takahashi masaharu

FacultyInfectionandImmunityVirology
Job titleAssistant ProfessorWeb site

Profile

Research Keywords

    Viral Hepatitis

Research Areas

  • Basic medicine / Virology
  • Basic medicine / Immunology

Career

  • Jichi Medical University, Lecturer
  • 1985
    -
    1999
    Researcher, Institute of Immunology, Co, Ltd
  • 2000
    -
    2003
    Reseach Associate, Jichi Medical School
  • 2003
    - Lecturer, Jichi Medical School

Academic Background

  • -
    1985
    Graduate School, Division of Agriculture, Iwate University (japan)
  • -
    1983
    Faculty of Agriculture, Iwate University (japan)

Research Activities

Papers(paper)

  • Frequent detection and characterization of hepatitis E virus variants in wild rats (Rattus rattus) in Indonesia
    Mulyanto, Depamede SN, Sriasih M, Takahashi M, Nagashima S, Jirintai S, Nishizawa T, Okamoto H
    Arch Virol 158(1) 87-96 2012
  • Molucular analysis of hepatitis E virus from farm rabbits in Inner Mongolia, China and its successful propagation in A549 and PLC/PRF/5 cells
    Jirintai S, Jinshan, Tanggis Manglai D, Mulyanto, Takahashi M, Nagashima S, Kobayashi T, Nishizawa T, Okamoto H
    Virus Res 170(1-2) 126-137 2012
  • Molecular epidemiology and genetic histry of European-type genotype 3 hepatitis E virus indigeized in the central region of Japan
    Nakano T, Okano H, Kobayashi M, Ito K, Ohmori S, Nomura T, Kato H, Ayada M, Nakano Y, Akachi S, Sugimoto K, Fujita N, Shiraki K, Takei Y, Takahashi M, Okamoto H
    Infect Genet Evol 12(7) 1524-1534 2012
  • Icteric acute hepatitis E with no response of immunoglobulin M class anti-hepatitis E virus antibody
    Takikawa T, Miyamoto Y, Onodera M, Kuroda H, Kasai K, Miyasaka A, Takahashi M, Okamoto H, Suzuki K
    Hepatol Res 42(11) 1146-1149 2012
  • A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains: demonstration of HEV infectivity of porcine liver sold as food
    Takahashi H, Tanaka T, Jirintai, S, Nagashima S, Takahashi M, Nishizawa T, Misuo H, Yazaki Y, Okamoto H
    Arch Virol 157(2) 235-246 2012
  • Tumor susceptibility gene 101 and vacuolar protein sorting pathway are required for release of hepatitis E virions
    Nagashima S, Takahashi M, Jirintai S, Tanaka T, Nishizawa T, Yasuda J, Okamoto H
    J Gen Virol 92(12) 2838-2848 2011
  • Identification and characterization of a natural inter-genotypic (2b/1b) recombinant hepatitis C virus in Japan
    Yokoyama K, Takahashi M, Nishizawa T, Nagashima S, Jirintai S, Yotsumoto S, Okamoto H, Momoi MY
    Arch Virol 156(9) 1591-1601 2011
  • A nationwide survey of hepatitis E virus (HEV) infection in wild boars in Japan: identification of boar HEV strains of genotype 3 and genotype 4 and unrecognized genotypes
    Sato Y, Sato H, Naka K, Furuya S, Tsukiji H, Kitagawa K, Sonoda Y, Usui T, Sakamoto H, Yoshino S, Shimizu Y, Takahashi M, Nagashima S, Jirintai, Nishizawa T, Okamoto H
    Arch Virol 156(8) 1345-1358 2011
  • Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype
    Takahashi M, Nishizawa T, Sato H, Sato Y, Jirintai, Nagashima S, Okamoto H
    J Gen Virol 92(4) 902-908 2011
  • Analysis of the full-length genome of novel hepatitis B virus subgenotypes C11 and C12 in Papua, Indonesia
    Mulyanto, Depamede SN, Wahyono A, Jirintai, Nagashima S, Takahashi M, Okamoto H
    J Med Virol 83(1) 54-64 2011
Display all
Papers(paper)close
  • Frequent detection and characterization of hepatitis E virus variants in wild rats (Rattus rattus) in Indonesia
    Mulyanto, Depamede SN, Sriasih M, Takahashi M, Nagashima S, Jirintai S, Nishizawa T, Okamoto H
    Arch Virol 158(1) 87-96 2012
  • Molucular analysis of hepatitis E virus from farm rabbits in Inner Mongolia, China and its successful propagation in A549 and PLC/PRF/5 cells
    Jirintai S, Jinshan, Tanggis Manglai D, Mulyanto, Takahashi M, Nagashima S, Kobayashi T, Nishizawa T, Okamoto H
    Virus Res 170(1-2) 126-137 2012
  • Molecular epidemiology and genetic histry of European-type genotype 3 hepatitis E virus indigeized in the central region of Japan
    Nakano T, Okano H, Kobayashi M, Ito K, Ohmori S, Nomura T, Kato H, Ayada M, Nakano Y, Akachi S, Sugimoto K, Fujita N, Shiraki K, Takei Y, Takahashi M, Okamoto H
    Infect Genet Evol 12(7) 1524-1534 2012
  • Icteric acute hepatitis E with no response of immunoglobulin M class anti-hepatitis E virus antibody
    Takikawa T, Miyamoto Y, Onodera M, Kuroda H, Kasai K, Miyasaka A, Takahashi M, Okamoto H, Suzuki K
    Hepatol Res 42(11) 1146-1149 2012
  • A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains: demonstration of HEV infectivity of porcine liver sold as food
    Takahashi H, Tanaka T, Jirintai, S, Nagashima S, Takahashi M, Nishizawa T, Misuo H, Yazaki Y, Okamoto H
    Arch Virol 157(2) 235-246 2012
  • Tumor susceptibility gene 101 and vacuolar protein sorting pathway are required for release of hepatitis E virions
    Nagashima S, Takahashi M, Jirintai S, Tanaka T, Nishizawa T, Yasuda J, Okamoto H
    J Gen Virol 92(12) 2838-2848 2011
  • Identification and characterization of a natural inter-genotypic (2b/1b) recombinant hepatitis C virus in Japan
    Yokoyama K, Takahashi M, Nishizawa T, Nagashima S, Jirintai S, Yotsumoto S, Okamoto H, Momoi MY
    Arch Virol 156(9) 1591-1601 2011
  • A nationwide survey of hepatitis E virus (HEV) infection in wild boars in Japan: identification of boar HEV strains of genotype 3 and genotype 4 and unrecognized genotypes
    Sato Y, Sato H, Naka K, Furuya S, Tsukiji H, Kitagawa K, Sonoda Y, Usui T, Sakamoto H, Yoshino S, Shimizu Y, Takahashi M, Nagashima S, Jirintai, Nishizawa T, Okamoto H
    Arch Virol 156(8) 1345-1358 2011
  • Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype
    Takahashi M, Nishizawa T, Sato H, Sato Y, Jirintai, Nagashima S, Okamoto H
    J Gen Virol 92(4) 902-908 2011
  • Analysis of the full-length genome of novel hepatitis B virus subgenotypes C11 and C12 in Papua, Indonesia
    Mulyanto, Depamede SN, Wahyono A, Jirintai, Nagashima S, Takahashi M, Okamoto H
    J Med Virol 83(1) 54-64 2011
  • A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells
    Nagashima S, Takahashi M, Jirintai, Tanaka T, Yamada K, Nishizawa T, Okamoto H
    J Gen Virol 92(2) 269-278 2011
  • Identification and characterization of novel hepatitis B virus subgenotypes C10 in Nusa Tenggara, Indonesia
    Mulyanto, Depamede SN, Surayah K, Tjahyono AAH, Jirintai, Nagashima S, Takahashi M, Okamoto H
    Arch Virol 155(5) 705-715 2010
  • Hepatitis-associated aplastic anemia during a primary infection of genotype 1a torque teno virus
    Ishimura M, Ohga S, Ichiyama M, Kusuhara K, Takada H, Hara T, Takahashi M, Okamoto H
    Eur J Pediatr 169(7) 899-902 2010
  • Molecular and serological survey of hepatitis E virus infection among domestic pigs in Inner Mongolia, China
    Jinshan, Jirintai, Manglai D, Takahashi M, Nagashima S, Okamoto H
    Arch Virol 155(8) 1217-1226 2010
  • Hepatitis E virus (HEV) strains in serum samples can replicate efficiently in cultured cells despite the coexistence of HEV antibodies: characterization of HEV virions in blood circulation
    Takahashi M, Tanaka T, Takahashi H, Hoshino Y, Nagashima S, Jirintai, Mizuo H, Yazaki Y, Takagi T, Azuma M, Kusano E, Isoda N, Sugano K, Okamoto H
    J Clin Microbiol 48(48) 1112-1125 2010
  • A nationwide survey of hepatitis E virus infection in the general population of Japan
    Takahashi M, Tamura K, Hoshino Y, Nagashima S, Yazaki Y, Mizuo H, Iwamoto S, Okayama M, Nakamura Y, Kajii E, Okamoto H
    J Med Virol 82(2) 271-281 2010
  • A case of acute hepatitis C caused by interspousal transmission after 30 years of marrige
    Nishimura N, Isoda N, Higashizawa T, Otake T, Tsukui M, Nagashima S, Takahashi M, Okamoto H, Sugano K
    Clin J Gastroenterol 3(1) 50-561 2010
  • Hepatitis A and E virus infections among children in Mongolia
    Davaalkham D, Enkhoyun T, Takahashi M, Nakamura Y, Okamoto H
    Am J Trop Med Hyg 81(2) 248-251 2009
  • Determination of the 5’-terminal sequence of subgenomic RNA of hepatitis E virus strains in cultured cells
    Ichiyama K, Yamada K, Tanaka T, Nagashima S, Jirinta, Takahashi M, Okamoto H
    Arch Virol 154(12) 1945-1951 2009
  • ORF3 protein of hepatitis E virus is essential for virion release from infected cells
    Yamada K, Takahashi M, Hoshino Y, Takahashi H, Ichiyama K, Nagashima S, Tanaka T, Okamoto H
    J Gen Virol 90(8) 1880-1891 2009
  • Nucleotide substitutions of hepatitis E virus genomes associated with fulminant hepatitis and disease severity
    Inoue J, Takahashi M, Mizuo H, Suzuki K, Aikawa T, Shimosegawa T, Okamoto H
    Tohoku J Exp Med 218(4) 279-284 2009
  • Molecular analysis of transmission of hepatitis C virus in a nurse who acquired acute hepatitis C after caring for a viremic patient with epitaxis
    Toda T, Mitsui T, Tsukamoto Y, Ebara T, Hirose A, Masuko K, Nagashima S, Takahashi M, Okamoto H
    J Med Virol 81 1363-1370 2009
  • No evidence for patient-to-patient transmission of hepatitis C virus during upper gastrointestinal endoscopy: molecular studies on three acute hepatitis C patients
    Toda T, Mitsui T, Tsukamoto Y, Ebara T, Masuko K, Takahashi M, Okamoto H
    Digest endoscopy 21(3) 147-153 2009
  • A nationwide molecular epidemiological study on hepatitis B virus in Indonesia: identification of two novel subgenotypes, B8 and C7
    Mulyanto, Depamede SN, Surayah K, Tsuda F, Ichiyama K, Takahashi M, Okamoto H
    Arch Virol 154(7) 1047-1059 2009
  • Development and characterization of a genotype 4 hepatitis E virus cell culture system using a HE-JF5/15F strain recovered from a fulminant hepatitis patient
    Tanaka T, Takahashi M, Takahashi H, Ichiyama K, Hoshino Y, Nagashima S, Mizuo H, Okamoto H
    J Clin Microbiol 47(6) 1906-1910 2009
  • Sporadic acute hepatitis E occurred constantly during the last decade in northeast Japan
    Inoue J, Ueno Y, Kogure T, Nagasaki F, Akahane T, Fukushima K, Kogure T, Kondo Y, Kakazu E, Tamai K, Kido O, Nakagome Y, Ninomiya M, Obara N, Wakui Y, Takahashi M, Okamoto H, Shimosegawa T
    J Gastroenterol 44(4) 329-337 2009
  • Prevalence of antibodies to hepatitis E virus among Japanese blood donors: identification of three blood donors infected with a genotype 3 hepatitis E virus
    Fukuda S, Sunaga J, Saito N, Fujimura K, Itoh Y, Sasaki M, Tsuda F, Takahashi M, Nishizawa T, Okamoto H
    J Med Virol 73 544-561 2004
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015
  • Two cases of sporadic acute hepatitis E in Mie, Japan who were infected with subgenotype 1a hepatitis E virus
    Okano Hiroshi;Maekawa Tadashi;Kobayashi Makoto;Yamawaki Makoto;Ninomiya Jun;Nakano Tatsunori;Uraki Satoko;Tanaka Hideaki;Shiraki Katsuya;Takei Yoshiyuki;Takahashi Masaharu;Okamoto Hiroaki
    Kanzo 57(2) 81-88 2016
  • Metachronous occurrence of two cases of acute hepatitis E after eating raw pig liver and heart at the same restaurant at Gifu city in Japan
    Shimizu Shogo;Sugihara Junichi;Suzuki Yusuke;Nishigaki Yoichi;Takahashi Masaharu;Takahashi Kazuaki;Nakano Tatsunori;Hayashi Hideki;Kato Tomohiro;Tomita Eiichi;Arai Masahiro;Okamoto Hiroaki
    Kanzo 56(11) 617-620 2015
  • Characteristics of 20 Patients with Autochthonous Acute Hepatitis E in Hokkaido, Japan: First Report of Bilateral Facial Palsy Following the Infection with Genotype 4 Hepatitis E Virus
    Yazaki Yasuyuki;Sugawara Kenji;Honda Mitsunori;Ohnishi Hiroshi;Nagashima Shigeo;Takahashi Masaharu;Okamoto Hiroaki
    Tohoku J. Exp. Med. 236(4) 263-271 2015
  • Serum Torque Teno Virus DNA Titer in Idiopathic Pulmonary Fibrosis Patients with Acute Respiratory Worsening
    Bando Masashi;Nakayama Masayuki;Takahashi Masaharu;Hosono Tatsuya;Mato Naoko;Yamasawa Hideaki;Okamoto Hiroaki;Sugiyama Yukihiko
    Japanese Journal of Medicine 54(9) 1015-1019 2015

Papers(other)

  • High prevalence of antibodies to hepatitis A and E viruses and viremia of hepatitis B, C, and D viruses among apparently healthy populations in Mongolia
    Clin Diagn Lab Immunol 11:392-398 2004
  • Swine hepatitis E virus strains in Japan form four phylogenetic clusters comparable with those of Japanese isolates of human hepatitis E virus
    J Gen Virol 84, 851-862 2003
  • Identification of two distinct genotypes of hepatitis E virus in a Japanese patient with acute hepatitis who had not travelled abroad
    J Gen Virol 83, 1931-1940 2002
  • Identification of a genotypeⅢ swine hepatitis E virus that was isolated from a Japanese pig born in 1990 and that is most closely related to Japanese isolates of human hepatitis E virus
    J Clin Microbiol 41, 1342-1343 2003
  • TT virus is distributed in various leukocyte subpopulations at distinct levels,with the highest viral load in granulocytes
    Biochem Biophys Res Commun 290, 242-248 2002
  • E型肝炎研究の新しい展開
    最新医学 59:52-58 2004
  • E型肝炎のウイルス学的診断
    肝胆膵 47:647-656 2003
  • Prevalence of antibodies to hepatitis E virus among Japanese blood donors: identification of three blood donors infected with a genotype 3 hepatitis E virus "Jointly worked"
    J Med Virol 73:554-561 2004
  • Prevalence of hepatitis E virus infection among hemodialysis patients in Japan: evidence for infection with a genotype 3 HEV by blood transfusion "Jointly worked"
    J Med Virol 74:563-572 2004
  • Prevalence of hepatitis E virus (HEV) infection in wild boars and deer genetic identification of a genotype 3 HEV from a boar in Japan "Jointly worked"
    J Clin Microbiol 42:5371-5374 2004
Display all
Papers(other)close
  • High prevalence of antibodies to hepatitis A and E viruses and viremia of hepatitis B, C, and D viruses among apparently healthy populations in Mongolia
    Clin Diagn Lab Immunol 11:392-398 2004
  • Swine hepatitis E virus strains in Japan form four phylogenetic clusters comparable with those of Japanese isolates of human hepatitis E virus
    J Gen Virol 84, 851-862 2003
  • Identification of two distinct genotypes of hepatitis E virus in a Japanese patient with acute hepatitis who had not travelled abroad
    J Gen Virol 83, 1931-1940 2002
  • Identification of a genotypeⅢ swine hepatitis E virus that was isolated from a Japanese pig born in 1990 and that is most closely related to Japanese isolates of human hepatitis E virus
    J Clin Microbiol 41, 1342-1343 2003
  • TT virus is distributed in various leukocyte subpopulations at distinct levels,with the highest viral load in granulocytes
    Biochem Biophys Res Commun 290, 242-248 2002
  • E型肝炎研究の新しい展開
    最新医学 59:52-58 2004
  • E型肝炎のウイルス学的診断
    肝胆膵 47:647-656 2003
  • Prevalence of antibodies to hepatitis E virus among Japanese blood donors: identification of three blood donors infected with a genotype 3 hepatitis E virus "Jointly worked"
    J Med Virol 73:554-561 2004
  • Prevalence of hepatitis E virus infection among hemodialysis patients in Japan: evidence for infection with a genotype 3 HEV by blood transfusion "Jointly worked"
    J Med Virol 74:563-572 2004
  • Prevalence of hepatitis E virus (HEV) infection in wild boars and deer genetic identification of a genotype 3 HEV from a boar in Japan "Jointly worked"
    J Clin Microbiol 42:5371-5374 2004
  • Presence of antibodies to hepatitis E virus in Japanese pet cats "Jointly worked"
    Infection 32:57-58 2004
  • Three male patients with sporadic acute hepatitis E in Sendai, Japan, who were domestically infected with hepatitis E of genotype III or IV "Jointly worked"
    J Gastroenterol 39:292-298 2004
  • Infection of a Japanese patient by genotype 4 hepatitis E virus while traveling in Vietnam "Jointly worked"
    J Clin Microbiol 42:3883-3885 2004
  • Molecular investigation of hepatitis E virus infection in domestic and miniature pigs used for medical experiment "Jointly worked"
    Xenotransplantation 11:503-510 2004
  • Prevalence of antibodies to hepatitis E virus among apparently healthy humans and pigs in Bali, Indonesia: identification of a pig infected with a genotype 4 hepatitis E virus "Jointly worked"
    J Med Virol 73:38-44 2004
  • Genetic changes in hepatitis E virus of subtype 1a in patients with sporadic acute hepatitis E in Kathmandu, Nepal, from 1997 to 2002 "Jointly worked"
    J Gen Virol 85:97-104 2004
  • Characterization of Japanese swine and human hepatitis E virus isolates of genotypeⅣ with 99% identity over the entire genome "Jointly worked"
    J Gen Virol 84, 1245-1251 2003
  • Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food "Jointly worked"
    J Gen Virol 84, 2351-2357 2003
  • Features of hepatitis E virus infection in Japan "Jointly worked"
    Intern Med 42:1065-1071 2003
  • Molecular investivation of hepatitis E virus infection in patients with acute hepatitis in Kathmandu, Nepal "jointly worked"
    J Med Virol 69, 207-214 2003
  • Molecular and serological characterization of sporadic acute hepatitis E in Japanese patient infected with a genotypeⅢ hepatitis E virus in 1993 "Jointly worked"
    J Gen Virol 84, 421-427 2003
  • Idenification of indigenous hepatitis E virus from a japanese patient who contraced sporadic acute hepatitis in 1982(共著)
    J Inf Dis 186, 1535-1536 2002
  • Polyphyletic strains of hepatitis E virus are responsible for sporadic cases of acute hepatitis in Japan(共著)
    J Clin Microbiol 40, 3209-3218 2002
  • High TT virus load as an independentt foctor asscoated with the occurrence of hepatocellular carcinoma among patients with hepatitis C virus-related chronic liver disease(共著)
    J Med Virol 67, 501-509 2002
  • TT virus of certain genotypes may reduce the platelet count in patients who achieve a sustained virologic response to interferon treatment for chronic hepatitis C(共著)
    Hepatol Res 23, 105-114 2002
  • Genetic characterization of TT viruses (TTVs) in pigs,cats and dogs and their relatedness with species-specific to TTVs in primates and tupaias(共著)
    J Gen Virol 83, 1291-1297 2002
  • Anaysis of the complete genome of indigenous swine hepatitis E virus isolated in Japan(共著)
    Biochem Biophys Res Commun 289, 929-936 2001
  • Infection of TT virus in patients with idiopathic pulmonary fibrosis(共著)
    Resp Med 95, 935-942 2001
  • Analysis of the entire genomes of thirteen TT virus variants classifiable into the fourth and fifth genomic groups,isolated from viremic infants(共著)
    Arch Virol 147, 21-41 2001
  • Heterogeneous distribution of TT virus of distinct genotypes in multiple tissues from infectedd humans(共著)
    Virology 288, 358-368 2001
  • Genomic and evolutionary chracterization of TT virus (TTV) in tupias and comparison with speces-specific TTVs in humans and non-human primates(共著)
    J Gen Virol 82, 2041-2050 2001
  • Molecular epidemiology of TT virus (TTV) and characterization of two novel TTV genotypes in Indonesia(共著)
    Arch Virol 146, 1249-1266 2001
  • Influence of TT virus infection on the thrombocytepenia of patients with chronic liver disease(共著)
    Hepatol Res 20, 288-300 2001
  • Inverse relationship between the tire of TT virus DNA and the CD4 cell count in patients infected with HIV(共著)
    AIDS 15, 197-211 2001
  • Influence of TT virus on the histopathlogical features of nonalocoholic fatty liver disease(共著)
    Hepatol Res 19, 197-211 2001
  • Influence of TT virus on the clinical courese of alcoholic liver disease(共著)
    Hepatol Res 19, 180-193 2001
  • IgM-class antibodies to TT virus (TTV) in patients acute TTV infection(共著)
    Hepatol Res 19, 1-11 2001
  • Visualization of TT virus particles recovered from the sera and feces of infected humans(共著)
    Bicohem Biophys Res Commun 279, 718-724 2000
  • TT virus mRNAs detected in the bone marrow cells from an infected individual(共著)
    Biochem Biophys Res Commun 279, 700-707 2000
  • Transmission of TT virus of genotype la to chimpanzees with fecal supernatant or serum from patients with acute TTV infection(共著)
    Bicohem Biophys Res Commun 278, 470-476 2000
  • Species-specific TT virus in humans and nonhuman primates and their phylogenetic relatedness(共著)
    Virology 277,368-378 2000
  • Sequestration of TT virus of restriced genotypes in peripheral blood mononuclear cells(共著)
    J Virol 74, 10236-10239 2000
  • The entire nucleotide sequences of two distinct TT virus (TTV) isolates (TJN01 and TJN02) remotely related to the original TTV isolates(共著)
    Arch Virol 145, 1543-1559 2000
  • Replicative forms of TT virus DNA in bone marrow cells(共著)
    Biochem Biophys Res Commun 657-662 2000
  • Infleuence of PCR primers on the detection of TT virus DNA in blood donors(共著)
    J Infect Dis 180,1750-1751 1999
  • Marked genomic heterogeneity and frequent mixed infection of TT virus demonstrated by PCR with primers from coding and noncoding regions(共著)
    Virology 259, 428-436 1999
  • The entire nucleotide sequence of a TT virus isolate from the United States (TUS01):compraison with reported isolates and phylogenetic analysis(共著)
    Virology 259, 437-448 1999

Outside Fund Adoption

  • Medical ecology of hepatitis viruses
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Outside Fund Adoptionclose
  • Medical ecology of hepatitis viruses


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