hiraki toshiki

FacultyPhysiologyMolecularPhysiology&Biophysics
Job titleResearch AssociateWeb site

Profile

Research Areas

  • Biomolecular science / Biomolecular science

Research Activities

Papers(paper)

  • Loop L1 governs the DNA-binding specificity and order for RecA-catalyzed reactions in homologous recombination and DNA repair.
    Shinohara T, Ikawa S, Iwasaki W, Hiraki T, Hikima T, Mikawa T, Arai N, Kamiya N, Shibata T
    Nucleic acids research 43(2) 973-986 Jan. 2015
  • Pressure-induced endocytic degradation of the Saccharomyces cerevisiae low-affinity tryptophan permease Tat1 is mediated by Rsp5 ubiquitin ligase and functionally redundant PPxY motif proteins.
    Suzuki A, Mochizuki T, Uemura S, Hiraki T, Abe F
    Eukaryotic cell 12(7) 990-997 Jul. 2013
  • Brevundimonas abyssalis sp. nov., a dimorphic prosthecate bacterium isolated from deep-subsea floor sediment.
    Tsubouchi T, Shimane Y, Usui K, Shimamura S, Mori K, Hiraki T, Tame A, Uematsu K, Maruyama T, Hatada Y
    International journal of systematic and evolutionary microbiology 63(Pt 6) 1987-1994 Jun. 2013
  • Polycladomyces abyssicola gen. nov., sp. nov., a thermophilic filamentous bacterium isolated from hemipelagic sediment.
    Tsubouchi T, Shimane Y, Mori K, Usui K, Hiraki T, Tame A, Uematsu K, Maruyama T, Hatada Y
    International journal of systematic and evolutionary microbiology 63(Pt 6) 1972-1981 Jun. 2013
  • Eicosapentaenoic acid plays a role in stabilizing dynamic membrane structure in the deep-sea piezophile Shewanella violacea: a study employing high-pressure time-resolved fluorescence anisotropy measurement.
    Usui K, Hiraki T, Kawamoto J, Kurihara T, Nogi Y, Kato C, Abe F
    Biochimica et biophysica acta 1818(3) 574-583 Mar. 2012
  • New type of pressurized cultivation method providing oxygen for piezotolerant yeast.
    Hiraki T, Sekiguchi T, Kato C, Hatada Y, Maruyama T, Abe F, Konishi M
    Journal of bioscience and bioengineering 113(2) 220-223 Feb. 2012
  • Overexpression of Sna3 stabilizes tryptophan permease Tat2, potentially competing for the WW domain of Rsp5 ubiquitin ligase with its binding protein Bul1.
    Hiraki T, Abe F
    FEBS letters 584(1) 55-60 Jan. 2010
  • Fluconazole modulates membrane rigidity, heterogeneity, and water penetration into the plasma membrane in Saccharomyces cerevisiae.
    Abe F, Usui K, Hiraki T
    Biochemistry 48(36) 8494-8504 Sep. 2009
  • Sorting defects of the tryptophan permease Tat2 in an erg2 yeast mutant.
    Daicho K, Makino N, Hiraki T, Ueno M, Uritani M, Abe F, Ushimaru T
    FEMS microbiology letters 298(2) 218-227 Sep. 2009
  • Mechanistic role of ergosterol in membrane rigidity and cycloheximide resistance in Saccharomyces cerevisiae.
    Abe F, Hiraki T
    Biochimica et biophysica acta 1788(3) 743-752 Mar. 2009
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Papers(paper)close
  • Loop L1 governs the DNA-binding specificity and order for RecA-catalyzed reactions in homologous recombination and DNA repair.
    Shinohara T, Ikawa S, Iwasaki W, Hiraki T, Hikima T, Mikawa T, Arai N, Kamiya N, Shibata T
    Nucleic acids research 43(2) 973-986 Jan. 2015
  • Pressure-induced endocytic degradation of the Saccharomyces cerevisiae low-affinity tryptophan permease Tat1 is mediated by Rsp5 ubiquitin ligase and functionally redundant PPxY motif proteins.
    Suzuki A, Mochizuki T, Uemura S, Hiraki T, Abe F
    Eukaryotic cell 12(7) 990-997 Jul. 2013
  • Brevundimonas abyssalis sp. nov., a dimorphic prosthecate bacterium isolated from deep-subsea floor sediment.
    Tsubouchi T, Shimane Y, Usui K, Shimamura S, Mori K, Hiraki T, Tame A, Uematsu K, Maruyama T, Hatada Y
    International journal of systematic and evolutionary microbiology 63(Pt 6) 1987-1994 Jun. 2013
  • Polycladomyces abyssicola gen. nov., sp. nov., a thermophilic filamentous bacterium isolated from hemipelagic sediment.
    Tsubouchi T, Shimane Y, Mori K, Usui K, Hiraki T, Tame A, Uematsu K, Maruyama T, Hatada Y
    International journal of systematic and evolutionary microbiology 63(Pt 6) 1972-1981 Jun. 2013
  • Eicosapentaenoic acid plays a role in stabilizing dynamic membrane structure in the deep-sea piezophile Shewanella violacea: a study employing high-pressure time-resolved fluorescence anisotropy measurement.
    Usui K, Hiraki T, Kawamoto J, Kurihara T, Nogi Y, Kato C, Abe F
    Biochimica et biophysica acta 1818(3) 574-583 Mar. 2012
  • New type of pressurized cultivation method providing oxygen for piezotolerant yeast.
    Hiraki T, Sekiguchi T, Kato C, Hatada Y, Maruyama T, Abe F, Konishi M
    Journal of bioscience and bioengineering 113(2) 220-223 Feb. 2012
  • Overexpression of Sna3 stabilizes tryptophan permease Tat2, potentially competing for the WW domain of Rsp5 ubiquitin ligase with its binding protein Bul1.
    Hiraki T, Abe F
    FEBS letters 584(1) 55-60 Jan. 2010
  • Fluconazole modulates membrane rigidity, heterogeneity, and water penetration into the plasma membrane in Saccharomyces cerevisiae.
    Abe F, Usui K, Hiraki T
    Biochemistry 48(36) 8494-8504 Sep. 2009
  • Sorting defects of the tryptophan permease Tat2 in an erg2 yeast mutant.
    Daicho K, Makino N, Hiraki T, Ueno M, Uritani M, Abe F, Ushimaru T
    FEMS microbiology letters 298(2) 218-227 Sep. 2009
  • Mechanistic role of ergosterol in membrane rigidity and cycloheximide resistance in Saccharomyces cerevisiae.
    Abe F, Hiraki T
    Biochimica et biophysica acta 1788(3) 743-752 Mar. 2009
  • Crystal structures of the clock protein EA4 from the silkworm Bombyx mori.
    Hiraki T, Shibayama N, Akashi S, Park SY
    Journal of molecular biology 377(3) 630-635 Mar. 2008
  • Crystallization and preliminary crystallographic studies of the metalloglycoprotein esterase A4 using a baculovirus expression system.
    Hiraki T, Shibayama N, Yoon YH, Yun KM, Hamamoto T, Tame JR, Park SY
    Acta crystallographica. Section F, Structural biology and crystallization communications 63(Pt 9) 734-736 Sep. 2007
  • Crystal structures of unliganded and half-liganded human hemoglobin derivatives cross-linked between Lys 82beta1 and Lys 82beta2.
    Park SY, Shibayama N, Hiraki T, Tame JR
    Biochemistry 43(27) 8711-8717 Jul. 2004

Outside Fund Adoption

  • Methane synthesis using the budding yeast expression system
    Ministry of Education, Culture, Sports, Science and Technology:Grants-in-Aid for Scientific Research(挑戦的萌芽研究)
    Project Year :2012 - 2013 Investigator(s) : toshiki HIRAKI
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Outside Fund Adoptionclose
  • Methane synthesis using the budding yeast expression system
    Ministry of Education, Culture, Sports, Science and Technology:Grants-in-Aid for Scientific Research(挑戦的萌芽研究)
    Project Year :2012 - 2013 Investigator(s) : toshiki HIRAKI


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