kasashima katsumi

FacultyDepartomentofBiochemistryDivisionofFunctionalBiochemistry
Job titleAssistant ProfessorWeb site

Profile

Research Keywords

    Mitochondrial DNA, Mitochondria, RNA-processing

Research Areas

  • Biological science / Molecular biology
  • Basic medicine / Pathological medical chemistry

Career

  • Jichi Medical University, Assistant Professor

Academic Societies

  • THE JAPANESE BIOCHEMICAL SOCIETY
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Academic Societiesclose
  • THE JAPANESE BIOCHEMICAL SOCIETY

Research Activities

Papers(paper)

  • Establishment of a specific cell death induction system in Bombyx mori by a transgene with the conserved apoptotic regulator, mouse Bcl-2-associated X protein (mouse Bax).
    Sumitani M, Sakurai T, Kasashima K, Kobayashi S, Uchino K et al.
    Insect Mol. Biol. 24(6) 671-680 Dec. 2015
  • Interaction of human mitochondrial transcription factor A in mitochondria: its involvement in the dynamics of mitochondrial DNA nucleoids.
    Kasashima K, Endo H
    Genes to cells : devoted to molecular & cellular mechanisms Oct. 2015
  • Dynamic regulation of mitochondrial genome maintenance in germ cells.
    Kasashima K, Nagao Y, Endo H
    Reproductive medicine and biology 13 11-20 2014
  • Paraneoplastic cerebellar degeneration associated with an onconeural antibody against creatine kinase, brain-type.
    Tetsuka S, Tominaga K, Ohta E, Kuroiwa K, Sakashita E, Kasashima K, Hamamoto T, Namekawa M, Morita M, Natsui S, Morita T, Tanaka K, Takiyama Y, Nakano I, Endo H
    Journal of the neurological sciences 335(1-2) 48-57 2013
  • Reduction of malaria transmission by transgenic mosquitoes expressing an antisporozoite antibody in their salivary glands.
    Sumitani M, Kasashima K, Yamamoto DS, Yagi K, Yuda M, Matsuoka H, Yoshida S
    Insect molecular biology 22(1) 41-51 2013
  • Translational repression of the McKusick-Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites.
    Akimoto C, Sakashita E, Kasashima K, Kuroiwa K, Tominaga K, Hamamoto T, Endo H
    Biochimica et biophysica acta 1830(3) 2728-2738 2013
  • Maintenance of mitochondrial genome distribution by mitochondrial AAA+ protein ClpX.
    Kasashima K, Sumitani M, Endo H
    Experimental cell research 318(18) 2335-2343 2012
  • Biochemical properties of Caenorhabditis elegans HMG-5, a regulator of mitochondrial DNA.
    Sumitani M, Kasashima K, Matsugi J, Endo H
    Journal of biochemistry 149(5) 581-589 2011
  • Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B.
    Fujiwara Y, Kasashima K, Saito K, Fukuda M, Fukao A, Sasano Y, Inoue K, Fujiwara T, Sakamoto H
    Biochimie 93(5) 817-822 2011
  • Human mitochondrial transcription factor A is required for the segregation of mitochondrial DNA in cultured cells.
    Kasashima K, Sumitani M, Endo H
    Experimental cell research 317(2) 210-220 2011
Display all
Papers(paper)close
  • Establishment of a specific cell death induction system in Bombyx mori by a transgene with the conserved apoptotic regulator, mouse Bcl-2-associated X protein (mouse Bax).
    Sumitani M, Sakurai T, Kasashima K, Kobayashi S, Uchino K et al.
    Insect Mol. Biol. 24(6) 671-680 Dec. 2015
  • Interaction of human mitochondrial transcription factor A in mitochondria: its involvement in the dynamics of mitochondrial DNA nucleoids.
    Kasashima K, Endo H
    Genes to cells : devoted to molecular & cellular mechanisms Oct. 2015
  • Dynamic regulation of mitochondrial genome maintenance in germ cells.
    Kasashima K, Nagao Y, Endo H
    Reproductive medicine and biology 13 11-20 2014
  • Paraneoplastic cerebellar degeneration associated with an onconeural antibody against creatine kinase, brain-type.
    Tetsuka S, Tominaga K, Ohta E, Kuroiwa K, Sakashita E, Kasashima K, Hamamoto T, Namekawa M, Morita M, Natsui S, Morita T, Tanaka K, Takiyama Y, Nakano I, Endo H
    Journal of the neurological sciences 335(1-2) 48-57 2013
  • Reduction of malaria transmission by transgenic mosquitoes expressing an antisporozoite antibody in their salivary glands.
    Sumitani M, Kasashima K, Yamamoto DS, Yagi K, Yuda M, Matsuoka H, Yoshida S
    Insect molecular biology 22(1) 41-51 2013
  • Translational repression of the McKusick-Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites.
    Akimoto C, Sakashita E, Kasashima K, Kuroiwa K, Tominaga K, Hamamoto T, Endo H
    Biochimica et biophysica acta 1830(3) 2728-2738 2013
  • Maintenance of mitochondrial genome distribution by mitochondrial AAA+ protein ClpX.
    Kasashima K, Sumitani M, Endo H
    Experimental cell research 318(18) 2335-2343 2012
  • Biochemical properties of Caenorhabditis elegans HMG-5, a regulator of mitochondrial DNA.
    Sumitani M, Kasashima K, Matsugi J, Endo H
    Journal of biochemistry 149(5) 581-589 2011
  • Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B.
    Fujiwara Y, Kasashima K, Saito K, Fukuda M, Fukao A, Sasano Y, Inoue K, Fujiwara T, Sakamoto H
    Biochimie 93(5) 817-822 2011
  • Human mitochondrial transcription factor A is required for the segregation of mitochondrial DNA in cultured cells.
    Kasashima K, Sumitani M, Endo H
    Experimental cell research 317(2) 210-220 2011
  • Association of a novel mitochondrial protein M19 with mitochondrial nucleoids.
    Sumitani M, Kasashima K, Ohta E, Kang D, Endo H
    Journal of biochemistry 146(5) 725-732 2009
  • Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids.
    Kasashima K, Sumitani M, Satoh M, Endo H
    Experimental cell research 314(5) 988-996 2008
  • Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2.
    Kasashima K, Ohta E, Kagawa Y, Endo H
    The Journal of biological chemistry 281(47) 36401-36410 2006
  • Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells.
    Kasashima K, Nakamura Y, Kozu T
    Biochemical and biophysical research communications 322(2) 403-410 2004
  • Discrimination of target by siRNA: designing of AML1-MTG8 fusion mRNA-specific siRNA sequences.
    Kasashima K, Sakota E, Kozu T
    Biochimie 86 713-721 2004
  • Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins.
    Kasashima K, Sakashita E, Saito K, Sakamoto H
    Nucleic acids research 30(20) 4519-4526 2002
  • Cytoplasmic localization is required for the mammalian ELAV-like protein HuD to induce neuronal differentiation.
    Kasashima K, Terashima K, Yamamoto K, Sakashita E, Sakamoto H
    Genes to cells : devoted to molecular & cellular mechanisms 4(11) 667-683 1999
  • Characterization of Bombyx mori mitochondrial transcription factor A, a conserved regulator of mitochondrial DNA.
    Sumitani M, Kondo M, Kasashima K, Endo H, Nakamura K, Misawa T, Tanaka H, Sezutsu H
    Gene 608 103-113 Apr. 2017
  • Inhibition of Malaria Infection in Transgenic Anopheline Mosquitoes Lacking Salivary Gland Cells.
    Yamamoto DS, Sumitani M, Kasashima K, Sezutsu H, Matsuoka H
    PLoS pathogens 12(9) e1005872 Sep. 2016
  • Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.
    Mashiko T, Sakashita E, Kasashima K, Tominaga K, Kuroiwa K, Nozaki Y, Matsuura T, Hamamoto T, Endo H
    The Journal of biological chemistry 291(29) 14996-15007 Jul. 2016

Papers(other)

  • [Structures and functions of RNA-binding proteins].
    Kasashima K, Sakamoto H
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 48 390-397 Mar. 2003
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Papers(other)close
  • [Structures and functions of RNA-binding proteins].
    Kasashima K, Sakamoto H
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 48 390-397 Mar. 2003

Outside Fund Adoption

  • Maintenance of mitochondrial genome, Mitochondrial RNA biology
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Outside Fund Adoptionclose
  • Maintenance of mitochondrial genome, Mitochondrial RNA biology


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