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中田 正範 ナカタ マサノリ

所属部署名生理学講座統合生理学部門
職名准教授ホームページURLhttp://www.jichi.ac.jp/physio2/default.htm

プロフィール

プロフィール

    視床下部によるエネルギー代謝、骨代謝、血圧調節機構を研究しています。

研究キーワード

    包括脳ネットワーク, 脳科学, 糖尿病学, 生理学, 摂食調節

研究分野

  • 基礎医学 / 生理学一般
  • 内科系臨床医学 / 代謝学
  • 内科系臨床医学 / 内分泌学

経歴

  • 2007年03月
    -
    現在
    自治医科大学(准教授)

所属学協会

  • 日本糖尿病学
  • 日本生理学
  • 日本分子生物学
  • 日本癌学会
所属学協会を全て表示する
所属学協会閉じる
  • 日本糖尿病学
  • 日本生理学
  • 日本分子生物学
  • 日本癌学会

学位

  • 医学博士

研究活動

論文

  • Glucose and insulin induce Ca2+ signaling in nesfatin-1 neurons in the hypothalamic paraventricular nucleus.
    Gantulga D, Maejima Y, Nakata M, Yada T
    Biochemical and biophysical research communications 420 811-815 2012年04月
  • Nesfatin-1 enhances glucose-induced insulin secretion by promoting Ca(2+) influx through L-type channels in mouse islet β-cells.
    Nakata M, Manaka K, Yamamoto S, Mori M, Yada T
    Endocrine journal 58(4) 305-313 2011年
  • PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure.
    Cao Y, Nakata M, Okamoto S, Takano E, Yada T, Minokoshi Y, Hirata Y, Nakajima K, Iskandar K, Hayashi Y, Ogawa W, Barsh GS, Hosoda H, Kangawa K, Itoh H, Noda T, Kasuga M, Nakae J
    PloS one 6 e18324 2011年
  • Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity.
    Nakata M, Shintani N, Hashimoto H, Baba A, Yada T
    Journal of molecular neuroscience : MN 42 404-410 2010年11月
  • Stressor-responsive central nesfatin-1 activates corticotropin-releasing hormone, noradrenaline and serotonin neurons and evokes hypothalamic-pituitary-adrenal axis.
    Yoshida N, Maejima Y, Sedbazar U, Ando A, Kurita H, Damdindorj B, Takano E, Gantulga D, Iwasaki Y, Kurashina T, Onaka T, Dezaki K, Nakata M, Mori M, Yada T
    Aging 2 775-784 2010年11月
  • Voltage-dependent metabolic regulation of Kv2.1 channels in pancreatic beta-cells.
    Yoshida M, Nakata M, Yamato S, Dezaki K, Sugawara H, Ishikawa SE, Kawakami M, Yada T, Kakei M
    Biochemical and biophysical research communications 396(2) 304-309 2010年05月
  • PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake.
    Iskandar K, Cao Y, Hayashi Y, Nakata M, Takano E, Yada T, Zhang C, Ogawa W, Oki M, Chua S Jr, Itoh H, Noda T, Kasuga M, Nakae J
    American journal of physiology. Endocrinology and metabolism 298 E787-98 2010年04月
  • Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.
    Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T
    Cell metabolism 10 355-365 2009年11月
  • Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic beta-cells.
    Yoshida M, Dezaki K, Yamato S, Aoki A, Sugawara H, Toyoshima H, Ishikawa SE, Kawakami M, Nakata M, Yada T, Kakei M
    FEBS letters 583(13) 2225-2230 2009年07月
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
論文等(論文)を全て表示する
論文等(論文)閉じる
  • Glucose and insulin induce Ca2+ signaling in nesfatin-1 neurons in the hypothalamic paraventricular nucleus.
    Gantulga D, Maejima Y, Nakata M, Yada T
    Biochemical and biophysical research communications 420 811-815 2012年04月
  • Nesfatin-1 enhances glucose-induced insulin secretion by promoting Ca(2+) influx through L-type channels in mouse islet β-cells.
    Nakata M, Manaka K, Yamamoto S, Mori M, Yada T
    Endocrine journal 58(4) 305-313 2011年
  • PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure.
    Cao Y, Nakata M, Okamoto S, Takano E, Yada T, Minokoshi Y, Hirata Y, Nakajima K, Iskandar K, Hayashi Y, Ogawa W, Barsh GS, Hosoda H, Kangawa K, Itoh H, Noda T, Kasuga M, Nakae J
    PloS one 6 e18324 2011年
  • Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity.
    Nakata M, Shintani N, Hashimoto H, Baba A, Yada T
    Journal of molecular neuroscience : MN 42 404-410 2010年11月
  • Stressor-responsive central nesfatin-1 activates corticotropin-releasing hormone, noradrenaline and serotonin neurons and evokes hypothalamic-pituitary-adrenal axis.
    Yoshida N, Maejima Y, Sedbazar U, Ando A, Kurita H, Damdindorj B, Takano E, Gantulga D, Iwasaki Y, Kurashina T, Onaka T, Dezaki K, Nakata M, Mori M, Yada T
    Aging 2 775-784 2010年11月
  • Voltage-dependent metabolic regulation of Kv2.1 channels in pancreatic beta-cells.
    Yoshida M, Nakata M, Yamato S, Dezaki K, Sugawara H, Ishikawa SE, Kawakami M, Yada T, Kakei M
    Biochemical and biophysical research communications 396(2) 304-309 2010年05月
  • PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake.
    Iskandar K, Cao Y, Hayashi Y, Nakata M, Takano E, Yada T, Zhang C, Ogawa W, Oki M, Chua S Jr, Itoh H, Noda T, Kasuga M, Nakae J
    American journal of physiology. Endocrinology and metabolism 298 E787-98 2010年04月
  • Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.
    Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T
    Cell metabolism 10 355-365 2009年11月
  • Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic beta-cells.
    Yoshida M, Dezaki K, Yamato S, Aoki A, Sugawara H, Toyoshima H, Ishikawa SE, Kawakami M, Nakata M, Yada T, Kakei M
    FEBS letters 583(13) 2225-2230 2009年07月
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年
  • Betatrophin expression is promoted in obese hyperinsulinemic type 2 but not type 1 diabetic mice
    Li EnXu;Nakata Masanori;Shinozaki Atsumi;Yang Yifei;Zhang Boyang;Yada Toshihiko
    Endocrine Journal 0(0) 2016年

外部的資金

  • 膵再生
  • 骨代謝
    研究期間 :2009年
  • エネルギー代謝調節
  • 血管機能調節(血圧・糖尿病血管合併症)
外部資金採択状況を全て表示する
外部資金採択状況閉じる
  • 膵再生
  • 骨代謝
    研究期間 :2009年
  • エネルギー代謝調節
  • 血管機能調節(血圧・糖尿病血管合併症)


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