morita mitsuya

FacultyRehabilitation
Job titleAssociate ProfessorWeb site

Profile

Research Keywords

    Neurology, Genetics

Research Areas

  • Basic medicine / Human genetics
  • Clinical internal medicine / Neurology

Research Activities

Papers(paper)

  • Creatinine/cystatin C ratio as a surrogate marker of residual muscle mass in Amyotrophic lateral sclerosis.
    S. Tetsuka, M. Morita, K. Ikeguchi, I. Nakano
    Neurology and Clinical Neuroscience. 1(1) 32-37 2013
  • Clinical features and a mutation with late onset of limb girdle muscular dystrophy 2B
    Takahashi T, Aoki M, Suzuki N, Tateyama M, Yaginuma C, Sato H, Hayasaka M, Sugawara H, Ito M, Abe-Kondo E, Shimakura N, Ibi T, Kuru S, Wakayama T, Sobue G, Fujii N, Saito T, Matsumura T, Funakawa I, Mukai E, Kawanami T, Morita M, Yamazaki M, Hasegawa T, Shimizu J, Tsuji S, Kuzuhara S, Tanaka H, Yoshioka M, Konno H, Onodera H, Itoyama Y.
    J Neurol Neurosurg Psychiatry. 84(4) 433-440 2013
  • Progressive aphasia as the presenting symptom in a patient with amyotrophic lateral sclerosis with a novel mutation in the OPTN gene.
    Czell D., Andersen P.M., Neuwirth C., Morita M., Weber M.
    14(2) 138-140 2013
  • Tracheostomy with invasive ventilation for ALS patients: Neurologists' roles in the US and Japan.
    Rabkin J, Ogino M, Goetz R, McElhiney M, Marziliano A, Imai T, Atsuta N, Morita M, Tateishi T, Matsumura T, Mitsumoto H
    Amyotroph Lateral Scler Frontotemporal Degener. 14(2) 116-123 2013
  • ZNF512B gene is a prognostic factor in patients with amyotrophic lateral sclerosis.
    Tetsuka S, Morita M, Iida A, Uehara R, Ikegawa S, Nakano I.
    J Neurol Sci. 324(1-2) 163-166 2013
  • Analysis of C9orf72 repeat expansion in 563 Japanese patients with amyotrophic lateral sclerosis.
    Ogaki K, Li Y, Atsuta N, Tomiyama H, Funayama M, Watanabe H, Nakamura R, Yoshino H, Yato S, Tamura A, Naito Y, Taniguchi A, Fujita K, Izumi Y, Kaji R, Hattori N, Sobue G
    Neurobiol Aging 33(10) e11-e16 2012
  • A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
    Iida A, Takahashi A, Kubo M, Saito S, Hosono N, Ohnishi Y, Kiyotani K, Mushiroda T, Nakajima M, Ozaki K, Tanaka T, Tsunoda T, Oshima S, Sano M, Kamei T, Tokuda T, Aoki M, Hasegawa K, Mizoguchi K, Morita M, Takahashi Y, Katsuno M, Atsuta N, Watanabe H, Tanaka F, Kaji R, Nakano I, Kamatani N, Tsuji S, Sobue G, Nakamura Y, Ikegawa S
    Hum Mol Genet. 20(18) 3684-3692 2011
  • Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians
    Iida A, Takahashi A, Deng M, Zhang Y, Wang J, Atsuta N, Tanaka F, Kamei T, Sano M, Oshima S, Tokuda T, Morita M, Akimoto C, Nakajima M, Kubo M, Kamatani N, Nakano I, Sobue G, Nakamura Y, Fan D and Ikegawa S
    Neurobiology of Aging 32(4) e13-e14 2011
  • High-Resolution Melting (HRM) Analysis of the Cu/Zn Superoxide Dismutase (SOD1) Gene in Japanese Sporadic Amyotrophic Lateral Sclerosis (SALS) Patients.
    Akimoto C, Morita M, Atsuta N, Sobue G, Nakano I:
    Neurol Res Int 165415 2011
  • Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial.
    Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G; Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group
    Lancet Neurol 9(9) 875-884 2010
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Papers(paper)close
  • Creatinine/cystatin C ratio as a surrogate marker of residual muscle mass in Amyotrophic lateral sclerosis.
    S. Tetsuka, M. Morita, K. Ikeguchi, I. Nakano
    Neurology and Clinical Neuroscience. 1(1) 32-37 2013
  • Clinical features and a mutation with late onset of limb girdle muscular dystrophy 2B
    Takahashi T, Aoki M, Suzuki N, Tateyama M, Yaginuma C, Sato H, Hayasaka M, Sugawara H, Ito M, Abe-Kondo E, Shimakura N, Ibi T, Kuru S, Wakayama T, Sobue G, Fujii N, Saito T, Matsumura T, Funakawa I, Mukai E, Kawanami T, Morita M, Yamazaki M, Hasegawa T, Shimizu J, Tsuji S, Kuzuhara S, Tanaka H, Yoshioka M, Konno H, Onodera H, Itoyama Y.
    J Neurol Neurosurg Psychiatry. 84(4) 433-440 2013
  • Progressive aphasia as the presenting symptom in a patient with amyotrophic lateral sclerosis with a novel mutation in the OPTN gene.
    Czell D., Andersen P.M., Neuwirth C., Morita M., Weber M.
    14(2) 138-140 2013
  • Tracheostomy with invasive ventilation for ALS patients: Neurologists' roles in the US and Japan.
    Rabkin J, Ogino M, Goetz R, McElhiney M, Marziliano A, Imai T, Atsuta N, Morita M, Tateishi T, Matsumura T, Mitsumoto H
    Amyotroph Lateral Scler Frontotemporal Degener. 14(2) 116-123 2013
  • ZNF512B gene is a prognostic factor in patients with amyotrophic lateral sclerosis.
    Tetsuka S, Morita M, Iida A, Uehara R, Ikegawa S, Nakano I.
    J Neurol Sci. 324(1-2) 163-166 2013
  • Analysis of C9orf72 repeat expansion in 563 Japanese patients with amyotrophic lateral sclerosis.
    Ogaki K, Li Y, Atsuta N, Tomiyama H, Funayama M, Watanabe H, Nakamura R, Yoshino H, Yato S, Tamura A, Naito Y, Taniguchi A, Fujita K, Izumi Y, Kaji R, Hattori N, Sobue G
    Neurobiol Aging 33(10) e11-e16 2012
  • A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
    Iida A, Takahashi A, Kubo M, Saito S, Hosono N, Ohnishi Y, Kiyotani K, Mushiroda T, Nakajima M, Ozaki K, Tanaka T, Tsunoda T, Oshima S, Sano M, Kamei T, Tokuda T, Aoki M, Hasegawa K, Mizoguchi K, Morita M, Takahashi Y, Katsuno M, Atsuta N, Watanabe H, Tanaka F, Kaji R, Nakano I, Kamatani N, Tsuji S, Sobue G, Nakamura Y, Ikegawa S
    Hum Mol Genet. 20(18) 3684-3692 2011
  • Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians
    Iida A, Takahashi A, Deng M, Zhang Y, Wang J, Atsuta N, Tanaka F, Kamei T, Sano M, Oshima S, Tokuda T, Morita M, Akimoto C, Nakajima M, Kubo M, Kamatani N, Nakano I, Sobue G, Nakamura Y, Fan D and Ikegawa S
    Neurobiology of Aging 32(4) e13-e14 2011
  • High-Resolution Melting (HRM) Analysis of the Cu/Zn Superoxide Dismutase (SOD1) Gene in Japanese Sporadic Amyotrophic Lateral Sclerosis (SALS) Patients.
    Akimoto C, Morita M, Atsuta N, Sobue G, Nakano I:
    Neurol Res Int 165415 2011
  • Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial.
    Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G; Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group
    Lancet Neurol 9(9) 875-884 2010
  • Inverse ocular bobbing in a patient with encephalitis associated with antibodies to the N-methyl-D-aspartate receptor.
    Shimazaki H, Morita M, Nakano I, Dalmau J.
    Arch Neurol. 65(9) 1251 2008
  • Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Buratti E, Baralle F, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H.
    Ann Neurol 64(1) 60-70 2008
  • Inverse ocular bobbing in a patient with encephalitis associated with antibodies to the N-methyl-D-aspartate receptor.
    Shimazaki H, Morita M, Nakano I, Dalmau J.
    Arch Neurol 65(9) 1251 2008
  • Constant blood flow reduction in premotor frontal lobe regions in ALS with dementia –a SPECT study with 3D-SSP.
    Ishikawa T, Morita M, Nkano I.
    Acta Neurol Scand 116 340-344 2007
  • Limited Wegener`s granulomatosis manifested by abducens nerve palsy resulting from pachymeningitis
    Kamimura T, Shimazaki H, Morita M, Nakano I, Okazaki H, Minota S
    12 259-260 2006
  • A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia
    Morita M, Al-Chalabi A, Andersen PM, Hosler B, Sapp P, Englund E, Mitchell JE, Habgood JJ, de Belleroche J, Xi J, Jongjaroenprasert W, Horvitz HR, Gunnarsson LG, Brown RH Jr.
    Neurology 66 839-844 2006
  • Polymerase chain reaction-based analysis using deaminated DNA of dodecamer expansions in CSTB, associated with Unverricht-Lundberg myoclonus epilepsy
    Horiuchi H, Osawa M, Furutani R, Morita M, Tian W, Awatsu Y, Shimazaki H, Umetsu K
    Genetic Testing 9 328-333 2005
  • A novel mutation in the spastin gene in a family with spastic paraplegia
    Morita M, Ho Mac, Hosler BA, McKenna-Yasek D, Brown RH Jr.
    Neurosci Lett. 325(1) 57-61 2002
  • Novel acceptor splice site mutation in the invariant AG of intron 6 of alpha-galactosidase A gene, causing Fabry disease.
    Matsumura T, Osaka H, Sugiyama N, Kawanishi C, Maruyama Y, Suzuki K, Onishi H, Yamada Y, Morita M, Aoki M, Kosaka, K
    Hum. Mutat. 11 483 1998
  • A novel mutation Asp90Val in the SOD1 gene associated with Japanese familial ALS.
    Morita M, Abe K, Takahashi M, Onodera Y, Okumura H, Niino M, Tashiro K, Nakano I, Itoyama, Y.
    Eur. J. Neurol. 5 389-392 1998
  • Maternal anticipation in Machado-Joseph disease (MJD): some maternal factors independent of the number of CAG repeat units may play a role in genetic anticipation in a Japanese MJD family.
    Takiyama Y, Shimazaki H, Morita M, Soutome M, Sakoe K, Esumi E, Muramatsu S, Yoshida M, Igarashi S, Tanaka H, Tsuji S, Sasaki H, Wakisaka A, Nakano I, Nishizawa, M
    J. Neurol. Sci. 155 141-145 1998
  • A novel two-base mutation in the Cu/Zn superoxide dismutase gene associated with familial amyotrophic lateral sclerosis in Japan.
    Morita M, Aoki M, Abe K, Hasegawa T, Sakuma R, Onodera Y, Ichikawa N, Nishizawa M, Itoyama Y.
    Neuroscience Letters 205 79-82 1996
  • Paraneoplastic limbic encephalitis-A case responsive to double filtration plasmapheresis and chemotherapy.
    Takeuchi Y, Doki T, Morita M, Fujimoto K, Ogawa M, Nishizawa M, Yoshida M, Muto S, Kusano E, Asano Y.
    Jpn J Apheresis 14(1) 57-58 1995
  • Expression of leukocyte chemotactic cytokines in myocardial tissue.
    Seino Y, Ikeda U, Sekiguchi H, Morita M, Konishi K, Kasahara T, Shimada K.
    Cytokine 7(3) 301-304 1995
  • Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-κB is target for glucocorticoid-mediated interleukin 8 gene repression.
    Mukaida N, Morita M, Ishikawa Y, Rice N, Okamoto S, Kasahara T, Matsushiam K.
    J. Biol. Chem. 269 13289-13295 1994
  • Induction and regulation of IL-8 and MCAF production in human brain tumor cell lines and brain tumor tissues.
    Morita M, Kasahara T, Mukaida N, Matsushima K, Nagashima T, Nishizawa M,Yoshida M.
    Eur. Cytokine Netw. 4 351-358 1993
  • Efficacy of plasma exchange and double filtration plasmapheresis on Guillain-Barre syndrome.
    Yoshida I, Ootaka S, Honma S, Takeda S, Tabei K, Asano Y, Morita M, Nishizawa M, Yoshida M
    Therapeutic Plasmapheresis 77-83 1993
  • Constant blood flow reduction in premotor frontal lobe regions in ALS with dementia –a SPECT study with 3D-SSP.
    Ishikawa T, Morita M, Nkano I.
    Acta Neurol Scand 116 340–344
  • Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Buratti E, Baralle F, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H.
    Ann Neurol. 64(1) 60-70

Conference Presentations

  • Molecular mechanism of interleukin8(IL-8)gene repression by a glucocorticoid.(共著)
    Combined Meeting 8th Intl' Lymphok. 4th Intl' Cytokine Workshop. 1993
  • Molecular mechanism of IL-8 gene repression by a glucocorticoid and FK506.(共著)
    Joint Meeting of AAI and Clin. Immunol. Society. 1993
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Conference Presentationsclose
  • Molecular mechanism of interleukin8(IL-8)gene repression by a glucocorticoid.(共著)
    Combined Meeting 8th Intl' Lymphok. 4th Intl' Cytokine Workshop. 1993
  • Molecular mechanism of IL-8 gene repression by a glucocorticoid and FK506.(共著)
    Joint Meeting of AAI and Clin. Immunol. Society. 1993

Book

  • Genetics of amyotrophic lateral sclerosis : an overview.(共著)
    Amyotrophic Lateral Sclerosis. London : Martin Dunitz 1999
  • Familial Amyotrophic Lateral Sclerosis: A Review
    Neuromuscular Diseases: From Basic Mechanisms to Clinical Management 2000
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  • Genetics of amyotrophic lateral sclerosis : an overview.(共著)
    Amyotrophic Lateral Sclerosis. London : Martin Dunitz 1999
  • Familial Amyotrophic Lateral Sclerosis: A Review
    Neuromuscular Diseases: From Basic Mechanisms to Clinical Management 2000

Outside Fund Adoption

  • Genetics in motor neuron disease
    :Gene Science Research
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  • Genetics in motor neuron disease
    :Gene Science Research


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