Researchers Database

kawahito kouji

    SurgeryCardiovascularSurgery Professor
Last Updated :2021/11/23

Researcher Information

Degree

  • (BLANK)

URL

J-Global ID

Research Interests

  • PCPS   体外循環   リンパ球   アポトーシス   心臓手術   

Research Areas

  • Life sciences / Cardiovascular surgery
  • Life sciences / Respiratory surgery
  • Life sciences / Cardiovascular surgery

Academic & Professional Experience

  • 2014  Jichi Medical UniversitySchool of Medicine教授

Education

  •        - 1986  The University of Tokushima  Faculty of Medicine  School of Medicine
  •        - 1986  The University of Tokushima  Faculty of Medicine

Association Memberships

  • The International Society for Rotary Blood Pumps   日本人工臓器学会   日本心臓血管外科学会   日本胸部外科学会   日本外科学会   

MISC

  • 木村 直行, 伊藤 智, 田中 正史, 川人 宏次, 田村 敦, 木村 知恵里, 森田 英幹, 由利 康一, 松本 晴信, 安達 晃一, 山口 敦司, 安達 秀雄  日本外科学会雑誌  114-  (2)  2013/03  [Not refereed][Not invited]
  • 齊藤 力, 三澤 吉雄, 河田 政明, 小西 宏明, 川人 宏次, 大木 伸一, 上西 祐一朗, 坂野 康人, 相澤 啓, 村岡 新, 佐藤 弘隆, 高澤 一平, 棚澤 壮樹, 宮原 義典  日本外科学会雑誌  114-  (2)  2013/03  [Not refereed][Not invited]
  • 木村 直行, 田中 正史, 安達 秀雄, 川人 宏次, 山口 敦司, 井野 隆史  日本外科学会雑誌  109-  (2)  2008/04  [Not refereed][Not invited]
  • 川人 宏次, 安達 秀雄, 井野 隆史  日本外科学会雑誌  108-  (2)  2007/03  [Not refereed][Not invited]
  • Hiromu Inoue, Takanori Yasu, Koji Kawahito, Norifumi Kubo, Junji Nishida, Masanobu Kawakami, Muneyasu Saito  Journal of Cardiology  48-  (3)  159  -163  2006  [Not refereed][Not invited]
     
    A 40-year-old man presented with massive pulmonary embolism related to diffuse large B cell lymphóma. His hemodynamic state worsened rapidly to shock after sudden onset of dyspnea. Echocardiography and thoracic computed tomography indicated pulmonary thromboembolism due to deep venous thromboembolism, associated with a mass in the anterior mediastinum and a 5 × 8cm mass in the left pelvis compressing the left femoral vein. He underwent emergent surgery to remove a huge thrombus from the right atrium through the bilateral pulmonary arteries. Soon after this surgery, his hemodynamic state recovered and excision of the left cervical lymph node revealed diffuse large B cell lymphoma. Venous compression by the lymphoma mass had caused hemostasis and thrombus formation in the present case.
  • MISHIMA Toshiaki, KAWAHITO Koji, MURATA Sei-ichiro, ADACHI Hideo, INO Takashi  日本血管外科学会雑誌 = The Japanese journal of vascular surgery : official journal of the Japanese Society for Vascular Surgery  14-  (6)  639  -644  2005/10  [Not refereed][Not invited]
  • ITO Satoshi, KIMURA Naoyuki, KAWAHITO Koji, ADACHI Hideo, INO Takashi  日本血管外科学会雑誌 = The Japanese journal of vascular surgery : official journal of the Japanese Society for Vascular Surgery  14-  (4)  563  -567  2005/06  [Not refereed][Not invited]
  • Ito Satoshi, Kawahito Koji, Tanaka Masashi, Noguchi Kenichiro, Yamaguchi Atushi, Murata Seiichiro, Adachi Koichi, Adachi Hideo, Ino Takashi  Japanese Journal of Cardiovascular Surgery  34-  (3)  167  -171  2005/05  [Not refereed][Not invited]
     
    We reviewed our experience with 19 mm size aortic valve prostheses for cases with small aortic annulus. Forty-six patients operated on between 1990 and Septembr 2002 were enrolled in this study. Clinical late assessment was performed to evaluate the incidence of valverelated complications, residual transprosthetic gradient, left ventricular mass index (LVMI), and NYHA functional class. Postoperative echocardiography was performed to evaluate hemodynamic performance of the prostheses. Follow up was 1 to 12.7 years (mean 5.3±3.6). There was no hospital mortality (0%). Actuarial survival rates at 10 years were 81.4±1.5%. The late postoperative peak gradient was 25±11 mmHg. LVMI was significantly reduced in late phase. NYHA functional class significantly improved in the late period. Although 19 mm size aortic valve prosthesis remains small transprosthetic pressure gradient, LVMI significantly reduced and patient activity was satisfactory maintained in the late period.
  • MURATA S, KAWAHITO K, YAMAGUCHI A, ADACHI H, INO T  日本冠疾患学会雑誌 = Journal of the Japanese Coronary Association  10-  (2)  85  -88  2004/06  [Not refereed][Not invited]
  • YAMAGUCHI Atsushi, NOGUCHI Ken-ichiro, ADACHI Hideo, KAWAHITO Koji, MURATA Sei-ichiro, INO Takashi  日本心臓血管外科学会雑誌  33-  (2)  73  -76  2004/03  [Not refereed][Not invited]
  • 川人 宏次, 安達 秀雄, 山口 敦司, 村田 聖一郎, 井野 隆史  日本外科学会雑誌  105-  (0)  2004/03  [Not refereed][Not invited]
  • 安達 秀雄, 井野 隆史, 川人 宏次, 村田 聖一郎, 安達 晃一  日本外科学会雑誌  105-  (0)  2004/03  [Not refereed][Not invited]
  • 山口 敦司, 遠藤 英仁, 川人 宏次, 安達 秀雄, 井野 隆史  日本外科学会雑誌  104-  (0)  178  -179  2003/04  [Not refereed][Not invited]
  • FUJIMOTO Koichi, ADACHI Hideo, KAWAHITO Koji, YAMAGUCHI Atsushi, INO Takashi  日本血管外科学会雑誌 = The Japanese journal of vascular surgery : official journal of the Japanese Society for Vascular Surgery  11-  (6)  645  -648  2002/10  [Not refereed][Not invited]
  • SUZUKI Shintaro, TOYAMA Nobuyuki, KAWAHITO Koji, SUMINAGA Yoshihisa, KONISHI Fumio  日本臨床外科学会雑誌 = The journal of the Japan Surgical Association  63-  (6)  1534  -1536  2002/06  [Not refereed][Not invited]
  • YAMAGUCHI A, ADACHI H, KAWAHITO K, ADACHI K, INO T  日本冠疾患学会雑誌 = Journal of the Japanese Coronary Association  8-  (2)  54  -57  2002/06  [Not refereed][Not invited]
  • 川人 宏次, 安達 秀雄, 山口 敦司, 井野 隆史  日本外科学会雑誌  103-  (0)  2002/03  [Not refereed][Not invited]
  • 川人 宏次, 安達 秀雄, 山口 敦司, 井野 隆史  日本外科学会雑誌  103-  (0)  2002/03  [Not refereed][Not invited]
  • 川人 宏次, 山口 敦司, 坪井 潤一, 由利 康一, 桜川 浩, 藤本 耕一, 田中 正史, 遠藤 英仁, 安達 秀雄, 井野 隆史  日本外科学会雑誌  102-  (0)  2001/03  [Not refereed][Not invited]
  • 田中 正史, 川人 宏次, 安達 秀雄, 山口 敦司, 坪井 潤一, 由利 康一, 桜川 浩, 藤本 耕一, 遠藤 英仁, 井野 隆史  日本外科学会雑誌  102-  (0)  2001/03  [Not refereed][Not invited]
  • ADACHI H, KAWAHITO K, YAMAGUCHI A, MURATA S, HARIYA A, ANDO T, YURI K, TSUBOI J, INO T  脈管学  40-  (6)  311  -315  2000/06  [Not refereed][Not invited]
  • 川人 宏次, 安達 秀雄, 井野 隆史  日本外科学会雑誌  101-  (0)  2000/03  [Not refereed][Not invited]
  • ADACHI H, SATO M, MURATA S, OKADA M, HARIYA A, TSUBOI J, KAWAHITO K, INO T  脈管学 : 日本脈管学会機関誌 : the journal of Japanese College of Angiology  39-  (8)  411  -414  1999/08  [Not refereed][Not invited]
  • 川人 宏次, 三澤 吉雄, 布施 勝生  日本外科学会雑誌  100-  (0)  1999/02  [Not refereed][Not invited]
  • 村田 聖一郎, 川人 宏次, 井野 隆史, 安達 秀雄, 針谷 明房, 佐藤 政弥, 岡田 昌彦, 坪井 潤一  日本外科学会雑誌  100-  (0)  1999/02  [Not refereed][Not invited]
  • 安達 秀雄, 村田 聖一郎, 岡田 昌彦, 坪井 潤一, 針谷 明房, 佐藤 政弥, 川人 宏次, 井野 隆史  日本外科学会雑誌  100-  (0)  1999/02  [Not refereed][Not invited]
  • 三澤 吉雄, 布施 勝生, 川人 宏次  日本外科学会雑誌  100-  (0)  1999/02  [Not refereed][Not invited]
  • K Kawahito, E Kobayashi, H Iwasa, Y Misawa, K Fuse  ANNALS OF THORACIC SURGERY  67-  (1)  79  -84  1999/01  [Not refereed][Not invited]
     
    Background. In regard to postoperative bleeding, the most important consequence of cardiopulmonary bypass (CPB) is the loss of aggregability. However, the mechanism of platelet aggregation loss during CPB is unclear. Newly developed particle-counting methods that use light scattering can be used to quantify changes in the number of platelet aggregates of different sizes after application of an aggregating stimulus. Using a lightscattering method, we investigated changes in platelet aggregation during cardiac operation. Methods. Nineteen patients undergoing CPB were evaluated. Blood samples were obtained before the operation, 1 hour after initiation of CPB, at the end of CPB, at the end of the operation, and on day 1 after the operation. Platelet aggregation after stimulation by 2.5 mu mol/L adenosine diphosphate and 2.0 mu g/mL collagen was determined; small (9 to 25 mu m), medium (25 to 50 mu m), and large (50 to 70 mu m) aggregates were counted. Results. Generation of medium and large aggregates after stimulation with adenosine diphosphate and collagen were significantly decreased with CPB, whereas, in spite of hemodilution, the quantity of the small aggregates was maintained at the elevated level. Conclusions. These results reflect the fact that CPB does not affect the first phase of aggregation. It suggests that platelet dysfunction associated with CPB is mainly caused by an inhibition in the development of small aggregates into larger aggregates. (C) 1999 by The Society of Thoracic Surgeons.
  • SAITO Tsutomu, KAWAHITO Koji, HASEGAWA Nobuyuki, MISAWA Yoshio, KATO Morito, FUSE Katsuo  日本心臓血管外科学会雑誌  27-  (6)  360  -363  1998/11  [Not refereed][Not invited]
  • MISAWA Y, FUSE K, KAWAHITO K, KONISHI H  Jinko Zoki  27-  (2)  578  -581  1998/04  [Not refereed][Not invited]
     
    CAPIOX EBS is a newly developed heparin-coated system for percutaneous cardiopulmonary support. Ten patients were assisted by this system after cardiac surgery because of low cardiac output syndrome in our institute, and 18 kits of CAPIOX EBS were installed in these patients. Non of the 18 kits showed any troublesome within 24 h of circulatory assist, but 6 kits were replaced over 36 h of circulatory assist because of hemolysis, annoying noise from the pump, or impaired oxygenation. Out of these 6 kits, two pumps revealed blood clot formation at the outlet and another two oxygenators showed plasma leakage. The mean running period of the other twelve kits was 142h (2-194h), and they did not show any functional waning. We needed 5 to 10 min for kit exchange, and hemodynamic deterioration during the procedure was minimal, and all patients requiring a new kit regained stable hemodynamic state immediately after kit exchange.
  • 三澤 吉雄, 布施 勝生, 小西 宏明, 加藤 盛人, 上沢 修, 齋藤 力, 川人 宏次, 登坂 直規, 齋藤 紀子, 大谷 真一, 福田 稔  日本外科学会雑誌  99-  (0)  1998/03  [Not refereed][Not invited]
  • 川人 宏次, 小林 英司, 原田 和博, 大森 正規, 鬼頭 康彦, 三澤 吉雄, 藤村 昭夫, 布施 勝生  日本外科学会雑誌  99-  (0)  1998/03  [Not refereed][Not invited]
  • Surg today  28-  (9)  971  -973  1998  [Not refereed][Not invited]
  • Artif Organs  22-  348  -52  1998  [Not refereed][Not invited]
  • Arch Surg  133-  216  -7  1998  [Not refereed][Not invited]
  • Extracorporeal membrane oxygenation support and cytokines
    Ann Thorac Surg  65-  1192  -3  1998  [Not refereed][Not invited]
  • トピックス-経皮的心肺補助装置(PCPS)
    メジカルビュー  32  1998  [Not refereed][Not invited]
  • Ann Thorac Surg  66-  982  -3  1998  [Not refereed][Not invited]
  • HASEGAWA Nobuyuki, FUSE Katsuo, KAMISAWA Osamu, KATO Morito, MISAWA Yoshio, KAWAHITO Koji  日本血管外科学会雑誌 = The Japanese journal of vascular surgery : official journal of the Japanese Society for Vascular Surgery  6-  (6)  763  -767  1997/10  [Not refereed][Not invited]
  • KAWASHIMA Takahisa, KAMISAWA Osamu, OHKI Shinichi, HASEGAWA Nobuyuki, KONISHI Hiroaki, KAWAHITO Koji, TOSAKA Naoki, MISAWA Yoshio, KATO Morito, FUSE Katsuo  日本心臓血管外科学会雑誌  26-  (5)  318  -321  1997/09  [Not refereed][Not invited]
  • KAWAHITO K, BENKOWSKI Robert, OTSUBO S, FUSE K, NOSE Y, DEBAKEY Michael E  Jinko Zoki  26-  (3)  806  -810  1997/06  [Not refereed][Not invited]
     
    We introduce the computer technology to enable an accurate, efficient, and reliable design process of an implantable axial flow VAD. The device design is computer-modeled with a parametric solid modeler. To eliminate the high negative pressure area, we performed computational fluid stress analysis on pump design. To improve efficiency and anti-thrombogenicity, CFD (computational fluid dynamics) study is performed to determine pressure and velocity of the fluid in the pump and eliminate the stagnant areas. Machining paths for prototype fabrication are generated using CAM software. And they are machined using CNC (computer numerically controlled) milling machine. Hemolytic characteristics was dramatically improved to 0.002g/100L of normalized index of hemolysis. Total system efficiency was improved to 14%. And Ex vivo 2 week implantation demonstrated excellent anti-thrombogenicity. The use of the CAD/CAM/CAE made it possible to develop a VAD rapidly and successfully.
  • KAWASHIMA Takahisa, KAMISAWA Osamu, OHKI Shinichi, HASEGAWA Nobuyuki, KAWAHITO Koji, FUSE Katsuo  日本血管外科学会雑誌 = The Japanese journal of vascular surgery : official journal of the Japanese Society for Vascular Surgery  6-  (1)  71  -74  1997/02  [Not refereed][Not invited]
  • Hemolysis in different centrifugal pumps
    Artif Organs  21-  323  -6  1997  [Not refereed][Not invited]
  • Platelet damage caused by the centrifugal pump : in vitro evaluation by measuring the release of α-granule packing proteins
    Artif Organs  21-  1105  -9  1997  [Not refereed][Not invited]
  • Improved flow straightener reduce thrombus in the NASA/DeBakey axial flow ventricular assist device
    Artif Organs  21-  339  -43  1997  [Not refereed][Not invited]
  • Ex vivo evaluation of the NASA/DeBakey axial flow ventricular assist device. Results of a 2 week screening test
    ASAIO J  42-  M754-7  1996  [Not refereed][Not invited]
  • Surgery Today(Jpn J Surg)  26-  (8)  652  -654  1996  [Not refereed][Not invited]
  • K Kawahito, G Damm, R Benkowski, G Aber, J Bacak, K Tasai, T Shimono, S Takatani, Y Nose, GP Noon, ME DeBakey  ARTIFICIAL ORGANS  20-  (1)  47  -52  1996/01  [Not refereed][Not invited]
     
    A small ventricular assist device intended for long-term implantation has been developed by a cooperative effort between the Baylor College of Medicine and the NASA/Johnson Space Center. To date, in vitro tests have been performed to address hemolysis and pump performance issues. In this Phase 1 study, we assessed the durability and atraumatic features aiming for 2 day implantation. Eight pumps were implanted in 2 calves as paracorporeal left ventricular assist devices. The pump running times ranged from 18 to 203 h (78.1 +/- 23.7; mean +/- SEM). All the pump implantations were terminated because of thrombus formation. Plasma-free hemoglobin levels were below 13.7 mg/dl, except for 1 case complicated by inflow cannula obstruction. The pump speed was maintained between 10,100 and 11,400 rpm. Pump outputs were from 3.6 to 5.2 L/min. The electrical power required by the system ranged between 9 and 12 W. Clinically there was no detectable organ dysfunction noted, and postmortem evaluation demonstrated no pump related adverse effects in either calf except for small kidney infarctions. Thrombus deposition was observed mainly at the hub portions and the now straightener.
  • Phase 1 ex vivo studies of the Baylor/NASA axial flow ventricular assist device
    Artficial Heart5, Springer-Verlag Tokyo  245  -252  1996  [Not refereed][Not invited]
  • 川人 宏次  血管  18-  (3)  99  -106  1995/08  [Not refereed][Not invited]
  • K KAWAHITO, K TASAI, S MURATA, A YAMAGUCHI, A MIZUHARA, H ADACHI, T INO  ARTIFICIAL ORGANS  19-  (8)  857  -863  1995/08  [Not refereed][Not invited]
     
    A new antithrombogenic material was studied, fluorine-acryl-styrene-urethane-silicone (FASUS) copolymer, the theoretical basis of which attributed to its hydrophilic and hydrophobic microdomain structure. In this series of experiments, the blood compatibility of this copolymer was evaluated in vitro and ex vivo. For the in vitro evaluation, a whole blood clotting test and the microsphere column test were performed. For the ex vivo evaluation, two series of shunt tests in rabbits were performed, one was the arterioartery (A-A) shunt model, and the other was the arteriovenous (A-V) shunt model. The antithrombogenicity was assessed by measuring the shunt obstructive time in the A-A shunt experiment. The A-V shunt experiment was assessed by measuring the circulating platelet counts, platelet aggregability, activated partial thromboplastin time (APTT), and prothrombin time (PT). In the whole blood clotting test, FASUS revealed the significantly longer blood clotting time than that of the control glass tubings (19.7 +/- 1.0 versus 6.5 +/- 0.7 min, p < 0.001). In the microsphere column test, the coated group had a 30% reduction of the platelet number in the eluted blood in contrast with a marked decrease of 70% in the control group (p < 0.05). In the ex vivo A-A shunt experiment, the occlusion time for the FASUS-coated group was significantly longer than that of the control (109.7 +/- 17.3 versus 3.0 +/- 0.4 min, p < 0.05). The A-V shunt experiment showed that the FASUS copolymer suppressed the decrease in platelet counts and tended to improve prolonged APTT compared with that of the control. Clinically, in 25 patients, we placed coated FASUS copolymer into the cannulas for use in percutaneous cardiopulmonary support (PCPS) procedures. There was no evidence of thrombus on the blood contacting surface and no thromboembolism in major organs clinically or upon postmortem examination. In summary, this new copolymer may be effective in preventing thrombus formation in vitro, ex vivo, and in clinical situations.
  • K KAWAHITO, M KAWAKAMI, T FUJIWARA, H ADACHI, T INO  JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY  110-  (1)  99  -102  1995/07  [Not refereed][Not invited]
     
    Cardiac operations with cardiopulmonary bypass cause a systemic inflammatory response. Neutrophils and monocytes-macrophages play an important role in triggering the initiation of the inflammatory response. Recently, some kinds of cytokines that are powerful leukocyte chemotactic factors have been characterized concerning an inflammatory response: interleukin-8 has a potent chemoattractant activity for neutrophils, and monocyte chemoattractant factor has monocyte-macrophage chemotactic activity, To investigate the possible roles of the cytokines in the inflammatory response in cardiopulmonary bypass, 12 adult patients undergoing cardiopulmonary bypass were studied for measurement of interleukin-8 and monocyte chemoattractant factor, Systemic blood was collected before cardiopulmonary bypass, at the end of cardiopulmonary bypass, and at 3, 12, 24, and 48 hours after cardiopulmonary bypass from the patients' radial arteries, Significant increases in levels of interleukin-8 and monocyte chemoattractant factor were detected with a peak level at 3 hours after bypass compared with levels before cardiopulmonary bypass (p < 0.05). This study demonstrated that interleukin-8 and monocyte chemoattractant factor are released into the circulation after adult hypothermic cardiopulmonary bypass and reach a maximum level 3 hours after bypass.
  • 小林 信彦, 久保 典史, 藤井 幹久, 勝木 孝明, 大村 延博, 斉藤 宗靖, 山口 敦司, 川人 宏次, 井野 隆史  Japanese circulation journal  59-  (0)  1995/06  [Not refereed][Not invited]
  • ADACHI Hideo, MURATA Seiichiro, MIZUHARA Akihiro, YAMAGUCHI Atsushi, KAMIO Hitoshi, KAWAHITO Koji, INO Takashi  Jinko Zoki  24-  (3)  878  -881  1995/06  [Not refereed][Not invited]
     
    Open proximal anastomosis with hypothermic circulatory arrest was used for the replacement of descending aorta in 7 patients. Left heart bypass and partial cardiopulmonary bypass with anti-thrombotic system were also used in 7 and 6 patients, respectively. These three systems were compared with each other in terms of the results of treatment and clinical usefulness. One patient with left heart bypass and two patients with partial cardiopulmonary bypass died due to the thrombosis by the aortic clamp and the aortic dissection by the trouble of anastomosis. One patient with open anastomosis died due to LOS despite of uneventful anastomosis. Open proximal anastomosis may be useful for the patient with the aortic pathology extended to the distal aortic arch. The patient with aortic dissection in the descending aorta may be also a good candidate for this method.
  • K KAWAHITO, H ADACHI, T INO, H IDE, A MIZUHARA, A YAMAGUCHI  VASCULAR SURGERY  29-  (2)  153  -157  1995/03  [Not refereed][Not invited]
     
    A forty-four-year-old woman presented with a DeBakey-type IIIb dissecting aneurysm, multiple aneurysmal dilatation of the coronary arteries, and a ''string-of-beads'' appearance of the peripheral arteries (due to cystic medial necrosis and intimal hyperplasia). Upon assessment of her family history and multiple vascular involvement secondary to cystic medial necrosis, an incomplete Marfan's syndrome was suggested. This rare case of multiple aneurysmal changes to the great and peripheral arteries is presented with special reference to the radiographic and morphologic manifestations.
  • Proinflammatory cytokine levels in patients undergoing cardiopulmonary bypass. Does lung reperfusion influence the release of cytokines?
    ASAIO J  41-  M775-778  1995  [Not refereed][Not invited]
  • K. Kawahito, T. Ino, H. Adachi, H. Ide, A. Mizuhara, A. Yamaguchi  ASAIO Journal  40-  (4)  972  -976  1994/10  [Not refereed][Not invited]
     
    To overcome the hemorrhagic complications that may occur during extracorporeal circulatory support for post cardiotomy shock patients, a heparinized circuit was introduced into the percutaneous cardiopulmonary support system and decreased systemically administered heparin during bypass. Heparin coated percutaneous cardiopulmonary support with low dose systemic heparinization was instituted in 13 patients (6 men and 7 women, mean age 62.2 ± 8.5 years) who experienced circulatory collapse after cardiac surgery. Of the 13 patients, 9 could not be weaned from cardiopulmonary bypass and 4 had circulatory collapse in the operating room or in the intensive care unit. The duration of support ranged from 1 to 66 hr (mean 27.4 ± 26.7), and the flow rate ranged from 1 to 3 L/min (2.2 ± 0.5). An activated coagulation time of about 150 sec was maintained with or without minimal systematically administered heparin. Of the patients cannulated, 77% (10 of 13) were successfully weaned from percutaneous cardiopulmonary support and 39% (5 to 13) were long-term survivors. The causes of death were sepsis in three, progressive heart failure in three, lower leg ischemia in one, and vital infection in one. From the results of clinical or post mortem examinations, there was no massive bleeding or evidence of thromboembolism in the major organs. From observations made within 12 hr of initiation of percutaneous cardiopulmonary support, there was no significant decrease in the number of platelets, but platelet count had significantly decreased 24 hr after initiation. The authors' experience indicates that heparin coated percutaneous cardiopulmonary support with low dose systemic heparinization is beneficial for circulatory assist in circulatory collapse after cardiac surgery because of its simplicity and antithrombogenicity, which thus avoids the risk of bleeding complications.
  • 体外循環回路の抗血栓性材料の開発
    3-  192  -193  1994  [Not refereed][Not invited]
  • 原発性右房血管肉腫の1例
    日本胸部外科学会雑誌  42-  1069  -1072  1994  [Not refereed][Not invited]
  • Inferior vena caval tumor thrombus from renal angiomyolipoma-a case report
    Vascular Surgery  28-  213  -218  1994  [Not refereed][Not invited]
  • 川人 宏次, 井手 博文, 井野 隆史, 安達 秀雄, 水原 章浩, 山口 敦司  日本心臓血管外科学会雑誌  23-  (1)  15  -20  1994  [Not refereed][Not invited]
  • 川人 宏次, 井野 隆史, 安達 秀雄, 井手 博文, 水原 章浩, 山口 敦司, 村田 聖一郎  人工臓器  23-  (3)  612  -617  1994  [Not refereed][Not invited]
  • 来院時心肺停止症例に対するPCPS(Percutaneous Cadiopulmonary Support)を用いた蘇生術
    日本胸部外科学会雑誌  42-  121  -125  1994  [Not refereed][Not invited]
  • 川人 宏次, 井野 隆史, 安達 秀雄, 井手 博文, 水原 章浩, 山口 敦司, 村田 聖一郎  人工臓器  23-  (3)  712  -716  1994  [Not refereed][Not invited]
  • 川人 宏次, 井野 隆史, 安達 秀雄, 井手 博文, 水原 章浩, 山口 敦司, 村田 聖一郎  人工臓  23-  (1)  102  -106  1994  [Not refereed][Not invited]
  • A new antithrombogenic coating material"Fluorine-acryl-styrene-urethane-silicone graft-block copolymer" for a circulatory assist device. Heart Replacement.
    Artificial Heart4 Springer-Verlag  37  -40  1993  [Not refereed][Not invited]
  • 新しい抗血栓性材料を用いた抗血栓性経皮的補助循環システムの開発
    日本胸部外科学会雑誌  41-  1467  -1477  1993  [Not refereed][Not invited]
  • Aberrant right subclavian artery aneurysmの1手術例
    41-  148  -152  1993  [Not refereed][Not invited]
  • 緊急 大動脈弁置換術直後に僧帽弁逆流の改善が経食道ドップラエコーで確認された大動脈弁狭窄症の1例
    日本画像医学会雑誌  13-  253  -258  1992  [Not refereed][Not invited]
  • 日本臨床外科医学会雑誌  53-  2948  -2952  1992  [Not refereed][Not invited]
  • 新しい抗血栓性材料を用いたV-Aバイパスからの1離脱例
    日本胸部外科学会雑誌  40-  1110  -1115  1992  [Not refereed][Not invited]
  • 胆道再建術式としての肝管十二指腸吻合術の検討
    外科  53-  735  -738  1991  [Not refereed][Not invited]
  • Mycobacterium fortuitumによる開心術後縦隔炎の4治験例
    日本胸部臨床  50-  508  -512  1991  [Not refereed][Not invited]
  • 日本消化器外科学会雑誌  24-  2457  -2460  1991  [Not refereed][Not invited]
  • 血清中および嚢胞内CA19-9,SLXが高値を示した胸腺嚢腫の1手術例
    日本胸部臨床  49-  841  -845  1990  [Not refereed][Not invited]
  • Bullaの経過観察中に嚢胞壁に発生した肺癌の1切除例
    外科  52-  527  -530  1990  [Not refereed][Not invited]
  • 外傷性三尖弁閉鎖不全症の1治験例
    胸部外科  42-  1047  -1049  1989  [Not refereed][Not invited]

Awards & Honors

  • 1995 Innovative Research Award The International Society for Rotary Blood pumps

Research Grants & Projects

  • Study on Mechanical Circulatory Support
  • 機械的補助循環に関する研究


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