Researchers Database

ichihashi ko

    ComprehensiveMedicine1 Professor
Last Updated :2021/10/17

Researcher Information

Degree

  • Doctor of Medical Science(Jichi Medical University)

J-Global ID

Research Interests

  • 胎児・新生児医学   小児科学   Embryology and Newborn Medicine   Pediatrics   

Research Areas

  • Life sciences / Fetal medicine/Pediatrics
  • Life sciences / Fetal medicine/Pediatrics

Academic & Professional Experience

  • 2008/01 - Today  Saitama Medical Center Jichi Meducal Universityprofessor
  • 2006/04 - 2007/12  Jichi Children's Medical Center Tochigiassociated professor
  • 1997/12 - 2006/03  - 自治医科大学 講師
  • 1996 - 1997  Jichi Medical University
  • 1996 - 1997  Jichi Medical School, Assistant
  • 1997  - Jichi Medical School, Assistant Professor
  • 1994 - 1996  アレキサンダー・フォン・フニボルト財団 研究員
  • 1994 - 1996  Research Fellow of Alexandor von Humbolt
  • 1989 - 1994  Jichi Medical University
  • 1989 - 1994  Jichi Medical School, Assistant
  • Foundation
  • Jichi Medical UniversityProfessor

Education

  •        - 1984  Tokyo Medical University  医学部  医学
  •        - 1984  Tokyo Medical University  Faculty of Medicine

Association Memberships

  • 日本脳神経超音波研究会   日本小児神経学会   日本小児循環器学会   日本心臓病学会   日本新生児学会   日本超音波医学会   日本小児科学会   

Books etc

  • 胃洗浄
    ()
    三共株式会社 2003
  • リウマチ熱の治療薬
    ()
    メディカルレビュー社 2002
  • Drugs againist rheumatic fever
    ()
    Medical Review Co. 2002
  • -こどものおもな病気- 家庭の医学
    ()
    時事通信社 2001
  • -Main diseases of children- Medical encyclopedia for home use
    ()
    Jijitsusin Co. 2001
  • 新生児・乳児の疾患
    ()
    新超音波医学 2000
  • 胃洗浄
    ()
    今日の小児治療指針 2000
  • Disease in neonates and infants
    ()
    Current Textbook of Ultrasonics in Medicine 2000
  • Gastric lavage
    ()
    Today's Therapy in Pediatrics 2000

MISC

  • Neurosonology  16-  (1)  22  -27  2003  [Not refereed][Not invited]
  • 小児の発熱
    JIM  13-  764  -767  2003  [Not refereed][Not invited]
  • Ko ICHIHASHI, Sadayuki YANO, Mariko MOMOI  Neurosonology  16-  (1)  22  -27  2003  [Not refereed][Not invited]
  • K Ichihashi, M Iino, Y Eguchi, A Uchida, Y Honma, M Momoi  EARLY HUMAN DEVELOPMENT  69-  (1-2)  35  -46  2002/10  [Not refereed][Not invited]
     
    The objective of this study is to determine the difference of the flow velocities of left and right cerebral arteries. We also studied the effect of head position to the cerebral arterial flow velocities. Eligible for inclusion in this study were 60 neonatal infants whose gestational age was 33.1 +/- 3.5 weeks and whose birth weight was 1793 613 g. The ultrasonographic examinations were performed in the first and second weeks after birth. In an axial scan through a temporal window, the Doppler sample volume was positioned at the center of the M1 portion of the middle cerebral artery and the flow velocity curve was detected. No statistical difference was seen in the flow velocities between the left and right middle cerebral arteries. However, the flow velocities in the upper side were significantly higher than those in the lower side. RI in the upper side was significantly smaller than that in the lower one. This change of flow velocities stabilized in 5 min after the head was turned upside down. The effect of head positioning to the intracranial blood flow must be considered when cerebral ultrasonography of neonates is performed. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
  • K Ichihashi, M Iino, Y Eguchi, A Uchida, Y Honma, M Momoi  EARLY HUMAN DEVELOPMENT  69-  (1-2)  35  -46  2002/10  [Not refereed][Not invited]
     
    The objective of this study is to determine the difference of the flow velocities of left and right cerebral arteries. We also studied the effect of head position to the cerebral arterial flow velocities. Eligible for inclusion in this study were 60 neonatal infants whose gestational age was 33.1 +/- 3.5 weeks and whose birth weight was 1793 613 g. The ultrasonographic examinations were performed in the first and second weeks after birth. In an axial scan through a temporal window, the Doppler sample volume was positioned at the center of the M1 portion of the middle cerebral artery and the flow velocity curve was detected. No statistical difference was seen in the flow velocities between the left and right middle cerebral arteries. However, the flow velocities in the upper side were significantly higher than those in the lower side. RI in the upper side was significantly smaller than that in the lower one. This change of flow velocities stabilized in 5 min after the head was turned upside down. The effect of head positioning to the intracranial blood flow must be considered when cerebral ultrasonography of neonates is performed. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
  • K Ichihashi, M Iino, Y Eguchi, A Uchida, Y Honma, M Momoi  EARLY HUMAN DEVELOPMENT  68-  (1)  55  -64  2002/06  [Not refereed][Not invited]
     
    The objective of this study is to determine the causes of asymmetry of the lateral ventricles in neonates. We also studied the effect of head position and the relationship of body weight at birth in regard to lateral ventricular size. Eligible for inclusion in this study were 60 neonatal infants whose gestational age was 33.1+/-3.5 weeks and whose birth weight was 1793 613 g. Ultrasonographic examinations were performed at the first and the second weeks after birth. In parasagittal and coronal scans through the posterior horn of the lateral ventricle, the lateral ventricle was traced and its area was measured. We found no significant variation of ventricular size in relation to body weight at birth. The left ventricular size was larger than the right one. The difference of the left and right ventricular sizes was partially effected by head position. The ratio of left to right lateral ventricular sizes showed a very wide distribution. We considered that ventricular asymmetry is not pathological, but due to individual differences. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
  • K Ichihashi, M Iino, Y Eguchi, A Uchida, Y Honma, M Momoi  EARLY HUMAN DEVELOPMENT  68-  (1)  55  -64  2002/06  [Not refereed][Not invited]
     
    The objective of this study is to determine the causes of asymmetry of the lateral ventricles in neonates. We also studied the effect of head position and the relationship of body weight at birth in regard to lateral ventricular size. Eligible for inclusion in this study were 60 neonatal infants whose gestational age was 33.1+/-3.5 weeks and whose birth weight was 1793 613 g. Ultrasonographic examinations were performed at the first and the second weeks after birth. In parasagittal and coronal scans through the posterior horn of the lateral ventricle, the lateral ventricle was traced and its area was measured. We found no significant variation of ventricular size in relation to body weight at birth. The left ventricular size was larger than the right one. The difference of the left and right ventricular sizes was partially effected by head position. The ratio of left to right lateral ventricular sizes showed a very wide distribution. We considered that ventricular asymmetry is not pathological, but due to individual differences. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
  • こどもがよくカゼをひくのは病気か?
    JOHNS  18-  657  -658  2002  [Not refereed][Not invited]
  • Does a child has a cold many times?
    JOHNS  18-  657  -658  2002  [Not refereed][Not invited]
  • K Ichihashi, F Berger, PE Lange  PEDIATRIC CARDIOLOGY  22-  (6)  503  -508  2001/11  [Not refereed][Not invited]
     
    To compare the flow pattern of the superior caval vein (superior vena cava; SVC) after catheter therapy with that after open-heart surgery, we examined the flow velocity curves of the SVC in 10 pediatric patients who underwent catheter closure of artial septal defect (ASD) and in 20 pediatric patients who underwent open-heart surgery. We used pulsed Doppler examinations to record the velocity curves. On the velocity curve of the SVC in children after open-heart surgery, the velocity in systole was lower than that in diastole, which is contrary to the normal pattern. The velocity in systole increased more than that in diastole during inspiration, which also differs from the normal pattern. In contrast, the velocity curve of the SVC in patients after catheter therapy showed a normal pattern. The change of flow velocity during respiration became smaller after treatment in the surgery group, although it did not change after treatment in the catheter group. These results might indicate less reserve ability in the right atrium in patients who undergo open-heart surgery. ASD closure by catheter is useful not only for its economy and noninvasiveness but also for its potential to contribute conservation of right atrial function.
  • K Ichihashi, F Berger, PE Lange  PEDIATRIC CARDIOLOGY  22-  (6)  503  -508  2001/11  [Not refereed][Not invited]
     
    To compare the flow pattern of the superior caval vein (superior vena cava; SVC) after catheter therapy with that after open-heart surgery, we examined the flow velocity curves of the SVC in 10 pediatric patients who underwent catheter closure of artial septal defect (ASD) and in 20 pediatric patients who underwent open-heart surgery. We used pulsed Doppler examinations to record the velocity curves. On the velocity curve of the SVC in children after open-heart surgery, the velocity in systole was lower than that in diastole, which is contrary to the normal pattern. The velocity in systole increased more than that in diastole during inspiration, which also differs from the normal pattern. In contrast, the velocity curve of the SVC in patients after catheter therapy showed a normal pattern. The change of flow velocity during respiration became smaller after treatment in the surgery group, although it did not change after treatment in the catheter group. These results might indicate less reserve ability in the right atrium in patients who undergo open-heart surgery. ASD closure by catheter is useful not only for its economy and noninvasiveness but also for its potential to contribute conservation of right atrial function.
  • ウイルス感染と合併症
    日本小児循環器学会雑誌  17, 450-451-  2001  [Not refereed][Not invited]
  • 小児の超音波検査-新生児脳疾患-
    日本医師会雑誌  126-  345  -349  2001  [Not refereed][Not invited]
  • Vial infection and cardiac complication
    Journal of Japanese Pediatric Cardiology  450-451-  2001  [Not refereed][Not invited]
  • Ultrasonography of children -brain disease of neonate-
    Journal of Japan Medical Association  126-  345  -349  2001  [Not refereed][Not invited]
  • K Ichihashi, H Shiraishi, M Momoi  CARDIOLOGY IN THE YOUNG  10-  (4)  388  -395  2000/07  [Not refereed][Not invited]
     
    To investigate the pattern of flow in the superior caval vein in children after open heart surgery, we examined the flow velocity curves in 37 patients who had undergone surgical correction of either ventricular or atrial septal defects. The control group consisted of 64 age-matched children. We used pulsed Doppler examinations to record the velocity curves. We measured the highest and lowest peak flow velocities during systole and diastole, and calculated ratios for the various measurements. We found that the velocity of the wave in systole is lower than that of the wave in diastole in the postoperative patients, which is contrary to the normal pattern. The velocity in systole increases more than that in diastole during inspiration, which is also different from the normal pattern. The change in pattern of flow velocity curve during respiration was smaller in patients after surgery than in normal subjects, which might indicate that there is less reserve ability in the right atrium in postoperative patients.
  • 不整脈
    小児科臨床  53-  2173  -2178  2000  [Not refereed][Not invited]
  • 膿胸、気胸
    小児科臨床  53-  2161  -2165  2000  [Not refereed][Not invited]
  • エコー法-頭部-
    37-  80  -83  2000  [Not refereed][Not invited]
  • 頭部の超音波検査法
    小児科診療  63-  2  -6  2000  [Not refereed][Not invited]
  • 子どもの誤飲治療のポイント
    薬の知識  51-  42  -44  2000  [Not refereed][Not invited]
  • 神経超音波医学  13-  20  -26  2000  [Not refereed][Not invited]
  • Arrhythmia
    Japanese J Pediatr  53-  2173  -2178  2000  [Not refereed][Not invited]
  • Pyothorax, Pneumothorax
    Japanese J Pediatr  53-  2161  -2165  2000  [Not refereed][Not invited]
  • Cranial Ultrasonography
    Medicina  37-  80  -83  2000  [Not refereed][Not invited]
  • Cranial ultrasonography
    J Pediatric Practice  63-  2  -6  2000  [Not refereed][Not invited]
  • Therapy of poisoning in children
    Knowledge of drugs  51-  42  -44  2000  [Not refereed][Not invited]
  • Echoencephalography of fetus and newborns
    Neurosonology  13-  20  -26  2000  [Not refereed][Not invited]
  • K. Ichihashi  Journal of Cardiology  35-  (1)  19  -26  2000  [Not refereed][Not invited]
     
    The relationships between age, aortic diameter, and aortic distensibility were examined in patients with Marfan's syndrome. Aortic diameters were measured at the sinus of Valsalva, the ascending aorta, the aortic arch, and the abdominal aorta in 20 patients (aged 5-63 years) with Marfan's syndrome and 30 age-matched normal control subjects. The aortic distensibility was calculated as follows: aortic distensibility = 2 (change in aortic diameter)/(diastolic aortic diameter) (systolic pressure - diastolic pressure). Aortic diameter increased with age in both groups. The diameters of the sinus of Valsalva and the ascending aorta were greater in the Marfan group than in the control group, and increased even after adolescence in patients with Marfan's syndrome. Aortic distensibility was the highest at the abdominal aorta and the lowest at the sinus of Valsalva in both groups. Aortic distensibility decreased with age in both groups, but aortas were less distensible in the Marfan group than in the control group at all ages. The sinus of Valsalva and the ascending aorta dilate abnormally after adolescence in patients with Marfan's syndrome. However, aortic elastic properties in patients with Marfan's syndrome were abnormal even in childhood.
  • 小児における心臓超音検査-今後の展望-
    小児科診療  62-  692  -695  1999  [Not refereed][Not invited]
  • 新しい薬 : カルペリチド
    小児科診療  62-  224  -225  1999  [Not refereed][Not invited]
  • Pediatric echocardiography-view in the fufure-
    The Jounal of Pediatric Practice  62-  692  -695  1999  [Not refereed][Not invited]
  • New drugs : Carperitide
    The Journal of Pediatric Practice  62-  224  -225  1999  [Not refereed][Not invited]
  • Kou ICHIHASHI, Sadayuki YANO, Mariko MOMOI  Neurosonalogy  12-  (1)  23  -27  1999  [Not refereed][Not invited]
  • Pediatrics International  41-  (1)  8  -12  1999  [Not refereed][Not invited]
  • Kou ICHIHASHI, Sadayuki YANO, Mariko MOMOI  Neurosonology  12-  (1)  23  -27  1999  [Not refereed][Not invited]
  • 胸部-新生児の超音波-
    小児科  39-  (6)  573  1998  [Not refereed][Not invited]
  • Kou ICHIHASHI, Sadayuki YANO, Mariko MOMOI  Neurosonology  11-  (4)  166  -169  1998  [Not refereed][Not invited]
  • Ultrasonography of Chest in infants
    Pediatrics of Japan  39-  (6)  573  1998  [Not refereed][Not invited]
  • 臨床検査  41-  (11)  1434  1997  [Not refereed][Not invited]
  • Echoencephalography of children
    Journal of Medical Technology  41-  (11)  1434  1997  [Not refereed][Not invited]
  • K Ichihashi, P Ewert, G Welmitz, PE Lange  HEART AND VESSELS  12-  (5)  216  -220  1997  [Not refereed][Not invited]
     
    In this study we used Doppler echocardiography to examine changes in ventricular diastolic function in neonates. Echocardiograms were performed in 25 healthy neonates at 1-6 days (2.7 +/- 1.6 days) and at 25-35 days (29.4 +/- 3.3 days) after birth. Ventricular inflow velocity curves were recorded using the pulsed-Doppler method. Peak velocities (peak E, A), mean velocities (mean E, A), times (time E, A), and diastolic velocity-time integrals (area E, A) were measured during both early ventricular filling and atrial systole. The acceleration time of the wave during early ventricular filling was also measured. Peak E and A and mean E and A in both ventricles increased at I month after birth. Acceleration times in both ventricles were shortened, The ratio of area E to A in both ventricles and of peak E to A in the left ventricle did not change at 1 month after birth. Only the ratio of peak E to A in the right ventricle increased. The ratio of peak E to (area E + area A), which is thought to be a load-independent index, increased in both ventricles. The authors concluded that ventricular relaxation appears to increase in both ventricles, 1 month after birth, and that changes in diastolic function occur even in neonates.
  • 新生児・未熟児の上大静脈血流パターンの検討
    日本新生児学会雑誌  31-  (1)  179  1995  [Not refereed][Not invited]
  • Analysis of Superior Vena Cava Flow in Term and Preterm Infants
    Journal of Japanese Neonatology  31-  (1)  179  1995  [Not refereed][Not invited]
  • 先天性心疾患が脳血流パターンに及ぼす影響
    神経超音波医学  6-  (1)  9  1993  [Not refereed][Not invited]
  • 新生児・未熟児の心室流入血流,肺静脈血流の検討
    日本小児循環器学会雑誌  8-  (4)  509  1993  [Not refereed][Not invited]
  • Influence of Congenital Heart Disease on Cerebral Blood Flow
    Newrosonology  6-  (1)  9  1993  [Not refereed][Not invited]
  • Transmitral, Transtricuspid and Pulmonary Venous Flow Patterns in Term and Preterm Infauts
    Journal of Japanese Pediatric Cardiology  8-  (4)  509  1993  [Not refereed][Not invited]
  • 肥大型心筋症の心理分析
    日本小児循環器学会雑誌  6-  (4)  1991  [Not refereed][Not invited]
  • Study on psychological states of patients with hypertrophic cardiomyopathy.
    Acta Cardiologica Paediatrica Japonica  6-  (4)  1991  [Not refereed][Not invited]
  • 先天性心疾患児における脳室径および脳血龍パターン〔PI〕の変化
    脳神経超音波  3-  (3)  1990  [Not refereed][Not invited]
  • Pulsatility index and ventricular size of infants with congenital cardiac disease.
    Neurosonology  3-  (3)  1990  [Not refereed][Not invited]
  • Serial imaging of Menkes disease.
    Neuroradiology  32-  (1)  1990  [Not refereed][Not invited]
  • Cerebral and abdominal arterial hemodynamics in preterm infants with patent ductus arteriosus.
    Acta paediatrica Japonica  32-  (4)  1990  [Not refereed][Not invited]
  • 心室中隔欠損における拡張期左右短絡血流の検討
    日本小児循環器学会雑誌  5-  (2)  1989  [Not refereed][Not invited]
  • Diastolic left-to-light shunt flow in ventricular septal defect.
    Acta Cardiologica Paediatrica Japonica  5-  (2)  1989  [Not refereed][Not invited]
  • 未熟児および成熟新生児における心エコー・ドプラ法によるQp、QsおよびQp/Qsの評価
    日本新生児学会雑誌  24-  (4)  1988  [Not refereed][Not invited]
  • Measurement of systemic and pulmonary blood flow using Doppler echocardiography in preterm and mature infants.
    Acta Neonatologica Japonica  24-  (4)  1988  [Not refereed][Not invited]
  • 市橋光, 谷野定之, 倉松俊弘, 宮尾益知, 柳沢正義, 鴨下重彦  脳と発達  19-  (5)  379  -386  1987  [Not refereed][Not invited]
  • Brain ultrasonographic in complication of bacterial meningitis.
    No to Hattatsu  19-  (5)  1987  [Not refereed][Not invited]
  • 呼吸による上大静脈血流の変化の検討
    日本小児循環器学会雑誌  11-  (2)  108  [Not refereed][Not invited]
  • Analysis of Superior Vena Cava Flow Changes by Respiration
    Journal of Japanese Pediatric Cardiology  11-  (2)  108  [Not refereed][Not invited]

Research Grants & Projects

  • 心拍変動解析を用いた新生児の自律神経機能の解析
    Date (from‐to) : 2008 -2012
  • 超音波検査による小児の心機能評価
    Date (from‐to) : 2008 -2012
  • 新生児・乳児の脳エコー法による組織診断
  • 超音波検査を用いた小児の血管弾性率の評価
  • 超音波検査による小児心拡張の新しい指標
  • Tissue Characterization in infants by Ultrasongraphy
  • Assessment of Aortic Elasticity of Children by Ultrasonography
  • A New Index for Diastolic Function of Children by Echocardiography


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