MINOTA seiji

FacultyVicePresident
Job titleVice PresidentWeb site

Profile

Research Keywords

    Rheumatology and Clinical Immunology

Research Areas

  • Clinical internal medicine / General internal medicine (including psychosomatic medicine)

Career

  • 1984
    -
    1988
    University of North Carolina at Chapel Hill,
  • Research assistant
  • 1988
    -
    1993
    University of Tokyo, Research assistant
  • 1993
    -
    1997
    Jichi Medical School, Associate professor
  • 1997
    - Jichi Medical School, Professor

Academic Background

  • -
    1978
    Faculty of Medicine, The University of Tokyo (japan)

Academic Societies

  • American Colledge of Rheumatology
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  • American Colledge of Rheumatology

Research Activities

Papers(other)

  • Rabbit Auti-chroruatin Antibodics Recognize Similar Epitopes on a Histone H-1 Molecule as Lupus Autoautibodies
    Clinical Immunology and Immunologathology 77(1) 52 1995
  • Expression of Transforming Growth Factor-β1 and its Relation to Endomysial Fibrosis in Progrescive Muscular Dystrophy
    American Journal of Pathology 144(2) 221 1994
  • Selective Accumulation of Anti-histone Antibodics in Glomeruli of Lupus-Prone Lpr Mice
    Clinical Immunology and Immunopathology 80(1) 82 1996
  • Regulation of ICAM-1 Exprcesion by Inflammatory Cytokines in Rot Mesangial Cells
    Cytokine 8(2) 109-114 1996
  • Endothelin-1 release from cultured endothelial cells induced by sera from patients with systemic lupus erythematosus
    Annals of the Rheumatic Diseases 54 361 1995
  • Tyrosine phosphorylation of vav prstooncogene product in primary human myelogeuous leukemic cells stimulated by granulocyte colony-stimulating factor
    Biochemical and Biophysical Research Communications 211(2) 677-685 1995
  • Preforin-secreting killer cell infiltration and expression of a 65kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis
    Journal of Clinical Investigation 93(2) 750 1994
  • Antiendothelial cell antibodies and their relation to pulmonary hyperteusion in systemic lugus erythematosus
    Journal of Rheumatology 21 11 1994
  • Autoautibodies to the heat-shock protein hsp90 in systemic lupus erythematosus
    Journal of Clinical Investigation 81(1) 106 1988
  • Autoantibodies to the constitutive 73-kD member of the hsp70 family of heat-shock proteins in systemic lupue erythematosus
    Journal of Experimental Medicine 168(4) 1475-1480 1988
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Papers(other)close
  • Rabbit Auti-chroruatin Antibodics Recognize Similar Epitopes on a Histone H-1 Molecule as Lupus Autoautibodies
    Clinical Immunology and Immunologathology 77(1) 52 1995
  • Expression of Transforming Growth Factor-β1 and its Relation to Endomysial Fibrosis in Progrescive Muscular Dystrophy
    American Journal of Pathology 144(2) 221 1994
  • Selective Accumulation of Anti-histone Antibodics in Glomeruli of Lupus-Prone Lpr Mice
    Clinical Immunology and Immunopathology 80(1) 82 1996
  • Regulation of ICAM-1 Exprcesion by Inflammatory Cytokines in Rot Mesangial Cells
    Cytokine 8(2) 109-114 1996
  • Endothelin-1 release from cultured endothelial cells induced by sera from patients with systemic lupus erythematosus
    Annals of the Rheumatic Diseases 54 361 1995
  • Tyrosine phosphorylation of vav prstooncogene product in primary human myelogeuous leukemic cells stimulated by granulocyte colony-stimulating factor
    Biochemical and Biophysical Research Communications 211(2) 677-685 1995
  • Preforin-secreting killer cell infiltration and expression of a 65kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis
    Journal of Clinical Investigation 93(2) 750 1994
  • Antiendothelial cell antibodies and their relation to pulmonary hyperteusion in systemic lugus erythematosus
    Journal of Rheumatology 21 11 1994
  • Autoautibodies to the heat-shock protein hsp90 in systemic lupus erythematosus
    Journal of Clinical Investigation 81(1) 106 1988
  • Autoantibodies to the constitutive 73-kD member of the hsp70 family of heat-shock proteins in systemic lupue erythematosus
    Journal of Experimental Medicine 168(4) 1475-1480 1988
  • Preferential binding of Escherichia coli hsp60 of antibodies prevalent in sera from patients with rheumatoid arthritis.
    Clin. Immunol. Immunopathol. 82 141 1997
  • Association of Interleukin 6 Release from Endothelial Cells and Pulmonary Hypertension in SLE.
    J. Rheumatol. 24 489 1997
  • Constitutive Tyrosine Phosphorylation of the vav Proto-Oncogene Product in MRL/Mp-lpr/lpr Mice.
    J. Immunol. 158 2977 1997
  • Detection of Large Macrophage Colony Forming Cells in the Peripheral Blood of Patients with Rheumatoid Arthritis.
    J. Rheumatol. 24 1517 1997
  • Correlation of serum IgG antibodies to recombiant human PO fusion protein with IgG antibodies to carboxyl-terminal 22 synthetic peptides and carboxyl-terminal 22 amino acid-deleted recombiant PO fusion protein in patients with systemic lupus erythematosus
    Arthritis Rheum. 40 1364 1997
  • A close temporal relationship of liver disease to antiribosomal PO protein antibodies and cantral nervous system disease in patients with systemic lupus erythematosus
    J. Rheumatol. 25 681 1998
  • Acute acalwlous cholecystitis in systemic lupus erythematosus : a case report and review of literature
    Lupus 7 361 1998
  • Infection with an unenveloped DNA virus(TTV)associated with Non-A to G hepatitis in patients with rheumatoid arthritis
    Br. J. Rheum. 37 1361 1998
  • Characterization of the 4C8 antigen involved in transendothelial migration of CD26hi Tcells after tight adhesion to human umbilical vein endothelial cell monolayers
    J. Exp. Med. 189(6) 979-989 1999
  • Circulating myeloperoxidase and anti-myeloperoxidase antibody in patients with vasculitis
    Scand. J. Rheum. 28 94 1999
  • Invitro and invivo inhibition of activation induced T cell.
    J. Rheum. 27 1358 2000
  • Characterization of chemokine receptor expression and cytokine production in circulatiog CD4 +T cells from patients with atopicdematitis:up-regulation of C-C chemokine receptor 4 in atopic dermatitis.
    Clin. Exp. Allergy 32 1236 2002
  • A novel costimulation pathway via the 4C8 antigen for the induction of CD4 + regulatoty T cells.
    J. Immunol. 169 3710 2002
  • Effects of FTY720 in MRL-lpr/lpr Mice: Therarentic potential in Systemic Lupus Erythematosus
    J. Rheumatol 29, 707-716 2002
  • Von Recklinghausen disease in a patient with X-linked a gammaglobulinemia
    Intern. Med 41, 1039-1043 2002
  • Production of thrimboxane A2 and Prostaglandin I 2 affected by interaction of heat aggregated IgG, endothelial cells, and platelets in lupus nephritis
    J. Rheumatol. 29, 2106-2113 2002
  • Humanized monoclonal anti-interleukin 6-antibody for treatment of intractable adult-onset Still's disease
    Arthritis Rheum. 46, 3388-3389 2002
  • Elevated muscle enzymes in a patient with severe hypocalcemia mimicking polymyositis
    Mod. Rheumatol. 12, 186-189 2002
  • Cogan's syndrome with antineutrophil cytoplasmic autoantibody
    Ann. Rheum. Dis. 61, 761-762 2002

Outside Fund Adoption

  • Mechanism of Autoantibody Formation in Collagen Vaocular Diseases
    Project Year :1984
  • prevention of osteoporosis in rheumatic diseases
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  • Mechanism of Autoantibody Formation in Collagen Vaocular Diseases
    Project Year :1984
  • prevention of osteoporosis in rheumatic diseases

Works

  • Exploration of new therapeutic modalities in rheumatic diseases
    2000
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Worksclose
  • Exploration of new therapeutic modalities in rheumatic diseases
    2000


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