MINOTA seiji

FacultyVicePresident
Job titleVice PresidentWeb site

Profile

Research Keywords

    Rheumatology and Clinical Immunology

Research Areas

  • Clinical internal medicine / General internal medicine (including psychosomatic medicine)

Career

  • 1984
    -
    1988
    University of North Carolina at Chapel Hill,
  • Research assistant
  • 1988
    -
    1993
    University of Tokyo, Research assistant
  • 1993
    -
    1997
    Jichi Medical School, Associate professor
  • 1997
    - Jichi Medical School, Professor

Academic Background

  • -
    1978
    Faculty of Medicine, The University of Tokyo (japan)

Academic Societies

  • American Colledge of Rheumatology
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  • American Colledge of Rheumatology

Research Activities

Papers(other)

  • Rabbit Auti-chroruatin Antibodics Recognize Similar Epitopes on a Histone H-1 Molecule as Lupus Autoautibodies
    Clinical Immunology and Immunologathology 77(1) 52 1995
  • Expression of Transforming Growth Factor-β1 and its Relation to Endomysial Fibrosis in Progrescive Muscular Dystrophy
    American Journal of Pathology 144(2) 221 1994
  • Selective Accumulation of Anti-histone Antibodics in Glomeruli of Lupus-Prone Lpr Mice
    MINOTA S, YOSHIO T, IWAMOTO M, TAKEDA A, MASUYAMA J, MIMORI A, YAMADA A, KANO S
    Clinical Immunology and Immunopathology 80(1) 82-87 1996
  • Regulation of ICAM-1 Exprcesion by Inflammatory Cytokines in Rot Mesangial Cells
    IKEDA M, IKEDA U, SHIMADA K, MINOTA S, KANO S
    Cytokine 8(2) 109-114 1996
  • Endothelin-1 release from cultured endothelial cells induced by sera from patients with systemic lupus erythematosus
    Annals of the Rheumatic Diseases 54 361 1995
  • Tyrosine phosphorylation of vav prstooncogene product in primary human myelogeuous leukemic cells stimulated by granulocyte colony-stimulating factor
    YUO A, KITAGAWA S, IKI S, YAGISAWA M, INUO E K, MIMURA T, MINODA S, URABE A, TAKAKU F
    Biochemical and Biophysical Research Communications 211(2) 677-685 1995
  • Preforin-secreting killer cell infiltration and expression of a 65kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis
    Journal of Clinical Investigation 93(2) 750 1994
  • Antiendothelial cell antibodies and their relation to pulmonary hyperteusion in systemic lugus erythematosus
    Journal of Rheumatology 21 11 1994
  • Autoautibodies to the heat-shock protein hsp90 in systemic lupus erythematosus
    Journal of Clinical Investigation 81(1) 106 1988
  • Autoantibodies to the constitutive 73-kD member of the hsp70 family of heat-shock proteins in systemic lupue erythematosus
    MINOTA S, CAMERON B, WELCH W J, WINFIELD J B
    Journal of Experimental Medicine 168(4) 1475-1480 1988
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Papers(other)close
  • Rabbit Auti-chroruatin Antibodics Recognize Similar Epitopes on a Histone H-1 Molecule as Lupus Autoautibodies
    Clinical Immunology and Immunologathology 77(1) 52 1995
  • Expression of Transforming Growth Factor-β1 and its Relation to Endomysial Fibrosis in Progrescive Muscular Dystrophy
    American Journal of Pathology 144(2) 221 1994
  • Selective Accumulation of Anti-histone Antibodics in Glomeruli of Lupus-Prone Lpr Mice
    MINOTA S, YOSHIO T, IWAMOTO M, TAKEDA A, MASUYAMA J, MIMORI A, YAMADA A, KANO S
    Clinical Immunology and Immunopathology 80(1) 82-87 1996
  • Regulation of ICAM-1 Exprcesion by Inflammatory Cytokines in Rot Mesangial Cells
    IKEDA M, IKEDA U, SHIMADA K, MINOTA S, KANO S
    Cytokine 8(2) 109-114 1996
  • Endothelin-1 release from cultured endothelial cells induced by sera from patients with systemic lupus erythematosus
    Annals of the Rheumatic Diseases 54 361 1995
  • Tyrosine phosphorylation of vav prstooncogene product in primary human myelogeuous leukemic cells stimulated by granulocyte colony-stimulating factor
    YUO A, KITAGAWA S, IKI S, YAGISAWA M, INUO E K, MIMURA T, MINODA S, URABE A, TAKAKU F
    Biochemical and Biophysical Research Communications 211(2) 677-685 1995
  • Preforin-secreting killer cell infiltration and expression of a 65kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis
    Journal of Clinical Investigation 93(2) 750 1994
  • Antiendothelial cell antibodies and their relation to pulmonary hyperteusion in systemic lugus erythematosus
    Journal of Rheumatology 21 11 1994
  • Autoautibodies to the heat-shock protein hsp90 in systemic lupus erythematosus
    Journal of Clinical Investigation 81(1) 106 1988
  • Autoantibodies to the constitutive 73-kD member of the hsp70 family of heat-shock proteins in systemic lupue erythematosus
    MINOTA S, CAMERON B, WELCH W J, WINFIELD J B
    Journal of Experimental Medicine 168(4) 1475-1480 1988
  • Preferential binding of Escherichia coli hsp60 of antibodies prevalent in sera from patients with rheumatoid arthritis.
    HIRATA D, HIRAI I, IWAMOTO M, YOSHIO T, TAKEDA A, MASUYAMA Ji, MIMORI A, KANO S, MINOTA S
    Clin. Immunol. Immunopathol. 82(2) 141-148 1997
  • Association of Interleukin 6 Release from Endothelial Cells and Pulmonary Hypertension in SLE.
    J. Rheumatol. 24 489 1997
  • Constitutive Tyrosine Phosphorylation of the vav Proto-Oncogene Product in MRL/Mp-lpr/lpr Mice.
    J. Immunol. 158 2977 1997
  • Detection of Large Macrophage Colony Forming Cells in the Peripheral Blood of Patients with Rheumatoid Arthritis.
    J. Rheumatol. 24 1517 1997
  • Correlation of serum IgG antibodies to recombiant human PO fusion protein with IgG antibodies to carboxyl-terminal 22 synthetic peptides and carboxyl-terminal 22 amino acid-deleted recombiant PO fusion protein in patients with systemic lupus erythematosus
    Arthritis Rheum. 40 1364 1997
  • A close temporal relationship of liver disease to antiribosomal PO protein antibodies and cantral nervous system disease in patients with systemic lupus erythematosus
    J. Rheumatol. 25 681 1998
  • Acute acalwlous cholecystitis in systemic lupus erythematosus : a case report and review of literature
    KAMIMURA T, MIMORI A, MASUYAMA J, YOSHIO T, OKAZAKI H, KANO S, MINOTA S
    Lupus 7(5) 361-363 1998
  • Infection with an unenveloped DNA virus(TTV)associated with Non-A to G hepatitis in patients with rheumatoid arthritis
    Br. J. Rheum. 37 1361 1998
  • Characterization of the 4C8 antigen involved in transendothelial migration of CD26hi Tcells after tight adhesion to human umbilical vein endothelial cell monolayers
    MASUYAMA J, YOSHIO T, SUZUKI K, KITAGAWA S, IWAMOTO M, HIRATA D, TAKEDA A, KANO S, MINOTA S
    J. Exp. Med. 189(6) 979-989 1999
  • Circulating myeloperoxidase and anti-myeloperoxidase antibody in patients with vasculitis
    Scand. J. Rheum. 28 94 1999
  • Invitro and invivo inhibition of activation induced T cell.
    J. Rheum. 27 1358 2000
  • Characterization of chemokine receptor expression and cytokine production in circulatiog CD4 +T cells from patients with atopicdematitis:up-regulation of C-C chemokine receptor 4 in atopic dermatitis.
    OKAZAKI H, KAKURAI M, HIRATA D, SATO H, KAMIMURA T, ONAI N, MATSUSHIMA K, NAKAGAWA H, KANO S, MINOTA S
    Clin. Exp. Allergy 32(8) 1236-1242 2002
  • A novel costimulation pathway via the 4C8 antigen for the induction of CD4 + regulatoty T cells.
    J. Immunol. 169 3710 2002
  • Effects of FTY720 in MRL-lpr/lpr Mice: Therarentic potential in Systemic Lupus Erythematosus
    J. Rheumatol 29, 707-716 2002
  • Von Recklinghausen disease in a patient with X-linked a gammaglobulinemia
    HIRATA D, NARA H, INABA T, MUROI R, KANEGANE H, MIYAWAKI T, OKAZAKI H, MINOTA S
    Intern. Med 41(11) 1039-1043 2002
  • Production of thrimboxane A2 and Prostaglandin I 2 affected by interaction of heat aggregated IgG, endothelial cells, and platelets in lupus nephritis
    J. Rheumatol. 29, 2106-2113 2002
  • Humanized monoclonal anti-interleukin 6-antibody for treatment of intractable adult-onset Still's disease
    IWAMOTO M, NARA H, HIRATA D, MINOTA S, NISHIMOTO N, YOSHIZAKI K
    Arthritis Rheum. 46(12) 3388-3389 2002
  • Elevated muscle enzymes in a patient with severe hypocalcemia mimicking polymyositis
    Hirata D., Saito S., Nagashima T., Kano S., Okazaki H., Minota S.
    Mod. Rheumatol. 12(2) 186-189 2002
  • Cogan's syndrome with antineutrophil cytoplasmic autoantibody
    IKEDA M, OKAZAKI H, MINOTA S
    Ann. Rheum. Dis. 61(8) 761-762 2002

Outside Fund Adoption

  • Mechanism of Autoantibody Formation in Collagen Vaocular Diseases
    Project Year :1984
  • prevention of osteoporosis in rheumatic diseases
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  • Mechanism of Autoantibody Formation in Collagen Vaocular Diseases
    Project Year :1984
  • prevention of osteoporosis in rheumatic diseases

Works

  • Exploration of new therapeutic modalities in rheumatic diseases
    2000
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  • Exploration of new therapeutic modalities in rheumatic diseases
    2000


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