takahashi masafumi

FacultyDivisionofInflammationResearch
Job titleProfessorWeb site

Profile

Research Keywords

    Cardiology

Research Areas

  • Clinical internal medicine / Circulatory organs internal medicine

Career

  • 2009
    -
    Today
    Jichi Medical University, Professor
  • 1997
    -
    2001
    Instructor, Cardiology, Jichi Medical School

Academic Background

  • -
    1997
    Graduate School, Division of Medicine, Jichi Medical University (japan)
  • -
    1989
    Faculty of Medicine, Jichi Medical University (japan)

Research Activities

Papers(paper)

  • Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease.
    Nakamura J, Watanabe S, Kimura H, Kobayashi M, Karasawa T, Kamata R, Usui-Kawanishi F, Sadatomo A, Mizukami H, Nagi-Miura N, Ohno N, Kasahara T, Minota S, Takahashi M
    Scientific reports 8(1) 7601 May 2018
  • Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
    Karasawa T, Kawashima A, Usui-Kawanishi F, Watanabe S, Kimura H, Kamata R, Shirasuna K, Koyama Y, Sato-Tomita A, Matsuzaka T, Tomoda H, Park SY, Shibayama N, Shimano H, Kasahara T, Takahashi M
    Arteriosclerosis, thrombosis, and vascular biology 38(4) 744-756 Apr. 2018
  • ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages.
    Kawashima A, Karasawa T, Tago K, Kimura H, Kamata R, Usui-Kawanishi F, Watanabe S, Ohta S, Funakoshi-Tago M, Yanagisawa K, Kasahara T, Suzuki K, Takahashi M
    Journal of immunology (Baltimore, Md. : 1950) 199(10) 3614-3622 Nov. 2017
  • Interaction of Neutrophils with Macrophages Promotes IL-1β Maturation and Contributes to Hepatic Ischemia-Reperfusion Injury.
    Sadatomo A, Inoue Y, Ito H, Karasawa T, Kimura H, Watanabe S, Mizushina Y, Nakamura J, Kamata R, Kasahara T, Horie H, Sata N, Takahashi M
    Journal of immunology (Baltimore, Md. : 1950) 199(9) 3306-3315 Nov. 2017
  • The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
    Kobayashi M, Usui-Kawanishi F, Karasawa T, Kimura H, Watanabe S, Mise N, Kayama F, Kasahara T, Hasebe N, Takahashi M
    PloS one 12(5) e0176676 2017
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Papers(paper)close
  • Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease.
    Nakamura J, Watanabe S, Kimura H, Kobayashi M, Karasawa T, Kamata R, Usui-Kawanishi F, Sadatomo A, Mizukami H, Nagi-Miura N, Ohno N, Kasahara T, Minota S, Takahashi M
    Scientific reports 8(1) 7601 May 2018
  • Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
    Karasawa T, Kawashima A, Usui-Kawanishi F, Watanabe S, Kimura H, Kamata R, Shirasuna K, Koyama Y, Sato-Tomita A, Matsuzaka T, Tomoda H, Park SY, Shibayama N, Shimano H, Kasahara T, Takahashi M
    Arteriosclerosis, thrombosis, and vascular biology 38(4) 744-756 Apr. 2018
  • ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages.
    Kawashima A, Karasawa T, Tago K, Kimura H, Kamata R, Usui-Kawanishi F, Watanabe S, Ohta S, Funakoshi-Tago M, Yanagisawa K, Kasahara T, Suzuki K, Takahashi M
    Journal of immunology (Baltimore, Md. : 1950) 199(10) 3614-3622 Nov. 2017
  • Interaction of Neutrophils with Macrophages Promotes IL-1β Maturation and Contributes to Hepatic Ischemia-Reperfusion Injury.
    Sadatomo A, Inoue Y, Ito H, Karasawa T, Kimura H, Watanabe S, Mizushina Y, Nakamura J, Kamata R, Kasahara T, Horie H, Sata N, Takahashi M
    Journal of immunology (Baltimore, Md. : 1950) 199(9) 3306-3315 Nov. 2017
  • The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
    Kobayashi M, Usui-Kawanishi F, Karasawa T, Kimura H, Watanabe S, Mise N, Kayama F, Kasahara T, Hasebe N, Takahashi M
    PloS one 12(5) e0176676 2017

Outside Fund Adoption

  • Study on Mechanism of Atherogenesis
  • Regenerative Therapy for Cardiovasuclar Diseases
    :Grant-in-Aid for Scientific Research
    Project Year :2001 - 2006
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Outside Fund Adoptionclose
  • Study on Mechanism of Atherogenesis
  • Regenerative Therapy for Cardiovasuclar Diseases
    :Grant-in-Aid for Scientific Research
    Project Year :2001 - 2006


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