imai yasushi

FacultyDivisionofClinicalPharmacology,DepartmentofPharmacology
Job titleProfessorWeb site

Profile

Research Areas

  • Clinical internal medicine / Cardiovascular medicine

Research Activities

Papers(paper)

  • Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling.
    Tobita T, Nomura S, Fujita T, Morita H, Asano Y, Onoue K, Ito M, Imai Y, Suzuki A, Ko T, Satoh M, Fujita K, Naito AT, Furutani Y, Toko H, Harada M, Amiya E, Hatano M, Takimoto E, Shiga T, Nakanishi T, Sakata Y, Ono M, Saito Y, Takashima S, Hagiwara N, Aburatani H, Komuro I
    Scientific reports 8(1) 1998 Jan. 2018
  • Recurrent Early Coronary Stent Thrombosis under Chronic Disseminated Intravascular Coagulation.
    Oba Y, Hoshide S, Mitama T, Shinohara H, Komori T, Kabutoya T, Imai Y, Ogata N, Kario K
    International heart journal 58(6) 988-992 Dec. 2017
  • Diagnostic accuracy of a new algorithm to detect atrial fibrillation in a home blood pressure monitor.
    Kabutoya T, Imai Y, Hoshide S, Kario K
    Journal of clinical hypertension (Greenwich, Conn.) 19(11) 1143-1147 Nov. 2017
  • Imatinib dramatically alleviates pulmonary tumour thrombotic microangiopathy induced by gastric cancer.
    Kubota K, Shinozaki T, Imai Y, Kario K
    BMJ case reports 2017 Sep. 2017
  • Congenital Corrected Transposition of Great Arteries (TGA).
    Imai Y
    International heart journal 58(1) 5 Feb. 2017
  • Periodontitis May Deteriorate Sinus of Valsalva Dilatation in Marfan Syndrome Patients.
    Suzuki J, Imai Y, Aoki M, Fujita D, Takeda N, Aoyama N, Wakayama K, Ikeda Y, Kumagai H, Akazawa H, Izumi Y, Isobe M, Komuro I, Hirata Y
    International heart journal 57(4) 456-460 Jul. 2016
  • A Case of Useful Short-Spaced Bipolar Pacing of a Left Ventricular Lead to Avoid Phrenic Nerve Stimulation.
    Kabutoya T, Imai Y, Watanabe H, Watanabe T, Komori T, Kario K
    International heart journal 57(1) 118-120 2016
  • A novel mutation of TGFBR2 causing Loeys-Dietz syndrome complicated with pregnancy-related fatal cervical arterial dissections.
    Fujita D, Takeda N, Morita H, Kato M, Nishimura H, Inuzuka R, Taniguchi Y, Nawata K, Hyodo H, Imai Y, Hirata Y, Komuro I
    International journal of cardiology 201 288-290 Dec. 2015
  • Congenital contractural arachnodactyly complicated with aortic dilatation and dissection: Case report and review of literature.
    Takeda N, Morita H, Fujita D, Inuzuka R, Taniguchi Y, Imai Y, Hirata Y, Komuro I
    American journal of medical genetics. Part A 167A(10) 2382-2387 Oct. 2015
  • High incidence and severity of periodontitis in patients with Marfan syndrome in Japan.
    Suzuki J, Imai Y, Aoki M, Fujita D, Aoyama N, Tada Y, Akazawa H, Izumi Y, Isobe M, Komuro I, Nagai R, Hirata Y
    Heart and vessels 30(5) 692-695 Sep. 2015
Display all
Papers(paper)close
  • Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling.
    Tobita T, Nomura S, Fujita T, Morita H, Asano Y, Onoue K, Ito M, Imai Y, Suzuki A, Ko T, Satoh M, Fujita K, Naito AT, Furutani Y, Toko H, Harada M, Amiya E, Hatano M, Takimoto E, Shiga T, Nakanishi T, Sakata Y, Ono M, Saito Y, Takashima S, Hagiwara N, Aburatani H, Komuro I
    Scientific reports 8(1) 1998 Jan. 2018
  • Recurrent Early Coronary Stent Thrombosis under Chronic Disseminated Intravascular Coagulation.
    Oba Y, Hoshide S, Mitama T, Shinohara H, Komori T, Kabutoya T, Imai Y, Ogata N, Kario K
    International heart journal 58(6) 988-992 Dec. 2017
  • Diagnostic accuracy of a new algorithm to detect atrial fibrillation in a home blood pressure monitor.
    Kabutoya T, Imai Y, Hoshide S, Kario K
    Journal of clinical hypertension (Greenwich, Conn.) 19(11) 1143-1147 Nov. 2017
  • Imatinib dramatically alleviates pulmonary tumour thrombotic microangiopathy induced by gastric cancer.
    Kubota K, Shinozaki T, Imai Y, Kario K
    BMJ case reports 2017 Sep. 2017
  • Congenital Corrected Transposition of Great Arteries (TGA).
    Imai Y
    International heart journal 58(1) 5 Feb. 2017
  • Periodontitis May Deteriorate Sinus of Valsalva Dilatation in Marfan Syndrome Patients.
    Suzuki J, Imai Y, Aoki M, Fujita D, Takeda N, Aoyama N, Wakayama K, Ikeda Y, Kumagai H, Akazawa H, Izumi Y, Isobe M, Komuro I, Hirata Y
    International heart journal 57(4) 456-460 Jul. 2016
  • A Case of Useful Short-Spaced Bipolar Pacing of a Left Ventricular Lead to Avoid Phrenic Nerve Stimulation.
    Kabutoya T, Imai Y, Watanabe H, Watanabe T, Komori T, Kario K
    International heart journal 57(1) 118-120 2016
  • A novel mutation of TGFBR2 causing Loeys-Dietz syndrome complicated with pregnancy-related fatal cervical arterial dissections.
    Fujita D, Takeda N, Morita H, Kato M, Nishimura H, Inuzuka R, Taniguchi Y, Nawata K, Hyodo H, Imai Y, Hirata Y, Komuro I
    International journal of cardiology 201 288-290 Dec. 2015
  • Congenital contractural arachnodactyly complicated with aortic dilatation and dissection: Case report and review of literature.
    Takeda N, Morita H, Fujita D, Inuzuka R, Taniguchi Y, Imai Y, Hirata Y, Komuro I
    American journal of medical genetics. Part A 167A(10) 2382-2387 Oct. 2015
  • High incidence and severity of periodontitis in patients with Marfan syndrome in Japan.
    Suzuki J, Imai Y, Aoki M, Fujita D, Aoyama N, Tada Y, Akazawa H, Izumi Y, Isobe M, Komuro I, Nagai R, Hirata Y
    Heart and vessels 30(5) 692-695 Sep. 2015
  • A deletion mutation in myosin heavy chain 11 causing familial thoracic aortic dissection in two Japanese pedigrees.
    Imai Y, Morita H, Takeda N, Miya F, Hyodo H, Fujita D, Tajima T, Tsunoda T, Nagai R, Kubo M, Komuro I
    International journal of cardiology 195 290-292 Sep. 2015
  • A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
    Hirokawa M, Morita H, Tajima T, Takahashi A, Ashikawa K, Miya F, Shigemizu D, Ozaki K, Sakata Y, Nakatani D, Suna S, Imai Y, Tanaka T, Tsunoda T, Matsuda K, Kadowaki T, Nakamura Y, Nagai R, Komuro I, Kubo M
    European journal of human genetics : EJHG 23(3) 374-380 Mar. 2015
  • Association between serum IgG4 concentrations and the morphology of the aorta in patients who undergo cardiac computed tomography.
    Sakamoto A, Ishizaka N, Imai Y, Uehara M, Ando J, Nagai R, Komuro I
    Journal of cardiology 65(2) 150-156 Feb. 2015
  • Pioglitazone Reduces Vascular Lipid Accumulation in Angiotensin II-Induced Hypertensive Rat.
    Sakamoto A, Higashikuni Y, Hongo M, Imai Y, Koike K, Nagai R, Komuro I, Ishizaka N
    Journal of atherosclerosis and thrombosis 22(12) 1225-1234 2015
  • A Case of Adult-Onset Acute Rheumatic Fever With Long-Lasting Atrioventricular Block Requiring Permanent Pacemaker Implantation.
    Oba Y, Watanabe H, Nishimura Y, Ueno S, Nagashima T, Imai Y, Shimpo M, Kario K
    International heart journal 56(6) 664-667 2015
  • Pathophysiology and Japanese clinical characteristics in Marfan syndrome.
    Fujita D, Takeda N, Imai Y, Inuzuka R, Komuro I, Hirata Y
    Pediatrics international : official journal of the Japan Pediatric Society 56(4) 484-491 Aug. 2014
  • Impairment of flow-mediated dilation correlates with aortic dilation in patients with Marfan syndrome.
    Takata M, Amiya E, Watanabe M, Omori K, Imai Y, Fujita D, Nishimura H, Kato M, Morota T, Nawata K, Ozeki A, Watanabe A, Kawarasaki S, Hosoya Y, Nakao T, Maemura K, Nagai R, Hirata Y, Komuro I
    Heart and vessels 29(4) 478-485 Jul. 2014
  • Impacts of patient characteristics on the effectiveness of landiolol in AF/AFL patients complicated with LV dysfunction: Subgroup analysis of the J-Land study.
    Kinugawa K, Nagai R, Inoue H, Atarashi H, Seino Y, Yamashita T, Shimizu W, Aiba T, Kitakaze M, Sakamoto A, Ikeda T, Imai Y, Daimon T, Fujino K, Nagano T, Okamura T, Hori M, J-Land Investigators.
    Advances in therapy 31(4) 426-439 Apr. 2014
  • Temporary dual-chamber pacing can stabilize hemodynamics during noncardiac surgery in a patient with left ventricular hypertrophy and outflow obstruction.
    Kojima T, Imai Y, Tsushima K, Uno K, Fujiu K, Iiri T, Nishimatsu H, Suzuki T, Sugiyama H, Asada K, Nakao T, Yamashita H, Hirata Y, Nagai R
    Journal of cardiothoracic and vascular anesthesia 28(1) 124-127 Feb. 2014
  • Giant coronary arteriovenous fistula between left superior pulmonary vein and left atrial appendage.
    Kojima T, Imai Y, Komuro I
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 16(1) 39 Jan. 2014
  • Association of serum IgG4 and soluble interleukin-2 receptor levels with epicardial adipose tissue and coronary artery calcification.
    Sakamoto A, Ishizaka N, Imai Y, Ando J, Nagai R, Komuro I
    Clinica chimica acta; international journal of clinical chemistry 428 63-69 Jan. 2014
  • Periodontitis in cardiovascular disease patients with or without Marfan syndrome--a possible role of Prevotella intermedia.
    Suzuki J, Imai Y, Aoki M, Fujita D, Aoyama N, Tada Y, Wakayama K, Akazawa H, Izumi Y, Isobe M, Komuro I, Nagai R, Hirata Y
    PloS one 9(4) e95521 2014
  • Association of serum IgG4 and soluble interleukin-2 receptor levels with epicardial adipose tissue and coronary artery calcification.
    Sakamoto A, Ishizaka N, Imai Y, Ando J, Nagai R, Komuro I
    Clinica chimica acta; international journal of clinical chemistry Oct. 2013
  • An elevated cibenzoline level interacted with cyclosporine caused ventricular tachyarrhythmia and high defibrillation threshold in hypertrophic cardiomyopathy.
    Kojima T, Imai Y, Fujiu K, Asada K, Ando J, Watanabe M, Yamashita H, Komuro I
    International journal of cardiology 168(1) e24-6 Sep. 2013
  • VEGF-A induces its negative regulator, soluble form of VEGFR-1, by modulating its alternative splicing.
    Saito T, Takeda N, Amiya E, Nakao T, Abe H, Semba H, Soma K, Koyama K, Hosoya Y, Imai Y, Isagawa T, Watanabe M, Manabe I, Komuro I, Nagai R, Maemura K
    FEBS letters 587(14) 2179-2185 Jul. 2013
  • Angiotensin II impairs endothelial nitric-oxide synthase bioavailability under free cholesterol-enriched conditions via intracellular free cholesterol-rich membrane microdomains.
    Amiya E, Watanabe M, Takeda N, Saito T, Shiga T, Hosoya Y, Nakao T, Imai Y, Manabe I, Nagai R, Komuro I, Maemura K
    The Journal of biological chemistry 288(20) 14497-14509 May 2013
  • Aortic valve replacement for aortic stenosis caused by alkaptonuria.
    Hiroyoshi J, Saito A, Panthee N, Imai Y, Kawashima D, Motomura N, Ono M
    The Annals of thoracic surgery 95(3) 1076-1079 Mar. 2013
  • Patient specific simulation of body surface ECG using the finite element method.
    Okada J, Sasaki T, Washio T, Yamashita H, Kariya T, Imai Y, Nakagawa M, Kadooka Y, Nagai R, Hisada T, Sugiura S
    Pacing and clinical electrophysiology : PACE 36(3) 309-321 Mar. 2013
  • Circulating transforming growth factor β-1 level in Japanese patients with Marfan syndrome.
    Ogawa N, Imai Y, Nishimura H, Kato M, Takeda N, Nawata K, Taketani T, Morota T, Takamoto S, Nagai R, Hirata Y
    International heart journal 54(1) 23-26 2013
  • Urgent management of rapid heart rate in patients with atrial fibrillation/flutter and left ventricular dysfunction: comparison of the ultra-short-acting β1-selective blocker landiolol with digoxin (J-Land Study).
    Nagai R, Kinugawa K, Inoue H, Atarashi H, Seino Y, Yamashita T, Shimizu W, Aiba T, Kitakaze M, Sakamoto A, Ikeda T, Imai Y, Daimon T, Fujino K, Nagano T, Okamura T, Hori M, J-Land Investigators.
    Circulation journal : official journal of the Japanese Circulation Society 77(4) 908-916 2013
  • Radiofrequency catheter ablation of the accessory pathway adversely affected the left ventricular outflow tract pressure gradient in a patient with hypertrophic obstructive cardiomyopathy.
    Nakayama A, Takahashi M, Hina K, Fujiu K, Sugiyama H, Kojima T, Ando J, Imai Y, Hirata Y, Nagai R
    International heart journal 54(2) 111-114 2013
  • Associations of variations in the MRF2/ARID5B gene with susceptibility to type 2 diabetes in the Japanese population.
    Wang G, Watanabe M, Imai Y, Hara K, Manabe I, Maemura K, Horikoshi M, Ozeki A, Itoh C, Sugiyama T, Kadowaki T, Yamazaki T, Nagai R
    Journal of human genetics 57(11) 727-733 Nov. 2012
  • Early decision for a left ventricular assist device implantation is necessary for patients with modifier A.
    Imamura T, Kinugawa K, Shiga T, Endo M, Inaba T, Maki H, Hatano M, Imai Y, Yao A, Hirata Y, Nishimura T, Kyo S, Ono M, Nagai R
    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 15(3) 301-304 Sep. 2012
  • Depressive symptoms are common and associated with adverse clinical outcomes in heart failure with reduced and preserved ejection fraction.
    Kato N, Kinugawa K, Shiga T, Hatano M, Takeda N, Imai Y, Watanabe M, Yao A, Hirata Y, Kazuma K, Nagai R
    Journal of cardiology 60(1) 23-30 Jul. 2012
  • Serum levels of IgG4 and soluble interleukin-2 receptor in patients with abdominal and thoracic aortic aneurysm who undergo coronary angiography.
    Sakamoto A, Ishizaka N, Imai Y, Nagai R
    Atherosclerosis 221(2) 602-603 Apr. 2012
  • Multifocal fibrosclerosis and IgG4-related disease involving the cardiovascular system.
    Ishizaka N, Sakamoto A, Imai Y, Terasaki F, Nagai R
    Journal of cardiology 59(2) 132-138 Mar. 2012
  • Serum levels of IgG4 and soluble interleukin-2 receptor in patients with coronary artery disease.
    Sakamoto A, Ishizaka N, Saito K, Imai Y, Morita H, Koike K, Kohro T, Nagai R
    Clinica chimica acta; international journal of clinical chemistry 413(5-6) 577-581 Mar. 2012
  • Idiopathic retroperitoneal fibrosis, inflammatory aortic aneurysm, and inflammatory pericarditis--retrospective analysis of 11 case histories.
    Sakamoto A, Nagai R, Saito K, Imai Y, Takahashi M, Hosoya Y, Takeda N, Hirano K, Koike K, Enomoto Y, Kume H, Homma Y, Maeda D, Yamada H, Fukayama M, Hirata Y, Ishizaka N
    Journal of cardiology 59(2) 139-146 Mar. 2012
  • Intrathoracic impedance monitoring in patients with heart failure: correlation with dehydration and bleeding events.
    Asada K, Fujiu K, Imai Y, Kojima T, Sugiyama H, Suzuki T, Kinugawa K, Hirata Y, Nagai R
    Circulation journal : official journal of the Japanese Circulation Society 76(11) 2592-2598 2012
  • An infant with heart failure due to ventricular dyssynchrony and refractory tachycardia caused by a right anterolateral accessory pathway.
    Suzuki Y, Suzuki T, Imai Y, Inuzuka R, Suzuki T, Nakamura Y, Ono H
    Cardiology 123(2) 108-112 2012
  • Evaluating Japanese patients with the Marfan syndrome using high-throughput microarray-based mutational analysis of fibrillin-1 gene.
    Ogawa N, Imai Y, Takahashi Y, Nawata K, Hara K, Nishimura H, Kato M, Takeda N, Kohro T, Morita H, Taketani T, Morota T, Yamazaki T, Goto J, Tsuji S, Takamoto S, Nagai R, Hirata Y
    The American journal of cardiology 108(12) 1801-1807 Dec. 2011
  • IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension.
    Tsushima K, Osawa T, Yanai H, Nakajima A, Takaoka A, Manabe I, Ohba Y, Imai Y, Taniguchi T, Nagai R
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology 25(5) 1531-1543 May 2011
  • Translation and validation study of the Japanese versions of the Coronary Revascularisation Outcome Questionnaire (CROQ-J).
    Seki S, Kato N, Ito N, Kinugawa K, Ono M, Motomura N, Yao A, Watanabe M, Imai Y, Takeda N, Inoue M, Hatano M, Kazuma K
    European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology 10(1) 22-30 Mar. 2011
  • Diagnostic efficacy of coronary CT angiography as a follow-up modality for procedure-related coronary dissection.
    Hasumi E, Iwata H, Saito K, Fujiu K, Ando J, Imai Y, Fujita H, Hirata Y, Nagai R
    International heart journal 52(4) 240-242 2011
  • Plasma cystatin C concentration reflects the severity of coronary artery disease in patients without chronic kidney disease.
    Kiyosue A, Hirata Y, Ando J, Fujita H, Morita T, Takahashi M, Nagata D, Kohro T, Imai Y, Nagai R
    Circulation journal : official journal of the Japanese Circulation Society 74(11) 2441-2447 Nov. 2010
  • Genome-wide association study of coronary artery disease.
    Ogawa N, Imai Y, Morita H, Nagai R
    International journal of hypertension 2010 790539 Sep. 2010
  • Validity and reliability of Seattle angina questionnaire Japanese version in patients with coronary artery disease.
    Seki S, Kato N, Ito N, Kinugawa K, Ono M, Motomura N, Yao A, Watanabe M, Imai Y, Takeda N, Inoue M, Hatano M, Kazuma K
    Asian nursing research 4(2) 57-63 Jul. 2010
  • Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.
    Oishi Y, Manabe I, Imai Y, Hara K, Horikoshi M, Fujiu K, Tanaka T, Aizawa T, Kadowaki T, Nagai R
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24(6) 1780-1788 Jun. 2010
  • Relationship between renal dysfunction and severity of coronary artery disease in Japanese patients.
    Kiyosue A, Hirata Y, Ando J, Fujita H, Morita T, Takahashi M, Nagata D, Kohro T, Imai Y, Nagai R
    Circulation journal : official journal of the Japanese Circulation Society 74(4) 786-791 Apr. 2010
  • Successful catheter ablation of atrial tachycardia and atrial fibrillation in persistent left superior vena cava.
    Tsutsui K, Ajiki K, Fujiu K, Imai Y, Hayami N, Murakawa Y
    International heart journal 51(1) 72-74 Jan. 2010
  • Surgical repair for unguarded tricuspid orifice: our successful experience using the Fontan procedure with total right ventricular exclusion.
    Kariya T, Imai Y, Murakami A
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 36(3) 603; author reply 604 Sep. 2009
  • Adherence to self-care behavior and factors related to this behavior among patients with heart failure in Japan.
    Kato N, Kinugawa K, Ito N, Yao A, Watanabe M, Imai Y, Takeda N, Hatano M, Kazuma K
    Heart & lung : the journal of critical care 38(5) 398-409 Sep. 2009
  • Infective endocarditis by Bartonella quintana masquerading as antineutrophil cytoplasmic antibody-associated small vessel vasculitis.
    Sugiyama H, Sahara M, Imai Y, Ono M, Okamoto K, Kikuchi K, Nagai R
    Cardiology 114(3) 208-211 2009
  • Images in cardiovascular medicine. Markedly dilated right heart 17 years after initial treatment repaired by total right ventricular exclusion and total cavopulmonary connection.
    Kariya T, Imai Y, Murakami A, Minegishi S, Katori T, Kato H, Ajiki K, Hirata Y, Nagai R
    Circulation 118(9) e133-5 Aug. 2008
  • Manganese superoxide dismutase polymorphism affects the oxidized low-density lipoprotein-induced apoptosis of macrophages and coronary artery disease.
    Fujimoto H, Taguchi J, Imai Y, Ayabe S, Hashimoto H, Kobayashi H, Ogasawara K, Aizawa T, Yamakado M, Nagai R, Ohno M
    European heart journal 29(10) 1267-1274 May 2008
  • Genetic variations of Mrf-2/ARID5B confer risk of coronary atherosclerosis in the Japanese population.
    Wang G, Watanabe M, Imai Y, Hara K, Manabe I, Maemura K, Horikoshi M, Kohro T, Amiya E, Sugiyama T, Fujita T, Kadowaki T, Yamazaki T, Nagai R
    International heart journal 49(3) 313-327 May 2008
  • Promoter region-specific histone incorporation by the novel histone chaperone ANP32B and DNA-binding factor KLF5.
    Munemasa Y, Suzuki T, Aizawa K, Miyamoto S, Imai Y, Matsumura T, Horikoshi M, Nagai R
    Molecular and cellular biology 28(3) 1171-1181 Feb. 2008
  • Thrombomodulin is a clock-controlled gene in vascular endothelial cells.
    Takeda N, Maemura K, Horie S, Oishi K, Imai Y, Harada T, Saito T, Shiga T, Amiya E, Manabe I, Ishida N, Nagai R
    The Journal of biological chemistry 282(45) 32561-32567 Nov. 2007
  • A case of neonatal lupus erythematosus presenting delayed dilated cardiomyopathy with circulating autoantibody to annexin A6.
    Seko Y, Matsumoto A, Fukuda T, Imai Y, Fujimura T, Taka H, Mineki R, Murayama K, Hirata Y, Nagai R
    International heart journal 48(3) 407-415 May 2007
  • Reduced adiponectin level is associated with severity of coronary artery disease.
    Hara K, Yamauchi T, Imai Y, Manabe I, Nagai R, Kadowaki T
    International heart journal 48(2) 149-153 Mar. 2007
  • Supraventricular tachycardia originating from the posterior atrioventricular node in the univentricular heart with single atrium.
    Ajiki K, Hayami N, Kasaoka Y, Imai Y, Fujiu K, Murakawa Y
    International heart journal 48(2) 253-259 Mar. 2007
  • New insights in the treatment strategy for pulmonary arterial hypertension.
    Sahara M, Takahashi T, Imai Y, Nakajima T, Yao A, Morita T, Hirata Y, Nagai R
    Cardiovascular drugs and therapy 20(5) 377-386 Oct. 2006
  • DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation.
    Nishimura G, Manabe I, Tsushima K, Fujiu K, Oishi Y, Imai Y, Maemura K, Miyagishi M, Higashi Y, Kondoh H, Nagai R
    Developmental cell 11(1) 93-104 Jul. 2006
  • Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.
    Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T
    Diabetes care 29(6) 1357-1362 Jun. 2006
  • C-reactive protein induces VCAM-1 gene expression through NF-kappaB activation in vascular endothelial cells.
    Kawanami D, Maemura K, Takeda N, Harada T, Nojiri T, Saito T, Manabe I, Imai Y, Nagai R
    Atherosclerosis 185(1) 39-46 Mar. 2006
  • Subarachnoid hemorrhage from mycotic aneurysms.
    Shimizu T, Takeda N, Takahashi M, Imai Y, Ishizaka N, Hirata Y, Nagai R
    Internal medicine (Tokyo, Japan) 45(20) 1189-1190 2006
  • The use of a supercooling refrigerator improves the preservation of organ grafts.
    Monzen K, Hosoda T, Hayashi D, Imai Y, Okawa Y, Kohro T, Uozaki H, Nishiyama T, Fukayama M, Nagai R
    Biochemical and biophysical research communications 337(2) 534-539 Nov. 2005
  • Genetic analysis in a patient with recurrent cardiac myxoma and endocrinopathy.
    Imai Y, Taketani T, Maemura K, Takeda N, Harada T, Nojiri T, Kawanami D, Monzen K, Hayashi D, Murakawa Y, Ohno M, Hirata Y, Yamazaki T, Takamoto S, Nagai R
    Circulation journal : official journal of the Japanese Circulation Society 69(8) 994-995 Aug. 2005
  • Altered patterns of gene expression specific to thoracic aortic aneurysms: microarray analysis of surgically resected specimens.
    Taketani T, Imai Y, Morota T, Maemura K, Morita H, Hayashi D, Yamazaki T, Nagai R, Takamoto S
    International heart journal 46(2) 265-277 Mar. 2005
  • Atrial natriuretic peptide inhibits cardiomyocyte hypertrophy through mitogen-activated protein kinase phosphatase-1.
    Hayashi D, Kudoh S, Shiojima I, Zou Y, Harada K, Shimoyama M, Imai Y, Monzen K, Yamazaki T, Yazaki Y, Nagai R, Komuro I
    Biochemical and biophysical research communications 322(1) 310-319 Sep. 2004
  • Convenient single-nucleotide polymorphism typing from whole blood by probe extension and bioluminescence detection.
    Nakashima Y, Okano K, Kojima K, Shirakura H, Ishida S, Watanabe M, Maeda K, Tsunoda H, Imai Y, Nagai K
    Clinical chemistry 50(8) 1417-1420 Aug. 2004
  • Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.
    Takeda N, Maemura K, Imai Y, Harada T, Kawanami D, Nojiri T, Manabe I, Nagai R
    Circulation research 95(2) 146-153 Jul. 2004
  • Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.
    Ikeda Y, Imai Y, Kumagai H, Nosaka T, Morikawa Y, Hisaoka T, Manabe I, Maemura K, Nakaoka T, Imamura T, Miyazono K, Komuro I, Nagai R, Kitamura T
    Proceedings of the National Academy of Sciences of the United States of America 101(29) 10732-10737 Jul. 2004
  • Development of a pioneering clinical support system utilizing information technology.
    Hayashi D, Imai Y, Morita H, Fujita H, Monzen K, Harada T, Nojiri T, Yamazaki T, Yamazaki T, Nagai R
    Japanese heart journal 45(2) 315-324 Mar. 2004
  • Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions.
    Kawanami D, Maemura K, Takeda N, Harada T, Nojiri T, Imai Y, Manabe I, Utsunomiya K, Nagai R
    Biochemical and biophysical research communications 314(2) 415-419 Feb. 2004
  • Carvedilol therapy improved left ventricular function in a patient with arrhythmogenic right ventricular cardiomyopathy.
    Hiroi Y, Fujiu K, Komatsu S, Sonoda M, Sakomura Y, Imai Y, Oishi Y, Nakamura F, Ajiki K, Hayami N, Murakawa Y, Ohno M, Hirata Y, Ohtomo K, Nagai R
    Japanese heart journal 45(1) 169-177 Jan. 2004
  • Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain.
    Miyamoto S, Suzuki T, Muto S, Aizawa K, Kimura A, Mizuno Y, Nagino T, Imai Y, Adachi N, Horikoshi M, Nagai R
    Molecular and cellular biology 23(23) 8528-8541 Dec. 2003
  • Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese.
    Nojiri T, Morita H, Imai Y, Maemura K, Ohno M, Ogasawara K, Aizawa T, Saito A, Hayashi D, Hirata Y, Sugiyama T, Yamazaki T, Nagai R
    International journal of cardiology 92(2-3) 181-186 Dec. 2003
  • [Endoscopic diagnosis of early colorectal cancer].
    Yamano HO, Imai Y, Maeda S, Nakazato M, Matsushita HO, Yamanaka Y, Sato K
    Nihon rinsho. Japanese journal of clinical medicine 61 Suppl 7 156-163 Sep. 2003
  • A common Ile 823 Met variant of ATP-binding cassette transporter A1 gene (ABCA1) alters high density lipoprotein cholesterol level in Japanese population.
    Harada T, Imai Y, Nojiri T, Morita H, Hayashi D, Maemura K, Fukino K, Kawanami D, Nishimura G, Tsushima K, Monzen K, Yamazaki T, Mitsuyama S, Shintani T, Watanabe N, Seto K, Sugiyama T, Nakamura F, Ohno M, Hirata Y, Yamazaki T, Nagai R
    Atherosclerosis 169(1) 105-112 Jul. 2003
  • Deficiency of protein S-mediated familial venous thrombophilia--a case report.
    Harada T, Morita H, Imai Y, Hayashi D, Takeda N, Maemura K, Yazaki Y, Nagai R
    Angiology 54(3) 377-381 May 2003
  • Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis.
    Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Takakuwa K, Matsui J, Takata M, Eto K, Terauchi Y, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Naitoh T, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T
    The Journal of biological chemistry 278(4) 2461-2468 Jan. 2003
  • Establishment of a method of anonymization of DNA samples in genetic research.
    Hara K, Ohe K, Kadowaki T, Kato N, Imai Y, Tokunaga K, Nagai R, Omata M
    Journal of human genetics 48(6) 327-330 2003
  • Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.
    Shindo T, Manabe I, Fukushima Y, Tobe K, Aizawa K, Miyamoto S, Kawai-Kowase K, Moriyama N, Imai Y, Kawakami H, Nishimatsu H, Ishikawa T, Suzuki T, Morita H, Maemura K, Sata M, Hirata Y, Komukai M, Kagechika H, Kadowaki T, Kurabayashi M, Nagai R
    Nature medicine 8(8) 856-863 Aug. 2002
  • Resistance to neointimal hyperplasia and fatty streak formation in mice with adrenomedullin overexpression.
    Imai Y, Shindo T, Maemura K, Sata M, Saito Y, Kurihara Y, Akishita M, Osuga J, Ishibashi S, Tobe K, Morita H, Oh-hashi Y, Suzuki T, Maekawa H, Kangawa K, Minamino N, Yazaki Y, Nagai R, Kurihara H
    Arteriosclerosis, thrombosis, and vascular biology 22(8) 1310-1315 Aug. 2002
  • A 70-year-old woman with cardiogenic shock and change in acute electrocardiogram patterns. Left main shock syndrome/acute LMT occlusion.
    Harada T, Ohtaki E, Asano R, Imai Y, Sumiyoshi T
    Journal of cardiology 40(1) 37-40 Jul. 2002
  • Evidence for association between paraoxonase gene polymorphisms and atherosclerotic diseases.
    Imai Y, Morita H, Kurihara H, Sugiyama T, Kato N, Ebihara A, Hamada C, Kurihara Y, Shindo T, Oh-hashi Y, Yazaki Y
    Atherosclerosis 149(2) 435-442 Apr. 2000
  • Mid-term follow-up of coronary artery aneurysm after directional coronary atherectomy.
    Imai Y, Hara K, Yamasaki M, Kozuma K, Nakajima H, Hara H, Saeki F, Tamura T
    Journal of cardiology 33(4) 201-208 Apr. 1999
  • Serum levels of vascular endothelial growth factor in patients with acute myocardial infarction undergoing reperfusion therapy.
    Seko Y, Imai Y, Suzuki S, Kamijukkoku S, Hayasaki K, Sakomura Y, Tobe K, Kadowaki T, Maekawa H, Takahashi N, Yazaki Y
    Clinical science (London, England : 1979) 92(5) 453-454 May 1997

Papers(other)

  • A successful case of severe right ventricular failure with congenitally corrected transposition of the great arteries using cardiac resynchronization therapy
    Saga Akiko, Imai Yasushi, Sugiyama Hiroaki, Kojima Toshiya, Fujiu Katsuhito, Ebihara Aya, Ajiki Kousuke, Kinugawa Kouichirou, Yamashita Hiroshi, Hirata Yasunobu, Nagai Ryozo
    Shinzo 43(5) 670-677 2011
  • A case of the most severe heart failure with congenitally corrected transposition of great arteries and dextrocardia who was successfully treated by cardiac resynchronization therapy
    SUGIYAMA Hiroaki, IMAI Yasushi, EBIHARA Aya, FUJIU Katsuhito, HIRATA Yasunobu, NAGAI Ryozo, TANAKA Nobuhiro, YAMASHINA Akira
    Japanese Journal of Electrocardiology 30(1) 63-72 Mar. 2010
  • Aortic Disease - Aortic Dissection and Thoracoabdominal Aortic Aneurysm; Progress in Diagnosis and Treatment.
    Imai Yasushi, Nagai Ryozo
    Nihon Naika Gakkai Zasshi 99(2) 219-221 Feb. 2010
  • A successfully-resuscitated young case of cardiopulmonary arrest due to ventricular fibrillation during american football practice : proposing effective use of the AED
    SUGIYAMA Hiroaki, IMAI Yasushi, FUJIU Katsuhito, IWATA Hiroshi, HIRATA Yasunobu, NAGAI Ryozo
    Japanese Journal of Electrocardiology 29(4) 298-305 Oct. 2009
  • Subacute endocardititis caused by Bartonella quintana simulating antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis
    Sugiyama Hiroaki, Sahara Makoto, Imai Yasushi, Matsuoka Rie, Hiroi Yukio, Hirata Yasunobu, Nagai Ryozo, Ono Minoru, Takamoto Shinichi, Okamoto Kou, Koike Kazuhiko, Kikuchi Ken
    Shinzo 41(10) 1102-1108 Oct. 2009
  • Clinical Data Retrieval System
    SETO K, SHINTANI T, SAITO A, FUJIO M, MITSUYAMA S, IMAI Y, HAYASHI D, NAGAI R
    25(2) 99-105 Nov. 2005
  • Successful Treatment of Splenomegaly and Anemia by VP Therapy in Idiopathic Myelofibrosis Complicated with Acromegaly:A Case Report
    IMAI Yasushi, AKIYAMA Nobu, HANAZONO Yutaka, INAMORI Ken, MITANI Kinuko, HIRAI Hisamaru, NAGAI Ryozo, YAZAKI Yoshio
    Japanese Journal of Clinical Hematology 36(10) 1233-1236 Oct. 1995
Display all
Papers(other)close
  • A successful case of severe right ventricular failure with congenitally corrected transposition of the great arteries using cardiac resynchronization therapy
    Saga Akiko, Imai Yasushi, Sugiyama Hiroaki, Kojima Toshiya, Fujiu Katsuhito, Ebihara Aya, Ajiki Kousuke, Kinugawa Kouichirou, Yamashita Hiroshi, Hirata Yasunobu, Nagai Ryozo
    Shinzo 43(5) 670-677 2011
  • A case of the most severe heart failure with congenitally corrected transposition of great arteries and dextrocardia who was successfully treated by cardiac resynchronization therapy
    SUGIYAMA Hiroaki, IMAI Yasushi, EBIHARA Aya, FUJIU Katsuhito, HIRATA Yasunobu, NAGAI Ryozo, TANAKA Nobuhiro, YAMASHINA Akira
    Japanese Journal of Electrocardiology 30(1) 63-72 Mar. 2010
  • Aortic Disease - Aortic Dissection and Thoracoabdominal Aortic Aneurysm; Progress in Diagnosis and Treatment.
    Imai Yasushi, Nagai Ryozo
    Nihon Naika Gakkai Zasshi 99(2) 219-221 Feb. 2010
  • A successfully-resuscitated young case of cardiopulmonary arrest due to ventricular fibrillation during american football practice : proposing effective use of the AED
    SUGIYAMA Hiroaki, IMAI Yasushi, FUJIU Katsuhito, IWATA Hiroshi, HIRATA Yasunobu, NAGAI Ryozo
    Japanese Journal of Electrocardiology 29(4) 298-305 Oct. 2009
  • Subacute endocardititis caused by Bartonella quintana simulating antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis
    Sugiyama Hiroaki, Sahara Makoto, Imai Yasushi, Matsuoka Rie, Hiroi Yukio, Hirata Yasunobu, Nagai Ryozo, Ono Minoru, Takamoto Shinichi, Okamoto Kou, Koike Kazuhiko, Kikuchi Ken
    Shinzo 41(10) 1102-1108 Oct. 2009
  • Clinical Data Retrieval System
    SETO K, SHINTANI T, SAITO A, FUJIO M, MITSUYAMA S, IMAI Y, HAYASHI D, NAGAI R
    25(2) 99-105 Nov. 2005
  • Successful Treatment of Splenomegaly and Anemia by VP Therapy in Idiopathic Myelofibrosis Complicated with Acromegaly:A Case Report
    IMAI Yasushi, AKIYAMA Nobu, HANAZONO Yutaka, INAMORI Ken, MITANI Kinuko, HIRAI Hisamaru, NAGAI Ryozo, YAZAKI Yoshio
    Japanese Journal of Clinical Hematology 36(10) 1233-1236 Oct. 1995


Copyright c MEDIA FUSION Co.,Ltd. All rights reserved.