Researchers Database

taira koki

    SurgicalCenter Assistant Professor
Last Updated :2021/12/04

Researcher Information

J-Global ID

Research Areas

  • Life sciences / Anesthesiology / PONV
  • Life sciences / Anesthesiology / Post Operative Pain

Academic & Professional Experience

  • 2021/04 - Today  Jichi Medical UniversityAnesthesiology and critical care medicineAssistant professor (Concurrent of operation Department)
  • 2013/01 - 2021/03  Jichi Medical University, School of MedicineDepartment of Anesthesiology and Intensive Care MedicineResearch associate
  • 2012/07 - 2012/12  Okayama University HospitalIntensive Care UnitAdjunct Clinical Associate
  • 2011/04 - 2012/06  Jichi Medical University HospitalDepartment of Anesthesiology and Intensive Care MedicineClinical associate
  • 2006/04 - 2011/03  Jichi Medical University HospitalDepartment of Anesthesiology and Intensive Care MedicineSenior Resident
  • 2004/04 - 2006/03  Jichi Medical University HospitalOffice of Resident EducationJuniour Resident

Association Memberships

  • THE JAPAN SOCIETY FOR PEDIATRIC ANESTHESIA   THE JAPAN SOCIETY FOR REGIONAL ANESTHESIA   THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA   THE JAPANESE SOCIETY OF INTENSIVE CARE MEDICINE   JAPANESE SOCIETY OF ANESTHESIOLOGISTS   日本ペインクリニック学会   

Published Papers

  • Anesthetic management of a patient with 22q11.2 deletion syndrome in scoliosis correction surgery using total intravenous anesthesia with ketamine and propofol
    Koki Taira, Naoyuki Taga, Mamoru Takeuchi
    Clinical pediatric anesthesia 27 (1) 26 - 30 2021/10 [Refereed][Not invited]
  • Miyuki TAKAHASHI, Koki TAIRA,Tetsuhito HARA, Mamoru TAKEUCHI
    The Journal of Japan Society for Clinical Anesthesia 日本臨床麻酔学会 41 (4) 332 - 335 0285-4945 2021/07 [Refereed][Not invited]
  • Koki TAIRA, Kunihisa HOTTA, Mamoru TAKEUCHI
    The Journal of Japan Society for Clinical Anesthesia 41 (3) 223 - 227 0285-4945 2021/05 [Refereed][Not invited]
  • Masaaki Satoh, Koki Taira, Tetsuhito Hara, Juntaro Siba, Mamoru Takeuchi
    Surgical oncology 33 216 - 221 2020/06 [Refereed][Not invited]
     
    OBJECTIVE: High mobility group box 1 (HMGB1) is produced by inflammation. Regarding liver injuries, HMGB1 is reportedly involved in liver regeneration. The present study investigated the use of HMGB1 as a postoperative marker of surgical course in patients with liver cancer. METHODS: Patients were enrolled if they had liver cancer, had undergone liver surgery, and did not develop postsurgical complications. Patients who received emergency surgery or patients with unresectable cancerous lesions were excluded. Blood samples were preoperatively obtained as well as at 1 day, 1 week, and 4 weeks following surgery; white blood cell count, serum C-reactive protein, serum albumin, and serum HMGB1 levels were measured. RESULTS: A total of 36 patients were included in this study. HMGB1 levels significantly changed over time, increasing from a median of 7.1 ng/ml (preoperatively) to 13.9 ng/ml at 1 week postoperatively, and then decreased to 6.3 ng/ml at 4 weeks postoperatively. Peak HMGB1 levels were delayed, and elevated HMGB1 levels persisted as compared with the changes in conventional markers. CONCLUSIONS: HMGB1 indicates a unique perioperative inflammatory state in patients with liver cancer. Serum HMGB1 may serve as a marker for monitoring surgical course in patients undergoing surgery for liver cancer.
  • Risa OKA, JUNTARO SHIBA, Koki TAIRA, Mamoru TAKEUCHI
    Masui. Japanese Journal of Anesthesiology 克誠堂出版(株) 69 (4) 403 - 405 0021-4892 2020/04 [Refereed][Not invited]
     
    症例は72歳男性、血液型はB型であった。転落により胸部を強打し、多発肋骨骨折、血気胸の診断で入院したが、血胸により呼吸状態が悪化したため転院搬送された。胸部造影コンピュータ断層撮影では大量血胸と右肺下葉からの造影剤の血管外漏出を認め、直ちに開胸肺切除および止血術を行ったが、同型の血小板製剤が入手困難であったため、O型血小板輸血製剤を投与したところ、異常低血圧をきたした。異常低血圧はノルアドレナリンに治療抵抗性で、アドレナリン投与を要したことから、異型血小板輸血のアレルギー反応によるものと考えられた。また、手術終了後に気管チューブからピンク色の泡沫痰が多量に吸引され、肺動脈圧高値より前負荷の過剰による非心原性の肺水腫と考えられたが、原因の確定には至らなかった。フロセミドを投与し、術後11日目に抜管となった。
  • Takashi IGARASHI, Nobuhiro SHHHIMADA, Koki TAIRA, Yasunori NIWA, Kunihisa HOTTA, Mamoru TAKEUCHI
    Masui. Japanese Journal of Anesthesiology 克誠堂出版(株) 68 (9) 932 - 939 0021-4892 2019/09 [Not refereed][Invited]
  • [Multimodal approach to postoperative nausea and vomiting: Example after breast cancer surgery]
    Koki TAIRA, Kunihisa HOTTA, Mamoru TAKEUCHI
    J Clin Anesthesia (Jpn) 真興交易(株)医書出版部 43 (8) 1091 - 1097 0387-3668 2019/08 [Invited]
  • [Pediatric Anesthesia Today: Peripheral nerve block in children]
    Kunihisa HOTTA, Koki TAIRA, Mamoru TAKEUCHI
    J Clin Anesthesia (Jpn) 真興交易(株)医書出版部 43 (6) 837 - 843 0387-3668 2019/06 [Invited]
     
    区域麻酔は強力な鎮痛作用を有し、多角的な術後鎮痛戦略において重要な役割を担う。近年、超音波ガイド下に行う末梢神経ブロックは、小児麻酔の領域でも広く行われており、新たな神経筋膜面ブロックの小児への適用も報告されている。小児の末梢神経ブロックは全身麻酔下で行われることが多いが、合併症のリスクは高くならないと考えられている。また、末梢神経ブロックに使用する局所麻酔薬は、患児の体格に応じて安全な用量の範囲内とする。タンパク結合しないフリーの局所麻酔薬の血中濃度が高くなりやすい6ヵ月未満の乳児は、局所麻酔薬中毒のリスクが高く、注意が必要である。(著者抄録)
  • [Pharyngeal hematoma due to post-extraction bleeding and difficulty in securing the airway: a case report]
    Masashi KUNOMURA, Koki TAIRA, Juntaro SHIBA, Tomoyuki SUTO, Mamoru TAKEUCHI
    J Clin Anesthesia (Jpn) 真興交易(株)医書出版部 43 (3) 509 - 510 0387-3668 2019/03 [Refereed][Not invited]
     
    46歳女。右下智歯抜去後の出血が持続し、舌側の浮腫を認めたため、抜歯から5時間後に紹介受診した。来院時には著明な右頬部および軟口蓋の腫脹を認め、口腔内には多量の血性分泌物が貯留しており、呼吸困難感を自覚していた。外来処置室でも止血に至らず、抜歯から6時間半後、麻酔科に全身麻酔下での処置依頼があり、CT検査では血腫による著明な気道の左方偏位を認めた。咽頭血腫による気道狭窄と偏位により気道確保が困難なため、マッキントッシュ喉頭鏡で直視下に血液吸引、凝血塊除去を行うことで視野を確保し、エラスティックブジーを併用したところ、無事、気管挿管し得た。術野所見では抜歯窩近傍の下歯槽神経伴走動静脈の損傷と拍動性出血を認め、電気メスによる焼灼と骨蝋充填により止血を得た。
  • Koki Taira, Soichiro Inoue, Juntaro Shiba, Mamoru Takeuchi
    Masui. The Japanese Jounal of anesthesiology 67 (9) 994 - 998 0021-4892 2018/09 [Refereed][Not invited]
  • Juntaro Shiba, Masaaki Satoh, Koki Taira, Yasunori Niwa, Soichiro Inoue, Koichi Mizuta, Mamoru Takeuchi
    Pediatric Transplantation 22 (1) 1399-3046 2018/02 [Refereed][Not invited]
     
    In patients that have undergone liver transplants, a postoperative reduction in the blood flow of the liver graft represents a critical complication. We recently encountered an interesting phenomenon that is, we found that the rSO2 level of the liver graft, as measured by NIRS, drops in patients that subsequently require an emergency liver biopsy. An 8-month-old female and an 8-month-old male underwent living donor liver transplants for biliary atresia. In both cases, a reduction in rSO2 was detected before an emergency liver biopsy was required. As a result of biopsy examinations, both patients were diagnosed with acute graft rejection. NIRS might be useful for graft management during the postoperative period in pediatric patients that undergo liver transplantation. After a liver transplant, a reduction in the rSO2 of the graft might be indicative of the onset of vascular complications.
  • Kunihisaa HOTTA, Koki TAIRA, Mamoru TAKEUCHI
    The Journal of Japan Society for Clinical Anesthesia 日本臨床麻酔学会 38 (1) 110 - 113 0285-4945 2018/01 [Not refereed][Invited]
  • Hara tetsuhito, Taira koki, Sugimoto kenzaburo, Takeuchi mamoru
    The Journal of Japan Society for Clinical Anesthesia 37 (4) 418 - 422 2017/07 [Refereed][Not invited]
  • Juntaro Shiba, Yasunori Niwa, Koki Taira, Kentaro Hayashi, Soichiro Inoue, Mamoru Takeuchi
    Masui. The Japanese journa] of anesthesiology 克誠堂出版 65 (12) 1245 - 1247 0021-4892 2016/12 [Refereed][Not invited]
  • Yasunori Niwa, Takashi Igarashi, Soichiro Inoue, Koki Taira, Kunihisa Hotta, Mamoru Takeuchi
    Pain clinic 真興交易(株)医書出版部 37 (11) 1431 - 1433 0388-4171 2016/11 [Refereed][Not invited]
     
    微小血管減圧術後に再発した特発性三叉神経痛に対して五苓散が著効した症例を経験した。患者は89歳、女性で、14年前に特発性三叉神経痛に対して微小血管減圧術を受けていた。今回、特発性三叉神経痛が再発し、カルバマゼピン投与を開始したが、副作用のために増量ができなかった。そこで、五苓散7.5g/日を併用したところ、自発痛はほぼ消失した。五苓散は、微小血管減圧術後に再発した特発性三叉神経痛に対して効果を示す可能性が示唆された。(著者抄録)
  • Kunihisa Hotta, Koki Taira, Mamoru Takeuchi
    J Clin Anesthesia (Jpn) 真興交易(株)医書出版部 40 (11) 1517 - 1522 0387-3668 2016/11 [Not refereed][Invited]
  • Kunihisa Hotta, Soichiro Inoue, Koki Taira, Naho Sata, Kenji Tamai, Mamoru Takeuchi
    JOURNAL OF ANESTHESIA 30 (1) 31 - 38 0913-8668 2016/02 [Refereed][Not invited]
     
    Both single-injection transversus abdominis plane (TAP) block and continuous wound infiltration (CWI) provide postoperative analgesia, but no study has compared the two regional techniques. We tested the hypothesis that CWI is more effective for controlling postoperative pain compared with single-injection TAP block after laparotomy. We conducted a prospective randomized study of patients undergoing gynecologic laparotomy with midline incision through the umbilicus under general anesthesia. The patients were allocated to receive either single-injection TAP block (TAP group) or CWI (CWI group) for postoperative analgesia. All patients received intravenous patient-controlled analgesia with morphine and intravenous flurbiprofen twice daily after surgery. Postoperative pain at rest and on coughing, postoperative morphine consumption, incidence of postoperative nausea and vomiting (PONV), pruritus and urinary retention, ambulation, and satisfaction score were recorded. Patients were assessed at 3 h after surgery and twice daily on postoperative days (POD) 1 and 2. Data of 54 patients were analyzed. Compared to the TAP group (n = 27), pain score on coughing was significantly lower in the CWI group (n = 27) on POD1 and POD2 (P < 0.05). Pain score on coughing at 3 h after surgery, pain score at rest at all assessed time points, morphine consumption, incidence of PONV, pruritus and urinary retention, ambulation, and satisfaction score were not different between the two groups. CWI reduced pain on coughing after the day of surgery compared with single-injection TAP block when performed as part of multimodal analgesia in patients undergoing gynecologic laparotomy.
  • Takashi Igarashi, Koki Taira, Nobuhiro Shimada, Kunihiko Murai, Yasunori Niwa, Mamoru Takeuchi
    The Journal of Japanese Society for Clinical Anesthesia 35 (7) 814 - 818 0285-4945 2015/11 [Refereed][Not invited]
  • Yoji Otsuka, Koki Taira, Mamoru Takeuchi
    J Clin Anesthesia (Jpn) 39 (8) 1113 - 1119 0387-3668 2015/08 [Not refereed][Invited]
  • Koki Taira, Soichiro Inoue, Mamoru Takeuchi
    Pediatric Nursing (株)へるす出版 37 (11) 1378 - 1385 0386-6289 2014/10 [Not refereed][Invited]
  • Kunihisa Hotta, Soichiro Inoue, Koki Taira, Naho Sata, Kenji Tamai, Mamoru Takauchi
    The Journal of Japan Society for Clinical Anesthesia 34 (2) 198 - 202 2014/04 [Refereed][Not invited]
  • Koki TAIRA, Mamoru Takeuchi
    resident 6 (12) 79 - 89 2013/12 [Not refereed][Invited]
  • Yoji Ottsuka, Mammoru TAKEUCH, Akiko YAMANAKA, Hidetaka IWAI, Fumihito NAKAMURA, Tatsuya Nagano, Koki TAIRA, Naoyuki TAGA
    体液・代謝管理 29 9 - 13 2013 [Not refereed][Not invited]
  • Naho Sata, Kunihisa Hotta, Koki Taira, Mamoru Takeuchi, Norimasa Seo
    Masui. Japanese Journal of Anesthesiology 克誠堂出版 61 (11) 1281 - 1284 0021-4892 2012/11 [Refereed][Not invited]
     
    We report three cases of continuous wound infiltration (CWI) for postoperative analgesia in upper abdominal surgery using the multi-holed epidural catheter. Ropivacaine 0.2% at a rate of 8 ml·hr-1 was administered through the catheters after surgery. Intravenous-patient controlled analgesia was used as a rescue. The postoperative pain was well controlled, and all patients could walk the next day after surgery. The consumption of rescue morphine was little and no side effect of morphine was observed. CWI is an easy procedure and is indicated in the patients with hemostatic abnormality and a difficulty in the epidural anesthesia. CWI was an effective technique for postoperative pain control in the upper abdominal surgery patients.
  • Kunihisa Hotta, Tetsuya Endo, Koki Taira, Naho Sata, Soichiro Inoue, Mamoru Takeuchi, Norimasa Seo, Shunsuke Endo
    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA 25 (6) 1009 - 1013 1053-0770 2011/12 [Refereed][Not invited]
     
    Design: A prospective, randomized, open study. The regional technique used was not blinded. Setting: A university teaching hospital. Participants: Forty-eight patients undergoing video-assisted thoracoscopic surgery (VATS) for tumor resection. Interventions: Patients received either continuous extrapleural block or continuous epidural block using ropivacaine for a period of 60 hours after surgery. Measurements and Main Results: To evaluate postoperative pain control, the primary and secondary endpoints were the visual analog scale (VAS) on movement and the amount of rescue analgesia, respectively. There were no significant differences between the extrapleural and epidural block groups with regard to VAS at rest and during movement assessed at 4, 12, 24, 36, and 48 hours after surgery, dosage of intravenous morphine (extrapleural: 12.9 +/- 11.3, epidural: 10.2 +/- 6.9 mg), supplemental nonsteroidal anti-inflammatory drugs, incidence of postoperative nausea and vomiting (extrapleural: 12/20, epidural: 11/20), postoperative ambulation (extrapleural: 18 at postoperative day [POD] 1 and 20 at POD 2, epidural: 19 at POD 1 and 20 at POD 2) and hospital stay after surgery (extrapleural: 12.7 +/- 6.3, epidural: 12.6 +/- 4.7 days). Conclusions: Although this study did not show the superiority of continuous extrapleural block relative to continuous epidural in VATS patients, the results suggest that both methods provided effective analgesia with a relatively small dose of rescue morphine. Although the analgesic effects of these techniques were comparable, extrapleural block has the advantage of safety and precise placement of the catheter and can be considered an alternative to epidural block in VATS patients. (C) 2011 Published by Elsevier Inc.
  • INOUE Soichiro, TAIRA Koki, SEO Norimasa
    The Journal of Japan Society for Clinical Anesthesia 30 (4) 683 - 689 0285-4945 2010/07 [Not refereed][Not invited]
  • INOUE Soichiro, TAIRA Koki, SEO Norimasa
    The Journal of Japan Society for Clinical Anesthesia 30 (4) 676 - 682 0285-4945 2010/07 [Not refereed][Not invited]
  • Koki TAIRA, Norimasa SEO
    Pharmacy 61 (5) 2371 - 2373 0044-0035 2010/04 [Not refereed][Invited]
  • Koki Taira, Yoshihiro Hirabayashi, Norimasa Seo
    Masui. The Japanese journal of anesthesiology 克誠堂出版 58 (11) 1465 - 1468 0021-4892 2009/11 [Refereed][Not invited]
  • 平 幸輝, 佐藤 正章, 井上 荘一郎, 平林 由広, 瀬尾 憲正
    蘇生 The Japanese Society of Reanimatology 28 (3) 209a - 209a 0288-4348 2009 
    PDFファイルをご覧下さい。
  • Hirabayashi Y, Otsuka Y, Taira K, Shinohara T, Kikuchi Y, Shimada N, Kono R, Tamai K, Inoue S, Seo N
    Masui. The Japanese journal of anesthesiology 克誠堂出版 57 (8) 1026 - 1030 0021-4892 2008/08 [Refereed][Not invited]
  • HIRABAYASHI YOSHIHIRO, HAKOZAKI TAKAHIRO, FUJISAWA KOJI, HIRUTA MASAHIRO, NIWA YASUNORI, SATA NAHO, SHINOHARA TAKAKO, TAIRA KOKI, TAKAKU YUKO, KAYAMOTO SAKI
    Masui. Japanese Journal of Anesthesiology 56 (8) 962 - 964 0021-4892 2007/08 [Refereed][Not invited]
  • K Takahashi, M Azuma, K Taira, A Baba, Yamamoto, I, SW Schaffer, J Azuma
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 30 (6) 725 - 730 0160-2446 1997/12 [Refereed][Not invited]
     
    The effect of taurine on angiotensin II-induced hypertrophy of cultured neonatal rat heart cells (myocytes and nonmyocytes) was examined. Angiotensin II (1-100 nM) alone caused an increase in the rate of protein synthesis of myocytes without changing the rate of DNA synthesis and cell number. It mediated increases in DNA synthesis and cell number in nonmyocytes. Furthermore, at the lower concentration of 1 nM, it induced c-Sos and c-jun expression in both cultured myocytes and nonmyocytes. Exposure of the cells to taurine (20 mM) in the absence of angiotensin II had no effect on either hyperplastic growth or immediate early response gene expression by the two types of cultured cardiac cells. However, myocytes pretreated for 24 h with 20 mM taurine exhibited reduced responsiveness to angiotensin II(I nM), resulting in lower levels of angiotensin II-mediated stimulation in protein synthesis, and immediate early response gene expression was attenuated. Similarly, taurine treatment of nonmyocytes reduced the degree of hyperplastic growth (DNA synthesis and cell number) and immediate early response gene expression stimulated by angiotensin II. Finally, taurine partially prevented the increase in intracellular free calcium [Ca(2+)](i) mediated by angiotensin II in cardiac cells. Our results indicate that taurine is an effective inhibitor of angiotensin II action.

Books etc

  • 日本麻酔科学会, 日本麻酔科学会・周術期管理チーム委員会 (Joint workERAS)
    日本麻酔科学会 2020/12 9784990526290 xxix, 821p
  • Pallium Palliative Pocketbook 2nd edition
    Jose L.Pereira (Joint translation第5章痛み(5-22~5-42))
    MEDSi 2017/08
  • こうすればうまくいく日帰り手術の麻酔
    大嶽浩司, 井上莊一郎, 村井邦彦, 茂木康一 (Joint work術後悪心・嘔吐)
    中外医学社 2017/06 9784498055308 125-132
  • 抗血栓療法中の区域麻酔・神経ブロック ガイドライン
    日本ペインクリニック学会, 日本麻酔科学会, 日本区域麻酔学会, 合同, 抗血栓療法中の区域麻酔, 神経ブロック ガイドライン, 作成ワーキンググループ (Joint work内臓神経ブロックと抗凝固・抗血栓療法)
    2016/09 153 108-110 
    http://www.regional-anesth.jp/common/pdf/guideline.pdf
  • 日本麻酔学会, 周術期管理チーム委員会 (Joint work86-87)
    日本麻酔科学会 2014/09 4990526228 165
  • 竹内護, 堀田訓久 (Joint work吸入麻酔薬,術前内服薬,運動神経誘発電位,PONV対策)
    中外医学社 2013/05 4498055187 459 39-45,107-110,139-142,415-418
  • 公益社団法人, 日本麻酔科学会, 会員, 日本手術看護学会, 会員, 社団法人, 日本病院薬剤師会, 会員, 社団法人, 日本臨床工学技士会, 会員, 日本麻酔科学会, 周術期管理チームプロジェクト (Joint work輸液管理,輸血療法)
    日本麻酔科学会 2011/05 499052621X 601 354-363
  • 高崎眞弓, 河本昌志, 川真田樹人, 岡本浩嗣, 高崎 眞弓 (Joint work硬膜外腔に筋弛緩薬を後投与したら)
    文光堂 2010/11 4830628324 637 634-635
  • 河原崎 秀雄, 安田 是和, 小林 英司, 河原崎 秀雄 (Joint work術中管理;術前準備,麻酔管理)
    日本医学館 2010/07 4890447075 343 105-114
  • 日本麻酔科学会 (Joint work異形輸血予防)
    日本麻酔科学会 2010/05 9784990526252 xxv, 793p

Conference Activities & Talks

MISC



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