism 289 E670-E677 2005年
  • PACAP neurons of the ventromedial hypothalamus project to midbrain central gray
    Maekawa F, Fujiwara K, Tsukahara S, Yada T
    Neuroreport 17 221-224 2006年
  • Young adult-specific hyperphagia in diabetic Goto-Kakizaki rats is associated with leptin resistance and elevation of neuropeptide Y mRNA in the arcuate nucleus
    Maekawa F, Fujiwara K, Kohno D, Kuramochi M, Kurita H, Yada T
    Journal of Neuroendocrinology 18 748-756 2006年
  • Distinctive localization of N- and E-cadherins in rat anterior pituitary gland
    Kikuchi M, Yatabe M, Fujiwara K, Takigami S, Sakamoto A, Soji T, Yashiro T
    Anat Rec A Discov Mol Cell Evol Biol. 288A 1183-1189 2006年
  • Expression of retinaldehyde dehydrogenase (RALDH)2 and RALDH3 but not RALDH1 in the developing anterior pituitary glands of rats
    Fujiwara K, Maekawa F, Kikuchi M, Takigami S, Yada T, Yashiro T
    Cell and Tissue Research 328 129-135 2007年
  • Changes in E- and N-cadherin expression in developing rat adenohypophysis
    Kikuchi M, Yatabe M, Kouki T, Fujiwara K, Takigami S, Sakamoto A, Yashiro T
    Anat Rec (Hoboken) 290 486-490 2007年
  • Oleic acid glucose-independently stimulates glucagon secretion by increasing cytoplasmic Ca2+ via ER Ca2+ release and Ca2+ influx in the rat islet a-cells
    Fujiwara K, Maekawa F, Dezaki K, Nakata M, Yashiro T, Yada T
    Endocrinology 148 2496-2504 2007年
  • Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway
    Kohno D, Nakata M, Maekawa F, Fujiwara K, Maejima Y, Kuramochi M, Shimazaki T, Okano H, Onaka T, Yada T
    Endocrinology 148 2251-2263 2007年
  • Expression of retinaldehyde dehydrogenase 1 in the anterior pituitary glands of adult rats
    Fujiwara K, Kikuchi M, Takigami S, Kouki T, Yashiro T
    Cell and Tissue Research 329 321-327 2007年
  • Activation of cholecystokinin neurons in the dorsal pallium of the telencephalon is indispensable for the acquisition of chick imprinting behavior
    Maekawa F, Nakamori T, Uchimura M, Fujiwara K, Yada T, Tsukahara S, Kanamatsu T, Tanaka K, Ohki-Hamazaki H
    Journal of Neurochemistry 102(5) 1645-1657 2007年
  • Appearance of prolactin-releasing peptide-producing cells in the area postrema of postnatal rats
    Fujiwara K, Usui K, Yashiro T, Inoue K
    Regulatory Peptides 145 33-36 2008年
  • The in vivo correlation between c-Fos expression and corticotroph stimulation by adrenocorticotrophic hormone secretagogues in the rat anterior pituitary gland
    Takigami S, Fujiwara K, Kikuchi M, Yashiro T
    Cell and Tissue Research 331 589-594 2008年
  • Estrogen suppresses retinaldehyde dehydrogenase 1 expression in the anterior pituitary glands of female rats
    Fujiwara K, Davaadash B, Kikuchi M, Takigami S, Yashiro T
    Endocrine Journal 55(1) 91-96 2008年
  • Immunohistochemical observation of connexin 43 throughout anterior pituitary gland using a transgenic rat with green fluorescent protein-expressing folliculo-stellate cells
    Horiguchi K, Fujiwara K, Kouki T, Kikuchi M, Yashiro T
    Anatomical Science International 2008年
  • Reduction of retinaldehyde dehydrogenase 1 expression and production in the estrogen induced prolactinoma of rat
    Fujiwara K, Davaadash B, Yatabe M, Kikuchi M, Horiguchi K, Kusumoto K, Kouki T, Yashiro T
    Medical Molecular Morphology 41(3) 126-131 2008年
  • Spatio-temporal relation between cadherin switching and cytogenesis of hormone-producing cells in the developing rat adenohypophsis.
    Kikuchi M, Yatabe M, Fujiwara K, Horiguchi K, Kusumoto K, Kouki T, Sakamoto A, Yashiro T
    Anatomical Science International 84 155 2009年
  • Blockage of PrRP attenuates MPTP-induced toxicity in mice.
    Sun B, Mochiduki A, Nakamura K, Yokoyama K, Adachi S, Fujiwara K, Matsumoto H, Inoue K
    Peptides 30 1267-1275 2009年
  • Estrogen receptor alpha regulates retinaldehyde dehydrogenase 1 expression in rat anterior pituitary cells.
    Fujiwara K, Kikuchi M, Horiguchi K, Kusumoto K, Kouki T, Kawanishi K, Yashiro T
    Endocrine Journal 56(8) 963-973 2009年
  • Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.
    Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T
    Cell Metabolism 10 355-365 2009年
  • Living-cell imaging of transgenic (S100b-GFP) rat anterior pituitary cells in primary culture reveals novel characteristics of folliculo-stellate cells.
    Horiguchi K, Kikuchi M, Kusumoto K, Fujiwara K, Kouki T, Kawanishi K, Yashiro T
    Journal of Endocrinology 204(2) 115-123 2010年
  • Effect of E-cadherin Expression on Hormone Production in Rat Anterior Pituitary Lactotrophs In Vitro.
    Kusumoto K, Kikuchi M, Fujiwara K, Horiguchi K, Kouki T, Kawanishi K, Yashiro T
    Acta Histochemica et Cytochemica 43(2) 83-88 2010年
  • Long-term infusion of brain-derived neurotrophic factor reduces food intake and body weight via a corticotropin-releasing hormone pathway in the paraventricular nucleus of the hypothalamus.
    Toriya M, Maekawa F, Maejima Y, Onaka T, Fujiwara K, Nakagawa T, Nakata M, Yada T
    Journal of Neuroendocrinology 22(987-995) 2010年

受賞

  • 2008年 日本内分泌病理学会 最優秀賞
  • 2007年 日本下垂体研究会 特別優秀発表賞
受賞を全て表示する
受賞閉じる
  • 2008年 日本内分泌病理学会 最優秀賞
  • 2007年 日本下垂体研究会 特別優秀発表賞

外部的資金

  • 下垂体前葉内で産生される新規分泌因子を介した細胞間コミュニケーションの解析
    文部科学省:科学研究費補助金(基盤研究(C))
    研究期間 :2014年 - 2016年 代表者 : 藤原 研
  • 下垂体前葉細胞の機能調節に関わる濾胞星状細胞が産生する新規分泌因子の機能解析
    文部科学省:科学研究費補助金(若手研究(B))
    研究期間 :2012年 - 2013年 代表者 : 藤原 研
  • 下垂体ホルモン産生細胞の機能亢進・過形成・腫瘍化におけるレチノイン酸合成の動態
    文部科学省:科学研究費補助金(若手研究(B))
    研究期間 :2008年 - 2010年 代表者 : 藤原 研
  • 下垂体前葉のレチノイン酸合成酵素の同定と新たな細胞機能調節メカニズムの解明
    文部科学省:科学研究費補助金(若手研究(B))
    研究期間 :2006年 - 2007年 代表者 : 藤原 研
外部資金採択状況を全て表示する
外部資金採択状況閉じる
  • 下垂体前葉内で産生される新規分泌因子を介した細胞間コミュニケーションの解析
    文部科学省:科学研究費補助金(基盤研究(C))
    研究期間 :2014年 - 2016年 代表者 : 藤原 研
  • 下垂体前葉細胞の機能調節に関わる濾胞星状細胞が産生する新規分泌因子の機能解析
    文部科学省:科学研究費補助金(若手研究(B))
    研究期間 :2012年 - 2013年 代表者 : 藤原 研
  • 下垂体ホルモン産生細胞の機能亢進・過形成・腫瘍化におけるレチノイン酸合成の動態
    文部科学省:科学研究費補助金(若手研究(B))
    研究期間 :2008年 - 2010年 代表者 : 藤原 研
  • 下垂体前葉のレチノイン酸合成酵素の同定と新たな細胞機能調節メカニズムの解明
    文部科学省:科学研究費補助金(若手研究(B))
    研究期間 :2006年 - 2007年 代表者 : 藤原 研


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