yanagisawa ken

FacultyDepartmentofBiochemistry,DivisionofStructuralBiochemistry
Job titleProfessorWeb site

Profile

Research Keywords

    ST2L, IL-1 receptor family, contact inhibition

Research Areas

  • Biological science / Molecular biology
  • Basic medicine / General medical chemistry

Research Activities

Papers(other)

  • A Guanosine Diphosphatase Enriched in Golgi Vesicles of Saccharomyces cerevisiae ; Purification and Characterization. (共著)
    Journal of Biological Chemistry 265(31) 1990
  • Murine ST2 gene is a member of the prinary response gene family induced by growth factors.
    YANAGISAWA K, TSUKAMOTO T, TAKAGI T, TOMINAGA S
    FEBS Letter 302(1) 51-53 1992
  • Purification and Properties of GM2 synthase, UDP-N-acetylgalactosamine : GM3 β-N-acetylgalactosaminyltransferase from rat liver
    Biochimica et Biophysica Acta 919 1987
  • The role of nucleotides in the glycoconjugate metabohism ; transport and metabolism of sugar-nucleotides.
    Protein Nucleic Acid Enzyme 37(11) 1992
  • Guanosine Diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae. (共著)
    ABEIJON C, YANAGISAWA K, MANDON E C, HAEUSLER A, MOREMEN K, HIRSCHBERG C B, ROBBINS P W
    Journal of Cell Biology 122(2) 307-323 1993
  • Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type I. (共著)
    YANAGISAWA K, TAKAGI T, TSUKAMOTO T, TETSUKA T, TOMINAGA S
    FEBS Letter 318(1) 83-87 1993
  • Identification of the product of the murine ST2 gene. (共著)
    Biochimica et Biophysica Acta 1178,194-200 1993
  • Different factors bind to the regulatory region of the Na+, K+-ATPase α1-subunit gene during the cell cycle. (共著)
    KAWAKAMI K, YANAGISAWA K, WATANABE Y, TOMINAGA S, NAGANO K
    FEBS Letter 335(2) 251-254 1993
  • The existence of a growth-specific DNA binding factor for the promoter region of mouse ST2 gene.(共著)
    TOMINAGA S, KATO‐YAMAZAKI M, YANAGISAWA K, KAWAKAMI K, TETSUKA T
    FEBS Letter 354(3) 311-314 1994
  • Studies on natural ST2 gene products in the human leukemic cell line UT-7 using monoclonal antihuman ST2 antibodies.(共著)
    Hybridoma 14(5) 419-427 1995
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Papers(other)close
  • A Guanosine Diphosphatase Enriched in Golgi Vesicles of Saccharomyces cerevisiae ; Purification and Characterization. (共著)
    Journal of Biological Chemistry 265(31) 1990
  • Murine ST2 gene is a member of the prinary response gene family induced by growth factors.
    YANAGISAWA K, TSUKAMOTO T, TAKAGI T, TOMINAGA S
    FEBS Letter 302(1) 51-53 1992
  • Purification and Properties of GM2 synthase, UDP-N-acetylgalactosamine : GM3 β-N-acetylgalactosaminyltransferase from rat liver
    Biochimica et Biophysica Acta 919 1987
  • The role of nucleotides in the glycoconjugate metabohism ; transport and metabolism of sugar-nucleotides.
    Protein Nucleic Acid Enzyme 37(11) 1992
  • Guanosine Diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae. (共著)
    ABEIJON C, YANAGISAWA K, MANDON E C, HAEUSLER A, MOREMEN K, HIRSCHBERG C B, ROBBINS P W
    Journal of Cell Biology 122(2) 307-323 1993
  • Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type I. (共著)
    YANAGISAWA K, TAKAGI T, TSUKAMOTO T, TETSUKA T, TOMINAGA S
    FEBS Letter 318(1) 83-87 1993
  • Identification of the product of the murine ST2 gene. (共著)
    Biochimica et Biophysica Acta 1178,194-200 1993
  • Different factors bind to the regulatory region of the Na+, K+-ATPase α1-subunit gene during the cell cycle. (共著)
    KAWAKAMI K, YANAGISAWA K, WATANABE Y, TOMINAGA S, NAGANO K
    FEBS Letter 335(2) 251-254 1993
  • The existence of a growth-specific DNA binding factor for the promoter region of mouse ST2 gene.(共著)
    TOMINAGA S, KATO‐YAMAZAKI M, YANAGISAWA K, KAWAKAMI K, TETSUKA T
    FEBS Letter 354(3) 311-314 1994
  • Studies on natural ST2 gene products in the human leukemic cell line UT-7 using monoclonal antihuman ST2 antibodies.(共著)
    Hybridoma 14(5) 419-427 1995
  • The expression of ST2 gene in helper Tcells and the binding of ST2 protein to myeloma-derived RPMI8226 cells.
    J. Biochemistry(Tokyo) 121(1) 95-103 1997
  • CMP-NeuAC : Galβ1-4 GlcNAc 92-6 Sialyltransferase catalyzes NeuAc transfer to glycolipids.
    Journal of Lipid Research 38(9) 1795-1806 1997
  • Opposite regulations of the expression of cyclin-dependent Kinase inhibitors during contact inhibition. (共著)
    J. Biochem. 125(1) 36-40 1999
  • Different promoter usage and multiple transcription initiation sites of the interkeukin-1 receptor-related human ST2 gene in UT-7 and TM12 cells. (共著)
    IWAHANA H, YANAGISAWA K, ITO‐KOSAKA A, KUROIWA K, TAGO K, KOMATSU N, KATASHIMA R, ITAKURA M, TOMINAGA S
    Eur. J. Biochem. 264(2) 397-406 1999
  • Experimental small bowel transplantation using a newborn intestine in rats : (]G0002[). revasculatization of newborn intestine is independent of vascular endotherial growth factor. (共著)
    UCHIDA H, KOBAYASHI E, YANAGISAWA K, MIZUTA K, KITOH Y, FUJIMURA A, TOMINAGA S, KAWARASAKI H, HASHIZUME K
    J. Pediatr. surg. 34(9) 1396-1400 1999
  • Primary expression of vascular endothelial growth factor geve in growth-stimulated BALB/c-3T3 cells. (共著)
    Jichi Med. School J. 22 87-94 1999
  • Presence and expression of a novel variant form of ST2 geve product in human loubenic cell live UT-7/GM. (共著)
    TOMINAGA S, KUROIWA K, TAGO K, IWAHANA H, YANAGISAWA K, KOMATSU N
    Biochem. Biophys. Res. Commun. 264(1) 14-18 1999
  • Effects of long-term administration of erythromycin on cytobine production in rat alveolar macrophages. (共著)
    Eur. Respir. J. 14 1113-1116 1999
  • Construction of ELISA system to quantify human ST2 protein in sera of patients. (共著)
    KUROIWA K, LI H, TAGO K, IWAHANA H, YANAGISAWA K, KOMATSU N, OSHIKAWA K, SUGIYAMA Y, TOMINAGA S
    Hybridoma 19(2) 151-159 2000
  • The cloning and nucleotide sequence of human ST2L CDNA.
    LI H, TAGO K, IO K, KUROIWA K, ARAI T, IWAHANA H, TOMINAGA S, YANAGISAWA K
    Genomics 67(3) 284-290 2000
  • Elevated soluble ST2 protein levels in sera of asthma patients with an acute exacerbation.
    Am. J. Resp. Crit. Care Med. 164 (2), 277-281 2001
  • Presence of a genistein-responsive inhibitory mechanism on interleukin-1a-induced NF-kB activation.
    TAGO K, FUNAKOSHI M, MANO H, YANAGISAWA K, HAYAKAWA M, KUROIWA K, IWAHANA H, KASAHARA T, TOMINAGA S
    Eur. J. Biochem 268(24) 6526-6533 2001
  • Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V.
    TAGO K, NODA T, HAYAKAWA M, IWAHANA H, YANAGISAWA K, YASHIRO T, TOMINAGA S
    Biochem. Biophys. Res. Commun. 285(5) 1377-1383 2001
  • Expression of ST2 in Helper T Lymphocytes of Malignant Pleural Effusions
    Am. J. Resp. Crit. Care Med. 165 (7), 1005-1009 2002
  • Expression and function of the ST2 gene in a murine model of allergic airway inflammation.
    OSHIKAWA K, YANAGISAWA K, TOMINAGA S, SUGIYAMA Y
    Clin. Exp. Allergy 32(10) 1520-1526 2002
  • ST2 protein induced by inflammatory stimuli can modulate acute lung inflammation.
    OSHIKAWA K, YANAGISAWA K, TOMINAGA S, SUGIYAMA Y
    Biochem. Biophys. Res. Commun. 299(1) 18-24 2002
  • A novel splice variant of mouse interleukin-1 receptor-associated kinase-1 (IRAK-1) activates nuclear factor kB (NF-kB) and c-Jun N-terminal kinase (JNK).
    Biochem. J. in press
  • The effect of ST2 gene product on achorage-independent growth of a glioblastoma cell line, T98G.
    HAGA Y, YANAGISAWA K, OHTO‐OZAKI H, TOMINAGA S, MASUZAWA T, IWAHANA H
    Eur.J.Biochem. 270(1) 163-170 2003

Outside Fund Adoption

  • Biological function of ST2L, an orphan receptor which shows high similarity with IL-1 receptor type I.
  • The role of cyclin despendent Kinase inhibitors in contact inhibition
Display all
Outside Fund Adoptionclose
  • Biological function of ST2L, an orphan receptor which shows high similarity with IL-1 receptor type I.
  • The role of cyclin despendent Kinase inhibitors in contact inhibition


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