詳細検索はこちら

武藤 弘行 ムトウ ヒロユキ

所属部署名情報センター
職名教授ホームページURL

プロフィール

研究キーワード

    胃癌

研究分野

  • 内科系臨床医学 / 消化器内科学

学位

  • 医学博士

研究活動

論文

  • SOX9 is expressed in normal stomach, intestinal metaplasia, and gastric carcinoma in humans.
    Sashikawa Kimura M, Mutoh H, Sugano K
    Journal of gastroenterology 46(11) 1292-1299 2011年11月
  • Cell lineage dynamics in the process leading to intestinal metaplasia.
    Sakamoto H, Mutoh H, Hayakawa H, Sashikawa M, Sugano K
    Journal of gastroenterology 46(5) 620-628 2011年05月
  • Sox2 expression is maintained while gastric phenotype is completely lost in Cdx2-induced intestinal metaplastic mucosa.
    Mutoh H, Sashikawa M, Sugano K
    Differentiation; research in biological diversity 81(2) 92-98 2011年02月
  • Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach.
    Sakamoto H, Mutoh H, Sugano K
    Scandinavian journal of gastroenterology 45(11) 1273-1280 2010年11月
  • Monocyte chemoattractant protein-1 is generated via TGF-beta by myofibroblasts in gastric intestinal metaplasia and carcinoma without H. pylori infection.
    Mutoh H, Sashikawa M, Hayakawa H, Sugano K
    Cancer science 101(8) 1783-1789 2010年08月
  • Direct repression of Sonic Hedgehog expression in the stomach by Cdx2 leads to intestinal transformation.
    Mutoh H, Hayakawa H, Sashikawa M, Sakamoto H, Sugano K
    The Biochemical journal 427(3) 423-434 2010年04月
  • Intestinal metaplasia in gallbladder correlates with high amylase levels in bile in patients with a morphologically normal pancreaticobiliary duct.
    Sakamoto H, Mutoh H, Ido K, Satoh S, Kumagai M, Hayakawa H, Tamada K, Sugano K
    Human pathology 40 1762-1767 2009年12月
  • Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach.
    Mutoh H, Hayakawa H, Sakamoto H, Sashikawa M, Sugano K
    The FEBS journal 276(20) 5821-5831 2009年10月
  • Homeobox protein CDX2 reduces Cox-2 transcription by inactivating the DNA-binding capacity of nuclear factor-kappaB.
    Mutoh H, Hayakawa H, Sakamoto H, Sugano K
    Journal of gastroenterology 42(9) 719-729 2007年09月
  • A close relationship between intestinal metaplasia and Cdx2 expression in human gallbladders with cholelithiasis.
    Sakamoto H, Mutoh H, Ido K, Satoh K, Hayakawa H, Sugano K
    Human pathology 38 66-71 2007年01月
論文等(論文)を全て表示する
論文等(論文)閉じる
  • SOX9 is expressed in normal stomach, intestinal metaplasia, and gastric carcinoma in humans.
    Sashikawa Kimura M, Mutoh H, Sugano K
    Journal of gastroenterology 46(11) 1292-1299 2011年11月
  • Cell lineage dynamics in the process leading to intestinal metaplasia.
    Sakamoto H, Mutoh H, Hayakawa H, Sashikawa M, Sugano K
    Journal of gastroenterology 46(5) 620-628 2011年05月
  • Sox2 expression is maintained while gastric phenotype is completely lost in Cdx2-induced intestinal metaplastic mucosa.
    Mutoh H, Sashikawa M, Sugano K
    Differentiation; research in biological diversity 81(2) 92-98 2011年02月
  • Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach.
    Sakamoto H, Mutoh H, Sugano K
    Scandinavian journal of gastroenterology 45(11) 1273-1280 2010年11月
  • Monocyte chemoattractant protein-1 is generated via TGF-beta by myofibroblasts in gastric intestinal metaplasia and carcinoma without H. pylori infection.
    Mutoh H, Sashikawa M, Hayakawa H, Sugano K
    Cancer science 101(8) 1783-1789 2010年08月
  • Direct repression of Sonic Hedgehog expression in the stomach by Cdx2 leads to intestinal transformation.
    Mutoh H, Hayakawa H, Sashikawa M, Sakamoto H, Sugano K
    The Biochemical journal 427(3) 423-434 2010年04月
  • Intestinal metaplasia in gallbladder correlates with high amylase levels in bile in patients with a morphologically normal pancreaticobiliary duct.
    Sakamoto H, Mutoh H, Ido K, Satoh S, Kumagai M, Hayakawa H, Tamada K, Sugano K
    Human pathology 40 1762-1767 2009年12月
  • Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach.
    Mutoh H, Hayakawa H, Sakamoto H, Sashikawa M, Sugano K
    The FEBS journal 276(20) 5821-5831 2009年10月
  • Homeobox protein CDX2 reduces Cox-2 transcription by inactivating the DNA-binding capacity of nuclear factor-kappaB.
    Mutoh H, Hayakawa H, Sakamoto H, Sugano K
    Journal of gastroenterology 42(9) 719-729 2007年09月
  • A close relationship between intestinal metaplasia and Cdx2 expression in human gallbladders with cholelithiasis.
    Sakamoto H, Mutoh H, Ido K, Satoh K, Hayakawa H, Sugano K
    Human pathology 38 66-71 2007年01月
  • Differential gene expression between flat adenoma and normal mucosa in the colon in a microarray analysis.
    Kita H, Hikichi Y, Hikami K, Tsuneyama K, Cui ZG, Osawa H, Ohnishi H, Mutoh H, Hoshino H, Bowlus CL, Yamamoto H, Sugano K
    Journal of gastroenterology 41(11) 1053-1063 2006年11月
  • The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1.
    Mutoh H, Sakamoto H, Hayakawa H, Arao Y, Satoh K, Nokubi M, Sugano K
    Differentiation; research in biological diversity 74 313-321 2006年07月
  • Helicobacter pylori eradication induces marked increase in H+/K+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa.
    Osawa H, Kita H, Ohnishi H, Hoshino H, Mutoh H, Ishino Y, Watanabe E, Satoh K, Sugano K
    Gut 55 152-157 2006年02月
  • [Expression of transcription factor in Barrett's esophagus].
    Mutoh H
    Nihon rinsho. Japanese journal of clinical medicine 63 1367-1371 2005年08月
  • [Cdx2 and gastric carcinoma].
    Mutoh H
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 102 986-993 2005年08月
  • Histamine-2 receptor expression in gastric mucosa before and after Helicobacter pylori cure.
    Osawa H, Kita H, Ohnishi H, Mutoh H, Ishino Y, Satoh K, Sugano K
    Alimentary pharmacology & therapeutics 21 Suppl 2 92-98 2005年06月
  • Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.
    Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K
    Gut 54 33-39 2005年01月
  • Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine.
    Mutoh H, Satoh K, Kita H, Sakamoto H, Hayakawa H, Yamamoto H, Isoda N, Tamada K, Ido K, Sugano K
    The International journal of developmental biology 49 867-871 2005年
  • Gastrointestinal angiodysplasia in a patient with type 2 von Willebrand's disease and analysis of exon 28 of the von Willebrand factor gene.
    Satoh Y, Kita H, Kihira K, Mutoh H, Osawa H, Satoh K, Ido K, Sakata Y, Sugano K
    The American journal of gastroenterology 99 2495-2498 2004年12月
  • Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.
    Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K
    Cancer research 64 7740-7747 2004年11月
  • Cdx1 induced intestinal metaplasia in the transgenic mouse stomach: comparative study with Cdx2 transgenic mice.
    Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K
    Gut 53 1416-1423 2004年10月
  • Aberrant expression of CDX2 in the metaplastic epithelium and inflammatory mucosa of the gallbladder.
    Osawa H, Kita H, Satoh K, Ohnishi H, Kaneko Y, Mutoh H, Tamada K, Ido K, Sugano K
    The American journal of surgical pathology 28 1253-1254 2004年09月
  • Change in apoptosis in the gastric surface epithelium and glands after eradication of Helicobacter pylori.
    Satoh K, Kawata H, Tokumaru K, Kumakura Y, Ishino Y, Kawakami S, Inoue K, Kojima T, Satoh Y, Mutoh H, Kihira K, Sugano K
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 35 78-84 2003年02月
  • Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosa.
    Eda A, Osawa H, Satoh K, Yanaka I, Kihira K, Ishino Y, Mutoh H, Sugano K
    Journal of gastroenterology 38(1) 14-22 2003年
  • Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori.
    Satoh K, Mutoh H, Eda A, Yanaka I, Osawa H, Honda S, Kawata H, Kihira K, Sugano K
    Helicobacter 7 192-198 2002年06月
  • Conversion of gastric mucosa to intestinal metaplasia in Cdx2-expressing transgenic mice.
    Mutoh H, Hakamata Y, Sato K, Eda A, Yanaka I, Honda S, Osawa H, Kaneko Y, Sugano K
    Biochemical and biophysical research communications 294(2) 470-479 2002年06月
  • Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD.
    Ratineau C, Petry MW, Mutoh H, Leiter AB
    The Journal of biological chemistry 277(11) 8847-8853 2002年03月
  • [H. pylori and para-neuron secretion (gastrin, somatostatin, histamine)].
    Mutoh H, Sugano K
    Nihon rinsho. Japanese journal of clinical medicine 60 Suppl 2 252-255 2002年02月
  • [Duodenal ulcer].
    Mutoh H, Sugano K
    Nihon rinsho. Japanese journal of clinical medicine 60 Suppl 1 151-160 2002年01月
  • Expression of homeobox gene CDX2 precedes that of CDX1 during the progression of intestinal metaplasia.
    Eda A, Osawa H, Yanaka I, Satoh K, Mutoh H, Kihira K, Sugano K
    Journal of gastroenterology 37 94-100 2002年
  • Auxiliary partial liver grafting in rats: effect of host hepatectomy on graft regeneration, and review of literature on surgical technique.
    Wang J, Tahara K, Hakamata Y, Mutoh H, Murakami T, Takahashi M, Kusama M, Kobayashi E
    Microsurgery 22 371-377 2002年
  • p53 expression in the gastric mucosa before and after eradication of Helicobacter pylori.
    Satoh K, Kihira K, Kawata H, Tokumaru K, Kumakura Y, Ishino Y, Kawakami S, Inoue K, Kojima T, Satoh Y, Mutoh H, Sugano K
    Helicobacter 6 31-36 2001年03月
  • Review article: transcriptional events controlling the terminal differentiation of intestinal endocrine cells.
    Mutoh H, Ratineau C, Ray S, Leiter AB
    Alimentary pharmacology & therapeutics 14 Suppl 1 170-175 2000年04月
  • The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells.
    Mutoh H, Naya FJ, Tsai MJ, Leiter AB
    Genes & development 12 820-830 1998年03月
  • Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice.
    Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai MJ
    Genes & development 11(18) 2323-2334 1997年09月
  • The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression.
    Mutoh H, Fung BP, Naya FJ, Tsai MJ, Nishitani J, Leiter AB
    Proceedings of the National Academy of Sciences of the United States of America 94(8) 3560-3564 1997年04月
  • Structure and regulation of platelet activating factor receptor gene.
    Shimizu T, Mutoh H
    Advances in experimental medicine and biology 407 197-204 1997年
  • Tissue-specific response of the human platelet-activating factor receptor gene to retinoic acid and thyroid hormone by alternative promoter usage.
    Mutoh H, Fukuda T, Kitamaoto T, Masushige S, Sasaki H, Shimizu T, Kato S
    Proceedings of the National Academy of Sciences of the United States of America 93(2) 774-779 1996年01月
  • Platelet-activating factor receptor. Gene structure and tissue-specific regulation.
    Shimizu T, Mutoh H, Kato S
    Advances in experimental medicine and biology 416 79-84 1996年
  • Up-regulation of the intracellular Ca2+ signaling and mRNA expression of platelet-activating factor receptor by estradiol in human uterine endometrial cells.
    Sato S, Kume K, Takan T, Mutoh H, Taketani Y, Shimizu T
    Advances in experimental medicine and biology 416 95-100 1996年
  • Relationships between metal ions and oxygen free radicals in ethanol-induced damage to cultured rat gastric mucosal cells.
    Mutoh H, Hiraishi H, Ota S, Terano A, Ogura K, Ivey KJ, Sugimoto T
    Digestive diseases and sciences 40 2704-2711 1995年12月
  • Platelet-activating factor receptor.
    Izumi T, Takano T, Bito H, Nakamura M, Mutoh H, Honda Z, Shinizu T
    Journal of lipid mediators and cell signalling 12 429-442 1995年10月
  • Amino-acid sequence and tissue distribution of guinea-pig leukotriene A4 hydrolase.
    Minami M, Mutoh H, Ohishi N, Honda Z, Bito H, Shimizu T
    Gene 161(2) 249-251 1995年08月
  • Adaptive cytoprotection in cultured rat gastric mucus-producing cells. Role of mucus and prostaglandin synthesis.
    Mutoh H, Ota S, Hiraishi H, Ivey KJ, Terano A, Sugimoto T
    Digestive diseases and sciences 40 872-878 1995年04月
  • Regulation and signal transduction of PAF receptor.
    Izumi T, Honda Z, Mutoh H, Kume K, Shimizu T
    Advances in prostaglandin, thromboxane, and leukotriene research 23 461-466 1995年
  • Positive and negative regulations of human platelet-activating factor receptor transcript 2 (tissue-type) by estrogen and TGF-beta 1.
    Mutoh H, Kume K, Sato S, Kato S, Shimizu T
    Biochemical and biophysical research communications 205(2) 1130-1136 1994年12月
  • Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-kappa B.
    Mutoh H, Ishii S, Izumi T, Kato S, Shimizu T
    Biochemical and biophysical research communications 205(2) 1137-1142 1994年12月
  • Growth regulation of rabbit gastric epithelial cells and protooncogene expression.
    Yoshiura K, Ota S, Terano A, Takahashi M, Hata Y, Kawabe T, Mutoh H, Hiraishi H, Nakata R, Okano K
    Digestive diseases and sciences 39 1454-1463 1994年07月
  • P2 purinergic receptor regulation of mucus glycoprotein secretion by rabbit gastric mucous cells in a primary culture.
    Ota S, Yoshiura K, Takahashi M, Hata Y, Kohmoto O, Kawabe T, Shimada T, Hiraishi H, Mutoh H, Terano A
    Gastroenterology 106 1485-1492 1994年06月
  • Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione.
    Hiraishi H, Terano A, Ota S, Mutoh H, Sugimoto T, Harada T, Razandi M, Ivey KJ
    Gastroenterology 106 1199-1207 1994年05月
  • Churg-Strauss syndrome (allergic granulomatous angiitis) with multiple perforating ulcers of the small intestine, multiple ulcers of the colon, and mononeuritis multiplex.
    Kurita M, Niwa Y, Hamada E, Hata Y, Oshima M, Mutoh H, Shiina S, Nakata R, Ota S, Terano A
    Journal of gastroenterology 29(2) 208-213 1994年04月
  • Roles of Ca2+ and protein kinase C in regulation of prostaglandin E2 release by cultured rabbit gastric epithelial cells.
    Ota S, Hata Y, Terano A, Yoshiura K, Hiraishi H, Kawabe T, Mutoh H, Shiina S, Sugimoto T
    Digestive diseases and sciences 38 1426-1434 1993年08月
  • Two different promoters direct expression of two distinct forms of mRNAs of human platelet-activating factor receptor.
    Mutoh H, Bito H, Minami M, Nakamura M, Honda Z, Izumi T, Nakata R, Kurachi Y, Terano A, Shimizu T
    FEBS letters 322(2) 129-134 1993年05月
  • Role for mucous glycoprotein in protecting cultured rat gastric mucosal cells against toxic oxygen metabolites.
    Hiraishi H, Terano A, Ota S, Mutoh H, Sugimoto T, Harada T, Razandi M, Ivey KJ
    The Journal of laboratory and clinical medicine 121 570-578 1993年04月
  • Gastric cytoprotection: morphological perspectives.
    Terano A, Ota S, Hiraishi H, Mutoh H
    Acta pathologica japonica 43 2-10 1993年01月
  • Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart.
    Sugimoto T, Tsuchimochi H, McGregor CG, Mutoh H, Shimizu T, Kurachi Y
    Biochemical and biophysical research communications 189(2) 617-624 1992年12月
  • Three types of Gi alpha protein of the guinea-pig lung: cDNA cloning and analysis of their tissue distribution.
    Sakanaka C, Izumi T, Nakamura M, Honda Z, Watanabe T, Minami M, Mutoh H, Bito H, Seyama Y, Ui M
    Biochimica et biophysica acta 1175 61-66 1992年12月
  • Leukotriene A4 hydrolase, a bifunctional enzyme. Distinction of leukotriene A4 hydrolase and aminopeptidase activities by site-directed mutagenesis at Glu-297.
    Minami M, Bito H, Ohishi N, Tsuge H, Miyano M, Mori M, Wada H, Mutoh H, Shimada S, Izumi T
    FEBS letters 309(3) 353-357 1992年09月
  • The effects of acid secretagogues on protective agents of gastric cells from adult rabbits in vitro.
    Ota S, Hata Y, Hiraishi H, Mutoh H, Terano A, Sugimoto T
    Journal of clinical gastroenterology 14 Suppl 1 S156-61 1992年
  • Antioxidant defenses of cultured gastric cells against oxygen metabolites: role of GSH redox cycle and endogenous catalase.
    Hiraishi H, Terano A, Ota S, Mutoh H, Sugimoto T, Razandi M, Ivey KJ
    The American journal of physiology 261 G921-8 1991年12月
  • Oxygen metabolites stimulate mucous glycoprotein secretion from cultured rat gastric mucous cells.
    Hiraishi H, Terano A, Ota S, Mutoh H, Sugimoto T, Razandi M, Ivey KJ
    The American journal of physiology 261 G662-8 1991年10月
  • Molecular cloning and expression of platelet-activating factor receptor from human leukocytes.
    Nakamura M, Honda Z, Izumi T, Sakanaka C, Mutoh H, Minami M, Bito H, Seyama Y, Matsumoto T, Noma M
    The Journal of biological chemistry 266 20400-20405 1991年10月
  • The effect of cimetidine on adaptive cytoprotection by mild irritant dose of HCl in the rat gastric mucosa.
    Ota S, Hiraishi H, Terano A, Mutoh H, Hata Y, Ivey KJ, Sugimoto T
    Japanese journal of pharmacology 57(1) 63-69 1991年09月
  • Reduced glutathione protects cultured gastric mucosal cells from suckling rats against acid.
    Mutoh H, Ota S, Hiraishi H, Ivey KJ, Terano A, Sugimoto T
    The American journal of physiology 261 G65-70 1991年07月
  • Role for iron in reactive oxygen species-mediated cytotoxicity to cultured rat gastric mucosal cells.
    Hiraishi H, Terano A, Ota S, Mutoh H, Razandi M, Sugimoto T, Ivey KJ
    The American journal of physiology 260 G556-63 1991年04月
  • Protective effect of tauroursodeoxycholate against chenodeoxycholate-induced damage to cultured rabbit gastric cells.
    Ota S, Tsukahara H, Terano A, Hata Y, Hiraishi H, Mutoh H, Sugimoto T
    Digestive diseases and sciences 36 409-416 1991年04月
  • Multiple-needle insertion method in percutaneous ethanol injection therapy for liver neoplasms.
    Shiina S, Hata Y, Niwa Y, Komatsu Y, Tanaka T, Yoshiura K, Hamada E, Ohshima M, Mutoh H, Kurita M
    Gastroenterologia Japonica 26 47-50 1991年02月
  • Characterization of a newly established cell line (JR-St) derived from human gastric signet ring cell cancer, producing tumor markers.
    Terano A, Nakada R, Mutoh H, Hiraishi H, Ota S, Shiina S, Shimada T, Itoh Y, Kimura K, Shiga J
    Gastroenterologia Japonica 26 7-13 1991年02月
  • Tetraprenylacetone promotes healing process of ethanol-induced gastric damage in the rat.
    Terano A, Shiga J, Mutoh H, Hiraishi H, Shiina S, Kurita M, Ota S, Itoh Y, Sugimoto T
    Japanese journal of pharmacology 55(1) 115-120 1991年01月
  • Leukotriene A4 hydrolase is a zinc-containing aminopeptidase.
    Minami M, Ohishi N, Mutoh H, Izumi T, Bito H, Wada H, Seyama Y, Toh H, Shimizu T
    Biochemical and biophysical research communications 173(2) 620-626 1990年12月
  • Ultrasound-guided percutaneous injection of ethanolamine oleate for hypersplenism. An experimental study in dogs.
    Shina S, Aoyama H, Shiratori Y, Mutoh H, Kurita M, Ota S, Terano A, Sugimoto T
    Investigative radiology 25 651-657 1990年06月
  • Protective role of intracellular glutathione against ethanol-induced damage in cultured rat gastric mucosal cells.
    Mutoh H, Hiraishi H, Ota S, Yoshida H, Ivey KJ, Terano A, Sugimoto T
    Gastroenterology 98 1452-1459 1990年06月
  • Role of oxygen radicals in ethanol-induced damage to cultured gastric mucosal cells.
    Mutoh H, Hiraishi H, Ota S, Ivey KJ, Terano A, Sugimoto T
    The American journal of physiology 258 G603-9 1990年04月
  • Effect of adenosine and adenosine analogs on [14C]aminopyrine accumulation by rabbit parietal cells.
    Ota S, Hiraishi H, Terano A, Mutoh H, Kurachi Y, Shimada T, Ivey KJ, Sugimoto T
    Digestive diseases and sciences 34 1882-1889 1989年12月
  • Splenic ablation by percutaneous injection of ethanolamine oleate in dogs: a possible therapy for hypersplenism.
    Shiina S, Aoyama H, Shiratori Y, Hata Y, Niwa Y, Komatsu Y, Mutoh H, Kurita M, Nakata R, Shimada T
    Gastroenterologia Japonica 24 740 1989年12月
  • [Establishment and characterization of a tumor marker producing cell line (JR-1) derived from a gastric scirrhous cancer].
    Terano A, Nakada R, Mutoh H, Hiraishi H, Ota S, Kimura K, Aoyama H, Sugimoto T, Shiga J, Itoh Y
    Human cell : official journal of Human Cell Research Society 2 307-309 1989年09月
  • Establishment of a new cell line derived from human gastric adenocarcinoma, producing tumor markers.
    Terano A, Nakada R, Hiraishi H, Ota S, Mutoh H, Shimada T, Shiina S, Itoh Y, Shiga J, Sugimoto T
    Gastroenterologia Japonica 24 219 1989年04月
  • Effect of tetraprenylacetone, a novel anti-ulcer agent, on healing process of ethanol-induced gastric injury in rat.
    Terano A, Shiga J, Ota S, Hiraishi H, Mutoh H, Sugimoto T
    Gastroenterologia Japonica 24 81 1989年02月
  • Do mild irritants protect surface epithelial cells of gastric mucosa against ethanol-induced damage in rat? An ultrastructural study of adaptive cytoprotection.
    Terano A, Shiga J, Hiraishi H, Ota S, Mutoh H, Sugimoto T
    Gastroenterologia Japonica 24 80 1989年02月

外部的資金

  • 胃腸上皮化生粘膜における腸粘膜上皮幹細胞の発現
    :基盤研究C
    研究期間 :2011年 - 2014年
  • 感染発がんエンハンサーとしての宿主応答とその制御
    :新学術領域
    研究期間 :2010年 - 2015年
  • 胃癌の前癌病変である腸上皮化生粘膜における転写因子Cdx2とCdx1の関係
    :基盤研究C
    研究期間 :2009年 - 2012年 代表者 : 武藤
  • Shhの腸上皮化生粘膜における低下の原因
    :基盤研究C
    研究期間 :2009年 - 2012年 代表者 : 武藤
  • 小腸粘膜上皮細胞の分化誘導における転写因子Math1とCdx2の関係
    :基盤研究C
    研究期間 :2006年 - 2008年
  • 腸上皮化生の発生とその制御に関する研究
    :基盤研究B
    研究期間 :2006年 - 2008年
  • 腸上皮化生からの分化型胃癌の発癌のメカニズムの解明
    :基盤研究C
    研究期間 :2004年 - 2006年
  • 腸上皮化生から分化型胃癌発生の分子機構の解明
    :基盤研究B
    研究期間 :2004年 - 2006年
  • 胃粘膜腸上皮化生から胃分化型腺癌への進展の分子生物学的メカニズムの解明
    :萌芽研究
    研究期間 :2002年 - 2004年
  • 転写因子Cdx2の腸管粘膜での転写制御及び胃粘膜腸上皮化生における発現誘導の解析
    :基盤研究C
    研究期間 :2002年 - 2004年 代表者 : 武藤
外部資金採択状況を全て表示する
外部資金採択状況閉じる
  • 胃腸上皮化生粘膜における腸粘膜上皮幹細胞の発現
    :基盤研究C
    研究期間 :2011年 - 2014年
  • 感染発がんエンハンサーとしての宿主応答とその制御
    :新学術領域
    研究期間 :2010年 - 2015年
  • 胃癌の前癌病変である腸上皮化生粘膜における転写因子Cdx2とCdx1の関係
    :基盤研究C
    研究期間 :2009年 - 2012年 代表者 : 武藤
  • Shhの腸上皮化生粘膜における低下の原因
    :基盤研究C
    研究期間 :2009年 - 2012年 代表者 : 武藤
  • 小腸粘膜上皮細胞の分化誘導における転写因子Math1とCdx2の関係
    :基盤研究C
    研究期間 :2006年 - 2008年
  • 腸上皮化生の発生とその制御に関する研究
    :基盤研究B
    研究期間 :2006年 - 2008年
  • 腸上皮化生からの分化型胃癌の発癌のメカニズムの解明
    :基盤研究C
    研究期間 :2004年 - 2006年
  • 腸上皮化生から分化型胃癌発生の分子機構の解明
    :基盤研究B
    研究期間 :2004年 - 2006年
  • 胃粘膜腸上皮化生から胃分化型腺癌への進展の分子生物学的メカニズムの解明
    :萌芽研究
    研究期間 :2002年 - 2004年
  • 転写因子Cdx2の腸管粘膜での転写制御及び胃粘膜腸上皮化生における発現誘導の解析
    :基盤研究C
    研究期間 :2002年 - 2004年 代表者 : 武藤
  • 転写因子Cdx1、Cdx2による胃の腸上皮化生の作成と遺伝子解析
    :基盤研究B
    研究期間 :2001年 - 2003年
  • 転写因子BETA2によるセクレチン分泌細胞の分化と細胞周期
    :基盤研究B
    研究期間 :2000年 - 2002年 代表者 : 武藤


Copyright © MEDIA FUSION Co.,Ltd. All rights reserved.