Researchers Database

maekawa takeo

    Dermatology Associate Professor
Last Updated :2021/12/08

Researcher Information


Research funding number

  • 20332603

J-Global ID

Research Interests

  • 創傷治癒   褥瘡   皮膚悪性腫瘍   皮膚外科   下肢静脈瘤   セレクチン   beta7 integrin   悪性黒色腫   細胞接着因子   インテグリン   

Research Areas

  • Life sciences / Dermatology

Academic & Professional Experience

  • 2015/11 - Today  Jichi Medical University皮膚科准教授
  • 2010 - 2015/10  Jichi Medical University皮膚科講師
  • 2006 - 2010  三楽病院皮膚科科長
  • 2003 - 2006  The University of TokyoFaculty of Medicine University Hospital助手
  • 2001 - 2003  虎ノ門病院皮膚科専修医
  • 1999 - 2001  東京大学 医学部付属病院皮膚科研修医


  • 1993 - 1999  Jikei University  Faculty of Medicine  School of Medicine

Association Memberships


Published Papers

  • Takeo Maekawa, Mayumi Komine, Satoru Murata, Noriyoshi Fukushima, Mamitaro Ohtsuki
    JOURNAL OF DERMATOLOGY 42 (3) 318 - 321 0385-2407 2015/03 [Refereed][Not invited]
    Intravascular large B-cell lymphoma (IVLBCL) is classified as a rare type of non-Hodgkin's B-cell lymphoma by the World Health Organization. It is characterized by the presence of lymphoma cells in the lumens of the small vessels of several organs, most notably the skin. Diagnosis of IVLBCL is difficult because of the lack of lymphadenopathy and because lesions need to be histologically confirmed via a biopsy of the affected organs. Random skin biopsy (RSB) of normal-appearing skin is a useful and apparently safe means of evaluating IVLBCL. However, patients with IVLBCL often exhibit thrombocytopenia, and we describe a case in which a patient with thrombocytopenia experienced hemorrhagic shock and died shortly after RSB. For this reason, we reviewed cases of RSB performed at our hospital and found that the middle adipose tissue contained a higher percentage of atypical lymphoid cells than other layers of the skin. On the basis of our findings, we propose a strategy for the safer performance of RSB in IVLBCL patients with thrombocytopenia and coagulation abnormalities.
  • Takeo Maekawa, Mayumi Komine, Satoru Murata, Mamitaro Ohtsuki
    JOURNAL OF DERMATOLOGY 41 (10) 944 - 946 0385-2407 2014/10 [Refereed][Not invited]
  • Yukiko Miyamoto, Mayumi Komine, Yuka Takatsuka, Takeo Maekawa, Satoru Murata, Kazue Nakanaga, Norihisa Ishii, Mamitaro Ohtsuki
    JOURNAL OF DERMATOLOGY 41 (8) 771 - 772 0385-2407 2014/08 [Refereed][Not invited]
  • Takeo Maekawa, Mayumi Komine, Satoru Murata, Mamitaro Ohtsuki
    JOURNAL OF DERMATOLOGY 40 (12) 1058 - 1059 0385-2407 2013/12 [Refereed][Not invited]
  • Nobuki Maki, Mayumi Komine, Yuka Takatsuka, Takeo Maekawa, Satoru Murata, Mamitaro Ohtsuki
    Journal of Dermatology 40 (4) 299 - 300 0385-2407 2013/04 [Refereed][Not invited]
  • Makiko Morita, Mayumi Komine, Yuka Takatsuka, Satomi Hosoda, Hiroshi Onda, Takeo Maekawa, Satoru Murata, Mamitaro Ohtsuki
    JOURNAL OF DERMATOLOGY 40 (2) 132 - 134 0385-2407 2013/02 [Refereed][Not invited]
  • Takeo Maekawa, Masatoshi Jinnin, Mamitaro Ohtsuki, Hironobu Ihn
    The Journal of dermatology 2 40 (2) 98 - 101 0385-2407 2013/02 [Refereed][Not invited]
    Systemic sclerosis (SSc) is an autoimmune systemic connective tissue disorder characterized by sclerotic change of the skin and multiple internal organs. Although the pathogenesis of this disorder is still unknown, overproduction of extracellular matrix proteins, including collagens and fibronectin, and aberrant immune activation may be involved in the mechanism. Interleukin (IL)-1 is one of the key regulators of inflammatory response. IL-1 is also involved in regulating connective tissue remodeling and cellular differentiation of epithelial and ectodermal cells. There are three major members of the IL-1 family: IL-1α, IL-1β and IL-1 receptor antagonist. IL-1α was first described as a factor derived from keratinocytes that stimulates thymocyte proliferation. IL-1α plays a crucial role in procollagen production by fibroblasts derived from patients with SSc. The present study was undertaken to investigate the serum levels of IL-1α in patients with SSc. Serum samples were obtained from 66 Japanese patients with SSc and 19 healthy controls. Levels of serum IL-1α were measured with a specific enzyme-linked immunoassay kit. Mean serum levels were significantly higher in SSc patients than in those healthy control subjects. Moreover, contracture of phalanges was found at a significantly lower prevalence in SSc patients with elevated serum IL-1α levels than those with normal levels. These results suggest that IL-1α may play a role in the pathogenesis of SSc.
  • Takeo Maekawa, Masatoshi Jinnin, Hironobu Ihn
    EUROPEAN JOURNAL OF DERMATOLOGY 21 (4) 534 - 538 1167-1122 2011/07 [Refereed][Not invited]
    Dermatofibroma (DF) and dermatofibrosarcoma protuberans (DFSP) are benign or intermediate malignant fibrotic dermal tumors. The contribution of transforming growth factor beta (TGF-beta) in the progression of sclerosis in fibrotic diseases has been implicated. To clarify the involvement of TGF-beta signaling in the pathogenesis of DF or DFSP, we investigated the expression of thrombospondin-1 (TSP-1), which mediates TGF-beta 1 activation, on those fibrotic tumors. In the present study, we examined the expression of TSP-1 in DF and DFSP using immunohistochemical analysis and immunoblotting. In immunohistochemical staining, the expression of TSP-1 was detected weakly on epidermis and epidermal appendages, and hardly in fibroblasts in normal skin sections. The expression levels of TSP-1 were elevated in DFSP cells in comparison to normal dermal sections or DF cells. On the other hand, there was no significant difference in the protein levels in vitro of TSP-1 among normal fibroblasts, DF cells, and DFSP cells. Although the contribution of TGF-beta signaling to DF or DFSP is still unknown, the expression patterns of TSP-1 in DF cells and DFSP cells may be helpful in differential diagnosis of these tumors.
  • Yuri Masui, Mayumi Komine, Takafumi Kadono, Nobuko Ishiura, Takeo Maekawa, Hironobu Ihn, Kanako Kikuchi, Kunihiko Tamaki
    Journal of cutaneous pathology 35 Suppl 1 55 - 8 0303-6987 2008/10 [Refereed][Not invited]
    A 46-year-old man had a cystic mass on the right side of his scalp. Histological examination revealed a cystic dermal nodule composed of relatively circumscribed lobules of proliferating squamous epithelium, with atypical mitoses and dyskeratotic cells of invasive structure, which was diagnosed as proliferating tricholemmal cystic carcinoma (PTCC). Most of the cyst was composed of thick layers of highly proliferating, atypical, dedifferentiated epithelium (dedifferentiated part), which was attached to a highly proliferative but mildly differentiated part. A completely differentiated, tricholemmal cyst (TC)-like part was also attached to the main cyst, which supports the idea of PTCC beginning in a pre-existing TC. The dedifferentiated and mildly differentiated parts exhibited a high frequency of proliferating cell nuclear antigen (PCNA)-positive cells both in the basal and the suprabasal layers, while PCNA staining was almost negative in the TC-like part. Expression of cytokeratin (CK)10 and CK16 suggested disturbed epidermal differentiation in dedifferentiated part, while TC-like part showed well-differentiated trichilemmal epithelium and the mildly differentiated part was in the middle of these two.
  • Yoshihide Asano, Hironobu Ihn, Takeo Maekawa, Takafumi Kadono, Kunihiko Tamaki
    Clinical rheumatology 25 (3) 396 - 8 0770-3198 2006/05 [Refereed][Not invited]
    We describe a 58-year-old Japanese female who developed polyarteritis nodosa (PN). Her skin disease and systemic symptoms were resistant to dapsone (1.5 mg kg(-1) day(-1)), high-dose oral prednisone (1 mg kg(-1) day(-1)) and azathioprine (2 mg kg(-1) day(-1)), and intravenous cyclophosphamide pulse therapy (10 mg kg(-1) day(-1)). She was ultimately treated with infusion of high-dose intravenous immunoglobulin (IVIG) at a dose of 0.1 g kg(-1) daily for five consecutive days weekly for a period of 12 weeks, resulting in remission of his cutaneous and systemic symptoms and successful tapering of his prednisone and azathioprine dose. However, 12 months later, relapsing fever and polyarthritis recurred, and eventually, 24 months later, indurated erythema and punched-out ulcers appeared on the lower legs. These symptoms were reduced after increasing the dose of oral prednisone (1 mg kg(-1) day(-1)). Our case indicates that the high-dose IVIG infusion therapy may be useful for controlling PN in certain periods since the long-term observation revealed deterioration of symptoms. We review related articles and discuss its effectiveness in PN.
  • A Asahina, T Watanabe, A Kishi, N Hattori, A Shirai, S Kagami, R Watanabe, A Le Pavoux, T Maekawa, K Tamaka, K Ohara
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 54 (3) 487 - 493 0190-9622 2006/03 [Refereed][Not invited]
    Background: Treatments of port-wine stains with conventional Pulsed dye laser yield inconsistent results. Objective: We evaluated the efficacy and safety of the longer pulse duration 595-nm dye laser. Methods: Sixty-six adult Japanese patients were enrolled in this prospective Study. The laser treatment with a cooling device was repeated 4 times at 8-week intervals with a consistent setting of 10-ms pulse duration and an energy fluence of 12 J/cm(2) using 7-mm spot size. Results: Improvement of port-wine stains was observed after multiple treatments, and 67% of the patients achieved either good or excellent response after the following treatment. Transient purpura, edema, or both were noted immediately after each treatment (76%-79% and 58%-67%, respectively). Hyperpigmentation (8%-17%) and hypopigmentation (6%-14%) were also mild and their occurrence did not increase by repeating treatments. Limitations: Eighty five percent of the patients were classified as having Fitzpatrick skin type IV. Conclusion: Our study indicated that the 595-nm dye laser with 10-ms pulse duration may be effective and well tolerated in the treatment of port-wine stains in adult Asians.
  • Gojiro Nakagami, Hiromi Sanada, Atsuko Kitagawa, Etsuko Tadaka, Takeo Maekawa, Takashi Nagase, Chizuko Konya
    Dermatology (Basel, Switzerland) 213 (4) 293 - 9 1018-8665 2006 [Refereed][Not invited]
    BACKGROUND: Incontinence leads to a reduced skin barrier function, while also increasing the risk of skin breakdown. AIM: To investigate the perianal skin barrier function of elderly patients with or without incontinence. METHODS: We compared the skin barrier function by investigating the skin hydration, the skin pH, the amount of ceramide and by making a dermatological skin inspection of the perianal region in patients with and without incontinence. RESULTS: Twenty-one incontinent patients (70.0%) showed a glossy skin, which indicates impairment of the skin barrier while none of the patients in the continence group did so. In the incontinence group, those who had a glossy skin showed a significantly greater skin pH and total amount of ceramide than those with a normal skin (p = 0.0099, p = 0.0179, respectively). CONCLUSIONS: These results demonstrate that a glossy skin may be a useful indicator of a reduced perianal skin barrier function.

Books etc

  • 皮膚疾患ベスト治療 臨床決断の戦略・エビデンス
    前川武雄 (Contributor下腿潰瘍)
    秀潤社 2016/02
  • ドレッシング材のすべて 皮膚科医による根拠に基づく選び方・使い方
    前川武雄 (Editor総論、編集)
    秀潤社 2015/09
  • WOC Nursing 2014年12月号 傷あとがキレイに治る! ドレッシング材
    前川武雄 (Supervisor)
    医学出版 2014/12
  • Visual Dermatology 2014年5月号 ドレッシング材の種類と使い方
    前川武雄 (Supervisor)
  • 創傷と痛み
    前川武雄 (Contributor放射線皮膚障害の痛みに対処する)
    金原出版 2013
  • 内科で役立つ一発診断から迫る皮膚疾患の鑑別診断
    前川武雄 (Contributor下肢の有痛性紅斑、硬結)
    羊土社 2013
  • 皮膚科臨床アセット12 新しい創傷治療のすべて
    前川武雄 (Contributor創傷一般)
    中山書店 2013
  • 創傷・熱傷ガイドライン
    前川武雄 (Contributor創傷一般)
    金原出版 2012
  • 最新学校保健安全ハンドブック
    前川武雄 (Contributor児童・生徒のアレルギー)
    教育開発研究所 2009
  • 性感染症アトラス
    前川武雄 (Contributor扁平コンジローマ)
    秀潤社 2008
  • すぐに役立つ日常皮膚診療における私の工夫
    前川武雄 (Contributor稗粒腫)
    全日本病院出版会 2007
  • 手術に役立つリンパ流アトラス
    前川武雄 (Contributor各論3(胸腹部))
    秀潤社 2006


  • 【傷あとがキレイに治る!ドレッシング材 注目の創傷被覆材を用いた難治性皮膚潰瘍・褥瘡の治療】 ドレッシング材による創傷治療のまとめ
    前川武雄  WOC Nursing  2-  (12)  86  -92  2014/12  [Not refereed][Invited]
  • 皮膚科医が行うべき難治性皮膚潰瘍の対処法とは? 創傷・熱傷ガイドラインの改訂版の変更点についても言及 下肢静脈瘤が原因となる下腿潰瘍の予防と治療 血管内レーザーと弾性ストッキングを中心に
    中村 泰大, 伊藤 孝明, 久木野 竜一, 皿山 泰子, 高原 正和, 谷岡 未樹, 前川 武雄, 八代 浩  日本皮膚科学会雑誌  124-  (13)  2912  -2915  2014/12  [Not refereed][Invited]
  • レパヴー・アンドレ, 井上 雄二, 長谷川 稔, 前川 武雄, 新谷 洋一, 藤田 英樹, 辻田 淳  日本皮膚科学会雑誌  124-  (13)  2896  -2899  2014/12  [Not refereed][Invited]
  • 藤田 有理香, 前川 武雄, レパヴー・アンドレ, 村田 哲, 大槻 マミ太郎  Skin Cancer  29-  (2)  181  -188  2014/11  [Refereed][Not invited]
  • 藤田 有理香, 前川 武雄, 小宮根 真弓, 村田 哲, 大槻 マミ太郎, 添野 文雄  Skin Cancer  29-  (2)  176  -180  2014/11  [Refereed][Not invited]
  • (Part2.)ドレッシング材の色々とその基本的な使い方(case 19) ソフトシリコンドレッシング
    藤田有理香, 前川武雄  Visual Dermatology  13-  (5)  554  -555  2014/05  [Not refereed][Invited]
  • (Part2.)ドレッシング材の色々とその基本的な使い方(case 17) ハイドロジェル
    岸晶子, 小川洋子, 前川武雄  Visual Dermatology  13-  (5)  550  -551  2014/05  [Not refereed][Invited]
  • (Part2.)ドレッシング材の色々とその基本的な使い方(case 14) ハイドロファイバー
    足立晃正, 前川武雄  Visual Dermatology  13-  (5)  542  -543  2014/05  [Not refereed][Invited]
  • (Part1.)病態別の使い方(case 07) 段差の大きな創傷
    藤田英樹, 前川武雄  Visual Dermatology  13-  (5)  520  -521  2014/05  [Not refereed][Invited]
  • (Part1.)病態別の使い方(case 02) 滲出液の多い創傷
    前川武雄  Visual Dermatology  13-  (5)  508  -509  2014/05  [Not refereed][Invited]
  • ドレッシング材によるwound bed preparationとmoist wound healing
    前川武雄  Visual Dermatology  13-  (5)  502  -504  2014/04  [Not refereed][Invited]
  • 前川 武雄, アンドレ レパヴー, 長谷川 稔  日本皮膚科学会雑誌 = The Japanese journal of dermatology  123-  (13)  2878  -2881  2013/12  [Not refereed][Not invited]
  • 藤田 有理香, 前川 武雄, 塚原 理恵子  臨床皮膚科  67-  (2)  159  -162  2013/02  [Not refereed][Not invited]
  • MAEKAWA Takeo, FUJITA Yurika, MORITA Makiko, TSUKAHARA Rieko, WAKATABI Kouji, KOMINE Mayumi, MURATA Satoru, OHTSUKI Mamitaro, KAWADA Hirotoshi, YAMAGUCHI Takehiko  Skin Cancer  27-  (3)  355  -360  2013  [Not refereed][Not invited]
    An 87-year-old man noticed a nodule on his abdomen a month ago, which had been increasing in size. Computed tomography (CT) demonstrated a tumor within the subcutaneous adipose tissue which showed iso-density to the muscle, and which was 22 mm in size. When magnetic resonance imaging (MRI) was performed two months later, the tumor showed rapid growth to 34 mm in size, and infiltration to the muscle. Histopathological examination of an incisional biopsy suggested spindle cell sarcoma. Immunohistochemical examination showed the tumor cells were negative for CD34, smooth muscle actin and pan-cytokeratin. Based on these findings, synovial sarcoma was suspected, and we proceeded with molecular diagnostic analysis by FISH (fluorescence in situ hybridization) using a dual-color, break-apart SS18 probe. As a result, translocation involving the SS18 gene was detected by the split signal, and a diagnosis of synovial sarcoma was confirmed.[Skin Cancer (Japan) 2012 ; 27 : 355-360]
  • 井上 雄二, 長谷川 稔, 前川 武雄  日本皮膚科学会雑誌 = The Japanese journal of dermatology  122-  (13)  3620  -3623  2012/12  [Not refereed][Not invited]
  • 藤田 有理香, 前川 武雄, レパヴー アンドレ  皮膚科の臨床  54-  (9)  1263  -1265  2012/09  [Not refereed][Not invited]
  • 藤田 有理香, 前川 武雄, 塚原 理恵子  皮膚科の臨床  54-  (8)  1087  -1091  2012/08  [Not refereed][Not invited]
  • 藤田 有理香, 前川 武雄  臨床皮膚科  66-  (4)  329  -332  2012/04  [Not refereed][Not invited]
  • 吉野 雄一郎, 大塚 幹夫, 川口 雅一, 境 恵祐, 橋本 彰, 林 昌浩, 間所 直樹, 浅野 善英, 安部 正敏, 石井 貴之, 爲政 大幾, 伊藤 孝明, 井上 雄二, 今福 信一, 入澤 亮吉, 大塚 正樹, 小川 文秀, 門野 岳史, 川上 民裕, 久木野 竜一, 幸野 健, 小寺 雅也, 高原 正和, 谷岡 未樹, 中西 健史, 中村 泰大, 長谷川 稔, 藤本 学, 藤原 浩, 前川 武雄, 松尾 光馬, 山崎 修, レパヴー アンドレ, 立花 隆夫, 尹 浩信  日本皮膚科学会雑誌  121-  (14)  3279  -3306  2011/12  [Not refereed][Not invited]
  • 長谷川 稔, 前川 武雄, レパブー アンドレ, 井上 雄二  日本皮膚科学会雑誌  121-  (13)  2872  -2874  2011/12  [Not refereed][Not invited]
  • 前川 武雄  日本皮膚科学会雑誌  121-  (13)  3188  -3191  2011/12  [Not refereed][Not invited]
  • 前川 武雄  日本皮膚科学会雑誌  121-  (13)  3188  -3191  2011/12  [Not refereed][Not invited]
  • 長谷川 稔, 前川 武雄, アンドレ レパブー  日本皮膚科学会雑誌  121-  (13)  2872  -2874  2011/12  [Not refereed][Not invited]
  • 藤本 学, 浅野 善英, 石井 貴之, 小川 文秀, 川上 民裕, 小寺 雅也, 安部 正敏, 爲政 大幾, 伊藤 孝明, 井上 雄二, 今福 信一, 入澤 亮吉, 大塚 正樹, 大塚 幹夫, 門野 岳史, 川口 雅一, 久木野 竜一, 幸野 健, 境 恵祐, 高原 正和, 谷岡 未樹, 中西 健史, 中村 泰大, 橋本 彰, 長谷川 稔, 林 昌浩, 藤原 浩, 前川 武雄, 松尾 光馬, 間所 直樹, 山崎 修, 吉野 雄一郎, レパヴー アンドレ, 立花 隆夫, 尹 浩信  日本皮膚科学会雑誌  121-  (11)  2187  -2223  2011/10  [Not refereed][Not invited]
  • 爲政 大幾, 安部 正敏, 中西 健史, 松尾 光馬, 山崎 修, 浅野 善英, 石井 貴之, 伊藤 孝明, 井上 雄二, 今福 信一, 入澤 亮吉, 大塚 正樹, 大塚 幹夫, 小川 文秀, 門野 岳史, 小寺 雅也, 川上 民裕, 川口 雅一, 久木野 竜一, 幸野 健, 境 恵祐, 高原 正和, 谷岡 未樹, 中村 泰大, 橋本 彰, 長谷川 稔, 林 昌浩, 藤本 学, 藤原 浩, 前川 武雄, 間所 直樹, 吉野 雄一郎, レパヴー アンドレ, 立花 隆夫, 尹 浩信  日本皮膚科学会雑誌  121-  (10)  1997  -2035  2011/09  [Not refereed][Not invited]
  • 立花 隆夫, 今福 信一, 入澤 亮吉, 大塚 正樹, 門野 岳史, 藤原 浩, 浅野 善英, 安部 正敏, 石井 貴之, 爲政 大幾, 伊藤 孝明, 井上 雄二, 大塚 幹夫, 小川 文秀, 小寺 雅也, 川上 民裕, 川口 雅一, 久木野 竜一, 幸野 健, 境 恵祐, 高原 正和, 谷岡 未樹, 中西 健史, 中村 泰大, 橋本 彰, 長谷川 稔, 林 昌浩, 藤本 学, 前川 武雄, 松尾 光馬, 間所 直樹, 山崎 修, 吉野 雄一郎, レパヴー アンドレ, 尹 浩信  日本皮膚科学会雑誌  121-  (9)  1791  -1839  2011/08  [Not refereed][Not invited]
  • 井上 雄二, 長谷川 稔, 前川 武雄  日本皮膚科学会雑誌  121-  (8)  1539  -1559  2011/08  [Not refereed][Not invited]
  • YAGISHITA Yurika, MAEKAWA Takeo  Skin Cancer  25-  (3)  367  -371  2011/02  [Not refereed][Not invited]
    A 76-year-old Japanese woman presented with an erythematous lesion on the vulva which had been noticed about 2 years earlier and grown rapidly during the last 6 months. Physical examination revealed a nodule accompanied by erythematous plaque from the left large pudendal lip to the anus, and some swollen bilateral inguinal lymph nodes. Biopsy confirmed the diagnosis of subcutaneous invasion of extramammary Paget's disease. Computed tomography showed metastasis of bilateral inguinal and para-aortic lymph nodes. She was treated with local excision of the primary lesion, followed by weekly docetaxel and trastuzumab, as immunohistochemical examination revealed strongly HER2 positive. After 7 courses, lymph node metastasis disappeared with few adverse effects. Eight weeks after chemotherapy, the complete response had continued. The weekly docetaxel-trastuzumab combination chemotherapy can be a very effective and well-tolerated therapy for patients with HER-2-positive advanced extramammary Paget's disease.[Skin Cancer (Japan) 2010 ; 25 : 367-371]
  • 前川 武雄  インテンシヴィスト  3-  (3)  549  -551  2011  [Not refereed][Not invited]
  • 長谷川 稔, 井上 雄二, 前川 武雄, レパブー アンドレ  日本皮膚科学会雑誌  120-  (13)  2873  -2875  2010/12  [Not refereed][Not invited]
  • 藤田 有理香, Le Pavoux, Andres J, 前川 武雄  臨床皮膚科  63-  (4)  297  -300  2009/04  [Not refereed][Not invited]
  • NAGAO Mayuko, KADONO Takafumi, KOMINE Mayumi, KIKUCHI Kanako, TAMAKI Kunihiko, MAEKAWA Takeo, SIKADA Junichiro, IHN Hironobu  Japanese journal of dermatology  118-  (6)  1079  -1083  2008/05  [Not refereed][Not invited]
  • 増井 友里, 前川 武雄, 山根 謙一, 門野 岳史, 尹 浩信, 朝比奈 昭彦, 菊池 かな子, 玉置 邦彦  皮膚科の臨床  48-  (11)  1595  -1600  2006/10  [Not refereed][Not invited]
    71歳男。患者は2〜3年前から陰茎亀頭部にそう痒を伴う紅斑を自覚した。皮疹は徐々に拡大、糜爛化し、疼痛を伴うようになった。その後、皮膚生検で有棘細胞癌と診断され、手術目的で入院となった。病理組織学的所見では表皮は一部欠損し、好酸性の腫瘍塊が真皮内へ索状に進展していた。一部では腫瘍塊は真皮深層から陰茎海綿体直上まで島状に浸潤していた。個々の細胞は大小不同で異型性が強く、個細胞角化や分裂像も散見できた。以上より有棘細胞癌、T1N0MO、stage Iと診断し、尿道口近傍であったため、陰茎部分切除術を施行した。化学療法等は追加しなかったが、術後2年経過現在、再発および転移は認めず、排尿障害も認められていない。
  • 増井 友里, 前川 武雄, 山根 謙一  皮膚科の臨床  48-  (11)  1601  -1604  2006/10  [Not refereed][Not invited]
  • 嶋津 苗胤, 前川 武雄, 門野 岳史  皮膚科の臨床  48-  (5)  679  -682  2006/05  [Not refereed][Not invited]
  • MAEKAWA Takeo, OHARA Kuniaki  日本皮膚科学会雑誌 = THE JAPANESE JOURNAL OF DERMATOLOGY  114-  (7)  1283  -1286  2004/06  [Not refereed][Not invited]
  • Maekawa Takeo, Jinnin Masatoshi, Ihn Hironobu, Tamaki Kunihiko  Connective tissue  36-  (2)  103  -103  2004  [Not refereed][Not invited]
  • MAEKAWA Takeo, WAKUGAWA Motoshi, SUGAYA Makoto, HAYASHI Nobukazu, ASAHINA Akihiko, OKOCHI Hitoshi, IZUTSU Kouji, HIRAI Hisamaru, TAKEUCHI Kengo, TAMAKI Kunihiko  日本皮膚科学会雑誌  112-  (6)  829  -836  2002/05  [Not refereed][Not invited]

Copyright © MEDIA FUSION Co.,Ltd. All rights reserved.