YAMAGATA Takanori

FacultyPediatricsDevelopmentalMedicine
Job titleProfessorWeb site

Profile

Research Keywords

    pediatrics, pediatric neurology, developmental disorder, human genetics, neuroscience, New Science in General

Research Areas

  • Clinical internal medicine / Pediatrics
  • Basic medicine / Human genetics
  • Neuroscience / Neuroscience in general

Career

  • Nov.1997
    -
    Mar.2000
    Departement of Molecular and Human Genetics, research fellow
  • May2011
    -
    Today
    Department of Pediatrics, Jichi Medical University, Professor
  • 1997
    -
    2000
    Research Associate, Department of Molecular
  • and Human Genetics, Baylor College of
  • Medicine, USA

Academic Background

  • -
    1986
    Faculty of Medicine, Gifu University (japan)

Academic Societies

  • JAPANESE SOCIETY FOR INHERITED METABOLIC DISEASES
  • The Japan Society of Pediatric Genetics
  • JAPANESE SOCIETY OF NEUROLOGY
  • Japanese Society for Neuroinfectious Diseases
  • Japanese Society for Mass-screening
  • JAPAN PEDIATRIC SOCIETY
  • THE JAPANESE SOCIETY OF CHILD NEUROLOGY
  • THE JAPAN SOCIETY OF HUMAN GENETICS
  • The Japan Epilepsy Society
  • The American Society of Human Gevetics
Display all
Academic Societiesclose
  • JAPANESE SOCIETY FOR INHERITED METABOLIC DISEASES
  • The Japan Society of Pediatric Genetics
  • JAPANESE SOCIETY OF NEUROLOGY
  • Japanese Society for Neuroinfectious Diseases
  • Japanese Society for Mass-screening
  • JAPAN PEDIATRIC SOCIETY
  • THE JAPANESE SOCIETY OF CHILD NEUROLOGY
  • THE JAPAN SOCIETY OF HUMAN GENETICS
  • The Japan Epilepsy Society
  • The American Society of Human Gevetics

Research Activities

Papers(paper)

  • MAOA/B deletion syndrome in male siblings with severe developmental delay and sudden loss of muscle tonus.
    Saito M, Yamagata T, Matsumoto A, Shiba Y, Nagashima M, Taniguchi S, Jimbo E, Momoi MY
    Brain & development Feb. 2013
  • A novel adult case of juvenile-onset Alexander disease: complete remission of neurological symptoms for over 12 years, despite insidiously progressive cervicomedullary atrophy.
    Namekawa M, Takiyama Y, Honda J, Sakoe K, Naoi T, Shimazaki H, Yamagata T, Momoi MY, Nakano I
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 33 1389-1392 Dec. 2012
  • Late-onset Leigh syndrome with myoclonic epilepsy with ragged-red fibers.
    Monden Y, Mori M, Kuwajima M, Goto T, Yamagata T, Momoi MY
    Brain & development Sep. 2012
  • Contiguous ABCD1 DXS1357E deletion syndrome: Report of an autopsy case.
    Iwasa M, Yamagata T, Mizuguchi M, Itoh M, Matsumoto A, Hironaka M, Honda A, Momoi MY, Shimozawa N
    Neuropathology : official journal of the Japanese Society of Neuropathology Sep. 2012
  • Clinically-oriented monitoring of acute effects of methylphenidate on cerebral hemodynamics in ADHD children using fNIRS.
    Monden Y, Dan H, Nagashima M, Dan I, Kyutoku Y, Okamoto M, Yamagata T, Momoi MY, Watanabe E
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 123(6) 1147-1157 Jun. 2012
  • A case of ADEM with atypical MRI findings of a centrally-located long spinal cord lesion.
    Monden Y, Yamagata T, Kuroiwa Y, Takahashi T, Mori M, Fukuda T, Sugie H, Momoi MY
    Brain & development 34 380-383 May 2012
  • Epidemiology of acute encephalopathy in Japan, with emphasis on the association of viruses and syndromes.
    Hoshino A, Saitoh M, Oka A, Okumura A, Kubota M, Saito Y, Takanashi J, Hirose S, Yamagata T, Yamanouchi H, Mizuguchi M
    Brain & development 34(5) 337 May 2012
  • Another promising treatment option for neuroblastoma-associated opsoclonus-myoclonus syndrome by oral high-dose dexamethasone pulse: lymphocyte markers as disease activity.
    Oguma M, Morimoto A, Takada A, Kashii Y, Fukuda T, Mori M, Yamagata T, Sugie H, Momoi MY
    Brain & development 34(3) 251-254 Mar. 2012
  • Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.
    Tsurusaki Y, Okamoto N, Ohashi H, Kosho T, Imai Y, Hibi-Ko Y, Kaname T, Naritomi K, Kawame H, Wakui K, Fukushima Y, Homma T, Kato M, Hiraki Y, Yamagata T, Yano S, Mizuno S, Sakazume S, Ishii T, Nagai T, Shiina M, Ogata K, Ohta T, Niikawa N, Miyatake S, Okada I, Mizuguchi T, Doi H, Saitsu H, Miyake N, Matsumoto N
    Nature genetics 44 376-378 Mar. 2012
  • Mutation in Parkinson disease-associated, G-protein-coupled receptor 37 (GPR37/PaelR) is related to Autism spectrum disorder.
    Fujita-Jimbo E, Yu ZL, Li H, Yamagata T, Mori M, Momoi T, Momoi MY
    PloS one 7 e51155 2012
Display all
Papers(paper)close
  • MAOA/B deletion syndrome in male siblings with severe developmental delay and sudden loss of muscle tonus.
    Saito M, Yamagata T, Matsumoto A, Shiba Y, Nagashima M, Taniguchi S, Jimbo E, Momoi MY
    Brain & development Feb. 2013
  • A novel adult case of juvenile-onset Alexander disease: complete remission of neurological symptoms for over 12 years, despite insidiously progressive cervicomedullary atrophy.
    Namekawa M, Takiyama Y, Honda J, Sakoe K, Naoi T, Shimazaki H, Yamagata T, Momoi MY, Nakano I
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 33 1389-1392 Dec. 2012
  • Late-onset Leigh syndrome with myoclonic epilepsy with ragged-red fibers.
    Monden Y, Mori M, Kuwajima M, Goto T, Yamagata T, Momoi MY
    Brain & development Sep. 2012
  • Contiguous ABCD1 DXS1357E deletion syndrome: Report of an autopsy case.
    Iwasa M, Yamagata T, Mizuguchi M, Itoh M, Matsumoto A, Hironaka M, Honda A, Momoi MY, Shimozawa N
    Neuropathology : official journal of the Japanese Society of Neuropathology Sep. 2012
  • Clinically-oriented monitoring of acute effects of methylphenidate on cerebral hemodynamics in ADHD children using fNIRS.
    Monden Y, Dan H, Nagashima M, Dan I, Kyutoku Y, Okamoto M, Yamagata T, Momoi MY, Watanabe E
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 123(6) 1147-1157 Jun. 2012
  • A case of ADEM with atypical MRI findings of a centrally-located long spinal cord lesion.
    Monden Y, Yamagata T, Kuroiwa Y, Takahashi T, Mori M, Fukuda T, Sugie H, Momoi MY
    Brain & development 34 380-383 May 2012
  • Epidemiology of acute encephalopathy in Japan, with emphasis on the association of viruses and syndromes.
    Hoshino A, Saitoh M, Oka A, Okumura A, Kubota M, Saito Y, Takanashi J, Hirose S, Yamagata T, Yamanouchi H, Mizuguchi M
    Brain & development 34(5) 337 May 2012
  • Another promising treatment option for neuroblastoma-associated opsoclonus-myoclonus syndrome by oral high-dose dexamethasone pulse: lymphocyte markers as disease activity.
    Oguma M, Morimoto A, Takada A, Kashii Y, Fukuda T, Mori M, Yamagata T, Sugie H, Momoi MY
    Brain & development 34(3) 251-254 Mar. 2012
  • Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.
    Tsurusaki Y, Okamoto N, Ohashi H, Kosho T, Imai Y, Hibi-Ko Y, Kaname T, Naritomi K, Kawame H, Wakui K, Fukushima Y, Homma T, Kato M, Hiraki Y, Yamagata T, Yano S, Mizuno S, Sakazume S, Ishii T, Nagai T, Shiina M, Ogata K, Ohta T, Niikawa N, Miyatake S, Okada I, Mizuguchi T, Doi H, Saitsu H, Miyake N, Matsumoto N
    Nature genetics 44 376-378 Mar. 2012
  • Mutation in Parkinson disease-associated, G-protein-coupled receptor 37 (GPR37/PaelR) is related to Autism spectrum disorder.
    Fujita-Jimbo E, Yu ZL, Li H, Yamagata T, Mori M, Momoi T, Momoi MY
    PloS one 7 e51155 2012
  • Elevated serum interleukin-7 level in idiopathic steroid-sensitive nephrotic syndrome.
    Kanai T, Shiraishi H, Yamagata T, Ito T, Odaka J, Saito T, Aoyagi J, Momoi MY
    Pediatrics international : official journal of the Japan Pediatric Society 53(6) 906-909 Dec. 2011
  • Foot process effacement with normal urinalysis in classic fabry disease.
    Kanai T, Yamagata T, Ito T, Odaka J, Saito T, Aoyagi J, Kobayashi M, Ohashi T, Ueda Y, Momoi MY
    JIMD reports 1 39-42 2011
  • Th2 cells predominate in idiopathic steroid-sensitive nephrotic syndrome.
    Kanai T, Shiraishi H, Yamagata T, Ito T, Odaka J, Saito T, Aoyagi J, Momoi MY
    Clinical and experimental nephrology 14(6) 578-583 Dec. 2010
  • Impairment of social and emotional behaviors in Cadm1-knockout mice.
    Takayanagi Y, Fujita E, Yu Z, Yamagata T, Momoi MY, Momoi T, Onaka T
    Biochemical and biophysical research communications 396(3) 703-708 Jun. 2010
  • Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay.
    Saitsu H, Tohyama J, Kumada T, Egawa K, Hamada K, Okada I, Mizuguchi T, Osaka H, Miyata R, Furukawa T, Haginoya K, Hoshino H, Goto T, Hachiya Y, Yamagata T, Saitoh S, Nagai T, Nishiyama K, Nishimura A, Miyake N, Komada M, Hayashi K, Hirai S, Ogata K, Kato M, Fukuda A, Matsumoto N
    American journal of human genetics 86(6) 881-891 Jun. 2010
  • Unilaterally and rapidly progressing white matter lesion and elevated cytokines in a patient with Tay-Sachs disease.
    Hayase T, Shimizu J, Goto T, Nozaki Y, Mori M, Takahashi N, Namba E, Yamagata T, Momoi MY
    Brain & development 32(3) 244-247 Mar. 2010
  • Expression analysis and mutation detection of DLX5 and DLX6 in autism.
    Nakashima N, Yamagata T, Mori M, Kuwajima M, Suwa K, Momoi MY
    Brain & development 32(2) 98-104 Feb. 2010
  • Various types of LRP5 mutations in four patients with osteoporosis-pseudoglioma syndrome: identification of a 7.2-kb microdeletion using oligonucleotide tiling microarray.
    Narumi S, Numakura C, Shiihara T, Seiwa C, Nozaki Y, Yamagata T, Momoi MY, Watanabe Y, Yoshino M, Matsuishi T, Nishi E, Kawame H, Akahane T, Nishimura G, Emi M, Hasegawa T
    American journal of medical genetics. Part A 152A 133-140 Jan. 2010
  • Metabolic and hemodynamic advantages of an acetate-free citrate dialysate in a uremic case of congenital methylmalonic acidemia.
    Saito T, Saito O, Maeda T, Ito C, Ando Y, Yamagata T, Muto S, Momoi M, Kusano E
    American journal of kidney diseases : the official journal of the National Kidney Foundation 54 764-769 Oct. 2009
  • Macrophage inflammatory protein-1beta and interleukin-8 associated with idiopathic steroid-sensitive nephrotic syndrome.
    Kanai T, Yamagata T, Momoi MY
    Pediatrics international : official journal of the Japan Pediatric Society 51(4) 443-447 Aug. 2009
  • Ehlers-Danlos type IV in pregnancy with a history of myocardial infarction.
    Ohkuchi A, Matsubara S, Takahashi K, Inoue S, Saito T, Mitsuhashi T, Yamagata T, Takahashi N, Watanabe A, Shimada T, Suzuki M
    The journal of obstetrics and gynaecology research 35(4) 797-800 Aug. 2009
  • Mutations in the gene encoding CADM1 are associated with autism spectrum disorder.
    Zhiling Y, Fujita E, Tanabe Y, Yamagata T, Momoi T, Momoi MY
    Biochemical and biophysical research communications 377(3) 926-929 Dec. 2008
  • [A child with generalized myasthenia gravis successfully treated with tacrolimus].
    Goto T, Mori M, Yamagata T, Mizuguchi M, Momoi MY
    No to hattatsu. Brain and development 39(4) 300-303 Jul. 2007
  • Elevated CSF IL-6 in a patient with respiratory syncytial virus encephalopathy.
    Otake Y, Yamagata T, Morimoto Y, Imi M, Mori M, Aihara T, Ichiyama T, Momoi MY
    Brain & development 29(2) 117-120 Mar. 2007
  • A case of meningoencephalitis associated with G1P[8] rotavirus infection in a Japanese child.
    Goto T, Kimura H, Numazaki K, Akiyama M, Kato M, Noda M, Nozaki Y, Tanaka-Taya K, Taniguchi K, Yamagata T, Nishio O, Oogane T, Momoi MY, Okabe N
    Scandinavian journal of infectious diseases 39 1067-1070 2007
  • Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior.
    Nishijima I, Yamagata T, Spencer CM, Weeber EJ, Alekseyenko O, Sweatt JD, Momoi MY, Ito M, Armstrong DL, Nelson DL, Paylor R, Bradley A
    Human molecular genetics 15 3241-3250 Nov. 2006
  • BAC array CGH reveals genomic aberrations in idiopathic mental retardation.
    Miyake N, Shimokawa O, Harada N, Sosonkina N, Okubo A, Kawara H, Okamoto N, Kurosawa K, Kawame H, Iwakoshi M, Kosho T, Fukushima Y, Makita Y, Yokoyama Y, Yamagata T, Kato M, Hiraki Y, Nomura M, Yoshiura K, Kishino T, Ohta T, Mizuguchi T, Niikawa N, Matsumoto N
    American journal of medical genetics. Part A 140 205-211 Feb. 2006
  • Mutation analysis of methyl-CpG binding protein family genes in autistic patients.
    Li H, Yamagata T, Mori M, Yasuhara A, Momoi MY
    Brain & development 27(5) 321-325 Aug. 2005
  • Early-onset ataxia with oculomotor apraxia with a novel APTX mutation.
    Ito A, Yamagata T, Mori M, Momoi MY
    Pediatric neurology 33 53-56 Jul. 2005
  • Two new XPD patients compound heterozygous for the same mutation demonstrate diverse clinical features.
    Fujimoto M, Leech SN, Theron T, Mori M, Fawcett H, Botta E, Nozaki Y, Yamagata T, Moriwaki S, Stefanini M, Momoi MY, Nakagawa H, Shuster S, Moss C, Lehmann AR
    The Journal of investigative dermatology 125 86-92 Jul. 2005
  • Absence of causative mutations and presence of autism-related allele in FOXP2 in Japanese autistic patients.
    Li H, Yamagata T, Mori M, Momoi MY
    Brain & development 27(3) 207-210 Apr. 2005
  • RSK2 gene mutations in Coffin-Lowry syndrome with drop episodes.
    Nakamura M, Yamagata T, Mori M, Momoi MY
    Brain & development 27(2) 114-117 Mar. 2005
  • Dichloroacetate treatment for mitochondrial cytopathy: long-term effects in MELAS.
    Mori M, Yamagata T, Goto T, Saito S, Momoi MY
    Brain & development 26 453-458 Oct. 2004
  • Beneficial effect of L-arginine for stroke-like episode in MELAS.
    Kubota M, Sakakihara Y, Mori M, Yamagata T, Momoi-Yoshida M
    Brain & development 26 481-3; discussion 480 Oct. 2004
  • Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.
    Gu Y, McIlwain KL, Weeber EJ, Yamagata T, Xu B, Antalffy BA, Reyes C, Yuva-Paylor L, Armstrong D, Zoghbi H, Sweatt JD, Paylor R, Nelson DL
    The Journal of neuroscience : the official journal of the Society for Neuroscience 22 2753-2763 Apr. 2002
  • Association of autism in two patients with hereditary multiple exostoses caused by novel deletion mutations of EXT1.
    Li H, Yamagata T, Mori M, Momoi MY
    Journal of human genetics 47(5) 262-265 2002
  • The human secretin gene: fine structure in 11p15.5 and sequence variation in patients with autism.
    Genomics 80:185-194 2002
  • Physical and genetic characterization reveals a pseudogene, an evolutionary junction, and unstable Loci in distal Xq28.
    Genomics 79:31-40 2002
  • Large expansion of the ATTCT pertanucleotide repeat in spinocerebellar ataxia type 10.(共著)
    Nature Genetics 26(2) 191-194 2000
  • Hepatocyte growth factor spesifically expressed in microglis activated ras in the neurons, similar to the action of neurotrophic factors
    Biochem. Biophys. Res. Commun. 210(1) 231-237 1995
  • Elastic fiber degeneration in Costello syndrome. (共著)
    Am. J. Med. Genet. 61(4) 304-309 1995
  • The changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos.
    Dev. Brain Res. 77(2) 163-176 1994
  • Distribution of retinoic acid receptor β protein in rat brain : up-requlation by retinoic acid.
    Biomed. Res. 14 183-190 1993
  • The expression of cellular retinoic acid binding protein (CRABP) in developing heart and skeletal muscles of mouse embryos. (共著)
    Biomed. Res. 12 105-112 1991
  • Expression of cellular retinoic acid binding pnotein in the developing nervous system of mouse embryo. (共著)
    Dev. Brain Res. 54 161-167 1990
  • Multi-institutional survey of the Aicardi Syndrome in Japan.
    Brain Dev. 12 760-765 1990
  • Ultrasonography and magnetic resonance imaging in Leigh disease.
    Ped. Neurol. 6 326-329 1990


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