karasawa tadayoshi

FacultyDivisionofInflammationResearch
Job titleResearch AssociateWeb site

Profile

Research Areas

  • Clinical internal medicine / Metabolomics

Research Activities

Papers(paper)

  • Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury.
    Komada T, Usui F, Kawashima A, Kimura H, Karasawa T, Inoue Y, Kobayashi M, Mizushina Y, Kasahara T, Taniguchi S, Muto S, Nagata D, Takahashi M
    Scientific reports 5 10901 Jun. 2015
  • RIP140 as a novel therapeutic target in the treatment of atherosclerosis.
    Karasawa T, Takahashi M
    Journal of molecular and cellular cardiology 81 136-138 Apr. 2015
  • NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β.
    Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M
    The Journal of biological chemistry 290(8) 5065-5077 Feb. 2015
  • Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.
    Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
    Arteriosclerosis, thrombosis, and vascular biology 35(1) 127-136 Jan. 2015
  • Oligomerized CARD16 promotes caspase-1 assembly and IL-1β processing.
    Karasawa T, Kawashima A, Usui F, Kimura H, Shirasuna K, Inoue Y, Komada T, Kobayashi M, Mizushina Y, Sagara J, Takahashi M
    FEBS open bio 5 348-356 2015
  • Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.
    Nakagawa Y, Satoh A, Yabe S, Furusawa M, Tokushige N, Tezuka H, Mikami M, Iwata W, Shingyouchi A, Matsuzaka T, Kiwata S, Fujimoto Y, Shimizu H, Danno H, Yamamoto T, Ishii K, Karasawa T, Takeuchi Y, Iwasaki H, Shimada M, Kawakami Y, Urayama O, Sone H, Takekoshi K, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Suzuki H, Yamada N, Shimano H
    Endocrinology 155(12) 4706-4719 Dec. 2014
  • Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.
    Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
    Nanotoxicology 1-14 Sep. 2014
  • NLRP3 regulates neutrophil functions and contributes to hepatic ischemia-reperfusion injury independently of inflammasomes.
    Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, Tago K, Dezaki K, Nishimura S, Sagara J, Noda T, Iwakura Y, Tsutsui H, Taniguchi S, Yanagisawa K, Yada T, Yasuda Y, Takahashi M
    Journal of immunology (Baltimore, Md. : 1950) 192 4342-4351 May 2014
  • ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction.
    Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
    The American journal of pathology 184 1287-1298 May 2014
  • Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages.
    Hara K, Shirasuna K, Usui F, Karasawa T, Mizushina Y, Kimura H, Kawashima A, Ohkuchi A, Matsuyama S, Kimura K, Takahashi M
    PloS one 9(12) e113974 2014
Display all
Papers(paper)close
  • Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury.
    Komada T, Usui F, Kawashima A, Kimura H, Karasawa T, Inoue Y, Kobayashi M, Mizushina Y, Kasahara T, Taniguchi S, Muto S, Nagata D, Takahashi M
    Scientific reports 5 10901 Jun. 2015
  • RIP140 as a novel therapeutic target in the treatment of atherosclerosis.
    Karasawa T, Takahashi M
    Journal of molecular and cellular cardiology 81 136-138 Apr. 2015
  • NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β.
    Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M
    The Journal of biological chemistry 290(8) 5065-5077 Feb. 2015
  • Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.
    Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
    Arteriosclerosis, thrombosis, and vascular biology 35(1) 127-136 Jan. 2015
  • Oligomerized CARD16 promotes caspase-1 assembly and IL-1β processing.
    Karasawa T, Kawashima A, Usui F, Kimura H, Shirasuna K, Inoue Y, Komada T, Kobayashi M, Mizushina Y, Sagara J, Takahashi M
    FEBS open bio 5 348-356 2015
  • Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.
    Nakagawa Y, Satoh A, Yabe S, Furusawa M, Tokushige N, Tezuka H, Mikami M, Iwata W, Shingyouchi A, Matsuzaka T, Kiwata S, Fujimoto Y, Shimizu H, Danno H, Yamamoto T, Ishii K, Karasawa T, Takeuchi Y, Iwasaki H, Shimada M, Kawakami Y, Urayama O, Sone H, Takekoshi K, Kobayashi K, Yatoh S, Takahashi A, Yahagi N, Suzuki H, Yamada N, Shimano H
    Endocrinology 155(12) 4706-4719 Dec. 2014
  • Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.
    Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
    Nanotoxicology 1-14 Sep. 2014
  • NLRP3 regulates neutrophil functions and contributes to hepatic ischemia-reperfusion injury independently of inflammasomes.
    Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, Tago K, Dezaki K, Nishimura S, Sagara J, Noda T, Iwakura Y, Tsutsui H, Taniguchi S, Yanagisawa K, Yada T, Yasuda Y, Takahashi M
    Journal of immunology (Baltimore, Md. : 1950) 192 4342-4351 May 2014
  • ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction.
    Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
    The American journal of pathology 184 1287-1298 May 2014
  • Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages.
    Hara K, Shirasuna K, Usui F, Karasawa T, Mizushina Y, Kimura H, Kawashima A, Ohkuchi A, Matsuyama S, Kimura K, Takahashi M
    PloS one 9(12) e113974 2014
  • Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice.
    Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S, Takahashi M
    Biochemical and biophysical research communications 425 162-168 Aug. 2012
  • Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.
    Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H
    The Journal of biological chemistry 286 40835-40846 Nov. 2011
  • Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
    Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa Y, Iwasaki H, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N, Shimano H
    Arteriosclerosis, thrombosis, and vascular biology 31 1973-1979 Sep. 2011
  • Sterol regulatory element-binding protein-1 determines plasma remnant lipoproteins and accelerates atherosclerosis in low-density lipoprotein receptor-deficient mice.
    Karasawa T, Takahashi A, Saito R, Sekiya M, Igarashi M, Iwasaki H, Miyahara S, Koyasu S, Nakagawa Y, Ishii K, Matsuzaka T, Kobayashi K, Yahagi N, Takekoshi K, Sone H, Yatoh S, Suzuki H, Yamada N, Shimano H
    Arteriosclerosis, thrombosis, and vascular biology 31 1788-1795 Aug. 2011
  • Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.
    Matsuzaka T, Shimano H, Yahagi N, Kato T, Atsumi A, Yamamoto T, Inoue N, Ishikawa M, Okada S, Ishigaki N, Iwasaki H, Iwasaki Y, Karasawa T, Kumadaki S, Matsui T, Sekiya M, Ohashi K, Hasty AH, Nakagawa Y, Takahashi A, Suzuki H, Yatoh S, Sone H, Toyoshima H, Osuga J, Yamada N
    Nature medicine 13 1193-1202 Oct. 2007


Copyright c MEDIA FUSION Co.,Ltd. All rights reserved.