nagai ryozo

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Research Keywords

    transcription factor, KLF5, molecular biology

Research Areas

  • Clinical internal medicine / Circulatory organs internal medicine

Research Activities

Papers(paper)

  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
Display all
Papers(paper)close
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016
  • Rationale and Design of the Standard Versus Intensive Statin Therapy for Hypercholesterolemic Patients with Diabetic Retinopathy (EMPATHY) Study: a Randomized Controlled Trial
    Ueshima Kenji;Itoh Hiroshi;Kanazawa Nobuaki;Komuro Issei;Nagai Ryozo;Takeuchi Masahiro;Tsutomu Yamazaki;for the EMPATHY study group
    Journal of Atherosclerosis and Thrombosis 0(0) 2016

Papers(other)

  • c DNA doming of a myosin heavy chain isoform in embryonic smooth muscles and its expression during vascular development and in arteriosclerosis.
    J. Biol. Chem. 266 3763-3773 1991
  • Human smooth muscle myosin heavy chain isoform as molecular markers for vascular development and atherosclerosis.
    Circulation Res. 73 1000-1012 1993
  • Angiotensin II receptor antagonist TCV 116 regresses hypertensive left ventricular hypertrophy in vivo and inhibits intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro.
    Circulation 89 2204-2211 1994
  • Gene linkage analyses of Romano-Ward syndrome (RWS) in 13 Japanese families.
    Human Genetics 94 380-384 1994
  • Salt-sensitive hypertension in transgenic mice overexpressing sodium-proton exchanger.
    Circulation Res. 76 148-153 1995
  • Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
    Nature 390(6655) 45-51 1997
  • Mutations in the cardiac troponin 1 gene associated with hypertrophic cardiomyopathy
    Nature Genetics 16(4) 379-382 1997
  • Cardiac atrial myosin adenosine triphosphatase of animals and human : distinctive enzymatic properties compared with cardiac ventricular myosin.
    Circulation Research 45 522-527 1979
  • Radioimmunoassay of cardiac myosin light chain Ⅱ in the serum following experimental myocardial infarction.
    Biochem Biophys Res Comm 86(3) 683-688 1979
  • Serum cardiac myosin light chain Ⅱ in acute myocardial ingarction.
    Jpn Circ J 44 185-190 1980
Display all
Papers(other)close
  • c DNA doming of a myosin heavy chain isoform in embryonic smooth muscles and its expression during vascular development and in arteriosclerosis.
    J. Biol. Chem. 266 3763-3773 1991
  • Human smooth muscle myosin heavy chain isoform as molecular markers for vascular development and atherosclerosis.
    Circulation Res. 73 1000-1012 1993
  • Angiotensin II receptor antagonist TCV 116 regresses hypertensive left ventricular hypertrophy in vivo and inhibits intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro.
    Circulation 89 2204-2211 1994
  • Gene linkage analyses of Romano-Ward syndrome (RWS) in 13 Japanese families.
    Human Genetics 94 380-384 1994
  • Salt-sensitive hypertension in transgenic mice overexpressing sodium-proton exchanger.
    Circulation Res. 76 148-153 1995
  • Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
    Nature 390(6655) 45-51 1997
  • Mutations in the cardiac troponin 1 gene associated with hypertrophic cardiomyopathy
    Nature Genetics 16(4) 379-382 1997
  • Cardiac atrial myosin adenosine triphosphatase of animals and human : distinctive enzymatic properties compared with cardiac ventricular myosin.
    Circulation Research 45 522-527 1979
  • Radioimmunoassay of cardiac myosin light chain Ⅱ in the serum following experimental myocardial infarction.
    Biochem Biophys Res Comm 86(3) 683-688 1979
  • Serum cardiac myosin light chain Ⅱ in acute myocardial ingarction.
    Jpn Circ J 44 185-190 1980
  • Assessment of myocardial infarct size by serial changes in serum cardiac myosin light chain Ⅱ in dogs.
    Jpn Circ J 45(6) 661-666 1981
  • An extensive primary myocardial fibrosis in progressive systemic sclerosis.
    KAZUHIDE YAMAOKI, YOSHIO YAZAKI, HIROSHI MATSUNAGA, TERUNAO ASHIDA, RYOZO NAGAI, YASUYOSHI OHUCHI, SEIGO UEDA, YUZO MIYAKAWA, KINORI KOSAKA
    Jpn Circ J 46(11) 1159-1165 1982
  • Evaluation of methods for estimating infarct size by myosin light chain 2 : comparison with cardiac enzymes.
    Am J Physiol 245 413-419 1983
  • Initial dose of enalapril maleate (MK 421)in renovasulAr hypertension.
    Current Therapeutic Res 35 860-862 1984
  • Distribution of myosin isozymes in human atrial and ventricular myocardium : comparison in mormal and overloaded heart.
    Eur Heart J. 5 103-110 1984
  • Effects of steroid tratment on release of cardiac myosin light chain Ⅱ in acute myordial infarction in dogs.
    Am. J Cardiol 54 211-216 1984
  • Heterogeneity of myosin isozyme content of rabbit heart. .
    Circ Research 57 406-414 1985
  • Applications of anticardiac myosin monoclonal antibodies in the diagnosis of disease.
    Jpn Circ J 49(7) 733-739 1985
  • Quantitative relationship between left ventricular function and serum cardiac myosin light chain I levels after coronary reperfusion in patients with acute myocardial infarction.
    Circulation 76 1251-1261 1987
  • Myosin isozyme synthesis and mRNA leves in pressure-overloaded rabbit hearts.
    Circulation Research 60 692-699 1987
  • Characterization of a mammalian smooth muscle myosin heavy chain cDNA and its expression in various smooth muscle types.
    Proc. Natl. Acad. Sci. U. S. A. 85(4) 1047-1051 1988
  • Effeciency and capacity of protein synthesis are increased in pressure-overloaded rabbits.
    Am. J. Physiol. 255 325-328 1988
  • Developmentally regulated expression of vascular smooth muscle myosin heavy chain isoforms.
    J. Biol. Chem. 264 18272-18275 1989
  • Identification of two types smooth muscle mysin heavy chain isoforms by cDNA cloning and immunoblot analysis.
    J. Biol. Chem. 264 9734-9737 1989
  • Regulation of myocardial Ca+-ATPase and phospholamban mRNA expression in response to pressure overload and thyroid hormone.
    Proc. Natl. Sci. USA. 86(8) 2966-2970 1989
  • Quantification of myocardial infact size after coronary reperfusion by serum cardiac myosin light chain in coscious dogs.
    Circulation Research 65 684-694 1989
  • Infarct sizing after reperfusion by two-dimentional echocardiography and serum cardiac myosin light chain Ⅱ in conscious dogs.
    MITSUAKI ISOBE, RYOZO NAGAI, FUMIMARO TAKAKU, YOSHIO YAZAKI
    Jpn Circ J. 53(9) 1100-1107 1989
  • Endothelin : a potent vasoconstrictor associated with coronary vasospasm.
    Life Science 44(25) 1937-1943 1989
  • The possible role of endothelin-1 in the pathogenesis of coronary vasospasm.
    J. Cardiovasc Pharmacol 13 132-137 1989
  • Genetic and nongenetic control of myocardium calcium.
    Basic Res Cardiol 84 55-66 1989
  • Alteration of cardiac myosin isozymes after whole-body irradiation.
    Brit J Radiol. 62 189-191 1989
  • cDNA cloning of a myosin feavy chain isoform in embryonic smooth muscles and its expression during vascular development and in arteriosclerosis.
    J. Biol. Chem 266 3768-3773 1991
  • Identification of three types of PDGF-A chain gene transcripts in rabbit vascular smooth muscle and their regulated expression during vascular development and by angiotensin Ⅱ.
    Biochem Biophys Res Comm 184(2) 811-818 1992
  • Heterogeneity in smooth muscle cell population accumulating in the neointiomas and the media of poststenotic dilatation of the rabbit carotid artery.
    Biochem Biophys Res Comm 185(1) 459-464 1992
  • Developement of an immunoradiometric assay kit for ventricular myosin light chain I with monoclonal antibodies.
    Clin Chem 38 170-171 1992
  • Smooth muscle cell differentiation and atherogenesis. in「Intractable Vasculitis Syndrome」
    Hokkaido University Press 125-129 1993
  • Genus-specific polymerase chain reaction for the mycobacterial dnaJ gene and species-specific oligonucleotide probes.
    J. Clin. Microbiol 31 446-450 1993
  • Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in rat cardiac myocytes.
    J. Biol. Chem. 268 12069-12076 1993
  • Expression of intercellular adhesion molecule-1(ICAM-1)in rat heart with ischemia/reperfusion and of infarct size by treatment with antibodies against cell-adhesion molecules.
    Am. J. Pathol. 143 410-418 1993
  • Role of protein kinase system in the signal transduction of stretch-mediated protooncogene expression and hypertrophy of cardiac myocytes.
    Molecular and Cellular Biochemistry 119 11-16 1993
  • Tuberculous pericarditis presumably diagnosed by polymerase chain reaction analysis.
    Am. Heart J. 126 249-251 1993
  • Ductus arteriosus : advanced differentiation of smooth muscle cells demonstrated by myosin heavy chain isoform expression in rabbits.
    Circulation 88 1804-1810 1993
  • Right ventricular inflow obstruction due giant hematoma formed by chronic constricitive pericarditis.
    Internal Medicine 32(4) 346-349 1993
  • Nucleotide sequence comparison of the mycobacterial dna J gene and PCR-restriction fragment length polymorphism analysis for identification of mycobacterial species.
    Int J Syst Bacteriol 44 159-166 1994
  • Rapid growth of intracracranial aneurysms secondary to cardiac myxoma.
    Neurology 44 570-571 1994
  • Disruption of mouse endothelin-1 gene results in lethality and craniofacial anomaly in homozygotes and elevated blood pressure in heterxygotes.
    Nature 368 703-710 1994
  • Irreversible cardiomyopathy due to thyrotoxicosis.
    Cardiology 84 274-277 1994
  • Stenotic bicuspid aortic valve associated with a ventricular septal defect in an adult presenting with congestive heart failure : a rare observation.
    European Heart Journal 15 402-403 1994
  • Molecular aspects of the control of myocardial relaxation. in「Diastolic relaxation of the heart」
    Academic Publishers 25-32 1994
  • Isolation and characterzation of vascular endothelial cells derived from mice lacking endothelin-1.
    Biochem Biophys Res Comm 201(2) 538-545 1994
  • Role of Ca2+ and protein kainase C in shear stress-induced actin depolymerization and endothelin 1 gene expression.
    Circulation Research 75 630-636 1994
  • Involvement of the renin-angiotensin system in the development of left ventricular hypertrophy and dysfunction.
    Journal of Hypertension 12(Suppl9) S23-S27 1994
  • Immunosuppuession to cardiac allografts and soluble antigens anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies.
    J Immunol 153 5810-5818 1994
  • In vitro methods to study hypertrophy of cardiac cells.
    J Pharmacol Toxicol Methods 32(1) 19-23 1994
  • Human and murine cardiac-specific homebox-containing genes. in「Cardiac Development and Gene Regulation」ed Y Yazaki.
    Excerpta Medica. 35-40 1994
  • Diagnosis of aortic dissection by immunoassay for circulating smooth muscle myosin.
    Lancet 345 191-192 1995
  • Roles of vascular smooth muscles in atherosclerosis.
    Ryozo NAGAI, Nasanori AIKAWA, Makoto KURO-O, Yoshio YAZAKI
    Int Med 34(4) 279-281 1995
  • Activation of Na+-H+ antipoter(NHE-1)gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system
    J. Mol. Cell Cardiol 27 729-742 1995
  • Sarin poisoning in Tokyo subway.
    Lancet 345 980-981 1995
  • Development of an immunoassay for smooth muscle myosin heavy chain
    J Immunolog Method 185(1) 57-63 1995
  • Diversity and variability of smooth muscle phenotypes of renal arterioles as revealed by myosin isoform expression.
    Kidney Int 48 372-382 1995
  • Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes.
    J. Clin. Invest. 96 438-446 1995
  • Protein kinase cascade activated by mechanical stress in cardiocytes : possible involvement of angiotensin Ⅱ.
    Eur Heart J 16((supplC)) 8-11 1995
  • Angiotensin Ⅱ partly mediates mechanical stress-induced cardiac hypertrophy.
    Circ. Res. 77 258-265 1995
  • Glomerular expression of smooth-muscle myosin heavy chain isoforms in aminonucleoside nephrosis in rats.
    Clinical Science 86 45-52 1995
  • Difference of myosin heavy chain expression between mesangial cells and vascular smooth muscles.
    Jpn J Nephrol 37 428-435 1995
  • Effects of enalapril treatment on gene expression of smooth muscle myosin heavy chain isoforms in glomeruli of diabetic rats.
    Renal Physiol Biochem 18 183-190 1995
  • Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.
    J Clin Invest 96 293-300 1995
  • Phenotypic modulation of smooth muscle cells during progression of human atherosclerosis as determined by altered expression of myosin heavy chain isoforms.
    Ann New York Acad Sci. 748 578-585 1995
  • Immunocytochemical localization of 155 kDa myosin light chain kinase and myosin heavy chain in bovine brain.
    Brain Res 682(1/2) 212-214 1995
  • Primary pulmonary hypertension in association with human T-cell lymphotropic virus I in a hemophiliac.
    Annals of Int Med 123 394 1995
  • Assignment of cardiac homeobox gene CSX to human chromosome 5q34.
    Genomics. 27(1) 204-206 1995
  • Interaction of cardiac myocytes and non-myocytes in mechanical stress-induced hypertrophy.
    Herz 20 109-117 1995
  • Phenotypic changes of the mesangium in diabetic nephropathy.
    J Diabetes and complications 9 282-284 1995
  • Perforin-positive leukemic cell infiltration in the heart of a patient with T-cell prolymphocytic leukemia.
    Yoshinori SEKO, Miyuki AZUMA, Hideo YAGITA, Ko OKUMURA, Hisamaru HIRAI, Ryozo NAGAI, Yoshio YAZAKI
    Intern Med 34(8) 782-784 1995
  • Synthetic N omega-hydroxy-L-arginine causes endothelium-dependent vascular relaxation both in vitro and in vivo.
    J Smooth Muscle Res. 31 439-443 1995
  • Altered expression of smooth muscle and non-muscle myosin heavy chain isoforms in rejected hearts : a sensitive marker for acute rejection and graft coronary arteriosclerosis.
    Transplant Proc. 27 578 1995
  • Cytokine expression in cardiac allografts in mice with peripheral tolerance induced by anti-ICAM-1 and anti-LFA-1 monoclonal antibodies.
    Transplant Proc. 27 370-371 1995
  • Smooth muscle phenotypes in developing and atherosclerotic human arteries demonstrated by myosin expression.
    J Atheroscler Thromb 2 14-23 1995
  • Diversity of the synthetic-state smooth muscle cells proliferating in mechanically and hemodynamically injured rabbit arteries.
    Lab Invest 74 120-128 1996
  • Presence of contractile type smooth muscle cells in the endocardium Cardiology
    1996
  • Nonmuscle and smooth muscle myosin heavy chain expression in rejected cardiac allograft-a study in rat and monkey models.
    Circulation 94 1118-1124 1996
  • Preferential differentiation of P19 mouse embryonal carcinoma cells into smooth muscle cells ; use of retinoic acid and antisense against the central nervous system-specific POU transcription factor Brn-2.
    Circulation Res 78 395-404 1996
  • Tandem elements of CCTCCC are required for the cell-type-specific expression of the mouse smooth muscle myosin heavy chain gene(SM1/2)promoter.
    Circulatin Res 78 978-989 1996
  • Interleukin-8 as a sensitve marker of unstable coronary artery disease.
    Am J Cardiol 77 304-307 1996
  • Hypertensive glomerular damage as revealed by the expression of α-smooth muscle actin and non-muscle myosin.
    Kidney Int. 49(Supple) S-169-S172 1996
  • Beta-cell replication in insulin-induced remission of IDDM in BB/Woe//Yky rats.
    Diabetes Res 31 1-18 1996
  • Expression of a nonmuscle myosin heavy chain in glomerular cells differentiates various types of glomerular disease in rats.
    Kidney Int. 49 1231-1241 1996
  • A novel biochemical diagnostic method for aortic dissection-the results of a prospective study using an immunoassay of smooth muscle myosin heavy chain.
    Circulation 93 1244-1249 1996
  • Phenotypic modulation of the mesangium reflected by contractile proteins in Diabetes.
    Diabetes 45 488-495 1996
  • Amlodipine inhibits the development of right ventricular hypertrophy and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension.
    Res Comm in Mol Path Pharmacol 91 17-32 1996
  • Angiotensin converting enzyme polymorphism is associated with severity of coronary heart disease and serum lipids(total cholesterol and triglycerides levels)in Japanese patients.
    Coronary Artery Dis 7 371-375 1996
  • Interleukin-6 secreted from human myxoma reduces murine viral myocarditis.
    Life Sci 58(20) 1705-1712 1996
  • Relation between depressed cardiac response to exercise and autonomic nervous activity in mildly symptomatic patients with idiopathic dilated cardiomyopathy.
    Chest 109 925-932 1996
  • Modification of viral myocarditis in mice by interleukin-6.
    Circulation Res 78 848-856 1996
  • Effect of a Low-protein diet on expression of non-muscle type myosin heavy-chain isoforms in glomeruli of rats with puromycin aninomucleoside nephrosis.
    Nephrol Dial Transplant 11 1769-1774 1996
  • A selective type V phosphodiesterase inhibitor, E4021, protects the development of right ventricular overload and medial thickening of pulmonary arteries in a rat model of pulmonary hypertension.
    Life Sciences 59 371-377 1996
  • Sarcoplasmic reticulum genes are upregulated in mild cardiac hypertrophy but downregulated in severe cardiac hypertrophy induced by pressure overload.
    J Mol Cell Cardiol. 28 1583-1590 1996
  • Effects of enalapril on cardiac function, exercise capacity, and biochemical factors in patients with chronic heart failure.
    Current Therap Res 57 622-629 1996
  • Beneficial effect of amiloride, A Na+-H+ exchange blocker, in a murine model of dilated cardiomyopathy.
    Res Commun Mol Pathol Pharmacol. 92 201-210 1996
  • Sick sinus syndrome in association with malignant lymphoma
    Eur Heart J. 17 968 1996
  • Lack of inhibitory effect of dexamethasone on exhalation of nitric oxide by healthy humans.
    Kunio SATO, Hiroyuki SUMINO, Tetsuo SAKAMAKI, Hironosuke SAKAMOTO, Tetsuya NAKAMURA, Zenpei ONO, Ryozo NAGAI
    Intern Med 35(5) 356-361 1996
  • Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
    J Neurol Science 143 170-172 1996
  • Four novel KVLQT1 and four novel HERG mutations in familial long QT syndrome.
    Circulation 95 565-567 1997
  • The mechanism of catecholaminergic polymorphic ventricular tachycardia may be triggered activity due to delayed afterdepolarization.
    Eur Heart J 18 530-531 1997
  • Co-elevation of brain natriuretic peptide and proprotein-processing endoprotease furin after myocardial infarction in rats.
    FEBS letters 400(2) 177-182 1997
  • Redifferentiation of smooth muscle cells after coronary angioplasty determined via myosin heavy chain expression.
    Circulation 96 82-90 1997
  • Predictive value of left ventricular response to exercise in patients with dilated cardiomyopathy : assessment by radionuclide ventriculography.
    Angiology 48 497-502 1997
  • Adequacy of pacing rate during exercise in rate responsive ventricular pacing.
    PACE 20(PtI) 307-312 1997
  • Cardiac hypertrophy and expression of natriuretic peptides are enhanced by humoral factor(s) secondary to pressure overload : studies in the transplanted rat heart.
    Am J Physiol(Heart Circ Physiol) 273(1Pt2) H113-118 1997
  • Proliferation of smooth muscle cells in acute allograft vascular rejection.
    J Thorc Cardiovasc Surg 113 19-25 1997
  • Inflammatory cytokines cause coronary arteriosclerosis-like changes and alterations in the smooth-muscle phenotypes in pigs.
    J Cardivasc Pharmacol 29(2) 222-231 1997
  • Biochemical diagnosis of aortic dissection by elevated creatine kinase BB-isozyme levels.
    Lancet 350 784-785 1997
  • Stretch-induced hypertrophic growth of cardiocytes and processing of brain-type natriuretic peptide are controlled by proprotein-processing endoprotease furin.
    J Biol Chem 272(33) 20545-20554 1997
  • Chronic blockade of nitric oxide synthesis increases urinary endothelin-1 excretion.
    J Hypertension 15 373-381 1997
  • Decrease in myocardial polyamine concentration in rats with myocardial infarction.
    Life Sciences 60(19) 1643-1650 1997
  • Immunosuppressive drugs inhibit the production of interleukin-6 and interleukin-8 in cultured cardiac myxoma cells.
    Res Comm Mol Pathol Pharmacol 97 60-66 1997
  • Flow-mediated vasodilation of a conduit artery in relation to downstream perpheral tissue blood flow during reactive hyperemia in humans.
    Tetsuya Nakamura, Yuichiro Saito, Tatsuya Kato, Hiroyuki Sumino, Jin Hoshino, Zenpei Ono, Tetsuo Sakamaki, Ryozo Nagai
    Jpn Circ J 61(9) 772-780 1997
  • Hypertensive renal damage : modulation expression of smooth muscle myosin heavy chain isoforms.
    Nephrology 3 251-259 1997
  • Isolation of the embryonic form of smooth muscle myosin heavy chain(SMemb/NMHC-B)gene and characterization of its 5'-flanking region.
    Biochem Biophys Res Comm 239(2) 598-605 1997
  • Identification of mutations in the hepatocyte nuclear factor(HNF)-1α gene in Japanese subjects with IDDM.
    Diabetes 46 1643-1647 1997
  • Novel deletion on the short arm of chromosome 17 in a patient with multiple cardiac anomalies
    Keiko Kowase, Tetsuya Nakamura, Wataru Okumura, Eiichi Okamoto, Etsuo Yamaguchi, Hideki Sato, Masashi Arai, Susumu Imai, Akira Hasegawa, Ryozo Nagai
    Jpn Circ J 61(10) 882-885 1997
  • Transient hypertension due to adrenal hemorrhage in a patient with von Recklinghausen's disease.
    Intern Med 36(4) 289-292 1997
  • Mesangial expression of a non-muscle myosin heavy chain, SMemb is associated with glomerular sclerosis and a redictor of prognosis of IgA nephropathy
    Nephrology 3(Supple) A15-16 1997
  • Increased serum concentration of myosin heavy chain in aortic dissection : discussion of 2 cases.
    Z Kardiol 86 469-473 1997
  • Pulmonary expression of vascular endothelial growth factor and myosin isoforms in rats with congenital diaphragmatic hernia.
    J Pediatr Surg 32 391-394 1997
  • Ventilation/perfusion ratios and simultaneous dual-radionuclide single-photon emission tomography with krypton-81m and technetium-99m macroaggregated albumin
    Eur J Nucl Med 24 1237-1244 1997
  • Comparison of adenosine, dobutamine, and exercise radionuclide ventriculography in the detection of coronary artery disease.
    Cardiology 88 180-188 1997
  • Effect of amrinone on murine viral myocarditis.
    Res Commun Mol Pathol Pharmacol 95 57-66 1997
  • Change of plasma 1,5-anhydro-D-glucitol levels after the onset of diabetes in spontaneous diabetes prone BB/Wor/Tky rats.
    Horm Metab Res 29 9-11 1997
  • Depressed contractile response to exercise in diabetic patients in the absence of cardiovascular disease : relationship to adrenergic cardiac dysinnervation.
    Nucl Med Commun 18 761-770 1997
  • Expression of interleukin-6 in the ventricles and coronary arteries of patients with myocardial infarction.
    Res Commun Mol Pathol Pharmacol 97 3-12 1997
  • Reduced serum T3 level in a patient with nodular goiter and cardiac myxoma
    J Medicine 28 319-324 1997
  • Decreased basal production of nitric oxide in lung of patients with heart disease.
    Chest 113 317-322 1998
  • Combination of OK432 and human interfeon-α for treating viral induced diabetes mellitus in mice.
    Eur J Pharmacol 342(2/3) 297-302 1998
  • Inhibition of intimal hyperplasia after vein grafting by in vivo transfer of human senescent cell-derived inhibitor-1 gene.
    Gene Therapy 5 761-769 1998
  • Identification of the human klotho gene and its two transcripts encoding membrane and secreted Klotho portein.
    Biochem Biophys Res Comm 242(3) 626-630 1998
  • Effects of renal perfusion pressure on renal interstitial hydrostatic pressure and Na+ excretion : role of endothelium-derived nitric oxide.
    Nephron 78 104-111 1998
  • Effecient inhibition of the development of cardiac remodeling by a long-acting calcium antagonist amlodipine.
    Hypertension 31(Part1) 32-38 1998
  • Mesangial expression of a nonmuscle myosin heavy chain, SMemb, is associated with glomerular sclerosis and renal prognosis in IgA nephropathy.
    Nephron 78 284-289 1998
  • Elevated B-type natriuretic peptide levels after anthracycline administration.
    Am Heart J 136 362-363 1998
  • Mechanisms of transcriptional regulation of gene expression in smooth muscle cells.
    Circ Res 82 1238-1242 1998
  • Isolation and initial characterization of GBF ; a novel DNA-binding zinc finger protein binding to the GC-rich binding sites of the HIV-1 promoter.
    J Biochem 124 389-395 1998
  • Endothelin converting enzyme inhibitor protects development of right ventricular overload and medial +hickening of pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
    Life Sciences 63 137-143 1998
  • Sarcoplasmic reticulum genes are selectively down-regulated in cardiomyopathy produced by doxorubicin in rabbits.
    J Mol Cell Cardiol 30 243-254 1998
  • Hepatitis C virus infection and heart disease : a multicenter study in Japan
    Akira Matsumori, Naohiro Ohashi, Koji Hasegawa, Shigetake Sasayama, Tanenao Eto, Tsutomu Imaizumi, Tohru Izumi, Keishiro Kawamura, Masatoshi Kawana, Akinori Kimura, Akira Kitabatake, Masunori Matsuzaki, Ryozo Nagai, Hiromitsu Tanaka, Michiaki Hiroe, Masatsugu Hori, Hidetoshi Inoko, Yoshinori Seko, Morie Sekiguchi, Kunitada Shimotohno, Yasuro Sugishita, Nobuakira Takeda, Keiko Takihara, Masashi Tanaka, Takeshi Tokuhisa, Teruhiko Toyo-oka, Mitsuhiro Yokoyama, and Co-research workers
    Jpn Circ J 62(5) 389-391 1998
  • Klotho protein protects against endothelial dysfunction
    Biochem Biophys Res Comm 248(2) 324-329 1998
  • Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein.
    FEBS Letters 424(1/2) 6-10 1998
  • Improved oxygen utilization during mild exercise in heart failure.
    Jpn Circ J 62(10) 741-744 1998
  • A novel mechanism of HERG current suppression in LQT2 shift in voltage-dependence of HERG inactivation.
    Circ Res 83 415-422 1998
  • Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy.
    Circ Res. 82 430-437 1998
  • Technetium-99m Dimercaptosuccinic acid myocardial scintigraphy in a 74-year-old woman with congestive heart failure.
    J Cardiol 31 381-384 1998
  • Induction of virus-induced IDDM in virs resistant mice without lymphocyte maturation
    Life Sci 63(1) 33-40 1998
  • Genomic organization and mutational analysis of HERG, a gene responsible for familal ling QT syndrome.
    Human Genet 102(4) 435-439 1998
  • Antihypertensive agents prevent nephrosclerosis and left ventricular hypertrophy induced in rats by prolonged inhibition of nitric oxide synthesis
    Am J Hypertension 11 697-707 1998
  • Redistribution in thallium-201 myocardial imaging sson after successful coronary stenting : tomographic evaluation during coronary hyperemia induced by adenosine
    Hideki Nagaoka, Toshio Iizuka, Sachio Kubota, Masahiro Inoue, Etsuo Yamaguchi, Tadashi Suzuki, Ryozo Nagai
    Jpn Circ J 62(3) 160-166 1998
  • Type V phosphodiesterase inhibition modulates endogenous immunoreactivities of endothelin-1 and endothelial nitric oxide synthase in pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
    Res Exp Med 197 319-328 1998
  • Glomerular nonmuscle-type myosin heavy chain isoform gene expression in glomerulosclerosis.
    Nephron 79 317-321 1998
  • Prediction of transition to chronic atrial fibrillation in patients with paroxysmal atrial fibrillation.
    Circulation 98 1045 1998
  • Pre-chinical Cushing's syndrome with body wight loss and normal circadian rhythm of blood pressure.
    Int Med 37(6) 528-533 1998
  • Lipid lowering promotes accumulation of mature smooth muscle cells in atheroma of hypercholesterolemic rabbits.
    Circ Res 83 1015-1026 1998
  • Downregulation of the klotho gene in the kidney under sustained circulatory stress in rats
    Biochem Biophys Res Comm 249(3) 865-871 1998
  • Molecular cloning of rat klotho cDNA : markedly decreased expression of klotho by acute inflammatory stress.
    Biochem Biophys Res Comm 251(3) 920-925 1998
  • Ventricular fibrillation triggered by a ruptured sinus of Valsalva aneurysm
    Heart 80 203-204 1998
  • Impaired expression of atrial natriuretic peptide in diabetic rats with myocardial infarction
    Res Comm Mol Pathol Pharm 100 327-338 1998
  • Immunohistochemical studies on expression of human vascular smooth muscle myosin heavy chain isoforms in normal mammary glands, benign mammary disorders and mammary carcinomas.
    Pathol Int 48 433-439 1998
  • Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome.
    Human Genet 103(3) 290-294 1998
  • ETA receptor antagonist ameliorates nephrosclerosis and left ventricular hypertrophy induced in rat by prolonged inhibition of nitric oxide synthesis
    Tetsuya Nakamura, Toshiaki Kurashina, Yuichiro Saito, Hiroyuki Sumino, Nobuhiro Akuzawa, Hiroki Aizawa, Hironosuke Sakamoto, Zenpei Ono, Ryozo Nagai
    Hypertension Res 21(4) 251-257 1998
  • Bilateral coronary ostial stenosis and aortic regurgitation due to syphilitic aortitis.
    Hiroki AIZAWA, Akira HASEGAWA, Masashi ARAI, Fumio NAGANUMA, Masako HATORI, Tsugiyasu KANDA, Tadashi SUZUKI, Kazuhiko MURATA, Yasushi SATOH, Susumu ISHIKAWA, YASUO MORISHITA, Ryozo NAGAI
    Intern Med 37(1) 56-59 1998
  • Lecithinized superoxide dismutase induces vasodilation ; evidence of direct contribution of superoxide anions to modulating vascular tone.
    Life Sciences 64 PL65-PL70 1998
  • Detection of left ventricular enlargement by electrocardiography
    J Med 29 231-236 1998
  • Heat stress aggravates viral myocarditis in mice.
    Life Sciences 64(2) 93-101 1999
  • Antagonism of ANGII type 1 receptors protects the endothelial function during the early stage of renal hypertension in rats.
    Am J Physiol 275(6Pt2) R1950-1957 1998
  • Impaired expression of brain natriuretic peptide gene in diabetic rats with myocardial infarction.
    Exp Clin Endocrinol Diabetes 106 484-488 1998
  • White coat effect induced by therapist's presence during speech therapy for stroke rehabilitation : a single case study.
    Arch Phys Med Rehab 80 470-472 1999
  • Loculated pericardial effusion due to congestive heart failure : an unusual case of vanishing tumor.
    Angiology 50 683-687 1999
  • Sudden death with malignant hemangioendothelioma originating in the pericardium : a case report.
    Angiology 50 607-611 1999
  • Somatostatin analogue octreotide inhibits in vitro outgrowth of smooth muscle cells from canine coronary and carotid atherosclerotic plaque tissues
    Res Comm in Molecular Pathol Pharmacol 101 25-34 1998
  • Production of a radioactive endovascular stent by implantation of 133Xe ions.
    Applied Radiation and Isotopes 51(2) 197-202 1999
  • Tumor necrosis factor-α decreases the phosphorylation levels of phospholamban and troponin (]G0001[) in spontaneously beating rat neonatal cardiac myocytes
    J Mol Cell Cardiol 31 261-273 1999
  • The time from anaerobic threshold(AT)to respiratory compensation point reflects the rate of aerobic and anaerobic metabolism after the AT in chronic heart failure patients.
    Jpn Circ J 63(4) 274-277 1999
  • A Na+-H+ exchange inhibitor(SM-20550) protects from microvascular deterioration and myocardial injury after reperfusion
    Eur J Pharmacol 374(3) 355-366 1999
  • BTEB2, a Kruppel-like transcription factor, regulates expression of the SMemb/non-muscle myosin heavy chain B(SMemb/NMHC-B)gene
    Circ Res 85 182-191 1999
  • Effect of probucol on smooth muscle cell proliferation and dedifferentiation after vascular injury in rabbits : possible role of PDGF.
    Cardiovasc Drugs Ther. 12 251-260 1998
  • Cardiac sympathetic activity estimated by 123(]G0001[)-MIBG myocardial imaging in patients with dilated cardiomyopathy after beta-blocker or angiotensin-converting enzyme inhibitor therapy.
    J Nucl Med 40 217-223 1999
  • Predicting functional recovery after revascularization in coronary artery disease using Fluorine-18 FDG and Iodine-123 BMIPP SPECT
    Chest 117 65-72
  • Serum level of vascular endothelial growth factor is decreased by hormone replacement therapy in postmenopausal women without hypercholesterolemia
    Atherosclerosis 148 189-195 2000
  • Biopsy-proven cardiomyophaty in heterozygous Fabry's disease
    Norimichi Koitabashi, Toshihiro Utsugi, Ryotaro Seki, Eiichi Okamoto, Yoshichika Sando, Yoshiaki Kaneko, Ryozo Nagai
    Jpn Circ J 63(7) 572-575 1999
  • Angiotensin II and mechanical stretch induce production of tumor necrosis factor in cardiac fibroblasts
    Am J Physiol 276 H1968-H1976 1999
  • Disruption of the klotho gene causes pulmonary emphysema in mice : defect in maintenace of pulmonary integrity during postnatal life
    Am J Resp Cell Mol Biol 22 26-33 2000
  • Reduced production of nitric oxide during haemodialysis
    J Human Hypertension 13 437-442 1999
  • Polymorphisms in the SOD2 and HLA-DRB1 genes are associated with nonfamilial idiopathic dilated cardiomyopathy in Japanese
    Biochem Biophys Res Commun 261(2) 332-339 1999
  • Dietary salt loading increases nitric oxide synthesis in transgenic mice overexpressing sodium-proton exchanger.
    Jun-ichi Kiraku, Tetsuya Nakamura, Takao Sugiyama, Naoyuki Takahashi, Makoto Kuro-o, Jun Fujii, Ryozo Nagai
    Jpn J Pharmacol 80(2) 181-183 1999
  • Endothelin-1 induces expression of fetal genes througth the interleukin-6 family of cytokines in cardiac myocytes
    FEBS Lett 456(1) 103-107 1999
  • Hypoxia induces activation and subcellular translocation of focal adhesion kinase(p125(FAK))in cultured rat cardiac myocytes.
    Biochem Biophys Res Commun 262(1) 290-296 1999
  • Induction of smooth muscle cells in the fibrous capsule of human hepatocellular carcinoma but not in the septa of hepatic cirrhosis.
    Virchows Arch 434 413-422 1999
  • Nuclear hypersegmentation precedes the increase in blood eosinophils in acute eosinophilic pneumonia
    Toshitaka MAENO, Yuri MAENO, Yoshichika SANDO, Takashi TAKAHASHI, Hiroshi YARITA, Masaaki TSUKAGOSHI, Tatsuo SUGA, Masahiko KURABAYASHI, Ryozo NAGAI
    Internal Med 39(2) 157-159 2000
  • Pleural amyloidosis in a patient with intractable pleural effusion effusion and multiple myeloma.
    Respirology 5 79-80 2000
  • Transcriptional activation of the zinc finger transcription factor BTEB2 gene by Egr-1 through mitogen-activated protein kinase pathways in vascular smooth muscle cells
    Circ Res 85 787-795 1999
  • PPARγmediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
    mol Cell 4 597-609 1999
  • MAPR superfamily plays an important role in daunomycin-induced apoptosis of cardiac myocytes
    Circulation 100 2100-2107 1999
  • Calcineurin plays a critical role in pressure overload-induced cardiac hypertrophy
    Circulation 100 2449-2454 1999
  • Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca2+-ATPase gene transcription
    Circ Res 86 8-14 2000
  • Endothelin and neural crest develpment.
    Cell Mol Biol(Noisy-Le-Grand) 45 639-651 1999
  • A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids
    J. Biol Chem 274(50) 35840-35844 1999
  • Sphingosylphosphorylcholine induces a hypertrophic growth response through the mitogen-activated protein kinase signaling cascade in rat neonatal cardiac myocytes
    Circ Res 85 1000-1008 1999
  • Embryonic smooth muscle myosin heavy chain SMemb is expressed in pressure-overloaded cardiac fibroblasts.
    Jpn Heart J 40(6) 803-818 1999
  • An interleukin-6-producing cardiac myxoma associated with mediastinal lymphadenopathy.
    Cardiology 92(4) 275-277 1999
  • Voltage-shift of the current activation in HERG S4 mutation(R534C)in LQT2
    Cardiovasc Res 44 283-293 1999
  • Hypoxia Induces Transcription of the Plasminogen Activator Inhibitor-1 Gene Through Genistein-Sensitive Tyrosine Kinase Pathways in Vascular Endothelial Cells.
    Arterioscler Thromb Vasc Biol 20(4) 1155-1161 2000
  • Inducible expression of basic transcription element-binding protein 2 in proliferating smooth muscle cells at the vascular anastomotic stricture.
    J Thorac Cardiovasc Surg 119(5) 983-989 2000
  • Increased severity of viral myocarditis in mice lacking lymphocyte maturation
    Int J Cardiol 68 13-22 1999
  • Steroid therapy is effective in a young patient with an inflammatory abdominal aortic aneurysm
    J Med 30 67-74 1999
  • Hormone replacement therapy in postmenopausal women with essential hypertension increases circulating plasma levels of bradykinin
    Am J Hypert 12 1044-1047 1999
  • C-reactive protein in dilated cardiomyopathy
    Cardiology 91 215-219 1999
  • Molecular cloning of rabbit CARP cDNA and its regulated expression in adriamycin-cardiomyopathy
    Biochim Biophys Acta 1447 318-324 1999
  • Disruption of ET-1 gene enhances pulmonary response to methacholine via functional mechanism in knockout mice
    J Appl Physiol 87 2020-2024 1999
  • Increased leukotriene A(4)hydrolase expression in the heart of angiotensin (]G0002[)-induced hypertensive rat
    FEBS Lett 463(1/2) 155-159 1999
  • Regulation of interaction of the acetyltransferase region of p300 and the DNA-binding domain of Sp1 on and through DNA binding
    Genes Cells 5(1) 29-41 2000
  • Renal Artery Stenosis Associated with Epidermal Nevus Syndrome
    Nephron 84(1) 67-70 2000
  • Prediction of functional recovery after revascularization in coronary artery disease using(18)F-FDG and(123)I-BMIPP SPECT
    Chest 117(1) 65-72 2000
  • Insulin effect during embryogenesis determines fetal growth : a possible molecular link between birth weight and susceptibility to type 2 diabetes
    Diabetes 49(1) 82-86 2000
  • Transcription of the SERCA2 gene is decreased in pressure-overloaded hearts : a study using in vivo direct gene transfer into living myocardium.
    J Mol Cell Cerdiol 31(12) 2167-2174 1999
  • Biochemical diagnosis of aortic dissection : from bench to bedside
    Jpn Heart J 40(5) 527-534 1999
  • Cardiac ankyrin repeat protein is a novel marker of cardiac hypertrophy : Role of M-CAT element within the promoter.
    Hypertension 36(1) 48-53 2000
  • Sodium/hydrogen ion exchange inhibitor ameliorates ischaemia-reperfusion injuries in the rat hind limb
    Int Angiol 18 320-326 1999
  • Inducible expression of manganese superoxide dismutase by phorbol 12-myristate 13-acetate is mediated by Sp1 in endothelial cells
    Arterioscler Thromb Vasc Biol 20 392-401 2000
  • Zinc finger transcription factor Egr-1 activates Flt-1 gene expression in THP-1 cells on induction for macrophage differentiation
    Arterioscler Thromb Vasc Biol 20 377-384 2000
  • Lipopolysaccharide augments expression and secretion of vascular endothelial growth factor in rat ventricular myocytes.
    Biochem Biophys Res Commun 268(2) 657-662 2000
  • Transcriptional regulation of smooth muscle phenotypic modulation.
    Jpn J Pharmacol 82(Suppl (]G0001[)) 25 2000
  • Simple and practical sandwich-type enzyme immunoassay for human oxidatively modified low density lipoprotein using anti-oxidized phosphatidylcholine monoclonal antibody and anti-human apolipoprotein-B antibody.
    Clin Chem 33(4) 243-253 2000
  • Increases in intracellular calcium of arterial smooth muscle cells in transgenic mice overexpressing Na+/H+ exchanger.
    J Cardiovasc Pharmacol 35(3) 511-513 2000
  • Cardiac interleukin-6 in ischemic myocardium.
    Circulation 101(8) E86 2000
  • Heme oxygenase-1 is upregulated in the kidney of angiotensin Ⅱ-induced hypertensive rats : possible role in renoprotection.
    Hypertension 35(3) 800-806 2000
  • Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging.
    Metabolism 49 1118-1123 2000
  • Pressurization facilitates adenovirus-mediated gene transfer into vein graft.
    FEBS Lett 470(3) 370-374 2000
  • Inducible expression of BTEB2, a member of zinc-finger family of transcription factors, in cardiac allograft vascular disease.
    Transplantation 70 1653-1656 2000
  • Fibroblast Growth Factor Plays a Critical Role in SM22alpha Expression During Xenopus Embryogenesis.
    Arterioscler Thromb Vasc Biol 20(4) 907-914 2000
  • Renovascular Hypertension Observed in a Patient with Antiphospholipid-Antibody Syndrome.
    Kenichi Aizawa, Tetsuya Nakamura, Hiroyuki Sumino, Yuichiro Saito, Jin Hoshino, Toshiaki Kurashina, Hisao Kumakura, Shuichi Ichikawa, Ryozo Nagai
    Jpn Circ J 64(7) 541-543 2000
  • Inducible expression of BTEB2, a member of zinc-finger family of transcription factors, in cardiac allograft arteriosclerosis.
    Transplant Proc 32 2032-2033 2000
  • Up-regulation of natriuretic peptides in the ventricle of Csx/Nkx2-5 transgenic mice.
    Biochem Biophys Res Commun 270(3) 1074-1079 2000
  • Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia.
    J Lipid Res 41(8) 1199-1204 2000
  • Endothelin-1 is a potent activator of nonselective cation currents in human bronchial smooth muscle cells.
    Am J Respir Cell Mol Biol 23(2) 213-221 2000
  • Evidence for association between paraoxonase gene polymorphisms and atherosclerotic diseases.
    Atherosclerosis 149 435-442 2000
  • Serum levels of vascular endothelial growth factor and transforming growth factor-beta1 in patients with atrial fibrillation undergoing defibrillation therapy.
    Jpn Heart J 41(1) 27-32 2000
  • C-reactive protein as a prognostic marker in lymphocytic myocarditis.
    Jpn Heart J 41(1) 41-47 2000
  • Therapy with the nonpeptide endothelin receptor antagonist 97-139 in a murine model of congestive heart failure : reduction of cardiac mass and myofiber hypertrophy.
    Jpn Heart J 41(1) 79-85 2000
  • Ca2+/Calmodulin-dependent kinase Ⅱ and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
    J Biol Chem 275(20) 15239-15245 2000
  • Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature.
    Circulation 101(19) 2309-2316 2000
  • ADAMTS-1 : a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function.
    J Clin Invest 105(10) 1345-1352 2000
  • Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy.
    J Clin Invest 105(10) 1437-1445 2000
  • Twenty single nucleotide polymorphisms(SNPs)and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population.
    J Hum Genet 45(3) 182-183 2000
  • Intracoronary serum smooth muscle myosin heavy chain levels following PTCA may predict restenosis.
    Yasuhiro TSUCHIO, Shigeto NAITO, Akihiko NOGAMI, Hiroshi HOSHIZAKI, Shigeru OSHIMA, Koichi TANIGUCHI, Hirohisa KATOH, Toru SUZUKI, Masahiko KURABAYASHI, Akira HASEGAWA, Ryozo NAGAI
    Jpn Heart J 41(2) 131-140 2000
  • Screening for cardiac dysfunction in asymptomatic patients by measuring B-type natriuretic peptide levels.
    Toru SUZUKI, Kazuhide YAMAOKI, Osamu NAKAJIMA, Tsutomu YAMAZAKI, Yoshiharu YAMADA, Hisashi AKIOKA, Yoshio YAZAKI, Ryozo NAGAI
    Jpn Heart J 41(2) 205-214 2000
  • Coronary microangiopathy in type 2 diabetic patients : relation to glycemic control, sex, and microvascular angina rather than to coronary artery disease.
    J Nucl Med 41(6) 978-985 2000
  • Regulated expression of the BTEB2 transcription factor in smooth muscle cells : analysis of developmental and pathological expression profiles show implications as a predictive factor for restenosis.
    Circulation 102 2528-2534 2000
  • Transcriptional regulation of human cardiac homeobox gene CSX1.
    Biochem Biophys Res Commun 272(3) 749-757 2000
  • Oral administration of branched chain amino acids improves virus-induced glucoseintolerance in mice.
    Eur J Pharmacol 398(3) 409-414 2000
  • Transcriptional regulation of smooth muscle phenotypic modulation.
    Ann N Y Acad Sci 902 214-222,discussion222-223 2000
  • Expression of genes encoding vascular endothelial growth factor and its Flk-1 receptor in the chick embryonic heart.
    J Mol Cell Cardiol 32(6) 1039-1051 2000
  • Oozing from the pericardium as an etiology of cardiac tamponade associated with screw-in atrial leads.
    PACE 24 381-383 2001
  • Role of insulin resistance in heart and skeletal muscle F-18 fluorodeoxyglucose uptake in patients with non-insulin-dependent diabetes mellitus.
    J Nucl Cardiol 7(3) 242-248 2000
  • Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases.
    Cell Mol Life Sci 57(5) 738-746 2000
  • Cloning of murine glycosyl phosphatidylinositol anchor attachment protein, GPAA1.
    Am J Physiol Cell Physiol 279(1) C205-C212 2000
  • Doxorubicin Represses CARP Gene Transcription Through the Generation of Oxidative Stress in Neonatal Rat Cardiac Myocytes : Possible Role of Serine/Threonine Kinase-dependent Pathways.
    J Mol Cell Cardiol 32(8) 1401-1414 2000
  • Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism.
    Hypertension 36(1) 83-88 2000
  • Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation.
    Genes Cells 5(6) 499-513 2000
  • Homocysteine as a risk factor for restenosis after coronary angioplasty.
    Thromb Haemost 84(1) 27-31 2000
  • Genetic coronary risk factors in conventionally low-risk patients.
    Thromb Haemost 84(1) 137 2000
  • Application of Hydrostatic Pressure Facilitates ex Vivo Adenovirus Gene Transfer into Rabbit Aortas.
    Biochem Biophys Res Commun 274(2) 422-426 2000
  • Sterol regulatory element-binding-1 protein is regulated by glucose at the transcriptional level.
    J Biol Chem 275(40) 31069-31077 2000
  • Heme oxygenase-1 is upregulated in the rat heart in response to chronic administration of angiotensin Ⅱ.
    Am J Physiol Heart Circ Physiol 279(2) H672-H678 2000
  • Serum levels of smooth muscle heavy-chain myosin in patients with ectopic pregnancy.
    Ann Emerg Med 36(2) 101-107 2000
  • Bile acids increase intracellular Ca(2+)concentration and nitric oxide production in vascular endothelial cells.
    Br J Pharmacol 130(7) 1457-1467 2000
  • Beta-adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes.
    J Biol Chem. 275(44) 34528-34533 2000
  • The clinical significance of reversed flow in the main pulmonary artery detected by doppler color flow imaging.
    Chest 118(2) 336-341 2000
  • Expression of the transcriptional factor Egr-1/BTEB2 in cardiac xenograft vascular remodeling.
    Transplant Proc 32(5) 1089-1091 2000
  • Role of endothelin-1 in stress response in the central nervous system.
    Am J Physiol Regul Integr Comp Physiol 279(2) R515-R521 2000
  • Constitutive tyrosine phosphorylation of ErbB-2 via Jak2 by autocrine secretion of prolactin in human breast cancer.
    J Biol Chem. 275(43) 33937-33944 2000
  • Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease.
    J Biol Chem. 275(45) 35291-35296 2000
  • Unclassified connective tissue disease presenting as cardiac tamponade : a case report.
    Yumiko Oishi, Masashi Arai, Jun-ichi Kiraku, Hiroshi Doi, Tsuyoshi Uchiyama, Akira Hasegawa, Masahiko Kurabayashi, Ryozo Nagai
    Jpn Circ J 64(8) 619-622 2000
  • Lecithinized copper, zinc-superoxide dismutase ameliorates prolonged hypoxia-induced injury of cardiomyocytes.
    Free Radic Biol Med 29(1) 34-41 2000
  • Restricted usage of T-cell receptor Vgamma-Vdelta genes and expression of costimulatory molecules in Takayasu's arteritis.
    Int J Cardiol 75(Suppl 1) S77-S83 2000
  • Augmented responses of angiotensin Ⅰ and Ⅱ in patients with ischemic heart disease : relation to left ventricular function.
    Sekiguchi Kenichi, Kanda Tsugiyasu, Ono Zenpei, Tanaka Toru, Yokoyama Tomoyuki, Aihara Yasushi, Toyama Takuji, Sakamaki Tetsuo, Kobayashi Isao, Kurabayashi Masahiko, Nagai Ryozo
    Jpn Heart I 41(3) 269-278 2000
  • Effects of antihypertensive therapy on blood pressure and left ventricular hypertrophy in patients with severe hypertension.
    Sumino Hiroyuki, Nakamura Tetsuya, Kanda Tsugiyasu, Sakamaki Tetsuo, Sato Kunio, Saito Yuichiro, Hoshino Jin, Kurashina Toshiaki, Ono Zenpei, Takahashi Takashi, Ichikawa Shuichi, Kurabayashi Masahiko, Nagai Ryozo
    Jpn Heart J 41(3) 339-348 2000
  • Characterization of S818L mutation in HERG C-terminus in LQT2 Modification of activation gating properties
    FEBS Lett 481(2) 197-203 2000
  • Diagnostic implications of elevated levels of smooth-muscle myosin heavy-chain protein in acute dissection : the smooth myosin heavy chain study.
    Ann Intern Med 133 537-541 2000
  • In vivo kloth gene delivery protects against endothelial dysfunction in multiple risk factor syndrome.
    Biochem Biophys Res Commun 276(2) 767-772 2000
  • Circulating oxidized low density lipoprotein levels : a biochemical risk marker for coronary heart disease.
    Arterioscler Thromb Vase Biol 2 20 2243-2247 2000
  • Calcineurin inhibitor attenuates the development and induces the regression of cardiac hypertrophy in rats with salt-sensitive hypertension
    Circulation 102 1996-2004 2000
  • Induction of VEGF gene transcription by 1L-1β is mediated through stress-activated MAP Kinases and Sp1 sites in cardiac myocytes
    J Mol Cell Cardiol 32 1955-1967 2000
  • A mouse model of vascular injury that induces rapid of medial cell apoptosis followed by reproducible neointimal hyperplasia
    J Mol Cell Cardiol 32 2097-2104 2000
  • Evalution of the heart with magnetic resonance imaging
    Jun-ichi Suzuki, Ryozo Nagai, Jun-ichi Nishikawa, Kuni Ohotomo, Teruhiko Toyo-oka, Masao Omata
    Jap Heart J 41(4) 417-424 2000
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    Diabetes 49 1880-1889 2000
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    Mol Cell Biochem 212(1/2) 177-182 2000
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    Jap Heart J 41(6) 713-721 2000
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    Jap Heart J 41(6) 767-772 2000
  • Oozing from the pericardium as an etiology of cardiac tamponade associated with screw-in atrial leads.
    Pacing Clin Electrophysiol 24 381-383 2001
  • Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury
    Circulation 103 133-139 2001
  • Transforming growth factor-β/Smads signaling induces transcription of the cell type-restricted ankyrin repeat protein CARP gene through CAGA motif in vascular smooth muscles cells.
    Circulation Res 88 30-36 2001
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    Circulation Res 88 52-58 2001
  • Endogenous PPARr Mediates Anti-inflammatory Activity in murine Ischemia-Reperfusion injury
    Gastroenterology 120 460-469 2001
  • The role of glalectin-3 in endocytosis of advanced glycation end products and modified low density lipoprotein
    Biochem Biophys Res Commun 280(4) 1183-1188 2001
  • Different effects of angiotensin Ⅱ and catecholamine on renal cell apoptosis and proliferation in rats
    Kidney Int. 59 645-653 2001
  • Correlation of genetic etiology with response to β-adrenergic blockade among symptomatic patients with familial long-QT syndrome
    J Hum Genet 46(1) 38-40 2001
  • Immunoscintigraphy of aortic dissection with 99mTc-labeled murine anti-smooth muscle myosin monoclonal antibody in rats
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    Biochem Biophys Res Commun 281(4) 1057-1062 2001
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  • Correlation of genetic etiology with response to β-adrenergic blockade among symptomatic patients with familial long-QT syndrome
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    J Cell Biol. 153(4) 687-698 2001
  • Vasular smooth muscle cell phenotypes in primary pulmonary hypertensin.
    Eur Respir J 17 316-320
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  • Left ventricular relaxation abnormality is detextable by analysis of the relaxation time constant in patients with atrial fibrillation
    Kazumasa Harada, Yasuyuki Sugishita, Tatsuya Shimizu, Atsushi Yao, Hiroshi Matsui, Osami Kohmoto, Takashi Serizawa, Ryozo Nagai, Toshiyuki Takahashi
    Japanese Circulation Journal 65(7) 610-616 2001
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    J Am Soc Echocardiogr 14 650-653 2001
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    Hypertens Res 24(4) 385-394 2001
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    Circulation 104 102-108 2001
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    Nature genetics 28(3) 276-280 2001
  • Calcineurin plays a critical rale in the development of pressure overload-induced cardiac hypertrophy
    Circulation 104 97-101 2001
  • The elevated proinsulin-to-insulin ratio is associated with oxidative stress in Down's syndrome
    Diabetologia 44 788-789 2001
  • Beta-blocker therapy improved symptoms and exercise capacity in a patient with dynamic intra-right ventricular obstruction : an atypical form of double-chambered right ventricle
    Journal of the American Society of Echocardiography 14 650-653 2001
  • Combined effect of retinoic acid basic FGF on PAI-1 gene expression in vascular smooth muscle cells
    Cardiovascular Research 51 151-159 2001
  • Traumatic tricuspid insufficiency
    Echocardiography 18 303-304 2001
  • Enhancement of Endothelial Nitric Oxide Production by Chenodeoxycholic Acids in Patients with Hepatobiliary Disease. "jointly worked"
    Jpn Heart J 42, 339-353 2001
  • The fat-derived horm one adiponectin reverses insulin resistance associated with both lipoatrophy and obesity "jointly worked"
    Nat Med 7, 941-946 2001
  • Hypertrophic Cardimyopathy with Midventricular Obstruction and Apical Aneurysm -A Case Report- "jointly worked"
    Jpn Circ J 65, 915-919 2001
  • Troglitazone Improves Endothelial Function and Augments Renal klotho mRNA Expression in Otsuka Long-Evans Tokushima Fatty (OLETF) Rats with Multiple Atherogenic Risk Factors. "jointly worked"
    Hyperteinsion Res 24, 705-709 2001
  • Lecithinized copper, zinc-superoxide dismutase ameliorates ischemia-induced myocardial damage. "jointly worked"
    Life Sciences 69, 935-944 2001
  • Lecithinized copper, zinc-superoxide dismutase ameliorates prolonged hypoxia-induced injury of cardiomyocytes. "jointly worked"
    Free Radical Biology & Medicine 29, 34-41 2001
  • Ets-1 is involved in transcriptional regulation of the chick inducible nitric oxide synthase gene in embryonic ventricular myocytes. "jointly worked"
    Molecular and Cellular Biochemistry 226, 57-65 2001
  • Acute and Chronic Smooth Muscle Cell Apoptosis After Mechanical Vascular Injury Can Occur Independently of the Fas-Death Pathway. "jointly worked"
    Arterioscler Thromb Vasc Biol 21, 1733-1737 2001
  • A Novel Myocyte-specific Gene Midori Promotes the Differentiation of P19CL6 Cells into Cardiomyocytes. "jointly worked"
    J Biol Chem 276, 35978-35989 2001
  • Measurement of plasma brain natriuretic peptide level as a guide for cardiac overload. "jointly worked"
    Cardiovascular Res. 51, 585-591 2001
  • Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia. "jointly worked"
    FASEB J 15, 2530-2532 2001
  • Urotensin Ⅱ induces hypertrophic responses in cultured cardiomyocytes from neonatal rats. "jointly worked"
    FEBS Letters 508, 57-60 2001
  • Evidence for the Physiological and Pathological Roles of Adrenomedullin from Genetic Engineering in Mice. "jointly worked"
    in "ATHEROSCLEROSIS VI" ed by Numano F, Gimbrone MA, Jr, pp 26-34, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, Volume 947 (The sixth Saratoga international conference, 2001) 947, 26-34 2001
  • Phenotypic Modulation of Vascular Smooth Muscle Cells-Dissection of Transcriptional Regulatory Mechanisms. "jointly worked"
    in "ATHEROSCLEROSIS VI" ed by Numano F, Gimbrone MA, Jr, pp 56-67, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, Volume 947 (The sixth Saratoga international conference, 2001) 947, 56-67 2001
  • Molecular Mechanisms of Morning Onset of Myocardial Infarction. "jointly worked"
    in "ATHEROSCLEROSIS VI" ed by Numano F, Gimbrone MA, Jr, pp 398-402, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, Volume 947 (The sixth Saratoga international conference, 2001) 947, 398-402 2001
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    Annals of emergency medicine 38, 628-632 2001
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    J Clin Invest 108, 1001-1013 2001
  • Retinoids induce the PAI-1 gene expression through tyrosine kinase-dependent pathways in vascular smooth muscle cells "jointly worked"
    Journal of Cardiovascular Pharmacology 39, 503-512 2001
  • Elevated Sympathetic Nervous Activity in Mice Deficient in α CGRP. "jointly worked"
    Circ Res. 89, 983-990 2001
  • Vasuclar Abnormalities and Elevated Blood Pressure in Mice Lacking Adrenomedullin Gene. "jointly worked"
    Circulation 104, 1964-1971 2001
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    Am J Physiol Heart Circ Physiol 281, H1442-H1446 2001
  • Lecithinized Cu, Zn-Superoxide Dismutase Limits the Infarct Size Following Ischemia-Reperfusion Injury in Rat Hearts in Vivo. "jointly worked"
    Biochem Biophys Res Commun 285, 1220-1225 2001
  • Severe Hypercholesterolemia, Hypertriglyceridemia, and Atherosclerosis in Mice Lacking Both Leptin and the Low Density Lipoprotein Receptor. "jointly worked"
    J Biol Chem 276, 37402-37408 2001
  • Increased Expression of the Sterol Regulatory Element-binding Protein-1 Gene in Insulin Receptor Substrate-2-1- Mouse Liver. "jointly worked"
    J Biol Chem 276, 38337-38340 2001
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    Jpn Heart J 42, 627-631 2001
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    Peptides 22, 1913-1918 2001
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    Hypertension 39, 122-128 2002
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    Lancet 359, 133-135 2002
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  • Sodium calcium exchager plays a key role in alteration of cardiac function in response to pressure overload "jointly worked"
    FASEB J 16, 373-378 2002
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    J Mol Med 80, 105-116 2002
  • In Vivo klotho Gene Transfer Ameliorates Angiotensin Ⅱ-Induced Renal Damage. "jointly worked"
    Hypertension 39, 838-843 2002
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    Circ Res 90, 348-355 2002
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    Lab. Invest. 82, 87-96 2002
  • Angiotensin II and Catecholamines Increase Plasma Levels of 8-Epi-Prostaglandin F With Different Pressor Dependencies in Rats. "jointly worked"
    Hypertension 39, 149-154 2002
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    Journal of Hypertension 20, 55-62 2002
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    AJR(American Journal of Roentgenology) 178, 995-999 2002
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    Am. J. Respir. Cell Mol. Biol. 26, 246-253 2002
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    Diabetes 51, 536-540 2002
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    Journal of Cardiovascular Pharmacology 39, 503-512 2002
  • Increased insulin sensitibity despite lipodystrophy in Crebbp heterozygous mice. "jointly worked"
    Nature Genetics 30, 221-226 2002
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    Angiology 53, 105-108 2002
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    Circulation Resarch 90, 657-663 2002
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    Nature Medicine 8, 403-409 2002
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    J Hum Genet 47, 208-212 2002
  • Novel Point Mutation in the Cardiac Transcription Factor CSX/NKX2.5 Associated With Congenital Heart Disease. "jointly worked"
    Circulation Journal 66, 561-563 2002
  • Positron Emission Tomography Predicted Recovery of Complete A-V Nodal Dysfunction in a Patient With Cardiac Sarcoidosis. "jointly worked"
    Circulation 105, 1144-1145 2002
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    Recent Res. Devel. Immunology 4, 227-233 2002
  • Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes. "jointly worked"
    Circ Res. 90, 1004-1011 2002
  • Role of Fas/FasL Pathway in the Activation of Infiltrating Cells in Murine Acute Myocarditis Caused by Coxsackievirus B3. "jointly worked"
    Journal of the American College of Cardiology. 39, 1399-1403 2002
  • Regulation of angiogenesis by the aging suppressor gene Klotho. "jointly worked"
    Biochem Biophys Res Commun 293, 332-337 2002
  • Transcriptional Activation of the BNP Gene by Lipopolysaccharide is Mediated Through GATA Elements in Neonatal Rat Cardiac Myocytes. "jointly worked"
    J. Mol. Cell. Cardiol 34, 649-659 2002
  • Role of Fas/Fas Ligand Interaction in Ischemia-Induced Collateral Vessel Growth. "jointly worked"
    Hypertension Research 25, 577-582 2002
  • Csx/Nkx2-5 Is Required for Homeostasis and Survival of Cardiac Myocytes in the Adult Heart. "jointly worked"
    J Biol Chem 227, 24735-24743 2002
  • Novel Insight into the Role of Endothelial PAS Domain Protein 1 in Congestive Heart Failure. "jointly worked"
    J Mol Cell Cardiol 34, 703-707 2002
  • Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. "jointly worked"
    Human Molecular Genetics 11, 1775-1784 2002
  • Resistance to Neointimal Hyperplasia and Fatty Streak Formation in Mice With Adrenomedullin Overexpression. "jointly worked"
    Arterioscler Thromb Vasc Biol 22, 1310-1315 2002
  • Absence of Sterol Regulatory Element-binding Protein-1 (SREBP-1) Ameliorates Fatty Livers but Not Obesity or Insulin Resistance in Lepob/Lepob Mice. "jointly worked"
    J Biol Chem 277, 19353-19357 2002
  • Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. "jointly worked"
    Human Molecular Genetics 11, 1731-1742 2002
  • Phosphatidylinositol 3-Kinase. -A Key Regulator of Vascular Tone? "jointly worked"
    Circ Res. 91, 273-275 2002
  • Krppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. "jointly worked"
    Nature Medicine 8, 856-863 2002
  • A Role for Bone Morphogenetic Protein Signaling in Cardiomyocyte Differentiation. "jointly worked"
    Trends Cardiovasc Med 12, 263-269 2002
  • Constitutive Activation of Proto-Oncogen Protein p21 Inducues Cell Cycle Arrest in the G1 Phase in Contact-Inhibited Vascular Endothelial Cells. "jointly worked"
    Hypertens Res 25, 773-778 2002
  • Iron Overload Augments Angiotensin II-Induced Cardiac Fibrosis and Promotes Neointima Fromation."jointly worked"
    Circulation 106, 1840-1846 2002
  • Expression of Klotho protein in the inner ear. "jointly worked"
    Hear Res. 171, 103-110 2002
  • Disruption of adiponectin causes insulin resistance and neointimal fromation. "jointly worked"
    J Biol Chem 277, 25863-25866 2002
  • Attenuation of antigen-induced airway hyperresponsiveness in CGRP-deficient mice. "jointly worked"
    Am J Physiol Lung Cell Mol Physiol 283, L963-70 2002
  • Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors. "jointly worked"
    Arterioscler Thromb Vasc Biol 22, 1680-1685 2002
  • Diagnostic implications of circulating oxidized low density lipoprotein levels as a biochemical risk marker of coronary artery disease. "jointly worked"
    Clin Biochem 35, 347-353 2002
  • Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase. "jointly worked"
    J Biol Chem 277, 31893-31899 2002
  • Dual effects of the homeobox transcription factor Csx/ Nkx2-5 in cardiomyocytes.
    Biochem Biophys Res Commun 298(4) 493-500 2002
  • Caveolin-3 is up-regulated in the physiological left ventricular hypertrophy induced by voluntary exercise training in rats.
    Journal of Sports Science and Medicine 4 141-146 2002
  • G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cells.
    Biochem Biophys Res Commun 297(4) 1058-1061 2002
  • Nonselective cation currents regulate membrane potential of rabbit coronary arterial cell: modulation by lysophosphatidylcholine.
    Circulation 106 3111-3119 2002
  • Reactive oxygen species induce cardiomyocyte apoptosis partly through TNF-alpha.
    Cytokine 18 179-183 2002
  • Gene expression in fibroblasts and fibrosis involement in cardiac hypertrophy.
    Circulation Res. 91 1103-1113 2002
  • Continuous blockade of L-type Ca2+ channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats.
    Yunzeng ZOU, Tsutomu YAMAZAKI, Keiichi NAKAGAWA, Haruyasu YAMADA, Norio IRIGUCHI, Haruhiro TOKO, Hiroyuki TAKANO, Hiroshi AKAZAWA, Ryozo NAGAI, Issei KOMURO
    Hypertens Res 25(1) 117-124 2002
  • Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis.
    Inflamm Bowel Dis 8 330-339 2002
  • Massive pulmonary artery thrombosis, pulmonary hypertension and untreated atrial septal defect.
    Cardiology 97 53-54 2002
  • Increased prevalence of carotid atherosclerosis in hepatitis B virus carriers.
    Circulation 105 1028-1030 2002
  • Serum calcium concentration and carotid artery plaque: a population-based study.
    J Cardiol 39 151-157 2002
  • Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, OX40L and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy.
    Cardiovasc Pathol 11 166-170 2002
  • Mouse genetic evidence that tranilast reduces smooth muscle cell hyperplasia via p21(WAF1)-dependent pathway.
    Arterioscler Thromb Vasc Biol 22 1305-1309 2002
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    Am J Respir Cell Mol Biol 26 371-379 2002
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    J Biol Chem 277(40) 37487-37491 2002
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    Radiography 8 181-187 2002
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    Nature Medicine 8(11) 1288-1295 2002
  • Association between hepatitis C virus core protein and carotid atherosclerosis.
    Yuko Ishizaka, Nobukazu Ishizaka, Eiko Takahashi, Tadao Unuma, Ei-ichi Tooda, Hideki Hashimoto, Ryozo Nagai, Minoru Yamakado
    Circularion J 67(1) 26-30 2003
  • Characteristic Effects of α1-β1, 2-Adrenergic Blocking Agent, Carvedilol, on [Ca2+]i in ventricular myocytes compared with those of timolol and atenolol.
    Circulation J 67(1) 83-90 2003
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    J Biol Chem 278(4) 2461-2468 2003
  • Cytoskeletal reorganization induced by insulin: involvement of Grb2/Ash, Ras and phosphatidylinositol 3-kinase signalling.
    Genes Cells 8(1) 29-40 2003
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    Arterioscler Thromb Vasc Biol 23 295-301 2003
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    Hypertens Res 26 S79-S84 2003
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    Jpn Heart J 44(1) 139-144 2003
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    Eur J Pharmacol 464 79-86 2003
  • Regulation of smooth muscle phenotype.
    Curr Atheroscler Rep 5 214-222 2003
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    Circulation 107 e106-e107 2003
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    J Biol Chem 278(15) 12613-12617 2003
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    Eur J Pharmacology 468 47-58 2003
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    Gastroenterology 124 1315-1324 2003
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  • Adrenomedullin augments collateral development in response to acute ischemia.
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    Atherosclerosis 169 105-12 2003

Book

  • Enzymatic activities, activation by actin, and synthesis of cardiac atrial myodin : distinctive enzymatic properties compared with cardiac ventricular mysin.
    in 「Asvances in Myocardiology」edby Tajuddin et al. University Park Press, Baltimore 1980
  • Radioimmunossay of cardiac myosin light chain (]G0002[) in the serum following experimental myocardial infarction.
    in 「Advances in Myocardiology」 ed by Tajuddin et al. University Park Press, Baltimore 1980
  • Reconstitution of heavy chain and light chain I in cardiac subfragment I from hyperthyroid and euthyroid rabbit heart.
    In 「Advances in Myocardiology」 University Park Press, Baltimore 1983
  • Serial changes in cytosolic, mitochondrial and lysosomal enzymes and cardiac myosin light chain Ⅱ in plasma following coronary ligation in conscious closed-chest dogs.
    in 「Asvances in Myocardiology」 ed by Chazov E et al. , University Park Press, Baltimore 1983
  • Myocardial infarct size from serum cardiac myosin light chain.
    in 「Advances in Myocaridiology」, University Park, Baltimore 1983
  • Regulation of cardiac sarcoplasmic reticulum Ca2+-ATPase gene expression.
    in 「Molecular Biology of the Cardiovascular System」 ed. by R. Roberts & J. Sambrook Willey & Liss 1989
  • Molecular mechanisms for cardiac cellular hypertrophy due to mechanical stimuli.
    in 「Molecular Biology of the Myocardium」 ed by M. Tada. Japan Scientific Society Press, Tokyo 1992
  • Embryonic smooth muscle cell proliferation in the neointimas of arterio-and atheroscerotic aortas. Progess in Clinical Biochemistry.
    ed by Miyai M,Kanno T & I shikawaE.,Amsterdam. Elsevier Science 1992
  • Immunotherapy and reperfusion injury in the heart. in「Immunophamacology of the Heart」 ed.
    Academic Press 1993
  • Various phenothpes of smooth muscle cells involved in vascular remodeling as determined by expression of myosin heavy chain isoforms. in「The Adapted Heart」
    Raven Press 1994
Display all
Bookclose
  • Enzymatic activities, activation by actin, and synthesis of cardiac atrial myodin : distinctive enzymatic properties compared with cardiac ventricular mysin.
    in 「Asvances in Myocardiology」edby Tajuddin et al. University Park Press, Baltimore 1980
  • Radioimmunossay of cardiac myosin light chain (]G0002[) in the serum following experimental myocardial infarction.
    in 「Advances in Myocardiology」 ed by Tajuddin et al. University Park Press, Baltimore 1980
  • Reconstitution of heavy chain and light chain I in cardiac subfragment I from hyperthyroid and euthyroid rabbit heart.
    In 「Advances in Myocardiology」 University Park Press, Baltimore 1983
  • Serial changes in cytosolic, mitochondrial and lysosomal enzymes and cardiac myosin light chain Ⅱ in plasma following coronary ligation in conscious closed-chest dogs.
    in 「Asvances in Myocardiology」 ed by Chazov E et al. , University Park Press, Baltimore 1983
  • Myocardial infarct size from serum cardiac myosin light chain.
    in 「Advances in Myocaridiology」, University Park, Baltimore 1983
  • Regulation of cardiac sarcoplasmic reticulum Ca2+-ATPase gene expression.
    in 「Molecular Biology of the Cardiovascular System」 ed. by R. Roberts & J. Sambrook Willey & Liss 1989
  • Molecular mechanisms for cardiac cellular hypertrophy due to mechanical stimuli.
    in 「Molecular Biology of the Myocardium」 ed by M. Tada. Japan Scientific Society Press, Tokyo 1992
  • Embryonic smooth muscle cell proliferation in the neointimas of arterio-and atheroscerotic aortas. Progess in Clinical Biochemistry.
    ed by Miyai M,Kanno T & I shikawaE.,Amsterdam. Elsevier Science 1992
  • Immunotherapy and reperfusion injury in the heart. in「Immunophamacology of the Heart」 ed.
    Academic Press 1993
  • Various phenothpes of smooth muscle cells involved in vascular remodeling as determined by expression of myosin heavy chain isoforms. in「The Adapted Heart」
    Raven Press 1994
  • Phenotypic changes of smooth muscle in the rabbit carotid artery induced by postssternotic dilatation. in「The Adapted Heart」
    Raven Press 1994
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